Alprazolam combined with Clonazepam

Reports:


Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Pulmonary Oedema Hospitalization 1/1/2003 57 Female 1/4/2006 Brazil
Primary
Concomitant
Oedema Other Serious 11/1/2005 59 Female 1/4/2006 Brazil
Primary
Concomitant
Osteoarthritis Hospitalization 1/1/1997 51 Female 1/4/2006 Brazil
Primary
Concomitant
Blood Pressure Increased Hospitalization 1/1/2001 55 Female 1/6/2006 Brazil
Primary
Concomitant
Suicide Attempt Other Serious 12/2/2005 50 Female 1/10/2006 Other Health Professional United States
Primary
Secondary
Suicide Attempt Hospitalization 1/1/2005 58 Female 2/1/2006 Consumer United States
Primary
Secondary
Concomitant
Initial Insomnia 1/1/2005 47 Female 130 lb 1/5/2006 Consumer United States
Primary
Concomitant
Tremor Disability 31 Female 2/23/2006 Consumer Brazil
Primary
Secondary
Concomitant
Diplopia 3/16/2005 38 Female 2/28/2006 Consumer United States
Primary
Concomitant
Fatigue 10/2/2005 36 Male 2/28/2006 Consumer United States
Primary
Concomitant
Sepsis Other Serious 12/16/2005 46 Female 2/28/2006 Physician Brazil
Primary
Concomitant
Sepsis Other Serious 12/16/2005 46 Female 3/13/2006 Physician Brazil
Primary
Concomitant
Tinnitus Disability 8/27/2004 62 Male 195 lb 3/13/2006 Consumer United States
Primary
Concomitant
Pharmaceutical Product Complaint Other Serious 1/14/2006 41 Female 150 lb 3/22/2006 Pharmacist United States
Primary
Concomitant
Weight Increased Other Serious 12/1/2005 59 Female 3/27/2006 Physician United States
Primary
Concomitant
Vaginal Removal Of Intrauterine Foreign Body Other Serious 9/22/1999 74 Female 128 lb 4/10/2006 Physician United States
Primary
Concomitant
Urethral Disorder Other Serious 1/1/2001 57 Female 130 lb 4/12/2006 Lawyer United States
Primary
Concomitant
Pharmaceutical Product Complaint 4/3/2006 48 Female 4/11/2006 Pharmacist United States
Primary
Concomitant
Urinary Tract Disorder Hospitalization 9/30/2004 63 Male 240 lb 4/17/2006 United States
Primary
Concomitant
Urinary Retention Hospitalization 9/30/2004 63 Male 240 lb 5/5/2006 United States
Primary
Concomitant
Urethral Disorder Hospitalization 8/1/2000 57 Female 130 lb 5/11/2006 Physician United States
Primary
Concomitant
Pharmaceutical Product Complaint Hospitalization 63 Male 5/30/2006 Consumer United States
Primary
Concomitant
Drug Ineffective Hospitalization 10/28/2005 55 Male 126 lb 6/2/2006 Physician Brazil
Primary
Concomitant
Weight Decreased Hospitalization 9/30/2004 63 Male 240 lb 6/2/2006 United States
Primary
Concomitant
Drug Withdrawal Syndrome Hospitalization 9/14/2005 36 Male 247 lb 5/9/2006 Physician United States
Primary
Secondary
Concomitant
Respiratory Arrest Other Serious 6/26/2006 49 Female 7/10/2006 Physician Honduras
Primary
Secondary
Lethargy Other Serious 1/1/2006 49 Female 154 lb 7/19/2006 Physician Honduras
Primary
Secondary
Lethargy Other Serious 1/1/2006 49 Female 154 lb 7/20/2006 Physician Honduras
Primary
Secondary
Fall Hospitalization Male 7/14/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Leukopenia Required Intervention 8/17/2005 33 Male 1/5/2006 Consumer United States
Primary
Concomitant
Rhabdomyolysis Hospitalization 31 Female 7/28/2006 Physician Japan
Primary
Secondary
Concomitant
Suicide Attempt Other Serious 6/26/2006 49 Female 8/2/2006 Physician Honduras
Primary
Secondary
Concomitant
Sedation Hospitalization 5/1/2006 36 Female 118 lb 7/25/2006 Pharmacist United States
Primary
Secondary
Concomitant
Sedation Hospitalization 5/1/2006 36 Female 118 lb 7/25/2006 Pharmacist United States
Primary
Secondary
Concomitant
Speech Disorder Hospitalization 7/31/2005 34 Male 9/5/2006 Physician France
Primary
Concomitant
Pulmonary Oedema Death 45 Female 9/14/2006 Physician United States
