Allopurinol combined with Vincristine Sulfate

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Constipation Other Serious 12/6/2005 Male 156 lb 2/7/2006 United States
Primary
Secondary
Concomitant
Constipation Other Serious 12/5/2005 Male 156 lb 2/8/2006 United States
Primary
Secondary
Concomitant
Thrombosis Other Serious 3/21/2006 Male 161 lb 3/24/2006 United States
Primary
Secondary
Pneumonia Death 2/13/2006 Male 186 lb 2/15/2006 United States
Primary
Secondary
Thrombosis Hospitalization 6/21/2006 Male 183 lb 6/26/2006 United States
Primary
Secondary
Tachycardia Hospitalization 3/4/2006 Male 311 lb 8/11/2006 United States
Primary
Secondary
Urinary Tract Infection Hospitalization 3/7/2007 Male 282 lb 4/16/2007 United States
Primary
Secondary
Concomitant
Cardiac Failure Death 3/19/2007 52 Female 5/8/2007 Consumer Japan
Primary
Secondary
Concomitant
Tachycardia Hospitalization 5/5/2007 Female 132 lb 5/8/2007 United States
Primary
Secondary
Myelodysplastic Syndrome Other Serious 1/15/2007 59 Male 234 lb 5/24/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Septic Embolus Death 5/7/2007 Female 152 lb 6/15/2007 United States
Primary
Secondary
Osteoarthritis Hospitalization 6/22/2007 Female 229 lb 7/5/2007 United States
Primary
Secondary
Vomiting Other Serious 12/17/2007 69 Male 1/23/2008 Consumer United States
Primary
Secondary
Concomitant
Unresponsive To Stimuli Hospitalization 8/11/2006 Female 277 lb 1/31/2008 United States
Primary
Secondary
Concomitant
Visual Acuity Reduced Hospitalization 3/11/2004 Female 169 lb 2/20/2008 United States
Primary
Secondary
Sepsis Other Serious 3/31/2008 85 Male 4/10/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Pain In Jaw Other Serious 39 Female 4/11/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
No Adverse Event 39 Female 4/24/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Disorder Hospitalization 10/16/2001 Female 4/29/2008 Japan
Primary
Secondary
Concomitant
Renal Disorder Hospitalization 10/16/2001 Female 6/24/2008 Japan
Primary
Secondary
Concomitant
Calculus Urinary Other Serious 11 Male 6/25/2008 Other Health Professional Japan
Primary
Secondary
Calculus Urinary Other Serious 11 Male 6/30/2008 Other Health Professional Japan
Primary
Secondary
Sepsis Hospitalization 3/31/2008 85 Male 183 lb 7/17/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Oedema Hospitalization 9/13/2008 Male 167 lb 9/16/2008 United States
Primary
Secondary
Tooth Abscess Hospitalization 8/11/2006 Male 139 lb 10/22/2008 United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 11/4/2008 42 Male 209 lb 11/25/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 42 Male 238 lb 12/2/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Odynophagia Hospitalization 8/28/2008 43 Female 12/4/2008 Other Health Professional France
Primary
Secondary
Concomitant
Weight Decreased Other Serious 11/4/2008 42 Male 209 lb 12/18/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 11/4/2008 42 Male 238 lb 12/29/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Pharyngeal Oedema Hospitalization 12/27/2008 Male 183 lb 12/30/2008 United States
Primary
Secondary
Renal Failure Acute Hospitalization 1/18/2009 Male 172 lb 1/22/2009 United States
Primary
Secondary
White Blood Cell Count Decreased Other Serious 11/4/2008 42 Male 209 lb 2/25/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 11/4/2008 Male 210 lb 2/27/2009 Other Health Professional United States
Primary
Secondary
Concomitant
No Therapeutic Response Hospitalization 2/8/2009 Male 236 lb 2/23/2009 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 11/4/2008 42 Male 238 lb 3/6/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Stevens-johnson Syndrome Hospitalization 1/1/2004 45 Male 3/26/2009 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 12/29/2008 69 Male 5/14/2009 Physician United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 5/29/2009 Male 215 lb 6/1/2009 United States
Primary
Secondary
Concomitant
Ejection Fraction Decreased 8/5/2009 Male 218 lb 8/7/2009 United States
