Allopurinol combined with Warfarin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Transient Ischaemic Attack Other Serious 12/11/2002 78 Male 209 lb 1/13/2006 Physician United States
Primary
Concomitant
Sepsis Hospitalization 6/13/2005 74 Male 1/10/2006 United Kingdom
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 1/1/2006 66 Male 211 lb 1/10/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Hospitalization 1/1/2006 66 Male 211 lb 1/9/2006 Physician United States
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Hospitalization 1/1/2006 66 Male 211 lb 1/10/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Rash Hospitalization 10/20/2005 71 Male 11/5/2005 Pharmacist United States
Primary
Secondary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 12/9/2005 84 Male 201 lb 12/16/2005 Other Health Professional United States
Primary
Concomitant
Ventricular Fibrillation Required Intervention 9/19/2005 69 Male 228 lb 2/6/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Poor Peripheral Circulation Hospitalization 4/20/2005 Male 2/21/2006 Consumer United States
Primary
Concomitant
Somnolence 5/22/2005 82 Male 172 lb 1/5/2006 United States
Primary
Concomitant
Myocardial Infarction Other Serious 1/1/2001 75 Male 181 lb 2/24/2006 Lawyer United States
Primary
Concomitant
Hepatitis Toxic Other Serious 10/18/2005 77 Male 3/2/2006 Physician Spain
Primary
Concomitant
Transient Ischaemic Attack Disability 7/14/2001 49 Male 326 lb 3/6/2006 Lawyer United States
Primary
Concomitant
Transient Ischaemic Attack Other Serious 7/14/2001 49 Male 326 lb 3/7/2006 Physician United States
Primary
Secondary
Concomitant
Skin Lesion Hospitalization 11/30/2005 77 214 lb 2/10/2006 Pharmacist United States
Primary
Concomitant
International Normalised Ratio Increased Life Threatening 3/3/2006 56 Female 3/16/2006 Ireland
Primary
Concomitant
Aortic Dissection Death Male 3/29/2006
Primary
Secondary
Gynaecomastia Hospitalization 1/1/2006 59 Male 4/10/2006 Australia
Primary
Concomitant
White Blood Cell Count Abnormal Other Serious 2/24/2006 Female 4/13/2006 Physician United States
Primary
Concomitant
Vomiting 1/1/2005 46 Female 154 lb 1/25/2006 Other Health Professional United States
Primary
Concomitant
Vitamin B12 Increased Other Serious 2/8/2006 Female 172 lb 4/24/2006 Physician Australia
Primary
Secondary
Concomitant
Therapeutic Response Decreased Other Serious 1/1/2006 Female 172 lb 5/18/2006 Physician Australia
Primary
Secondary
Concomitant
Hypoglycaemic Coma Hospitalization 5/29/2006 Male 6/8/2006 Pharmacist Japan
Primary
Concomitant
Ventricular Tachycardia Hospitalization 69 Female 176 lb 6/8/2006 Canada
Primary
Concomitant
Hepatitis Hospitalization 7/1/2006 49 Female 9/7/2006 Physician New Zealand
Primary
Concomitant
Hepatitis Hospitalization 7/1/2006 49 Female 1/29/2007 Physician New Zealand
Primary
Concomitant
International Normalised Ratio Increased Hospitalization 3/20/2007 52 Male 4/9/2007 Denmark
Primary
Concomitant
Rash Hospitalization 10/20/2005 71 Male 4/23/2007 Pharmacist United States
Primary
Secondary
Concomitant
International Normalised Ratio Increased Other Serious 71 Female 5/3/2007
Primary
Secondary
Concomitant
Somnolence Other Serious 1/1/2003 79 Male 77 lb 5/13/2007 Physician Japan
Primary
Concomitant
Neuropathy Peripheral 5/2/2007 Female 5/11/2007 Pharmacist United States
Primary
Concomitant
Electrocardiogram Qt Prolonged Life Threatening 7/30/2007 70 Female 8/9/2007 Physician Japan
Primary
Concomitant
Drug Interaction Other Serious 68 Male 8/16/2007 Sweden
Primary
Concomitant
Interacting
Drug Interaction Death 74 Female 8/16/2007 Sweden
Primary
Secondary
Concomitant
Interacting
Drug Interaction Other Serious 87 Male 8/16/2007 Sweden
Primary
Concomitant
Interacting
Drug Interaction Death 79 Female 8/16/2007 Sweden
Primary
Concomitant
Interacting
Encephalopathy Life Threatening 10/20/2004 73 Male 8/17/2007 Other Health Professional Japan
