Allopurinol combined with Warfarin Sodium

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
International Normalised Ratio Increased Hospitalization 12/6/2005 55 Female 432 lb 12/16/2005 Pharmacist United States
Primary
Secondary
Liver Disorder Hospitalization 12/14/2004 72 Female 1/6/2006 Physician Japan
Primary
Concomitant
Nausea Other Serious 40 Male 218 lb 1/12/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Therapy Non-responder Other Serious Male 225 lb 1/18/2006 United States
Primary
Concomitant
Death Other Serious 12/25/2004 74 Male 1/20/2006 Pharmacist United States
Primary
Concomitant
Aortic Dissection Death 4/5/2005 Male 2/1/2006 Consumer United Kingdom
Primary
Secondary
Aortic Dissection Death 4/5/2005 Male 2/1/2006 Consumer United Kingdom
Primary
Secondary
Renal Failure Hospitalization 11/1/2005 62 Male 2/3/2006 Sweden
Primary
Concomitant
Sinus Bradycardia Life Threatening 9/7/2005 74 Male 2/10/2006 Other Health Professional Japan
Primary
Concomitant
Ventricular Fibrillation Required Intervention 9/19/2005 69 Male 228 lb 2/17/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Somnolence Hospitalization 1/5/2006 84 Male 2/26/2006 Other Health Professional France
Primary
Secondary
Concomitant
Visual Disturbance 11/8/2005 65 Male 340 lb 1/20/2006 Other Health Professional United States
Primary
Concomitant
Fatigue 1/1/2005 57 Female 182 lb 1/25/2006 Other Health Professional United States
Primary
Concomitant
Oral Discomfort 1/1/2005 72 Female 148 lb 1/25/2006 Other Health Professional United States
Primary
Concomitant
Hyperthyroidism Other Serious 6/26/2005 47 Male 4/13/2006 Japan
Primary
Concomitant
Retroperitoneal Haemorrhage Other Serious 3/8/2006 Male 164 lb 4/24/2006 Physician Japan
Primary
Concomitant
Interacting
Therapy Non-responder Hospitalization 11/16/2005 29 Male 4/19/2006 Physician Australia
Primary
Concomitant
Pneumonia Life Threatening 3/3/2006 56 Female 4/26/2006 Pharmacist Ireland
Primary
Concomitant
Urinary Tract Infection Required Intervention 3/16/2006 74 Male 5/9/2006 Other Health Professional United States
Primary
Concomitant
Haemorrhage Hospitalization 3/6/2006 65 Male 5/11/2006 United States
Primary
Secondary
Concomitant
Intestinal Perforation Death 1/13/2006 74 Male 5/5/2006 Physician United States
Primary
Concomitant
Thrombocytopenia Other Serious 1/26/2006 70 Male 5/12/2006 Pharmacist United Kingdom
Primary
Concomitant
Periorbital Oedema Hospitalization 4/4/2006 84 Female 5/24/2006 Other Health Professional France
Primary
Concomitant
Interacting
Cerebral Haemorrhage Hospitalization 3/18/2005 48 Female 5/26/2006 Physician Japan
Primary
Secondary
Concomitant
Rash Other Serious 1/5/2006 59 Female 106 lb 5/23/2006 Japan
Primary
Concomitant
Blood Parathyroid Hormone Increased 8/22/2005 Male 3/13/2006 United States
Primary
Secondary
Concomitant
Blood Parathyroid Hormone Increased 8/22/2005 Male 3/13/2006 United States
Primary
Secondary
Concomitant
Initial Insomnia 1/1/2006 82 Male 175 lb 4/3/2006 Consumer United States
Primary
Concomitant
Urticaria Generalised Hospitalization 2/20/2005 54 Female 130 lb 5/25/2006 Other Health Professional United Kingdom
Primary
Concomitant
Ventricular Tachycardia Life Threatening 11/17/2005 Female 6/7/2006 Physician Japan
