Allopurinol combined with Voriconazole

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Rash Hospitalization 12/13/2005 27 Female 136 lb 1/10/2006 Physician United States
Primary
Secondary
Concomitant
Pyrexia Life Threatening 1/17/2005 Male 207 lb 2/8/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Rash Hospitalization 12/13/2005 27 Female 136 lb 2/1/2006 Physician United States
Primary
Secondary
Concomitant
Platelet Count Decreased Hospitalization 10/30/2004 29 Female 121 lb 2/18/2006 Other Health Professional United States
Primary
Concomitant
Chest X-ray Abnormal Hospitalization 7/13/2005 70 Male 2/27/2006 United Kingdom
Primary
Concomitant
Obstruction Hospitalization 74 Male 3/16/2006 Pharmacist United States
Primary
Secondary
Concomitant
Lymphocyte Count Decreased Hospitalization 10/30/2004 29 Female 121 lb 4/1/2006 United States
Primary
Concomitant
Rash Hospitalization 12/13/2005 27 Female 136 lb 4/3/2006 Other Health Professional United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Death 7/30/2005 66 Male 203 lb 5/3/2006 Other Health Professional Hungary
Primary
Secondary
Concomitant
Prothrombin Time Prolonged Life Threatening 3/8/2006 73 Male 5/24/2006 Japan
Primary
Concomitant
White Blood Cell Count Increased Life Threatening 3/8/2006 73 Male 7/11/2006 Japan
Primary
Concomitant
Prothrombin Time Prolonged Life Threatening 3/8/2006 73 Male 7/18/2006 Japan
Primary
Concomitant
Tumour Lysis Syndrome Hospitalization 7/10/2006 Male 140 lb 7/27/2006 Other Health Professional United States
Primary
Concomitant
Renal Failure Other Serious 6/12/2006 62 Male 7/27/2006 Other Health Professional United States
Primary
Concomitant
Staphylococcal Infection Hospitalization 2/25/2006 59 Male 160 lb 8/12/2006 Physician United States
Primary
Secondary
Concomitant
Renal Failure Other Serious 6/12/2006 62 Male 9/1/2006 Physician United States
Primary
Concomitant
Vomiting Hospitalization 5/1/2006 33 Female 9/1/2006 Physician United States
Primary
Secondary
Concomitant
Tachycardia Hospitalization 8/24/2006 58 Male 9/26/2006 Physician United States
Primary
Secondary
Concomitant
Vomiting 2/8/2006 36 Male Physician United States
Primary
Concomitant
Ureteric Obstruction Hospitalization 1/31/2007 39 Male 2/26/2007 Other Health Professional United States
Primary
Concomitant
Tachycardia Hospitalization 2/7/2007 40 Male 3/27/2007 Other Health Professional United States
Primary
Concomitant
Stomatitis Other Serious 9/13/2006 51 Male 3/29/2007 Japan
Primary
Secondary
Concomitant
Stomatitis Other Serious 9/13/2006 51 Male 4/9/2007 Japan
Primary
Secondary
Concomitant
Tachycardia Hospitalization 2/7/2007 40 Male 4/5/2007 Physician United States
Primary
Concomitant
Stomatitis Other Serious 9/13/2006 51 Male 4/25/2007 United States
Primary
Secondary
Concomitant
Virus Urine Test Positive Hospitalization 1/31/2007 40 Male 223 lb 4/30/2007 Physician United States
Primary
Secondary
Concomitant
Heart Rate Irregular Other Serious 5/29/2007 62 Male 174 lb 6/26/2007 Physician United Kingdom
Primary
Concomitant
Haemolysis Hospitalization 5/15/2005 Female 123 lb 7/3/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Hospitalization 10/22/2006 11 Female 75 lb 7/2/2007 Physician United States
Primary
Secondary
Concomitant
Immunosuppressant Drug Level Increased Hospitalization 3/1/2005 18 Male 115 lb 7/11/2007 Physician Germany
Primary
Concomitant
Interacting