Primary
Concomitant
Blood Creatinine Increased Other Serious 7/20/2007 87 Female 8/21/2007 Physician Japan
Primary
Secondary
Concomitant
Faeces Discoloured Hospitalization 82 Male 8/21/2007 Physician Japan
Primary
Secondary
Concomitant
Thrombosis Required Intervention 6/17/2007 35 Male 88 lb 6/20/2007 Pharmacist United States
Primary
Secondary
Concomitant
Skin Discolouration Other Serious 8/15/2007 87 Male 190 lb 8/29/2007 Consumer United States
Primary
Concomitant
Interacting
Cardiac Failure Hospitalization 2/7/2007 76 Male 8/29/2007 Physician Japan
Primary
Concomitant
Skin Laceration Other Serious 6/1/2007 Female 172 lb 8/29/2007 Physician United States
Primary
Concomitant
Renal Impairment Other Serious 7/20/2007 87 Female 8/30/2007 Physician Japan
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 2/1/2007 53 Male 9/7/2007 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Heart Rate Decreased Hospitalization 7/1/2007 71 Male 9/10/2007 Consumer United States
Primary
Concomitant
Mucosal Inflammation Hospitalization 9/13/2007 Male 1/23/2008 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/1999 60 Female 1/25/2008 Other Health Professional United States
Primary
Concomitant
Pain In Extremity Hospitalization 1/1/1983 Female 2/7/2008 Consumer United States
Primary
Concomitant
Pneumonia Death 9/13/2004 77 Female 220 lb 4/18/2008 United Kingdom
Primary
Concomitant
Hepatitis Hospitalization 6/1/2006 49 Female 5/22/2008 Physician New Zealand
Primary
Concomitant
Wound Complication Other Serious 1/1/2000 Female 6/4/2008 Physician United States
Primary
Concomitant
Myocardial Infarction Hospitalization 5/1/2007 Female 6/16/2008 Japan
Primary
Concomitant
Febrile Neutropenia Other Serious 2/15/2008 60 Male 9/16/2008 Physician United States
Primary
Secondary
Concomitant
Malaise Other Serious 2/15/2008 60 Male 9/29/2008 Physician United States
Primary
Secondary
Concomitant
Toxic Skin Eruption Other Serious 11/14/2008 67 Male 12/12/2008 Japan
Primary
Concomitant
Ascites Hospitalization 5/30/2008 Male 12/31/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Emphysema 11/1/2008 Male 1/12/2009 Consumer
Primary
Concomitant
Electrocardiogram Qt Interval Abnormal Other Serious 3/7/2008 71 Male 1/13/2009 Other Health Professional Ireland
Primary
Secondary
Concomitant
Blindness Other Serious Male 170 lb 1/23/2009 Consumer United States
Primary
Secondary
Concomitant
Urine Output Decreased Other Serious 9/1/2006 Male 195 lb 1/26/2009 Lawyer United States
Primary
Secondary
Concomitant
Stomatitis Death 6/1/2008 80 Female 1/28/2009 Pharmacist Japan
Primary
Concomitant
Proteinuria Other Serious 1/1/2007 Female 235 lb 2/5/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Arterial Haemorrhage Life Threatening 10/30/2007 Male 157 lb 2/6/2009 Physician Canada
Primary
Concomitant
Pneumonia Death 1/3/2009 Female 2/6/2009 Physician United States
Primary
Concomitant
Flushing 12/4/2008 Male 2/24/2009 United States
Primary
Concomitant
Renal Failure Hospitalization 2/10/2009 Male 255 lb 3/4/2009 Physician United States
Primary
Concomitant
Right Ventricular Failure Hospitalization 12/26/2008 Male 255 lb 3/5/2009 Physician United States
Primary
Concomitant
Renal Failure Hospitalization 2/10/2009 Male 255 lb 3/19/2009 Physician United States
Primary
Concomitant
Vomiting Life Threatening 3/11/2009 54 Female 160 lb 3/30/2009 Pharmacist United States
Primary
Concomitant
Dyspnoea Death 3/28/2009 Female 4/8/2009 Consumer Italy
Primary
Concomitant
Hypoglycaemia Required Intervention 8/21/2008 60 Female 200 lb 11/13/2008 Pharmacist United States
Primary
Concomitant
Stent Placement Other Serious Male 170 lb 4/22/2009 Physician United States
Primary
Secondary
Concomitant
Transient Ischaemic Attack Other Serious 2/13/2009 5/7/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Transient Ischaemic Attack Other Serious 2/13/2009 76 5/20/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Respiratory Tract Infection Hospitalization 3/3/2009 Male 206 lb 6/4/2009 Physician Ireland
