Allopurinol combined with Xarelto

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Lipase Increased Other Serious 6/1/2010 57 Male 7/27/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Lipase Increased Other Serious 6/1/2010 57 Male 8/17/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Loss Of Consciousness Other Serious 10/30/2011 67 Male 176 lb 11/30/2011 Physician Turkey
Primary
Concomitant
Post Procedural Haematoma Hospitalization 11/21/2011 70 Male 159 lb 12/19/2011 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Hyperkalaemia Hospitalization 12/18/2011 74 Male 191 lb 12/28/2011 Pharmacist United States
Primary
Concomitant
Thrombosis Hospitalization 12/6/2011 79 Female 113 lb 1/3/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 10/28/2011 84 Female 1/3/2012 Other Health Professional France
Primary
Concomitant
Renal Failure Acute Death 12/25/2011 77 Female 2/17/2012 Physician Belgium
Primary
Concomitant
Cerebrovascular Accident Death Male 2/17/2012 Physician Belgium
Primary
Concomitant
Coagulation Time Prolonged Hospitalization 12/1/2011 74 Male 152 lb 3/1/2012 Physician France
Primary
Concomitant
Interacting
Dehydration Other Serious 12/25/2011 77 Female 3/2/2012 Physician Belgium
Primary
Concomitant
Dehydration Other Serious 12/25/2011 77 Female 3/6/2012 Physician Belgium
Primary
Concomitant
Cardiac Failure Death 12/25/2011 77 Female 3/12/2012 Physician Belgium
Primary
Concomitant
Local Swelling Other Serious 2/1/2012 67 Female 3/14/2012 Consumer United States
Primary
Concomitant
Local Swelling Other Serious 2/1/2012 67 Female 3/15/2012 Other Health Professional United States
Primary
Concomitant
Interacting
Pulmonary Embolism Other Serious 3/11/2012 48 Female 291 lb 3/22/2012 Pharmacist United States
Primary
Concomitant
Renal Failure Hospitalization 12/22/2011 74 Male 191 lb 3/28/2012 Pharmacist United States
Primary
Secondary
Concomitant
Hypoglycaemia Hospitalization 12/22/2011 74 Male 192 lb 4/6/2012 Physician United States
Primary
Secondary
Concomitant
Disturbance In Attention Other Serious 3/2/2012 80 Male 181 lb 4/10/2012 Physician Germany
Primary
Concomitant
Hyperkalaemia Other Serious 12/22/2011 74 Male 191 lb 4/13/2012 Pharmacist United States
Primary
Secondary
Concomitant
Haematuria Other Serious 12/21/2011 74 Male 191 lb 4/17/2012 Physician United States
Primary
Secondary
Concomitant
Pulmonary Embolism Other Serious 3/11/2012 48 Female 291 lb 4/17/2012 Pharmacist United States
Primary
Concomitant
Tooth Discolouration Hospitalization 2/22/2012 91 Female 161 lb 4/17/2012 Physician Germany
Primary
Concomitant
Drug Interaction Hospitalization 12/1/2011 74 Male 152 lb 4/20/2012 Physician France
Primary
Concomitant
Interacting
Headache Disability 3/7/2012 74 Male 4/27/2012 Physician United States
Primary
Concomitant
Haemorrhage Intracranial Other Serious 3/7/2012 74 Male 5/4/2012 Physician United States
Primary
Concomitant
Pulmonary Embolism Hospitalization 2/16/2012 85 Male 5/18/2012 Physician France
Primary
Concomitant
Respiratory Disorder Death 3/7/2012 80 Male 5/22/2012 Physician France
Primary
Concomitant
Respiratory Disorder Hospitalization 3/7/2012 80 Male 5/24/2012 Other Health Professional France
Primary
Concomitant
