Alprazolam combined with Carvedilol

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Rhabdomyolysis Required Intervention 4/13/2006 76 Male 160 lb 4/18/2006 Pharmacist United States
Primary
Concomitant
Pyrexia Hospitalization 3/31/2006 Female 5/26/2006 Physician Japan
Primary
Secondary
Concomitant
Eye Swelling Required Intervention 12/1/2005 51 Female 159 lb 5/2/2006 Pharmacist United States
Primary
Concomitant
Pyrexia Hospitalization 3/31/2006 Female 6/7/2006 Physician Japan
Primary
Secondary
Concomitant
Pyrexia Hospitalization 3/31/2006 Female 159 lb 7/27/2006 Physician Japan
Primary
Secondary
Concomitant
Swelling Required Intervention 8/13/2006 64 Male 242 lb 9/20/2006 Pharmacist United States
Primary
Concomitant
Staphylococcal Infection Life Threatening 8/16/2006 54 Male 269 lb 10/27/2006 Physician Belgium
Primary
Concomitant
Troponin Increased Life Threatening 8/17/2006 54 Male 269 lb 11/3/2006 Physician Belgium
Primary
Concomitant
Staphylococcal Infection Life Threatening 8/17/2006 54 Male 269 lb 12/6/2006 Physician Belgium
Primary
Concomitant
Neuroleptic Malignant Syndrome Hospitalization 10/3/2006 Male 1/16/2007 Pharmacist United States
Primary
Concomitant
Myalgia Other Serious 62 Male 200 lb 6/2/2006 United States
Primary
Concomitant
Weight Decreased Hospitalization 87 Male 3/13/2007
Primary
Secondary
Concomitant
Face Oedema Other Serious Female 3/27/2007 Physician Korea, Republic Of
Primary
Concomitant
Tremor Hospitalization 10/27/2006 65 Female 4/25/2007 Pharmacist United States
Primary
Concomitant
Weight Decreased Other Serious 9/1/2003 87 Male 5/9/2007 Physician United States
Primary
Concomitant
Dyspnoea Hospitalization 7/10/2007 51 Female 10/12/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 9/7/2007 63 Male 165 lb 11/26/2007 Pharmacist United States
Primary
Concomitant
Tremor Other Serious 12/1/2007 Female 140 lb 3/18/2008 Consumer United States
Primary
Concomitant
Urinary Bladder Polyp Life Threatening 8/17/2006 Male 269 lb 3/28/2008 Belgium
Primary
Concomitant
Vomiting Other Serious 8/1/2007 Female 245 lb 5/2/2008 Physician United States
Primary
Concomitant
Tachycardia Other Serious 39 Female 5/13/2008 Physician United States
Primary
Concomitant
Vomiting Hospitalization 1/1/2007 Female 159 lb 5/23/2008 Physician United States
Primary
Secondary
Concomitant
Vomiting Other Serious 5/19/2008 Female 180 lb 5/30/2008 United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 1/1/2007 Female 159 lb 6/16/2008 Physician United States
Primary
Secondary
Concomitant
Pharmaceutical Product Complaint Other Serious 5/1/2008 Female 5/1/2008 Pharmacist United States
Primary
Concomitant
Left Ventricular Dysfunction Other Serious 39 Female 7/11/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Other Serious 4/21/2008 66 Male 155 lb 7/10/2008 Consumer United States
Primary
Concomitant
Haemorrhoids Hospitalization 7/14/2008 Female 143 lb 8/6/2008 Physician United States
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 8/1/2007 73 Female 8/12/2008 Pharmacist Spain
Primary
Secondary
Concomitant
Haemorrhoids Hospitalization 7/14/2008 Female 143 lb 8/15/2008 Physician United States
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 8/1/2007 73 Female 8/21/2008 Pharmacist Spain
Primary
Secondary
Concomitant
Swelling 2/26/2008 Female 276 lb 8/27/2008 Physician United States
Primary
Concomitant
Flushing Male 8/29/2008 United States
Primary
Concomitant
Vomiting Other Serious 4/21/2008 66 Male 155 lb 8/27/2008 United States
Primary
Concomitant
Therapeutic Agent Toxicity Required Intervention 4/21/2008 66 Male 155 lb 9/10/2008 United States
Primary
Concomitant
Dizziness 10/1/2007 74 Female 11/13/2008 Consumer United States
Primary
Concomitant
Stent Placement Hospitalization 67 Male 12/2/2008 Consumer United States
Primary
Secondary
Concomitant
