Allopurinol combined with Sunitinib Malate

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Hypertension Other Serious Female 6/8/2007 Physician United States
Primary
Concomitant
Renal Failure Hospitalization 10/16/2006 Female 116 lb 8/17/2007 United States
Primary
Secondary
Concomitant
Thrombotic Microangiopathy Other Serious 85 Female 12/22/2007 Physician United States
Primary
Secondary
Concomitant
Thrombotic Microangiopathy Other Serious 85 Female 1/15/2008 Physician United States
Primary
Secondary
Concomitant
Microangiopathic Haemolytic Anaemia Other Serious 57 Female 2/21/2008 Physician United States
Primary
Secondary
Concomitant
Pelvic Fluid Collection Other Serious 5/1/2008 Female 218 lb 11/21/2008 Physician United States
Primary
Concomitant
Urticaria Hospitalization 9/29/2008 12/17/2008 Physician Japan
Primary
Secondary
Concomitant
Tooth Abscess Hospitalization 12/27/2006 12/19/2008 Germany
Primary
Secondary
Concomitant
Urticaria Other Serious 9/19/2008 12/31/2008 Physician Japan
Primary
Secondary
Concomitant
Renal Failure Hospitalization 11/11/2008 66 Male 194 lb 12/22/2008 Physician United States
Primary
Secondary
Concomitant
Pyrexia Other Serious 8/31/2008 1/14/2009 Physician Japan
Primary
Concomitant
Hypomagnesaemia Hospitalization 1/12/2009 Male 194 lb 1/26/2009 Physician United States
Primary
Secondary
Concomitant
Renal Failure Chronic Hospitalization 6/30/2008 2/6/2009 Physician Germany
Primary
Concomitant
Pneumonitis Death 1/1/2008 2/9/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Pyrexia Other Serious 8/31/2008 2/9/2009 Physician Japan
Primary
Concomitant
Chest Discomfort Life Threatening 1/5/2009 2/9/2009 Other Health Professional Singapore
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 6/28/2008 2/11/2009 Physician Japan
Primary
Concomitant
Interacting
Visual Impairment Hospitalization 7/9/2006 2/13/2009 Physician Germany
Primary
Concomitant
Duodenal Ulcer Hospitalization 1/24/2007 2/13/2009 Physician Germany
Primary
Concomitant
Hypomagnesaemia Hospitalization 1/12/2009 Male 194 lb 2/16/2009 Physician United States
Primary
Secondary
Concomitant
Pleural Effusion Hospitalization 11/18/2008 2/19/2009 Physician Japan
Primary
Concomitant
Tooth Abscess Hospitalization 12/27/2006 2/23/2009 Germany
Primary
Secondary
Concomitant
Renal Failure Chronic Hospitalization 6/30/2008 2/27/2009 Physician Germany
Primary
Concomitant
Hypomagnesaemia Hospitalization 1/12/2009 Male 194 lb 3/2/2009 Physician United States
Primary
Secondary
Concomitant
Multi-organ Failure Life Threatening 2/17/2009 3/2/2009 Physician Germany
Primary
Secondary
Concomitant
Pancreatitis Acute Hospitalization 9/2/2007 3/3/2009 Physician Canada
Primary
Secondary
Concomitant
Vasculitis Other Serious 3/11/2009 Physician France
Primary
Concomitant
Myocardial Infarction Other Serious 1/27/2007 3/12/2009 Other Health Professional Germany
Primary
Concomitant
Myocardial Infarction Hospitalization 2/27/2009 3/17/2009 Other Health Professional Brazil
Primary
Concomitant
Psychotic Disorder Due To A General Medical Condition Hospitalization 6/20/2008 3/20/2009 Physician Germany
Primary
Concomitant
Microangiopathic Haemolytic Anaemia Other Serious 57 Female 3/26/2009 Physician United States
Primary
Secondary
Concomitant