Hiccups Hospitalization 63 Male 5/29/2012 Other Health Professional United Kingdom
Primary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 11/10/2011 74 Male 231 lb 6/4/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Epistaxis 5/10/2012 74 Male 161 lb 6/5/2012 Consumer United States
Primary
Concomitant
Blood Potassium Decreased Other Serious 3/1/2012 74 Female 163 lb 6/5/2012 Consumer United States
Primary
Secondary
Concomitant
Gastrointestinal Haemorrhage Other Serious 11/10/2011 74 Male 231 lb 6/6/2012 Other Health Professional United States
Primary
Concomitant
Interacting
Oedema Peripheral Hospitalization 1/20/2012 83 Female 128 lb 6/7/2012 Physician Germany
Primary
Concomitant
Fatigue Disability 2/25/2012 73 Female 6/8/2012 Physician Belgium
Primary
Concomitant
Adverse Event Hospitalization 3/1/2012 74 Female 163 lb 6/8/2012 Other Health Professional United States
Primary
Concomitant
Interacting
Gastrointestinal Haemorrhage Life Threatening 4/2/2012 88 Male 161 lb 6/8/2012 Physician Germany
Primary
Concomitant
Respiratory Disorder Hospitalization 3/7/2012 80 Male 6/11/2012 Other Health Professional France
Primary
Concomitant
Haemorrhage Hospitalization 5/15/2012 89 Male 176 lb 6/12/2012 Pharmacist Germany
Primary
Secondary
Concomitant
Blood Pressure Decreased Other Serious 1/1/2012 77 Female 165 lb 6/13/2012 Physician Germany
Primary
Concomitant
Adverse Event Other Serious 3/1/2012 74 Female 163 lb 6/18/2012 Consumer United States
Primary
Secondary
Concomitant
Gastrointestinal Haemorrhage Other Serious 11/12/2011 73 Male 231 lb 6/20/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Haemorrhage Hospitalization 5/15/2012 89 Male 176 lb 6/22/2012 Pharmacist Germany
Primary
Secondary
Concomitant
Dysarthria Hospitalization 11/12/2011 73 Male 231 lb 6/20/2012 Other Health Professional United States
Primary
Concomitant
Interacting
Face Oedema Hospitalization 1/20/2012 83 Female 128 lb 6/26/2012 Physician Germany
Primary
Secondary
Concomitant
Headache Other Serious 3/1/2012 74 Female 163 lb 7/3/2012 Consumer United States
Primary
Concomitant
Interacting
Adverse Event Hospitalization 3/1/2012 74 Female 163 lb 7/3/2012 Consumer United States
Primary
Secondary
Concomitant
Acute Abdomen Other Serious 6/28/2012 85 Female 138 lb 7/6/2012 Physician United States
Primary
Concomitant
Cardiac Tamponade Hospitalization 1/12/2011 76 Male 7/10/2012 Physician Slovenia
Primary
Concomitant
Dermatitis Allergic Other Serious 6/20/2012 80 Female 134 lb 7/12/2012 Other Health Professional Germany
Primary
Concomitant
Cardiac Tamponade Life Threatening 1/12/2011 76 Male 7/13/2012 Physician Slovenia
Primary
Concomitant
Blood Pressure Decreased Hospitalization 1/29/2012 77 Female 165 lb 7/19/2012 Physician Germany
Primary
Concomitant
Inappropriate Schedule Of Drug Administration Other Serious 7/11/2012 67 Male 275 lb 7/20/2012 Consumer United States
Primary
Concomitant
Interacting
Inappropriate Schedule Of Drug Administration Other Serious 7/1/2012 77 Male 204 lb 7/25/2012 Consumer United States
Primary
Secondary
Concomitant
Hepatic Enzyme Increased Hospitalization 7/27/2012 Consumer United States
Primary
Secondary
Concomitant
Constipation Other Serious 3/1/2012 74 Female 163 lb 7/30/2012 Consumer United States