Primary
Secondary
Angioneurotic Oedema Life Threatening 4/24/2006 58 Female 8/22/2006 Physician United States
Primary
Concomitant
Respiratory Arrest Death 1/1/2005 32 10/11/2006 Physician United States
Primary
Secondary
Unevaluable Event Other Serious 6/13/2006 33 Male 185 lb 10/24/2006 Physician Spain
Primary
Concomitant
Peridiverticular Abscess Hospitalization 8/17/2003 53 Female 10/24/2006 Physician United States
Primary
Concomitant
Therapeutic Response Unexpected With Drug Substitution Other Serious 8/29/2006 44 Female 118 lb 10/31/2006 Physician United States
Primary
Concomitant
Weight Decreased Hospitalization 9/30/2004 63 Male 240 lb 11/7/2006 United States
Primary
Concomitant
Urinary Incontinence Hospitalization 9/26/2006 43 Female 11/14/2006 China
Primary
Concomitant
Respiratory Arrest Death 32 NotSpecified 11/17/2006 Physician United States
Primary
Secondary
Vomiting Death 11/12/2002 24 Male 11/20/2006 United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 9/30/2004 63 Male 240 lb 11/20/2006 United States
Primary
Concomitant
Respiratory Arrest Death 1/1/2005 32 Unknown 11/21/2006 Physician United States
Primary
Secondary
Urinary Incontinence Hospitalization 9/26/2006 43 Female 11/27/2006 Other Health Professional China
Primary
Concomitant
Rhabdomyolysis Other Serious 11/10/2006 53 Male 11/23/2006 Physician Japan
Primary
Secondary
Concomitant
Suture Related Complication Hospitalization 8/1/2006 47 Female 12/5/2006 Brazil
Primary
Concomitant
Rhabdomyolysis Other Serious 11/9/2006 53 Male 12/5/2006 Physician Japan
Primary
Secondary
Concomitant
Urinary Incontinence Hospitalization 9/26/2006 43 Female 12/8/2006 Pharmacist Denmark
Primary
Concomitant
Memory Impairment Hospitalization 51 Male 12/19/2006 Other Health Professional Taiwan, Province Of China
Primary
Concomitant
Myalgia Other Serious 11/1/2006 33 Female 12/22/2006 Brazil
Primary
Concomitant
Memory Impairment Hospitalization 51 Male 12/28/2006 Other Health Professional Taiwan, Province Of China
Primary
Secondary
Concomitant
Tremor 12/15/2005 13 Male 150 lb 12/29/2006 Consumer United States
Primary
Secondary
Concomitant
Platelet Count Decreased Disability 1/4/2007 81 Female 126 lb 1/9/2007 Pharmacist United States
Primary
Concomitant
Intentional Overdose Death 11/12/2002 Male 1/22/2007 Consumer United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 11/17/2004 45 Female 230 lb 10/10/2006 Lawyer United States
Primary
Concomitant
Drug Toxicity Death 2/15/2007
Primary
Secondary
Cardio-respiratory Arrest Death 1/1/2005 32 Unknown 2/8/2007 Physician United States
Primary
Secondary
Drug Toxicity Death 2/21/2007 Belgium
Primary
Secondary
Scab 10/2/2006 51 Female 2/28/2007 Consumer United States
Primary
Concomitant
Peritoneal Effusion Hospitalization 8/17/2003 53 Female 3/5/2007 Physician United States
Primary
Concomitant
Drug Toxicity Death 3/12/2007
Primary
Secondary
Vestibular Disorder Other Serious 1/1/1990 35 Female 3/8/2007 Other Health Professional United States
Primary
Secondary
Drug Toxicity Death 3/16/2007 Belgium
Primary
Secondary
Renal Failure Hospitalization Female 3/9/2007 Other Health Professional United States
Primary
Secondary
Vision Blurred Other Serious 2/1/2007 Female 3/21/2007 Consumer Brazil
Primary
Concomitant
Intentional Overdose Death 11/12/2002 Male 3/27/2007 Lawyer United States
Primary
Secondary
Concomitant
Cardio-respiratory Arrest Death 1/1/2004 30 Unknown 3/26/2007 Pharmacist United States
Primary
Secondary
Vasoconstriction Hospitalization 8/12/2006 Female 4/10/2007 Consumer United States
Primary
Secondary
Concomitant
Sleep Walking Other Serious 1/4/2003 Female 4/13/2007 Consumer United States
Primary
Concomitant
Vestibular Disorder Hospitalization 35 Female 4/2/2007 Physician United States