Primary
Secondary
Concomitant
Ascites Hospitalization 5/30/2008 Male 6/2/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Gastric Perforation Life Threatening 7/19/2008 Male 6/2/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Pulmonary Fibrosis Hospitalization 11/27/2008 77 Female 183 lb 6/16/2009 Pharmacist United States
Primary
Concomitant
Vomiting Death 57 Male 6/17/2009 United States
Primary
Concomitant
Transient Ischaemic Attack Other Serious 2/13/2009 76 6/24/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Stent Placement Other Serious Male 170 lb 7/2/2009 Physician United States
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 6/21/2009 74 7/10/2009 Other Health Professional Sweden
Primary
Secondary
Concomitant
Respiratory Disorder Other Serious 1/1/2009 81 Male 8/11/2009 Consumer United States
Primary
Concomitant
Rash Generalised Other Serious 7/29/2009 58 Male 8/12/2009 Other Health Professional United States
Primary
Concomitant
Pancreatitis Hospitalization 7/25/2009 89 Female 234 lb 8/7/2009 Pharmacist United States
Primary
Concomitant
Unevaluable Event Hospitalization 47 Male 8/11/2009 United States
Primary
Concomitant
Varices Oesophageal Hospitalization 11/23/2007 67 Male 8/12/2009 Consumer United States
Primary
Concomitant
Vomiting Hospitalization 46 Male 8/13/2009 United States
Primary
Concomitant
Vomiting Hospitalization 7/1/2007 48 Male 8/12/2009 United States
Primary
Concomitant
Myalgia Other Serious 6/28/2009 71 8/19/2009 Canada
Primary
Concomitant
Interacting
Pruritus 12/1/2008 Male 8/22/2009 United States
Primary
Concomitant
Pruritus Male 8/22/2009 United States
Primary
Concomitant
Palpitations 3/24/2009 Male 8/22/2009 United States
Primary
Concomitant
Sensory Disturbance 4/1/2009 Male 230 lb 8/23/2009 Consumer United States
Primary
Secondary
Concomitant
Rash Generalised Other Serious 7/29/2009 58 Male 8/25/2009 Other Health Professional United States
Primary
Concomitant
Vomiting Hospitalization 7/1/2007 48 Male 456 lb 9/4/2009 United States
Primary
Concomitant
Surgery Hospitalization 47 Male 9/3/2009 United States
Primary
Concomitant
Multiple Injuries Hospitalization 46 Male 9/3/2009 Lawyer United States
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Hospitalization 11/23/2007 66 Male 802 lb 9/3/2009 Lawyer United States
Primary
Concomitant
Upper Respiratory Tract Infection Death 74 Male 196 lb 9/10/2009 United States
Primary
Concomitant
Weight Increased Other Serious 31 Male 9/15/2009 United States
Primary
Concomitant
Liver Disorder Hospitalization 8/13/2009 57 9/22/2009 Physician Japan
Primary
Concomitant
Pulmonary Oedema Life Threatening 7/31/2009 Female 185 lb 9/25/2009 Physician
Primary
Secondary
Concomitant
International Normalised Ratio Increased Life Threatening 8/21/2009 Male 206 lb 8/24/2009 Pharmacist United States
Primary
Concomitant
Retroperitoneal Haemorrhage Required Intervention 11/18/2008 80 Female 216 lb 11/19/2008 Pharmacist United States
Primary
Concomitant
Weight Increased Hospitalization 46 Male 9/18/2009 Consumer United States
Primary
Concomitant
Weight Increased Hospitalization 7/1/2007 48 Male 456 lb 9/17/2009 Consumer United States
Primary
Concomitant
Surgery Other Serious 61 Male 9/16/2009 United States
Primary
Concomitant
Varices Oesophageal Hospitalization 11/23/2007 64 Male 364 lb 9/18/2009 United States
Primary
Concomitant
Hepatitis Hospitalization 8/17/2009 Male 165 lb 9/30/2009 Physician United Kingdom
Primary
Concomitant
Hepatitis Hospitalization 8/17/2009 Male 165 lb 10/8/2009 Physician United Kingdom
Primary
Concomitant
Pancreatitis Hospitalization 9/1/2009 66 Male 10/28/2009 Consumer United States
Primary
Concomitant
Pancreatitis Chronic Hospitalization 9/1/2009 66 Male 198 lb 11/4/2009 Physician United States
Primary
Concomitant