Primary
Secondary
Concomitant
Interacting
Muscular Weakness Other Serious 12/1/2005 60 Female 320 lb 4/20/2006 Consumer United States
Primary
Concomitant
Hypoglycaemic Coma Hospitalization 5/29/2006 Male 6/14/2006 Pharmacist Japan
Primary
Secondary
Concomitant
Chest Pain Hospitalization 10/31/2004 89 Female 6/8/2006 Other Health Professional Sweden
Primary
Secondary
Concomitant
Postoperative Wound Infection Life Threatening 6/2/2006 74 Male 6/16/2006 Pharmacist Japan
Primary
Secondary
Concomitant
Viral Infection Hospitalization 69 Female 176 lb 6/16/2006 Canada
Primary
Concomitant
Interacting
Drug Effect Decreased 63 Male 4/25/2006 United States
Primary
Concomitant
Therapeutic Response Decreased Other Serious 1/1/2006 Female 172 lb 6/21/2006 Physician Australia
Primary
Secondary
Concomitant
Platelet Count Decreased Other Serious 80 Male 6/26/2006 Consumer Japan
Primary
Secondary
Concomitant
Right Ventricular Failure Death 10/26/2004 45 Female 116 lb 6/22/2006 Physician Japan
Primary
Concomitant
Vomiting Hospitalization 2/10/2004 81 Male 157 lb 7/2/2006 Physician Japan
Primary
Concomitant
Somnolence Other Serious 1/1/2006 61 Male 209 lb 6/28/2006 United States
Primary
Concomitant
Periorbital Oedema Other Serious 4/4/2006 84 Female 7/6/2006 Other Health Professional France
Primary
Concomitant
Interacting
Somnolence Other Serious 1/1/2006 61 Male 209 lb 6/28/2006 United States
Primary
Concomitant
Hypoglycaemic Coma Life Threatening 6/2/2006 74 Male 7/10/2006 Pharmacist Japan
Primary
Secondary
Concomitant
Prothrombin Time Prolonged Other Serious 5/8/2006 83 Female 135 lb 5/8/2006 Pharmacist United States
Primary
Concomitant
Nervous System Disorder Other Serious 58 Female 176 lb 7/14/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Rheumatoid Arthritis Other Serious 2/22/2006 69 Male 7/11/2006 Pharmacist Canada
Primary
Concomitant
Rheumatoid Arthritis Other Serious 2/22/2006 69 Male 7/11/2006 Pharmacist Canada
Primary
Concomitant
Renal Impairment Other Serious 6/1/2006 44 Male 194 lb 7/10/2006 Physician Japan
Primary
Concomitant
Pulmonary Hypertension Hospitalization 7/14/2005 41 Female 143 lb 7/13/2006 Physician Japan
Primary
Concomitant
Ventricular Tachycardia Hospitalization 3/31/2006 74 223 lb 6/28/2006 Pharmacist United States
Primary
Secondary
Concomitant
Therapeutic Response Unexpected With Drug Substitution Other Serious 6/29/2006 91 Male 7/12/2006 United States
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Life Threatening 5/19/2006 81 Male 110 lb 7/14/2006 Pharmacist United States
Primary
Concomitant
Rheumatoid Arthritis Other Serious 2/22/2006 69 Male 7/14/2006 Pharmacist Canada
Primary
Concomitant
Ventricular Tachycardia Life Threatening 11/17/2005 78 Female 7/21/2006 Physician Japan
Primary
Secondary
Concomitant
Post Procedural Haemorrhage Hospitalization 5/26/2006 74 Male Pharmacist United States
Primary
Concomitant
Renal Impairment Other Serious 6/1/2006 44 Male 194 lb 7/20/2006 Physician Japan
Primary
Concomitant
Ventricular Tachycardia Hospitalization 12/1/2003 74 Male 7/26/2006 Physician Japan
Primary
Secondary
Concomitant
Renal Impairment Disability 4/7/2006 77 Male 128 lb 7/21/2006 Physician Japan
Primary
Concomitant