Primary
Secondary
Concomitant
Hepatic Enzyme Increased Hospitalization 7/30/2012 Consumer United States
Primary
Secondary
Concomitant
Drug Prescribing Error Hospitalization 6/1/2012 79 Male 195 lb 7/31/2012 Physician United States
Primary
Concomitant
Incontinence Other Serious 6/1/2012 79 Female 8/3/2012 Physician Germany
Primary
Concomitant
Interacting
Mouth Ulceration Other Serious 5/7/2012 79 Male 174 lb 8/7/2012 Physician Germany
Primary
Concomitant
Vomiting Life Threatening 6/1/2012 79 Female 8/8/2012 Physician Germany
Primary
Concomitant
Interacting
Thrombosis In Device Hospitalization 7/26/2012 76 Male 8/13/2012 Physician France
Primary
Concomitant
Flatulence 7/1/2012 77 Male 204 lb 8/15/2012 Consumer United States
Primary
Secondary
Concomitant
Ischaemic Stroke Hospitalization 6/3/2012 72 Female 150 lb 8/22/2012 Physician Germany
Primary
Concomitant
Cardiac Failure Hospitalization 7/26/2012 76 Male 8/23/2012 Physician France
Primary
Concomitant
Hepatic Enzyme Increased Other Serious 6/19/2012 62 Female 165 lb 8/27/2012 Physician Germany
Primary
Concomitant
Embolic Stroke Hospitalization 5/29/2012 82 Male 132 lb 8/30/2012 Physician De
Primary
Concomitant
Oropharyngeal Pain Other Serious 7/2012 Male 205 lb 12/19/2012 Consumer Us
Primary
Secondary
Concomitant
Renal Failure Other Serious 74 Male 2/11/2013 Consumer Us
Primary
Secondary
Concomitant
Wound Haemorrhage Other Serious 7/6/2012 78 Male 231 lb 9/7/2012 Physician De
Primary
Concomitant
Faeces Discoloured Other Serious 2012 Male 180 lb 9/13/2012 Consumer Us
Primary
Concomitant
Melaena Hospitalization 9/5/2012 77 Female 148 lb 9/20/2012 Other Health Professional Us
Primary
Secondary
Concomitant
Subdural Haematoma Other Serious 2011 Male 9/29/2012 Physician Au
Primary
Secondary
Concomitant
Melaena Hospitalization 9/5/2012 77 Female 148 lb 9/21/2012 Other Health Professional Us
Primary
Concomitant
Interacting
Urinary Bladder Haemorrhage Other Serious 8/19/2012 75 Male 194 lb 9/25/2012 Consumer De
Primary
Secondary
Concomitant
Interacting
Renal Failure Acute Life Threatening Male 154 lb 9/26/2012 Other Health Professional De
Primary
Concomitant
Urticaria Hospitalization 5/10/2012 78 Male 187 lb 2/28/2013 Physician De
Primary
Concomitant
Gastrointestinal Haemorrhage Other Serious 10/3/2012 Other Health Professional Us
Primary
Secondary
Concomitant
Procedural Haemorrhage Hospitalization 6/2012 Male 198 lb 12/4/2012 Physician De
Primary
Secondary
Concomitant
Haemorrhage Intracranial Hospitalization 7/28/2012 67 Male 198 lb 11/5/2012 Physician De
Primary
Concomitant
Interacting
Coma Hospitalization 10/19/2012 90 Female 132 lb 11/12/2012 Physician De
Primary
Secondary
Concomitant
Red Blood Cell Count Decreased Other Serious Male 12/12/2012 Consumer Ca
Primary
Concomitant
Coma Death 10/19/2012 89 Female 132 lb 11/8/2012 Physician De
Primary
Concomitant
Interacting
Haemorrhage Hospitalization 3/28/2012 78 Male 11/5/2012 Physician Us
Primary
Concomitant
Tubulointerstitial Nephritis Hospitalization Male 12/31/2012 Physician De
Primary
Secondary
Concomitant
Ulcer Haemorrhage Hospitalization 6/12/2012 76 Male 150 lb 11/9/2012 Consumer Us
Primary
Concomitant