Primary
Secondary
Arrhythmia Other Serious Male 4/30/2007 Other Health Professional Taiwan, Province Of China
Primary
Concomitant
Therapeutic Response Unexpected With Drug Substitution Other Serious Male 5/23/2007 United States
Primary
Concomitant
Weight Decreased Other Serious 38 Female 116 lb 5/29/2007 United States
Primary
Concomitant
Thrombosis In Device Death 5/18/2007 77 Female 6/19/2007 Pharmacist United States
Primary
Concomitant
Dependence Other Serious 1/1/2006 Male 185 lb 6/19/2007 Consumer United States
Primary
Concomitant
Varicose Vein Other Serious 4/17/2001 45 Female 6/22/2007 Lawyer United States
Primary
Concomitant
Poisoning Other Serious 5/25/2004 33 Female 7/9/2007 United States
Primary
Concomitant
Urinary Incontinence Other Serious 4/17/2001 45 Female 7/5/2007 Lawyer United States
Primary
Concomitant
Memory Impairment Hospitalization 51 Male 7/27/2007 Taiwan, Province Of China
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 7/1/2007 Female 122 lb 8/8/2007 Consumer United States
Primary
Concomitant
Parkinsonism Hospitalization 45 Female 8/9/2007 India
Primary
Concomitant
Urticaria Other Serious 1/1/2007 Female 189 lb 8/16/2007 Consumer United States
Primary
Secondary
Concomitant
Wound Complication Other Serious 8/1/2007 46 Female 8/20/2007 Consumer Belgium
Primary
Concomitant
Self Injurious Behaviour Other Serious 12/13/2006 17 Male 9/4/2007 Physician Japan
Primary
Concomitant
Renal Failure Other Serious 7/8/2007 Female 154 lb 9/7/2007 Mexico
Primary
Concomitant
Superficial Injury Of Eye Other Serious 53 Female 196 lb 9/8/2007 Consumer Brazil
Primary
Concomitant
Hypertension Other Serious 53 Female 196 lb 9/12/2007 Consumer Brazil
Primary
Concomitant
Diabetes Mellitus Hospitalization 4/18/2003 45 Male 287 lb 9/17/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 7/3/2007 Female 154 lb 9/18/2007 Mexico
Primary
Concomitant
Pathological Gambling 7/1/2000 Female 9/25/2007 Consumer United States
Primary
Concomitant
Urticaria Other Serious 12/29/2006 Female 196 lb 10/5/2007 Other Health Professional Canada
Primary
Concomitant
Lung Neoplasm Malignant Hospitalization 1/1/2006 51 Female 10/19/2007 United States
Primary
Concomitant
Tooth Fracture Other Serious 5/15/2007 65 Male 190 lb 10/11/2007 United States
Primary
Concomitant
Pathological Gambling 7/1/2000 Female 10/26/2007 Consumer United States
Primary
Concomitant
Respiratory Arrest Other Serious 32 10/29/2007 Physician United States
Primary
Secondary
Wrong Drug Administered 8/31/2007 United States
Primary
Secondary
Type 2 Diabetes Mellitus Hospitalization 5/1/2004 41 Female 147 lb 11/19/2007 Physician United States
Primary
Concomitant
Paraesthesia Other Serious 10/25/2007 Female 114 lb 11/30/2007
Primary
Concomitant
Weight Decreased 7/16/2007 63 Female 206 lb 10/8/2007 Consumer United States
Primary
Concomitant
Overdose Hospitalization 10/16/2007 Female 180 lb 12/14/2007 Consumer United States
Primary
Secondary
Concomitant
Drug Toxicity Death 52 Male 1/11/2008 Physician United States
Primary
Secondary
Paraesthesia Other Serious 10/25/2007 Female 114 lb 1/11/2008
Primary
Concomitant
Wrong Technique In Drug Usage Process Hospitalization 11/4/2007 47 Female 145 lb 1/10/2008 United States
Primary
Concomitant
Osteoarthritis Other Serious 1/1/2005 Male 199 lb 1/18/2008 Physician United States
Primary
Concomitant
Respiratory Arrest Death 1/1/2006 40 Female 1/18/2008 United States
Primary
Secondary
Respiratory Arrest Death 1/1/2006 24 Female 1/18/2008 United States
Primary
Secondary
Respiratory Arrest Death 52 Male 1/21/2008 United States
Primary
Secondary
Respiratory Arrest Death 40 Female 1/22/2008 Physician United States
Primary
Secondary