Renal Failure Hospitalization 6/2/2008 Male 231 lb 3/30/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Chest Pain Hospitalization 3/14/2009 4/2/2009 Physician Taiwan, Province Of China
Primary
Concomitant
Gastroenteritis Hospitalization 4/14/2008 4/3/2009 Other Health Professional Canada
Primary
Secondary
Concomitant
Multi-organ Failure Life Threatening 2/17/2009 4/6/2009 Germany
Primary
Secondary
Concomitant
Bone Marrow Failure Hospitalization 12/16/2008 4/8/2009 Physician Japan
Primary
Concomitant
Drug Eruption Hospitalization 6/28/2008 Female 126 lb 4/10/2009 Physician Japan
Primary
Concomitant
Interacting
Pneumonitis Death 11/8/2008 4/14/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Chest Pain Hospitalization 3/14/2009 4/15/2009 Physician Taiwan, Province Of China
Primary
Concomitant
Muscular Weakness Hospitalization 3/16/2009 Female 134 lb 4/16/2009 Other Health Professional United States
Primary
Concomitant
Bone Marrow Failure Hospitalization 12/16/2008 4/20/2009 Physician Japan
Primary
Concomitant
Sick Sinus Syndrome Other Serious 4/25/2008 4/23/2009 Physician Japan
Primary
Concomitant
Chest Pain Hospitalization 3/14/2009 4/24/2009 Physician Taiwan, Province Of China
Primary
Secondary
Concomitant
Myocardial Infarction Life Threatening 2/27/2009 4/24/2009 Other Health Professional Brazil
Primary
Concomitant
Pyrexia Other Serious 1/23/2009 4/27/2009 Physician Japan
Primary
Concomitant
Hepatitis Hospitalization 8/2/2006 75 5/12/2009 Physician Germany
Primary
Concomitant
Disease Progression Death 3/16/2009 Female 134 lb 5/13/2009 Other Health Professional United States
Primary
Concomitant
Renal Impairment Other Serious 11/28/2008 66 5/18/2009 Physician Japan
Primary
Concomitant
Hepatic Encephalopathy Hospitalization 4/1/2009 77 5/26/2009 Physician Italy
Primary
Concomitant
Chest Pain Death 5/20/2009 66 5/26/2009 Physician Italy
Primary
Concomitant
Hypotension Hospitalization 8/20/2008 Male 136 lb 5/26/2009 Physician United States
Primary
Concomitant
Acute Myocardial Infarction Death 5/20/2009 66 5/29/2009 Physician Italy
Primary
Concomitant
Hepatic Encephalopathy Hospitalization 4/1/2009 77 6/5/2009 Physician Italy
Primary
Concomitant
Chest Pain Hospitalization 3/14/2009 73 6/9/2009 Physician Taiwan, Province Of China
Primary
Secondary
Concomitant
Pleural Effusion Hospitalization 11/18/2008 73 6/16/2009 Physician Japan
Primary
Concomitant
Acute Myocardial Infarction Death 5/20/2009 66 6/22/2009 Physician Italy
Primary
Concomitant
Proteinuria Hospitalization 4/23/2007 Female 123 lb 6/22/2009 Other Health Professional France
Primary
Concomitant
Pyrexia Other Serious 1/1/2009 70 6/23/2009 Physician Japan
Primary
Concomitant
Respiratory Failure Hospitalization 6/24/2007 Male 163 lb 6/30/2009 Other Health Professional Brazil
Primary
Concomitant
Pyrexia Other Serious 3/16/2009 70 7/6/2009 Physician Japan
Primary
Concomitant
Gastroenteritis Hospitalization 4/14/2008 79 7/7/2009 Other Health Professional Canada
Primary
Secondary
Concomitant
Gastroenteritis Hospitalization 4/14/2008 79 7/15/2009 Other Health Professional Canada
Primary
Secondary
Concomitant
Gastroenteritis Hospitalization 4/14/2008 79 7/29/2009 Other Health Professional Canada
Primary
Secondary
Concomitant
Hyponatraemia Hospitalization 8/7/2009 60 8/18/2009 Other Health Professional Colombia
Primary