Puncture Site Haemorrhage Other Serious 2012 Male 170 lb 11/14/2012 Consumer Br
Primary
Secondary
Concomitant
Venous Occlusion Other Serious Male 1/3/2013 Physician De
Primary
Concomitant
Rebound Effect Other Serious 9/26/2012 84 Male 12/10/2012 Fr
Primary
Concomitant
Presyncope Hospitalization 9/9/2012 67 Male 197 lb 9/14/2012 Pharmacist Us
Secondary
Concomitant
Blood Creatinine Increased Other Serious 75 Male 12/5/2012 Physician Fr
Primary
Concomitant
Blood Creatinine Increased Other Serious 11/22/2012 81 Male 231 lb 3/22/2013 Physician De
Primary
Concomitant
Pulmonary Embolism Other Serious 10/24/2012 62 Female 289 lb 1/29/2013 Physician Us
Primary
Secondary
Concomitant
Scratch Other Serious 2012 Male 265 lb 1/10/2013 Consumer Us
Primary
Secondary
Concomitant
Pneumocystis Jirovecii Pneumonia Hospitalization 11/27/2012 63 Male 196 lb 4/18/2013 Physician Jp
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 10/24/2012 62 Female 289 lb 1/29/2013 Other Health Professional Us
Primary
Secondary
Concomitant
Withdrawal Syndrome Other Serious 1/17/2013 86 Female 132 lb 2/6/2013 Other Health Professional Gb
Primary
Concomitant
Myocardial Infarction Death 11/26/2012 81 Female 168 lb 2/20/2013 Pharmacist De
Primary
Concomitant
Product Quality Issue Hospitalization 1/14/2013 87 Female 2/18/2013 Other Health Professional Us
Primary
Concomitant
Interacting
Haemoglobin Decreased Life Threatening 6/2012 Male 3/12/2013 Physician Ca
Primary
Concomitant
Shock Haemorrhagic Hospitalization 1/12/2013 59 Male 5/6/2013 Other Health Professional Fr
Primary
Concomitant
Syncope Other Serious 1/21/2013 Male 3/6/2013 Consumer De
Primary
Concomitant
Drug Ineffective Other Serious 2013 Male 165 lb 5/24/2013 Physician Fr
Primary
Concomitant
Hypovolaemia Other Serious 1/4/2013 Male 3/15/2013 Other Health Professional Gb
Primary
Concomitant
Subdural Haematoma Death 2/13/2013 73 Male 176 lb 3/22/2013 Physician De
Primary
Concomitant
Renal Failure Acute Hospitalization 3/2013 Male 159 lb 3/29/2013 Pharmacist Us
Primary
Concomitant
Subcutaneous Haematoma Hospitalization 1/24/2012 74 Female 150 lb 5/6/2013 Physician De
Primary
Concomitant
Hospitalisation Hospitalization Male 4/17/2013 Consumer Us
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 2/1/2013 77 Male 181 lb 8/28/2013 Physician De
Primary
Concomitant
Urinary Tract Infection Hospitalization 1/30/2013 73 Male 176 lb 2/7/2013 Pharmacist Us
Primary
Concomitant
Ischaemic Stroke Death 2/25/2013 77 Male 4/22/2013 Other Health Professional Fr
Primary
Secondary
Concomitant
Ischaemic Stroke Death 2/25/2013 76 Male 4/26/2013 Other Health Professional Fr
Primary
Secondary
Concomitant
Decreased Appetite Hospitalization 3/20/2013 76 Male 179 lb 7/3/2013 Physician De
Primary
Concomitant
Wound Haemorrhage Other Serious 4/17/2013 83 Male 5/7/2013 Physician Fr
Primary
Concomitant
Weight Decreased Hospitalization 2012 Male 220 lb 9/26/2013 Consumer Us
Primary
Concomitant
Treatment Failure 3/13/2012 79 Male 186 lb 6/5/2013 Other Health Professional Us
Primary
Concomitant
Ischaemic Stroke Hospitalization 4/10/2013 91 Female 5/16/2013 Other Health Professional Fr
Primary
Concomitant
Medical Device Complication Other Serious 11/2012 62 Female 5/22/2013 Consumer Country Not Specified