Haemoptysis Other Serious 7/27/2005 Male 203 lb 7/13/2007 Consumer Hungary
Primary
Secondary
Concomitant
Thrombosis Required Intervention 6/17/2007 35 Male 88 lb 6/20/2007 Pharmacist United States
Primary
Secondary
Concomitant
Vision Blurred Hospitalization 6/8/2007 Male 107 lb 6/11/2007 Pharmacist United States
Primary
Concomitant
Jaundice Life Threatening 8/9/2007 Male 117 lb 9/11/2007 Physician Japan
Primary
Secondary
Concomitant
Ventricular Dysfunction Other Serious 8/13/2007 10 Female 75 lb 9/11/2007 Pharmacist United States
Primary
Concomitant
Tumour Lysis Syndrome Required Intervention 8/4/2007 10 Female 75 lb 9/12/2007 Pharmacist United States
Primary
Concomitant
Haemolysis Hospitalization 5/15/2005 Female 123 lb 9/26/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Upper Gastrointestinal Haemorrhage Hospitalization 6/21/2007 Male 142 lb 9/21/2007 Other Health Professional United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 51 Male 10/3/2007 Physician Brazil
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 51 Male 10/22/2007 Physician Brazil
Primary
Concomitant
Venoocclusive Disease Other Serious 9/19/2007 Female 137 lb 11/2/2007 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Traumatic Intracranial Haemorrhage Life Threatening 6/30/2007 63 Male 10/4/2007 Physician United States
Primary
Secondary
Concomitant
Staphylococcal Bacteraemia Life Threatening 10/7/2007 14 Male 203 lb 11/8/2007 Physician United States
Primary
Secondary
Concomitant
Venoocclusive Disease Life Threatening 9/19/2007 19 Female 11/19/2007 Consumer United Kingdom
Primary
Secondary
Dilatation Intrahepatic Duct Acquired Life Threatening 9/19/2007 19 Female 11/21/2007 United Kingdom
Primary
Secondary
Venoocclusive Disease Other Serious 9/19/2007 19 Female 11/21/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Venoocclusive Disease Other Serious 9/19/2007 19 Female 11/26/2007 Other Health Professional United Kingdom
Primary
Secondary
Venoocclusive Disease Other Serious 9/19/2007 19 Female 11/27/2007 Other Health Professional United Kingdom
Primary
Secondary
Dilatation Intrahepatic Duct Acquired Life Threatening 9/19/2007 19 Female 11/26/2007 United Kingdom
Primary
Secondary
Venoocclusive Disease Other Serious 19 Female 11/27/2007 Other Health Professional United Kingdom
Primary
Secondary
White Blood Cell Count Decreased Life Threatening 11/2/2007 15 Female 208 lb 11/19/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Tachycardia Life Threatening 9/28/2007 21 Female 150 lb 11/21/2007 Consumer United States
Primary
Secondary
Concomitant
Venoocclusive Disease Other Serious 19 Female 11/30/2007 Pharmacist United Kingdom
Primary
Concomitant
Venoocclusive Disease Life Threatening 11/5/2007 15 Female 208 lb 12/3/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Unresponsive To Stimuli Life Threatening 9/28/2007 21 Female 150 lb 12/3/2007 Physician United States
Primary
Secondary
Concomitant
Venoocclusive Disease Other Serious 9/19/2007 Female 137 lb 12/26/2007 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Hypokalaemia Life Threatening 2/4/2008 Female 3/17/2008 Physician United Kingdom
Primary
Concomitant
Febrile Neutropenia Hospitalization 5/19/2007 Male 3/28/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Failure Life Threatening 2/4/2008 Female 4/17/2008 Physician United Kingdom
Primary
Concomitant