Secondary
Concomitant
Arrhythmia Hospitalization 8/2/2009 77 8/25/2009 Physician Germany
Primary
Concomitant
Hyponatraemia Hospitalization 8/7/2009 60 Male 185 lb 8/26/2009 Consumer United States
Primary
Secondary
Concomitant
Hemiparesis Hospitalization 8/18/2009 50 8/31/2009 Physician India
Primary
Concomitant
Respiratory Arrest Other Serious 7/7/2009 78 9/1/2009 Physician Japan
Primary
Secondary
Concomitant
Platelet Count Decreased Other Serious 6/1/2009 74 9/11/2009 Physician Japan
Primary
Concomitant
Hemiparesis Hospitalization 8/18/2009 50 9/14/2009 Physician India
Primary
Concomitant
Sick Sinus Syndrome Hospitalization 7/25/2009 77 9/15/2009 Physician Germany
Primary
Concomitant
Septic Shock Life Threatening 1/13/2007 58 10/6/2009 Physician Malaysia
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 7/27/2009 68 10/12/2009 Physician Japan
Primary
Secondary
Concomitant
Hyponatraemia Hospitalization 2/5/2008 66 Male 193 lb 10/2/2009 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 7/25/2006 57 10/13/2009 Physician Malaysia
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 3/12/2009 60 10/13/2009 Physician Japan
Primary
Concomitant
Platelet Count Decreased Hospitalization 7/13/2009 62 10/13/2009 Physician Japan
Primary
Concomitant
Conjunctivitis Infective Hospitalization 73 10/16/2009 Physician Germany
Primary
Concomitant
Angioedema Hospitalization 6/27/2007 66 10/26/2009 Physician Colombia
Primary
Concomitant
Lung Infection Hospitalization 7/27/2009 68 10/28/2009 Physician Japan
Primary
Secondary
Concomitant
Death Death 10/1/2007 45 10/30/2009 Physician Turkey
Primary
Concomitant
Platelet Count Decreased Other Serious 6/2/2009 74 Female 141 lb 11/2/2009 Physician Japan
Primary
Concomitant
Hypothyroidism Hospitalization 3/8/2007 Male 262 lb 11/9/2009 Other Health Professional United States
Primary
Concomitant
Hypotension Hospitalization 8/16/2008 Male 136 lb 11/18/2009 Physician United States
Primary
Concomitant
Respiratory Arrest Other Serious 7/7/2009 78 Male 104 lb 11/23/2009 Physician Japan
Primary
Secondary
Concomitant
Renal Failure Hospitalization 11/11/2009 Male 12/11/2009 Physician Germany
Primary
Concomitant
Platelet Count Decreased Life Threatening 12/2/2009 58 Male 153 lb 12/14/2009 Physician Japan
Primary
Concomitant
Conjunctivitis Infective Hospitalization 73 Male 170 lb 12/16/2009 Physician Germany
Primary
Concomitant
Pyrexia Hospitalization 11/29/2009 70 Female 150 lb 12/23/2009 Physician Germany
Primary
Secondary
Concomitant
Platelet Count Decreased Death 12/2/2009 58 Male 153 lb 12/29/2009 Physician Japan
Primary
Concomitant
Pyrexia Hospitalization 11/29/2009 70 Female 150 lb 12/30/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Platelet Count Decreased Hospitalization 12/7/2009 75 Male 112 lb 1/18/2010 Physician Japan
Primary
Concomitant
Respiratory Arrest Other Serious 7/7/2009 78 Male 104 lb 1/20/2010 Physician Japan
Primary
Secondary
Concomitant
Renal Failure Hospitalization 11/11/2009 Male 1/18/2010 Physician Germany
Primary
Concomitant
Hyponatraemia Hospitalization 8/7/2009 60 Male 184 lb 1/25/2010 Other Health Professional Colombia
Primary
Secondary
Concomitant
Myocardial Infarction Other Serious 1/27/2007 60 Male 194 lb 2/1/2010 Germany
Primary
Concomitant
Lung Infection Hospitalization 7/27/2009 68 Male 132 lb 2/5/2010 Physician Japan