Eye Haemorrhage Other Serious 3/1/2008 74 Male 168 lb 12/18/2008 Consumer United States
Primary
Secondary
Concomitant
Stent Placement Hospitalization 10/26/2008 67 Male 12/22/2008 Consumer United States
Primary
Secondary
Concomitant
Sleep Terror Hospitalization 1/1/2008 46 Female 135 lb 1/15/2009 Consumer United States
Primary
Concomitant
Product Quality Issue Death 7/7/2008 88 Male 171 lb 1/27/2009 United States
Primary
Concomitant
Tachycardia Hospitalization 41 Male 2/5/2009 Consumer United States
Primary
Concomitant
Swelling Face Other Serious 11/1/2008 68 Female 2/16/2009 Consumer United States
Primary
Concomitant
Myocardial Infarction Other Serious 1/31/2009 44 Female 117 lb 2/17/2009 Consumer Brazil
Primary
Secondary
Concomitant
Haemorrhoids Hospitalization 7/14/2008 Female 143 lb 2/19/2009 Physician United States
Primary
Secondary
Concomitant
Product Quality Issue Death 7/7/2008 88 Male 171 lb 2/10/2009 Consumer United States
Primary
Concomitant
Eye Haemorrhage Other Serious 3/1/2008 74 Male 168 lb 2/25/2009 Consumer United States
Primary
Secondary
Concomitant
Epilepsy Other Serious 1/30/2009 78 Male 2/27/2009 Physician Italy
Primary
Concomitant
Vaginal Infection Other Serious Female 135 lb 3/14/2009 Physician United States
Primary
Concomitant
Cardiac Failure Congestive Hospitalization 2/7/2009 84 Male 4/9/2009 Other Health Professional United States
Primary
Concomitant
Renal Failure Other Serious 1/1/2002 Female 222 lb 5/1/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Underdose Other Serious 1/1/2008 68 Female 223 lb 5/12/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Treatment Noncompliance Other Serious 1/1/2002 Female 222 lb 5/13/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Diabetes Mellitus Inadequate Control Hospitalization 9/10/2008 42 Male 5/21/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Underdose Other Serious 1/1/2008 68 Female 223 lb 5/27/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Death 64 Male 179 lb 6/5/2009 Lawyer United States
Primary
Concomitant
Renal Failure Other Serious 1/1/2002 Female 222 lb 6/17/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 7/14/2008 Female 143 lb 6/24/2009 Physician United States
Primary
Secondary
Concomitant
Renal Failure Acute Life Threatening 4/6/2009 85 Male 326 lb 7/1/2009 Other Health Professional United States
Primary
Concomitant
Sarcoma Metastatic Other Serious 12/1/2008 Male 155 lb 7/8/2009 Consumer United States
Primary
Secondary
Concomitant
Weight Increased Hospitalization 6/25/2002 49 Male 192 lb 7/14/2009 United States
Primary
Concomitant
Nervousness Hospitalization 5/1/2009 71 Female 111 lb 7/1/2009 Consumer United States
Primary
Concomitant
Surgery Death 73 Female 7/13/2009 United States
Primary
Concomitant
Injury Death 62 Male 7/13/2009 United States
Primary
Concomitant
Retroperitoneal Haemorrhage Hospitalization 4/28/2008 84 Male 7/22/2009 Pharmacist United States
Primary
Secondary
Concomitant
Retroperitoneal Haemorrhage Hospitalization 4/28/2008 84 Male 7/22/2009 Pharmacist United States
Primary
Secondary
Concomitant
Hypotension Other Serious 10/1/2008 56 Male 198 lb 8/10/2009 Other Health Professional Brazil
Primary
Secondary
Concomitant
Haemorrhoid Infection Hospitalization 7/14/2008 Female 143 lb 8/17/2009 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Death 62 Male 8/13/2009 United States
Primary
Concomitant
Therapeutic Agent Toxicity Death 64 Male 179 lb 8/13/2009 United States
Primary
Concomitant
Skin Burning Sensation Female 8/21/2009 United States
Primary
Concomitant
International Normalised Ratio Increased 9/1/2008 67 Male 8/22/2009 Consumer United States
Primary
Concomitant
Flatulence Other Serious 93 Male 8/18/2009 Consumer United States
Primary
Secondary
Concomitant
Weight Decreased Death 73 Female 8/28/2009 United States
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 65 Female 155 lb 8/24/2009 United States