Pain In Extremity Other Serious 5/1/2005 75 Male 175 lb 7/21/2006 United States
Primary
Concomitant
Treatment Noncompliance Death 3/28/2005 68 Male 163 lb 7/25/2006 Pharmacist United States
Primary
Concomitant
Ventricular Tachycardia Other Serious 11/17/2005 Female 7/28/2006 Physician Japan
Primary
Secondary
Concomitant
Interacting
Diarrhoea Hospitalization 10/7/2004 51 Female 7/24/2006 Physician Japan
Primary
Concomitant
Wound Haemorrhage Hospitalization 3/31/2006 74 223 lb 6/28/2006 Pharmacist United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 74 Male 7/21/2006 Other Health Professional Denmark
Primary
Concomitant
Blood Glucose Increased 1/1/2005 68 Male 187 lb 8/1/2006 Consumer United States
Primary
Concomitant
International Normalised Ratio Decreased 5/16/2006 70 Male 194 lb 8/1/2006 Consumer United States
Primary
Concomitant
White Blood Cell Count Increased Death 2/16/2006 70 Female 7/27/2006 Physician Japan
Primary
Secondary
Concomitant
Vomiting Hospitalization 74 Male 7/31/2006 Other Health Professional Denmark
Primary
Secondary
Concomitant
Supraventricular Tachycardia Hospitalization 7/10/2006 Male 153 lb 8/8/2006 Other Health Professional Australia
Primary
Secondary
Concomitant
Renal Impairment Other Serious 6/1/2006 44 Male 194 lb 8/2/2006 Physician Japan
Primary
Concomitant
Restless Legs Syndrome Other Serious 6/29/2006 91 Male 8/3/2006 United States
Primary
Concomitant
Medication Residue Other Serious 1/1/2002 72 Female 128 lb 8/4/2006 United States
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 2/1/2006 74 Male 218 lb 7/5/2006 United States
Primary
Concomitant
Prothrombin Time Prolonged Hospitalization 6/1/2006 69 Male 8/10/2006 Physician Japan
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 74 Male 8/17/2006 Consumer France
Primary
Concomitant
International Normalised Ratio Increased Other Serious 78 Female 7/11/2006 United States
Primary
Secondary
Concomitant
Pharmaceutical Product Complaint 1/1/2002 72 Female 128 lb 8/14/2006 United States
Primary
Concomitant
Weight Decreased 4/1/2006 64 Male 217 lb 7/19/2006 Consumer United States
Primary
Concomitant
Ulcer Hospitalization 8/30/2006 69 Male 185 lb 9/1/2006 Pharmacist United States
Primary
Secondary
Concomitant
Ill-defined Disorder 3/14/2006 75 Male 9/6/2006 Consumer United States
Primary
Concomitant
Supraventricular Tachycardia Hospitalization 7/8/2006 Male 153 lb 9/7/2006 Other Health Professional Australia
Primary
Secondary
Concomitant
Vomiting 1/1/2005 72 Female 148 lb 7/25/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 7/8/2006 Male 153 lb 9/8/2006 Other Health Professional Australia
Primary
Secondary
Concomitant
Cough Life Threatening 4/10/2005 38 Male 9/11/2006 Physician Japan
Primary
Secondary
Concomitant
Liver Disorder Life Threatening 11/14/2005 48 Male 161 lb 9/11/2006 Physician Japan
Primary
Secondary
Concomitant
Thrombophlebitis Hospitalization 8/18/2005 65 Female 9/19/2006 Consumer Italy
Primary
Concomitant
Rectal Haemorrhage Other Serious 1/18/2006 78 Male 9/13/2006 Other Health Professional United States
Primary
Concomitant
Peptic Ulcer Hospitalization 6/1/2006 57 Male 262 lb 8/30/2006 Pharmacist United States
Primary
Secondary
Concomitant
International Normalised Ratio Abnormal Life Threatening 6/4/2006 89 Male 155 lb 6/5/2006 Pharmacist United States