Primary
Secondary
Concomitant
Rectal Haemorrhage Hospitalization 7/14/2009 Male 214 lb 8/5/2009 United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 7/27/2009 79 Female 99 lb 10/6/2009 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 7/26/2009 69 Female 141 lb 10/12/2009 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 7/26/2009 69 Female 141 lb 10/15/2009 Physician Japan
Primary
Secondary
Concomitant
Ventricular Dysfunction Other Serious 7 Male 57 lb 10/28/2009 Other Health Professional Canada
Primary
Secondary
Concomitant
Neutropenia Other Serious 1/1/2009 58 Female 225 lb 11/2/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Therapeutic Response Decreased Other Serious 5/1/2009 Female 225 lb 11/6/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Application Site Cellulitis Hospitalization 11/8/2009 Male 171 lb 11/27/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Septic Shock Life Threatening 9/23/2009 63 Male 11/30/2009 Other Health Professional Italy
Primary
Secondary
Concomitant
Lower Respiratory Tract Infection Hospitalization 10/21/2009 Female 110 lb 12/1/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Pulmonary Oedema Hospitalization 11/7/2009 Female 158 lb 12/3/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Therapeutic Response Decreased Other Serious 5/1/2009 Female 225 lb 12/14/2009 Other Health Professional United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 7/27/2009 79 Female 99 lb 12/30/2009 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 2/9/2009 54 Male 1/5/2010 Physician Japan
Primary
Secondary
Concomitant
Pyrexia Hospitalization 1/8/2010 Female 179 lb 1/11/2010 United States
Primary
Secondary
Pulmonary Oedema Hospitalization 11/7/2009 Female 158 lb 1/19/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Pleural Effusion Life Threatening 9/1/2009 Female 145 lb 1/19/2010 Consumer United States
Primary
Secondary
Concomitant
Post Lumbar Puncture Syndrome Hospitalization 1/11/2010 Female 133 lb 1/18/2010 United States
Primary
Secondary
Vomiting Other Serious 3 Female 29 lb 1/20/2010 Other Health Professional Canada
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 7/27/2009 79 Female 99 lb 2/22/2010 Physician Japan
Primary
Secondary
Concomitant
Renal Failure Acute Death 11/17/2009 61 Male 2/25/2010 Other Health Professional Italy
Primary
Secondary
Concomitant
Hyperglycaemia 2/16/2010 Male 71 lb 2/25/2010 United States
Primary
Secondary
Concomitant
Ventricular Tachycardia Hospitalization 3/1/2010 Male 190 lb 3/2/2010 United States
Primary
Secondary
Urine Chloride Decreased Other Serious 16 Male 123 lb 3/10/2010 Other Health Professional Canada
Primary
Concomitant
Pneumonia Fungal Hospitalization 3/17/2010 Male 145 lb 3/25/2010 United States
Primary
Secondary
White Blood Cell Count Decreased Other Serious 2/9/2009 54 Male 4/8/2010 Physician Japan
Primary
Secondary
Concomitant
Stomatitis Hospitalization 12/14/2009 60 Male 4/8/2010 Other Health Professional Italy
Primary
Secondary
Concomitant
Neutropenia Hospitalization 2/26/2010 69 Male 4/20/2010 Other Health Professional Italy
Primary
Secondary
Concomitant
Thrombosis Hospitalization 10/29/2009 62 Male 171 lb 4/26/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 2/1/2010 74 Male 4/29/2010 Other Health Professional Italy
Primary
Secondary
Concomitant
Headache Hospitalization 3/26/2010 25 Female 4/29/2010 Other Health Professional France
Primary
Secondary
Concomitant
Neutropenia Hospitalization 2/26/2010 69 Male 4/29/2010 Other Health Professional Italy
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Death 6/7/2007 2 Female 29 lb 4/30/2010 Physician Japan
Primary
Concomitant
Interacting
Bronchopneumonia Hospitalization 12/2/2009 69 Male 5/4/2010 Other Health Professional Italy
Primary
Secondary
Concomitant
Idiosyncratic Drug Reaction Death 12/18/2008 81 Female 132 lb 5/18/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vomiting 5/19/2010 20 Male 169 lb 5/20/2010 United States
Primary
Secondary