Primary
Concomitant
Hypotension Other Serious 12/21/2007 78 Female 150 lb 9/3/2009 Lawyer United States
Primary
Concomitant
Tricuspid Valve Incompetence Hospitalization 62 Male 8/31/2009 United States
Primary
Concomitant
Weight Increased Other Serious 55 Male 254 lb 8/31/2009 Lawyer United States
Primary
Concomitant
Flatulence Other Serious 93 Male 150 lb 9/1/2009 Consumer United States
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Hospitalization 77 Female 9/2/2009 Lawyer United States
Primary
Concomitant
Unevaluable Event Hospitalization 77 Female 9/4/2009 United States
Primary
Concomitant
Incorrect Dose Administered 4/28/2007 Male 132 lb 9/11/2009 Consumer United States
Primary
Concomitant
Stent Placement Hospitalization 10/26/2008 67 Male 9/14/2009 Consumer United States
Primary
Secondary
Concomitant
Myopathy 3/1/2009 Male 250 lb 9/16/2009 Consumer United States
Primary
Secondary
Concomitant
Vomiting Female 270 lb 9/19/2009 United States
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 64 Female 155 lb 9/17/2009 United States
Primary
Concomitant
Weight Decreased Hospitalization 62 Male 9/18/2009 United States
Primary
Concomitant
Weight Increased Other Serious 55 Male 254 lb 9/21/2009 United States
Primary
Concomitant
Therapeutic Agent Toxicity Death 64 Male 179 lb 9/23/2009 Lawyer United States
Primary
Concomitant
Tricuspid Valve Incompetence Hospitalization 62 Male 203 lb 9/25/2009 United States
Primary
Concomitant
Therapeutic Agent Toxicity Required Intervention 64 Female 155 lb 9/24/2009 United States
Primary
Concomitant
Vomiting Hospitalization 77 Female 9/25/2009 United States
Primary
Concomitant
Therapeutic Agent Toxicity Required Intervention 64 Female 10/12/2009 United States
Primary
Concomitant
Weight Increased Hospitalization 62 Male 203 lb 10/10/2009 United States
Primary
Concomitant
Weight Increased Hospitalization 62 Male 203 lb 10/16/2009 United States
Primary
Concomitant
Weight Increased Hospitalization 72 Male 10/22/2009 United States
Primary
Concomitant
Vomiting Other Serious 2/21/2008 69 Female 150 lb 10/29/2009 Lawyer United States
Primary
Concomitant
Product Substitution Issue Hospitalization 10/4/2009 82 Female 11/3/2009 United States
Primary
Concomitant
Therapeutic Agent Toxicity Required Intervention 64 Female 10/26/2009 United States
Primary
Concomitant
Weight Increased Hospitalization 72 Male 10/26/2009 Lawyer United States
Primary
Concomitant
Weight Increased Hospitalization 72 Male 11/9/2009 Lawyer United States
Primary
Concomitant
Weight Decreased Death 73 Female 11/5/2009 United States
Primary
Concomitant
Vomiting Hospitalization 10/4/2009 82 Female 11/16/2009 United States
Primary
Concomitant
Vomiting Required Intervention 66 Male 11/10/2009 United States
Primary
Concomitant
Oesophagitis Hospitalization 8/1/2009 68 Male 11/11/2009 Germany
Primary
Concomitant
Therapeutic Agent Toxicity Required Intervention 65 Male 11/20/2009 United States
Primary
Concomitant
Weight Decreased Hospitalization 62 Male 203 lb 11/18/2009 Lawyer United States
Primary
Concomitant
Vomiting Hospitalization 79 Female 11/17/2009 United States
Primary
Concomitant
Weight Increased Hospitalization 72 Male 11/17/2009 Lawyer United States
Primary
Concomitant
Therapeutic Agent Toxicity Required Intervention 64 Female 155 lb 11/20/2009 United States
Primary
Concomitant
Parosmia 3/1/2009 62 Female 11/16/2009 United States
Primary
Concomitant
Peritonitis Bacterial Other Serious 3/5/2009 76 Male 168 lb 11/3/2009 Other Health Professional United States
Primary
Concomitant
Weight Decreased Hospitalization 62 Male 203 lb 12/9/2009 United States
Primary
Concomitant
Cardiomyopathy Other Serious 68 Male 12/11/2009 United States
Primary
Concomitant
Medication Residue Other Serious 1/1/2009 48 Male 256 lb 12/18/2009 Physician United States
Primary