Death Death 4/26/2008 56 Male 208 lb 5/19/2008 Other Health Professional United Kingdom
Primary
Concomitant
Renal Failure Life Threatening 2/4/2008 Female 5/27/2008 Physician United Kingdom
Primary
Concomitant
Toxic Epidermal Necrolysis Death 4/18/2008 58 Female 5/16/2008 Pharmacist United States
Primary
Secondary
Concomitant
Drug Rash With Eosinophilia And Systemic Symptoms Other Serious 53 Female 6/19/2008 Other Health Professional Japan
Primary
Secondary
Nephropathy Toxic Hospitalization 12/7/2007 58 Male 178 lb 6/22/2008 Pharmacist United States
Primary
Secondary
Concomitant
Nephropathy Toxic Hospitalization 12/4/2007 69 Male 183 lb 6/22/2008 Pharmacist United States
Primary
Secondary
Concomitant
Nephropathy Toxic Hospitalization 12/5/2007 43 Male 197 lb 6/22/2008 Pharmacist United States
Primary
Secondary
Concomitant
Diarrhoea Other Serious 6/1/2008 Female 106 lb 7/16/2008 Physician Denmark
Primary
Concomitant
Hepatic Function Abnormal Other Serious 12/1/2005 56 Male 128 lb 8/15/2008 Japan
Primary
Secondary
Concomitant
Drug Rash With Eosinophilia And Systemic Symptoms Other Serious 53 Female 8/18/2008 Other Health Professional Japan
Primary
Secondary
Diarrhoea Other Serious 6/1/2008 Female 106 lb 9/8/2008 Physician Denmark
Primary
Concomitant
Renal Failure Acute Other Serious 7/18/2008 75 Male 226 lb 9/9/2008 United States
Primary
Secondary
Concomitant
Wegener's Granulomatosis Hospitalization 12/18/2007 51 Male 10/29/2008 Other Health Professional France
Primary
Secondary
Concomitant
Wegener's Granulomatosis Hospitalization 1/19/2008 51 Male 10/31/2008 Other Health Professional France
Primary
Secondary
Concomitant
Respiratory Failure Life Threatening 6/24/2008 Female 163 lb 6/29/2008 Pharmacist United States
Primary
Concomitant
Renal Failure Acute Other Serious 7/18/2008 75 Male 225 lb 11/18/2008 United States
Primary
Secondary
Concomitant
Urinary Retention Hospitalization 7/28/2008 65 Male 207 lb 12/1/2008 United States
Primary
Secondary
Concomitant
Weight Increased Death 12/5/2008 69 Female 12/18/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Hallucinations, Mixed Other Serious 12/7/2008 Female 93 lb 1/5/2009 Physician Thailand
Primary
Secondary
Concomitant
Hallucinations, Mixed Other Serious 12/7/2008 1/21/2009 Physician Thailand
Primary
Secondary
Concomitant
Venoocclusive Disease Other Serious 9/19/2007 19 Female 2/23/2009 Other Health Professional United Kingdom
Primary
Secondary
Rash Required Intervention 12/19/2008 69 Male 190 lb 1/6/2009 Pharmacist United States
Primary
Concomitant
Renal Failure Hospitalization 5/7/2009 Female 187 lb 5/20/2009 Physician Germany
Primary
Concomitant
Sepsis Life Threatening 2/20/2009 71 5/29/2009 Germany
Primary
Secondary
Concomitant
Leukaemia Death Female 9/3/2009 Lawyer United States
Primary
Concomitant
White Blood Cell Count Decreased Life Threatening 3/30/2009 59 Male 9/16/2009 Physician Japan
Primary
Concomitant
Small Intestinal Obstruction Hospitalization 7/24/2009 60 Male 9/24/2009 Physician United States
Primary
Secondary
Concomitant
Somnolence Life Threatening 3/30/2009 59 Male 10/7/2009 Physician Japan
Primary
Concomitant
Urinary Hesitation Hospitalization 7/28/2008 65 Male 207 lb 10/6/2009 United States
Primary
Secondary
Concomitant
Refusal Of Treatment By Patient Other Serious 11/27/2007 49 Male 189 lb 10/5/2009 Physician United States
Primary
Secondary
Concomitant
Somnolence Hospitalization 3/30/2009 59 Male 10/15/2009 Physician Japan