Stomatitis Hospitalization 12/14/2009 60 Male 5/27/2010 Other Health Professional Italy
Primary
Secondary
Concomitant
Neutropenia Hospitalization 2/26/2010 69 Male 6/8/2010 Other Health Professional Italy
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 1/29/2010 74 Male 6/10/2010 Other Health Professional Italy
Primary
Secondary
Concomitant
Sepsis Hospitalization 3/31/2008 85 Male 183 lb 6/14/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 1/29/2010 74 Male 6/17/2010 Other Health Professional Italy
Primary
Secondary
Concomitant
Bronchopneumonia Hospitalization 12/2/2009 69 Male 6/18/2010 Other Health Professional Italy
Primary
Secondary
Concomitant
Weight Decreased Other Serious 11/4/2008 42 Male 209 lb 6/25/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Rash Other Serious 2/25/2009 55 Male 6/28/2010 Physician Japan
Primary
Secondary
Concomitant
Neuropathy Peripheral Other Serious 2 Male 33 lb 8/2/2010 Other Health Professional Canada
Primary
Concomitant
Idiosyncratic Drug Reaction Death 12/18/2008 81 Female 8/25/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Hyperglycaemia Hospitalization 8/5/2010 36 Male 163 lb 8/27/2010 United States
Primary
Secondary
Pancreatitis Acute Hospitalization 9/4/2010 81 Female 10/8/2010 Other Health Professional France
Primary
Secondary
Concomitant
Hyperglycaemia Hospitalization 8/7/2010 13 Male 130 lb 10/18/2010 United States
Primary
Secondary
Concomitant
Pleural Effusion Hospitalization 10/28/2010 Other Health Professional Australia
Primary
Concomitant
Blood Bilirubin Abnormal 9/5/2010 13 Male 130 lb 10/22/2010 United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 4/9/2010 11/1/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Neutropenia Hospitalization 4/9/2010 11/1/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Progressive Multifocal Leukoencephalopathy Hospitalization 5/1/2010 72 Female 11/11/2010 Other Health Professional Sweden
Primary
Secondary
Concomitant
Orthopnoea Hospitalization 11/3/2010 65 Female 11/15/2010 Physician Italy
Primary
Secondary
Concomitant
Pneumothorax Hospitalization 11/5/2010 39 Male 223 lb 11/16/2010 United States
Primary
Secondary
Interstitial Lung Disease Hospitalization 1/1/2010 80 Male 132 lb 11/29/2010 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Interstitial Lung Disease Hospitalization 1/1/2010 80 Male 132 lb 12/2/2010 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Orthopnoea Hospitalization 11/3/2010 65 Female 12/2/2010 Physician Italy
Primary
Secondary
Concomitant
Progressive Multifocal Leukoencephalopathy Hospitalization 5/1/2010 72 Female 12/8/2010 Other Health Professional Sweden
Primary
Secondary
Concomitant
Vomiting Hospitalization 5 Male 12/23/2010 Physician Turkey
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 10 Male 12/23/2010 Physician Turkey
Primary
Secondary
Concomitant
Hepatitis Acute Hospitalization 11/24/2010 63 Male 187 lb 2/3/2011 Consumer United States
Primary
Secondary
Concomitant
Pneumonia Life Threatening 2/9/2009 54 Male 2/3/2011 Physician Japan
Primary
Secondary
Concomitant
Headache Hospitalization 2/13/2011 22 Male 169 lb 3/8/2011 United States
Primary
Secondary
Renal Failure Acute Other Serious 9/17/2002 43 Female 204 lb 3/16/2011 Physician United States
Primary
Secondary
Concomitant
Hypoaesthesia Other Serious 7/2/2003 55 Male 187 lb 3/17/2011 United States
Primary
Secondary
Concomitant
Orthostatic Hypotension Hospitalization 11/9/2010 24 Male 167 lb 3/16/2011 United States
Primary
Secondary
Gamma-glutamyltransferase Increased Other Serious 2 Female 31 lb 3/11/2011 Pharmacist Canada
Primary
Concomitant
Stomatitis Hospitalization 12/14/2009 60 Male 3/25/2011 Other Health Professional Italy
Primary
Secondary
Concomitant
Bone Pain 5/1/2010 Female 4/5/2011 Pharmacist United States
Primary
Concomitant
Chronic Lymphocytic Leukaemia Other Serious 73 Male 159 lb 3/31/2011 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Life Threatening 2/9/2009 54 Male 4/22/2011 Physician Japan
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 4/16/2011 39 Male 135 lb 4/19/2011 Physician United States