Primary
Concomitant
Tremor Hospitalization 1/16/2006 57 Male 206 lb 5/4/2006 United States
Primary
Secondary
Concomitant
International Normalised Ratio Increased Hospitalization 4/25/2006 Male 203 lb 4/26/2006 Pharmacist United States
Primary
Concomitant
Platelet Count Decreased Hospitalization 9/7/2006 74 Male 121 lb 9/21/2006 Japan
Primary
Concomitant
Serotonin Syndrome Other Serious 9/23/2006 38 Female 225 lb 9/28/2006 Pharmacist United States
Primary
Concomitant
Sudden Death Death 4/5/2005 Male 9/28/2006 Physician United Kingdom
Primary
Secondary
International Normalised Ratio Increased Hospitalization 9/27/2006 62 Male 230 lb 9/29/2006 Pharmacist United States
Primary
Concomitant
Hypophosphataemia Hospitalization 7/5/2006 69 Male 10/5/2006 United Kingdom
Primary
Concomitant
Ventricular Tachycardia Hospitalization 5/18/2005 70 Female 10/6/2006 Physician Japan
Primary
Secondary
Concomitant
Renal Impairment Other Serious 10/1/2005 92 Female 10/6/2006 Pharmacist Japan
Primary
Concomitant
Surgery Other Serious 11/27/2003 65 Male 152 lb 10/7/2006 Physician Japan
Primary
Secondary
Concomitant
Cerebrovascular Accident Hospitalization 6/18/2006 87 Male 179 lb 10/4/2006 Pharmacist United States
Primary
Concomitant
Treatment Noncompliance Hospitalization 7/25/2006 55 Male 196 lb 10/4/2006 Pharmacist United States
Primary
Concomitant
Platelet Count Decreased Hospitalization 9/7/2006 74 Male 121 lb 10/3/2006 Physician Japan
Primary
Concomitant
Liver Disorder Hospitalization 7/6/2006 82 Female 86 lb 10/9/2006 Physician Japan
Primary
Concomitant
Ventricular Fibrillation Hospitalization 9/1/2004 75 Male 10/10/2006 Physician Japan
Primary
Concomitant
Neutropenia Other Serious 74 Female 175 lb 10/10/2006 Physician
Primary
Secondary
Concomitant
Neutropenia Other Serious 74 Female 10/16/2006 Physician
Primary
Secondary
Concomitant
Liver Disorder Hospitalization 7/6/2006 82 Female 86 lb 10/18/2006 Physician Japan
Primary
Secondary
Concomitant
Thrombosis Life Threatening 6/28/2006 78 Male 230 lb 8/25/2006 Pharmacist United States
Primary
Concomitant
Nodal Arrhythmia Death 7/26/2006 86 Female 8/25/2006 Pharmacist United States
Primary
Concomitant
Urinary Incontinence Other Serious 4/4/2006 84 Female 134 lb 10/20/2006 Other Health Professional France
Primary
Concomitant
Interacting
Prothrombin Time Prolonged Other Serious 6/1/2006 69 Male 10/13/2006 Physician Japan
Primary
Secondary
Concomitant
Vaginal Haemorrhage Hospitalization 8/14/2006 77 Female 207 lb 10/16/2006 Other Health Professional United Kingdom
Primary
Concomitant
Neutropenia Other Serious 74 Female 10/23/2006 Physician
Primary
Secondary
Concomitant
Neutropenia Other Serious 74 Female 175 lb 10/18/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Loss Of Consciousness Hospitalization 6/29/2005 63 Male 10/25/2006 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 7/6/2006 82 Female 86 lb 10/26/2006 Physician Japan
Primary
Secondary
Concomitant
Vaginal Haemorrhage Hospitalization 8/14/2006 77 Female 10/19/2006 Other Health Professional United Kingdom
Primary
Concomitant
Hypoparathyroidism Other Serious 80 Male 10/27/2006 Other Health Professional Australia
Primary
Concomitant