Type 2 Diabetes Mellitus Hospitalization 7/21/2005 Female 178 lb 1/16/2008 Consumer United States
Primary
Concomitant
Respiratory Arrest Death 52 Male 1/22/2008 Physician United States
Primary
Secondary
Respiratory Arrest Death 52 Male 1/22/2008 Physician United States
Primary
Secondary
Respiratory Arrest Death 24 Female 1/22/2008 Physician United States
Primary
Secondary
Weight Decreased Other Serious Male 311 lb 2/5/2008 Consumer United States
Primary
Concomitant
Lung Neoplasm Malignant Hospitalization 1/1/2006 51 Female 2/7/2008 United States
Primary
Concomitant
Respiratory Arrest Death 24 Female 1/31/2008 Physician United States
Primary
Secondary
Respiratory Arrest Death 40 Female 1/31/2008 Physician United States
Primary
Secondary
Drug Abuse Death 40 Female 2/8/2008 United States
Primary
Secondary
Osteoarthritis Other Serious 1/1/2005 Male 199 lb 2/14/2008 Physician United States
Primary
Concomitant
Cardio-respiratory Arrest Death 1/1/2006 24 Female 2/13/2008 Physician United States
Primary
Secondary
Cardio-respiratory Arrest Death 1/1/2006 40 Female 2/13/2008 Physician United States
Primary
Secondary
Cardio-respiratory Arrest Death 1/1/2006 52 Male 2/13/2008 Physician United States
Primary
Secondary
Suicide Attempt Life Threatening 2/3/2008 46 Male 2/21/2008 Physician Brazil
Primary
Concomitant
Weight Increased Hospitalization 8/1/2001 Female 150 lb 2/22/2008 Pharmacist United States
Primary
Secondary
Concomitant
Malaise Hospitalization 1/27/2008 85 Female 2/25/2008 Other Health Professional France
Primary
Secondary
Concomitant
Sedation Other Serious 40 Female 2/29/2008 Physician United States
Primary
Secondary
Concomitant
Weight Increased Hospitalization 8/1/2001 Female 150 lb 3/4/2008 Pharmacist United States
Primary
Secondary
Concomitant
Vertigo Hospitalization 1/27/2008 85 Female 3/6/2008 Physician France
Primary
Secondary
Concomitant
Depressed Mood Other Serious 3/11/2008 Female 153 lb 3/14/2008 United States
Primary
Concomitant
Rectal Haemorrhage 12/1/2007 Female 170 lb 3/15/2008 Consumer United States
Primary
Concomitant
Drug Level Decreased Other Serious 48 Female 3/19/2008 Norway
Primary
Secondary
Concomitant
Completed Suicide Death 3/27/2008 Physician United States
Primary
Secondary
Weight Increased Hospitalization 8/1/2001 Female 150 lb 4/1/2008 Pharmacist United States
Primary
Secondary
Concomitant
Pulmonary Congestion Other Serious 2/1/2008 Female 4/4/2008 United States
Primary
Concomitant
Respiratory Failure Hospitalization 11/4/2007 47 Female 145 lb 3/31/2008 United States
Primary
Concomitant
Weight Decreased Other Serious 8/1/2007 Male 311 lb 4/11/2008 Physician United States
Primary
Concomitant
Hypertension Other Serious 6/1/2007 Female 140 lb 4/25/2008 United States
Primary
Concomitant
Pathological Gambling Hospitalization 1/1/2002 Female 194 lb 4/28/2008 Consumer United States
Primary
Concomitant
Rhabdomyolysis Hospitalization 3/19/2008 44 Male 4/21/2008 Germany
Primary
Secondary
Concomitant
Tremor Other Serious 1/1/2007 84 Female 5/19/2008 Consumer United States
Primary
Secondary
Concomitant
Respiratory Arrest Life Threatening 24 Female 5/19/2008 Physician United States
Primary
Secondary
Urinary Tract Infection Other Serious 1/1/2003 70 Female 87 lb 5/27/2008 United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious Female 5/29/2008 Consumer Australia
Primary
Secondary
Concomitant
Interacting
Respiratory Arrest Other Serious 29 6/6/2008 Other Health Professional United States
Primary
Secondary
Weight Increased 1/1/2000 Female 161 lb 6/10/2008 Consumer United States
Primary
Concomitant
Substance Abuse Other Serious 44 Male 6/11/2008 Physician Canada
Primary
Secondary
Overdose Hospitalization 10/16/2007 Female 180 lb 6/12/2008 Consumer United States
Primary
Secondary
Concomitant