Primary
Concomitant
Pneumonia Other Serious 1/1/2007 72 Female 10/21/2009 Lawyer United States
Primary
Concomitant
Unresponsive To Stimuli Hospitalization 7/24/2009 60 Male 223 lb 10/21/2009 Physician United States
Primary
Secondary
Concomitant
Renal Failure Other Serious 9/23/2009 Male 255 lb 10/28/2009 United States
Primary
Secondary
Concomitant
Urticaria Other Serious 1/1/2008 Male 11/2/2009 Physician United States
Primary
Concomitant
Interacting
Unresponsive To Stimuli Other Serious 7/24/2009 60 Male 223 lb 11/5/2009 Physician United States
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 7/18/2008 75 Male 225 lb 11/9/2009 Other Health Professional United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 9/23/2009 Male 255 lb 12/2/2009 United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 9/23/2009 Male 255 lb 12/2/2009 United States
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 2/19/2009 7 Female 63 lb 11/30/2009 Physician United States
Primary
Secondary
Concomitant
Visual Impairment Hospitalization 9/25/2009 63 Female 10/10/2009 United States
Primary
Concomitant
Pneumonia Other Serious 1/1/2007 72 Female 1/27/2010 Lawyer United States
Primary
Concomitant
Somnolence Hospitalization 3/30/2009 59 Male 1/29/2010 Physician Japan
Primary
Concomitant
Thrombocytopenia Other Serious 12/29/2009 Male 2/22/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Life Threatening 11/8/2007 20 Male 118 lb 3/12/2010 Physician United States
Primary
Secondary
Concomitant
Gamma-glutamyltransferase Increased Other Serious 3/14/2010 7 Male 45 lb 4/1/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 12/29/2009 75 Male 4/12/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 12/29/2009 75 Male 5/4/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Tumour Lysis Syndrome Other Serious 5/17/2010 27 Male 159 lb 6/21/2010 Physician Canada
Primary
Concomitant
Syncope Other Serious 10/6/2007 50 Male 194 lb 6/30/2010 Lawyer United States
Primary
Concomitant
Wound Infection Staphylococcal Life Threatening 11/8/2007 20 Male 118 lb 6/30/2010 Physician United States
Primary
Secondary
Concomitant
Febrile Neutropenia Life Threatening 5/3/2010 57 Male 7/7/2010 Physician Italy
Primary
Concomitant
Thrombocytopenia Other Serious 12/29/2009 75 Male 7/7/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Scedosporium Infection Other Serious 11/16/2009 35 Male 132 lb 7/7/2010 Physician Japan
Primary
Secondary
Concomitant
Scedosporium Infection Other Serious 4/25/2009 34 Male 132 lb 7/20/2010 Physician Japan
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 12/29/2009 75 Male 7/29/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Tumour Lysis Syndrome Other Serious 5/17/2010 27 Male 159 lb 8/3/2010 Physician Canada
Primary
Concomitant
Tumour Lysis Syndrome Other Serious 5/17/2010 27 Male 159 lb 8/4/2010 Physician Canada
Primary
Concomitant
Tumour Lysis Syndrome Other Serious 5/17/2010 27 Male 159 lb 8/11/2010 Physician Canada
Primary
Concomitant
Lipase Increased Other Serious 8/3/2010 13 Female 99 lb 8/20/2010 Physician United States
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Life Threatening 11/8/2007 20 Male 118 lb 8/18/2010 Physician United States
Primary
Secondary
Concomitant
Tachycardia Other Serious 9/20/2007 50 Male 194 lb 8/27/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Life Threatening Female 8/30/2010 Pharmacist United Kingdom