Concomitant
Medication Residue Other Serious 1/1/2009 48 Male 256 lb 12/23/2009 Physician United States
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 73 Female 12/23/2009 Lawyer United States
Primary
Concomitant
Diabetes Mellitus Inadequate Control Hospitalization 1/5/2009 42 Male 12/31/2009 Other Health Professional Croatia (Local Name: Hrvatska)
Primary
Concomitant
Intra-abdominal Haemorrhage Hospitalization 10/4/2009 82 Female 1/4/2010 United States
Primary
Concomitant
Urinary Retention Other Serious 8/27/2009 61 Male 1/5/2010 Other Health Professional United States
Primary
Concomitant
Malaise Hospitalization 1/1/2009 53 Female 240 lb 1/15/2010 Consumer United States
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 12/4/2009 71 Male 12/6/2009 Pharmacist United States
Primary
Concomitant
Therapeutic Agent Toxicity Required Intervention 65 Male 1/13/2010 United States
Primary
Concomitant
Vomiting Hospitalization 65 Male 1/19/2010 United States
Primary
Concomitant
Toxic Epidermal Necrolysis Life Threatening 1/10/2010 53 Male 176 lb 1/28/2010 Other Health Professional United States
Primary
Concomitant
Weight Increased Hospitalization 72 Male 1/22/2010 Lawyer United States
Primary
Concomitant
Hypotension Hospitalization 4/1/2009 Female 215 lb 2/16/2010 Consumer United States
Primary
Concomitant
Hypertension Other Serious 8/4/2009 74 Female 143 lb 2/17/2010 Physician United States
Primary
Concomitant
Vomiting Life Threatening 12/14/2007 69 Male 3/4/2010 Lawyer United States
Primary
Secondary
Concomitant
Transient Ischaemic Attack Other Serious 8/4/2009 Female 143 lb 3/5/2010 Physician United States
Primary
Concomitant
Rash Macular Other Serious 3/4/2010 Female 175 lb 3/17/2010 Consumer United States
Primary
Concomitant
Transient Ischaemic Attack Other Serious 8/1/2009 Female 143 lb 3/29/2010 Physician United States
Primary
Concomitant
International Normalised Ratio Increased Other Serious 77 Female 3/19/2010 Pharmacist United States
Primary
Secondary
Concomitant
Splenomegaly Other Serious 11/2/2009 82 Female 3/25/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Unresponsive To Stimuli Other Serious 2/21/2008 69 Female 150 lb 4/13/2010 Other Health Professional United States
Primary
Concomitant
Weight Increased Hospitalization 5/22/2002 49 Male 192 lb 4/16/2010 United States
Primary
Concomitant
Hypertension Other Serious 8/4/2009 74 Female 143 lb 4/16/2010 Physician United States
Primary
Concomitant
Migraine Hospitalization 4/1/2010 35 Female 125 lb 4/22/2010 United States
Primary
Concomitant
Oesophagitis Hospitalization 2/8/2010 58 Female 140 lb 2/17/2010 Pharmacist United States
Primary
Secondary
Concomitant
Pallor Other Serious 12/3/2007 78 Female 150 lb 5/3/2010 Other Health Professional United States
Primary
Concomitant
Unresponsive To Stimuli Other Serious 2/21/2008 69 Female 150 lb 5/5/2010 Other Health Professional United States
Primary
Concomitant
Weight Decreased 10/1/2009 61 Male 5/13/2010 Spain
Primary
Secondary
Concomitant
Angina Unstable Hospitalization 3/6/2010 70 Female 190 lb 5/28/2010 Physician United States
Primary
Concomitant
Weight Decreased Hospitalization 73 Female 5/28/2010 United States
Primary
Concomitant
Vomiting Other Serious 1/2/2007 69 Male 187 lb 6/7/2010 Lawyer United States
Primary
Secondary
Concomitant
Myocardial Infarction Other Serious 1/31/2009 44 Female 117 lb 6/10/2010 Consumer Brazil
Primary
Secondary
Concomitant
Ischaemic Stroke Life Threatening 2/23/2010 60 Female 154 lb 6/21/2010 Physician Spain
Primary
Secondary
Concomitant
Vomiting Other Serious 2/1/2008 61 Male 6/22/2010 Lawyer United States
Primary
Concomitant
Coronary Artery Disease Death 12/19/2009 94 Female 6/24/2010 Other Health Professional United States
Primary
Concomitant
Gingival Recession 3/1/2009 55 Male 6/29/2010 Pharmacist United States
Primary
Concomitant

Drug Data