Renal Impairment Hospitalization 83 Female 101 lb 11/13/2009 Physician Japan
Primary
Secondary
Concomitant
Peritonitis Bacterial Other Serious 1/1/2009 62 Male 11/3/2009 Other Health Professional United States
Primary
Concomitant
Peritonitis Bacterial Hospitalization 75 Male 11/3/2009 Other Health Professional United States
Primary
Concomitant
Urinary Retention Hospitalization 61 Male 12/10/2009 United States
Primary
Concomitant
Unevaluable Event Hospitalization 79 Male 12/11/2009 United States
Primary
Concomitant
Upper Respiratory Tract Infection Hospitalization 74 Male 196 lb 12/11/2009 United States
Primary
Concomitant
Scratch Hospitalization 12/4/2009 Male 170 lb 12/29/2009 Consumer United States
Primary
Concomitant
Prothrombin Time Prolonged Other Serious 81 Male 12/31/2009 Other Health Professional Japan
Primary
Interacting
Hepatitis Hospitalization 8/17/2009 Male 163 lb 1/4/2010 Physician United Kingdom
Primary
Concomitant
International Normalised Ratio Increased Hospitalization 9/8/2009 71 Male 198 lb 1/5/2010 Other Health Professional United Kingdom
Primary
Concomitant
Respiratory Arrest Other Serious 12/17/2007 73 Female 1/7/2010 Lawyer United States
Primary
Concomitant
Weight Increased Other Serious 6/1/2009 Male 220 lb 1/8/2010 Consumer United States
Primary
Concomitant
Pain Other Serious 6/19/2007 60 Male 1/12/2010 Other Health Professional United Kingdom
Primary
Concomitant
Tooth Disorder Other Serious 1/1/2002 Male 1/15/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Febrile Neutropenia Other Serious 6/4/2008 1/20/2010 Physician Japan
Primary
Secondary
Concomitant
Transient Ischaemic Attack Other Serious 2/24/2009 Female 1/21/2010 Other Health Professional United Kingdom
Primary
Concomitant
Ventricular Extrasystoles Other Serious 10/25/2009 70 Male 1/22/2010 Other Health Professional United States
Primary
Concomitant
Syncope Other Serious 1/1/2009 Male 183 lb 1/22/2010 Pharmacist United States
Primary
Concomitant
Interacting
Transient Ischaemic Attack Other Serious 2/24/2009 Female 1/22/2010 Other Health Professional United Kingdom
Primary
Concomitant
Weight Decreased Hospitalization 1/1/2008 Male 366 lb 1/21/2010 Consumer United States
Primary
Concomitant
Vomiting Other Serious 1/1/2007 63 Male 1/25/2010 Lawyer United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2003 Male 250 lb 2/3/2010 Other Health Professional United States
Primary
Concomitant
Weight Increased Other Serious 12/1/2007 74 Female 163 lb 2/3/2010 Other Health Professional United States
Primary
Concomitant
Syncope Hospitalization Female 220 lb 2/19/2010 Consumer United States
Primary
Concomitant
Waist Circumference Increased Hospitalization 72 Male 256 lb 2/5/2010 United States
Primary
Concomitant
Ventricular Tachycardia Life Threatening 2/4/2010 Male 2/28/2010 Physician Japan
Primary
Concomitant
Weight Decreased Other Serious 1/1/2003 Male 250 lb 3/1/2010 Other Health Professional United States
Primary
Concomitant
Subdural Haematoma Death 7/27/2009 79 Male 3/5/2010 Pharmacist United States
Primary
Concomitant
Death Death Male 3/10/2010 Consumer United States
Primary
Concomitant
Vomiting Hospitalization 6/1/2007 74 Male 3/25/2010 United States
Primary
Concomitant
Pulmonary Infarction Life Threatening 3/4/2005 46 Male 4/14/2010 Physician Japan
Primary
Secondary
Concomitant
International Normalised Ratio Increased Hospitalization 3/23/2010 69 4/16/2010 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Renal Failure Other Serious 2/6/2008 51 Male 163 lb 4/16/2010 Other Health Professional United States
Primary
Concomitant
International Normalised Ratio Increased Hospitalization 3/23/2010 69 4/22/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Urine Output Decreased Hospitalization 4/22/2010 84 Male 253 lb 5/7/2010 United States
Primary
Secondary
Concomitant
Sepsis Other Serious 1/1/2007 66 Female 5/7/2010 Lawyer United States
Primary
Concomitant

Drug Data