Primary
Secondary
Concomitant
Dyspnoea Hospitalization 12/10/2010 80 Female 4/26/2011 Other Health Professional Italy
Primary
Secondary
Concomitant
Dyspnoea Hospitalization 12/10/2010 80 Female 5/6/2011 Other Health Professional Italy
Primary
Secondary
Concomitant
Hepatitis Fulminant Death 3/31/2011 52 Male 5/10/2011 Other Health Professional France
Primary
Secondary
Concomitant
Renal Failure Hospitalization 3/2/2011 70 Male 5/11/2011 Other Health Professional France
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 5/1/2011 32 Male 430 lb 5/5/2011 Physician United States
Primary
Secondary
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 3/2/2011 45 Female 6/3/2011 Consumer United Kingdom
Primary
Secondary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 3/2/2011 45 Female 7/5/2011 Physician Spain
Primary
Secondary
Concomitant
Cholangitis Death 5/3/2011 56 Female 7/11/2011 Other Health Professional Italy
Primary
Secondary
Concomitant
Escherichia Infection Hospitalization 5/1/2011 32 Male 430 lb 8/15/2011 United States
Primary
Secondary
Bacterial Sepsis Death 5/12/2011 62 Male 9/9/2011 Other Health Professional France
Primary
Secondary
Concomitant
General Physical Health Deterioration Hospitalization 8/1/2011 62 Male 9/15/2011 Physician Germany
Primary
Secondary
Concomitant
Septic Shock Disability 9/18/2011 62 Female 148 lb 10/31/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 3/18/2010 13 Male 119 lb 10/31/2011 Consumer United Kingdom
Primary
Secondary
Concomitant
Pneumonia Hospitalization 10/13/2011 70 Female 146 lb 11/2/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Hypoxia Other Serious 5/18/2011 50 Female 84 lb 11/23/2011 Physician Japan
Primary
Concomitant
Thrombocytopenia Life Threatening 11/13/2011 65 Male 218 lb 12/5/2011 Physician United States
Primary
Secondary
Concomitant
Infection Hospitalization 1/29/2009 3 Female 35 lb 2/10/2012 Physician Japan
Primary
Concomitant
Neutropenia Hospitalization 9/11/2011 68 Male 154 lb 2/10/2012 Other Health Professional Denmark
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 5/7/2011 64 Male 179 lb 2/23/2012 Physician Denmark
Primary
Secondary
Concomitant
Uterine Dilation And Curettage Hospitalization 2/23/2012 24 Male 115 lb 2/27/2012 Physician United States
Primary
Secondary
Metabolic Acidosis Death 34 Female 3/27/2012 Physician United Kingdom
Primary
Concomitant
Hyperglycaemia Hospitalization 3/21/2012 20 Female 186 lb 3/23/2012 Physician United States
Primary
Secondary
Concomitant
Hypoaesthesia Other Serious 16 Female 106 lb 4/2/2012 Pharmacist Canada
Primary
Concomitant
Arthralgia Hospitalization 4/15/2009 36 Female 4/10/2012 Japan
Primary
Secondary
Concomitant
Back Pain Hospitalization 2/16/2012 65 Female 163 lb 5/3/2012 Physician Denmark
Primary
Concomitant
Neuropathy Peripheral Other Serious 12 Male 79 lb 5/1/2012 Pharmacist Canada
Primary
Concomitant
Muscle Atrophy Other Serious 4 Male 35 lb 5/1/2012 Pharmacist Canada
Primary
Concomitant
Renal Failure Acute Death 1/1/2009 34 Female 5/9/2012 Physician United Kingdom
Primary
Concomitant
Blood Triglycerides Decreased Hospitalization 4/28/2012 35 Female 224 lb 5/1/2012 United States
Primary
Secondary
Blood Triglycerides Increased Hospitalization 4/28/2012 35 Female 224 lb 5/10/2012 United States
Primary
Secondary
Blood Cholesterol Increased Hospitalization 5/18/2012 35 Female 206 lb 5/23/2012 Physician United States
Primary
Secondary
Disease Progression Hospitalization 1/26/2011 76 Male 163 lb 6/15/2012 Netherlands
Primary
Secondary
Concomitant
Disease Progression Life Threatening 1/26/2011 76 Male 163 lb 6/18/2012 Physician Netherlands
Primary
Concomitant
Weight Decreased Hospitalization 4/10/2012 71 Female 87 lb 6/18/2012 Physician Ukraine
Primary
Secondary
Concomitant
Grip Strength Decreased Hospitalization 6/4/2012 32 Female 161 lb 6/8/2012 United States
Primary
Secondary
Haemolytic Uraemic Syndrome Death 1/29/2009 3 Female 35 lb 7/5/2012 Physician Japan
Primary
Concomitant

Drug Data