Restlessness Hospitalization 9/20/2006 71 Male 95 lb 10/30/2006 Physician Japan
Primary
Concomitant
Hypoparathyroidism Other Serious 80 Male 11/3/2006 Other Health Professional Australia
Primary
Concomitant
Liver Disorder Life Threatening 11/14/2005 48 Male 161 lb 11/3/2006 Physician Japan
Primary
Secondary
Concomitant
Myelofibrosis Other Serious 1/1/2006 73 Male 237 lb 10/27/2006 Other Health Professional United States
Primary
Concomitant
Serotonin Syndrome Other Serious 9/23/2006 38 Female 11/3/2006 Physician United States
Primary
Concomitant
Somnolence Hospitalization 9/20/2006 71 Male 95 lb 11/13/2006 Physician Japan
Primary
Concomitant
Pulmonary Embolism Hospitalization 2/10/2006 43 Male 11/8/2006 Consumer Canada
Primary
Concomitant
Thrombocytopenia Other Serious 62 Male 11/17/2006 Consumer United Kingdom
Primary
Secondary
Surgery Other Serious 11/27/2003 65 Male 152 lb 11/18/2006 Physician Japan
Primary
Secondary
Concomitant
Renal Impairment Other Serious 10/1/2005 92 Female 11/20/2006 Pharmacist Japan
Primary
Concomitant
Ventricular Tachycardia Hospitalization 1/6/2005 57 Male 11/8/2006 Japan
Primary
Concomitant
Platelet Count Decreased Hospitalization 9/7/2006 74 Male 121 lb 11/9/2006 Physician Japan
Primary
Concomitant
Pain In Extremity Other Serious 75 Male 175 lb 11/10/2006 Physician United States
Primary
Secondary
Concomitant
Hypoglycaemia Other Serious 8/25/2006 Female 254 lb 10/30/2006 United Kingdom
Primary
Concomitant
Loss Of Consciousness Other Serious 10/18/2006 81 Female 11/29/2006 Physician Japan
Primary
Concomitant
Renal Impairment Disability 4/7/2006 77 Male 128 lb 11/20/2006 Physician Japan
Primary
Concomitant
Myocardial Infarction Death 5/2/2006 71 Female 250 lb 11/17/2006 United States
Primary
Concomitant
Loss Of Consciousness Other Serious 10/18/2006 81 Female 12/1/2006 Physician Japan
Primary
Concomitant
Treatment Noncompliance Hospitalization 9/1/2005 75 Male 11/22/2006 Physician Japan
Primary
Concomitant
International Normalised Ratio Increased Hospitalization 11/27/2006 59 Male 223 lb 11/30/2006 Pharmacist United States
Primary
Concomitant
Right Ventricular Failure Hospitalization 10/7/2004 51 Female 11/30/2006 Physician Japan
Primary
Concomitant
Pulmonary Hypertension Hospitalization 7/14/2005 41 Female 143 lb 11/30/2006 Physician Japan
Primary
Concomitant
Right Ventricular Failure Death 10/26/2004 45 Female 116 lb 11/30/2006 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 10/23/2006 84 Male 11/30/2006 Japan
Primary
Concomitant
Melaena Hospitalization 11/16/2006 77 Male 139 lb 12/12/2006 Physician Japan
Primary
Concomitant
Staphylococcal Infection Other Serious 9/23/2006 38 Female 219 lb 11/30/2006 Physician United States
Primary
Concomitant
Inappropriate Antidiuretic Hormone Secretion Hospitalization 10/15/2006 81 Female 12/14/2006 Physician Japan
Primary
Concomitant
Chest Pain Hospitalization 1/9/2006 75 Female 108 lb 12/16/2006 Physician Japan
Primary
Concomitant
Pyrexia Other Serious 1/1/2006 73 Male 230 lb 12/7/2006 Physician United States
Primary
Concomitant
Cough Life Threatening 4/10/2005 38 Male 12/19/2006 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 11/27/2005 68 Male 212 lb 12/19/2006 Physician United Kingdom
Primary
Concomitant

Drug Data