Primary
Secondary
Venoocclusive Disease Other Serious 9/19/2007 19 Female 9/7/2010 Other Health Professional United Kingdom
Primary
Secondary
Venoocclusive Liver Disease Other Serious 19 Female 9/7/2010 Pharmacist United Kingdom
Primary
Secondary
Lipase Increased Other Serious 8/3/2010 13 Female 99 lb 9/8/2010 Physician United States
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Life Threatening 9/19/2007 19 Female 9/9/2010 Consumer United Kingdom
Primary
Secondary
Venoocclusive Liver Disease Life Threatening Female 9/9/2010 Pharmacist United Kingdom
Primary
Secondary
Venoocclusive Liver Disease Other Serious 9/19/2007 19 Female 9/10/2010 Other Health Professional United Kingdom
Primary
Secondary
Venoocclusive Liver Disease Other Serious 19 Female 9/10/2010 Pharmacist United Kingdom
Primary
Secondary
Venoocclusive Liver Disease Life Threatening 19 Female 9/10/2010 Consumer United Kingdom
Primary
Secondary
Venoocclusive Disease Other Serious 9/19/2007 19 Female 9/10/2010 Other Health Professional United Kingdom
Primary
Secondary
Dilatation Intrahepatic Duct Acquired Other Serious 1/1/2007 19 Female 9/10/2010 Other Health Professional United Kingdom
Primary
Secondary
Venoocclusive Liver Disease Life Threatening 9/19/2007 19 Female 9/10/2010 Other Health Professional United Kingdom
Primary
Secondary
Dilatation Intrahepatic Duct Acquired Other Serious 1/1/2007 19 Female 9/10/2010 Other Health Professional United Kingdom
Primary
Secondary
Venoocclusive Liver Disease Life Threatening 9/19/2007 19 Female 9/10/2010 Other Health Professional United Kingdom
Primary
Secondary
Venoocclusive Liver Disease Other Serious 9/19/2007 19 Female 9/13/2010 Pharmacist United Kingdom
Primary
Secondary
Venoocclusive Disease Other Serious 9/19/2007 19 Female 9/14/2010 Other Health Professional United Kingdom
Primary
Secondary
Venoocclusive Liver Disease Other Serious 19 Female 9/14/2010 Other Health Professional United Kingdom
Primary
Secondary
Venoocclusive Liver Disease Life Threatening 22 Female 9/9/2010 Other Health Professional United Kingdom
Primary
Secondary
Venoocclusive Liver Disease Life Threatening 19 Female 9/15/2010 Other Health Professional United Kingdom
Primary
Secondary
Venoocclusive Liver Disease Life Threatening 22 Female 9/16/2010 Other Health Professional United Kingdom
Primary
Secondary
Venoocclusive Liver Disease Other Serious 19 Female 9/10/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Other Serious 9/19/2007 19 Female 9/16/2010 Pharmacist United Kingdom
Primary
Secondary
Venoocclusive Liver Disease Other Serious 19 Female 9/9/2010 Consumer United Kingdom
Primary
Secondary
Venoocclusive Disease Other Serious 9/19/2007 19 Female 137 lb 9/17/2010 Pharmacist United Kingdom
Primary
Secondary
Venoocclusive Liver Disease Other Serious 9/20/2010 Other Health Professional United Kingdom
Primary
Secondary
Venoocclusive Liver Disease Other Serious 9/19/2007 19 Female 9/20/2010 Pharmacist United Kingdom
Primary
Secondary
Venoocclusive Liver Disease Life Threatening 19 Female 9/7/2010 United Kingdom
Primary
Secondary
Venoocclusive Disease Other Serious 9/19/2007 19 Female 9/21/2010 Other Health Professional United Kingdom
Primary
Secondary
Dilatation Intrahepatic Duct Acquired Other Serious 1/1/2007 19 Female 9/21/2010 Other Health Professional United Kingdom
Primary
Secondary

Drug Data