Primary
Concomitant
Weight Increased Other Serious 2013 61 Male 255 lb 5/23/2013 Consumer Us
Primary
Concomitant
Plasma Cell Myeloma Death 5/5/2013 54 Male 160 lb 7/12/2013 Physician Us
Primary
Secondary
Concomitant
Rectal Haemorrhage Hospitalization 6/2/2013 58 Male 6/27/2013 Pharmacist Us
Primary
Secondary
Concomitant
Melaena Hospitalization 5/10/2013 Female 6/17/2013 Physician De
Primary
Concomitant
Pruritus Generalised Other Serious 2012 Male 193 lb 8/21/2013 Consumer Us
Primary
Secondary
Concomitant
Weight Decreased Other Serious 2012 68 Female 168 lb 9/2/2013 Consumer Us
Primary
Concomitant
Interacting
Diarrhoea Haemorrhagic Hospitalization 2/27/2013 Male 223 lb 7/3/2013 Physician Us
Primary
Concomitant
Drug Eruption Other Serious 6/5/2013 62 Male 137 lb 7/15/2013 Physician Jp
Primary
Secondary
Concomitant
Nausea Life Threatening Male 7/8/2013 Physician De
Primary
Concomitant
Renal Failure Acute Other Serious 6/26/2013 76 Male 238 lb 7/25/2013 Physician Us
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 73 Male 176 lb 7/12/2013 Pharmacist Us
Primary
Secondary
Concomitant
Melaena Other Serious 6/11/2013 86 Female 106 lb 7/10/2013 Physician Jp
Primary
Concomitant
Nausea Hospitalization 6/17/2013 81 Female 167 lb 7/15/2013 Physician Gb
Primary
Concomitant
Retinal Haemorrhage Disability Male 165 lb 7/15/2013 Physician De
Primary
Concomitant
International Normalised Ratio Increased Life Threatening 7/3/2013 77 Female 167 lb 8/20/2013 Pharmacist Us
Primary
Concomitant
Thrombosis Other Serious 7/5/2013 69 Male 250 lb 8/1/2013 Consumer Us
Primary
Secondary
Concomitant
Rectal Haemorrhage Hospitalization 6/24/2013 63 Male 227 lb 7/18/2013 Physician Gb
Primary
Concomitant
Renal Function Test Abnormal Other Serious 5/27/2013 78 Male 163 lb 7/22/2013 Physician De
Primary
Concomitant
Syncope Other Serious 5/27/2013 76 NotSpecified 7/25/2013 Other Health Professional Es
Primary
Concomitant
Renal Failure Other Serious 2013 85 Female 8/27/2013 Consumer Ca
Primary
Concomitant
Conjunctival Haemorrhage Hospitalization 7/1/2013 83 Female 129 lb 8/14/2013 Other Health Professional Us
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 6/2013 77 Male 245 lb 8/6/2013 Physician Fr
Primary
Concomitant
Prothrombin Time Prolonged Other Serious 74 Male 7/30/2013 Other Health Professional Ca
Primary
Secondary
Concomitant
Adrenal Mass Hospitalization 7/26/2013 54 Male 207 lb 7/31/2013 Pharmacist Us
Primary
Concomitant
Retroperitoneal Haemorrhage Hospitalization 6/2/2013 83 Female 164 lb 6/12/2013 Pharmacist Us
Primary
Concomitant
Haemoglobin Decreased Life Threatening 6/27/2013 87 Male 143 lb 8/22/2013 Physician Gb
Primary
Concomitant
Haematuria Other Serious 8/16/2013 82 Male 9/3/2013 Other Health Professional Us
Primary
Secondary
Concomitant
Haematuria Other Serious 8/16/2013 82 Male 8/30/2013 Other Health Professional Us
Primary
Concomitant
Interacting
Post Procedural Haemorrhage Hospitalization 7/18/2013 75 Male 9/3/2013 Other Health Professional Fr
Primary
Concomitant
Weight Increased Hospitalization 12/2012 71 Female 9/25/2013 Other Health Professional Us
Primary
Concomitant
Visual Impairment Death Male 9/27/2013 Physician At
Primary
Concomitant
Interacting

Drug Data