Primary
Secondary
Concomitant
Loss Of Consciousness Hospitalization 8/7/2009 60 Male 185 lb 2/8/2010 Consumer United States
Primary
Secondary
Concomitant
Platelet Count Decreased Hospitalization 12/7/2009 75 Male 112 lb 2/15/2010 Physician Japan
Primary
Concomitant
Pyrexia Other Serious 8/31/2008 74 Male 119 lb 2/19/2010 Physician Japan
Primary
Concomitant
Malaise Hospitalization 10/14/2006 62 Female 123 lb 3/1/2010 Physician France
Primary
Concomitant
Malaise Hospitalization 7/10/2006 74 Female 148 lb 3/1/2010 Physician France
Primary
Concomitant
Platelet Count Decreased Other Serious 7/13/2009 62 Male 131 lb 3/2/2010 Physician Japan
Primary
Concomitant
Pyrexia Hospitalization 11/29/2009 70 Female 150 lb 3/8/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Myocardial Infarction Hospitalization 1/27/2007 60 Male 194 lb 3/10/2010 Germany
Primary
Concomitant
Hyponatraemia Hospitalization 8/7/2009 60 Male 184 lb 3/15/2010 Other Health Professional Colombia
Primary
Secondary
Concomitant
Waist Circumference Increased Hospitalization 11/11/2009 Male 3/15/2010 Physician Germany
Primary
Secondary
Concomitant
Sudden Death Death 12/30/2008 68 Male 152 lb 3/15/2010 Physician Japan
Primary
Concomitant
Pleural Effusion Hospitalization 10/23/2007 76 Male 154 lb 3/18/2010 Other Health Professional Germany
Primary
Concomitant
Hypovolaemic Shock Death 1/27/2009 75 Male 152 lb 3/23/2010 Other Health Professional Spain
Primary
Secondary
Concomitant
Pelvic Fluid Collection Other Serious 5/1/2008 Female 99 lb 3/24/2010 Physician United States
Primary
Secondary
Concomitant
Orthostatic Hypotension Hospitalization 8/1/2007 Male 318 lb 3/25/2010 Other Health Professional United States
Primary
Concomitant
Renal Impairment Other Serious 2/1/2010 59 Male 170 lb 3/26/2010 Physician Japan
Primary
Concomitant
Hyponatraemia Hospitalization 8/7/2009 60 Male 185 lb 3/29/2010 Consumer United States
Primary
Secondary
Concomitant
Hepatic Function Abnormal Other Serious 9/14/2009 72 Male 146 lb 3/30/2010 Physician Japan
Primary
Concomitant
Psychotic Disorder Due To A General Medical Condition Hospitalization 6/20/2008 68 Male 126 lb 4/1/2010 Physician Germany
Primary
Concomitant
Tumour Lysis Syndrome Life Threatening 4/29/2009 76 Male 4/9/2010 Physician Japan
Primary
Concomitant
Lung Infection Hospitalization 7/27/2009 68 Male 132 lb 4/9/2010 Physician Japan
Primary
Secondary
Concomitant
Conjunctivitis Infective Hospitalization 73 Male 170 lb 4/14/2010 Physician Germany
Primary
Concomitant
Interstitial Lung Disease Life Threatening 11/15/2009 67 Male 132 lb 4/20/2010 Physician Japan
Primary
Secondary
Concomitant
Renal Failure Life Threatening 8/17/2006 54 Male 269 lb 4/23/2010 Physician Belgium
Primary
Concomitant
Renal Impairment Other Serious 7/25/2008 76 Female 128 lb 4/26/2010 Physician Mexico
Primary
Secondary
Concomitant
Orthostatic Hypotension Hospitalization 5/1/2006 74 Female 148 lb 4/26/2010 Physician France
Primary
Concomitant
Renal Failure Hospitalization 11/11/2009 66 Male 4/27/2010 Physician Germany
Primary
Secondary
Concomitant
Interstitial Lung Disease Life Threatening 11/15/2009 67 Male 132 lb 5/5/2010 Physician Japan
Primary
Secondary
Concomitant
Tachycardia Hospitalization 4/13/2010 78 Male 5/6/2010 Physician Germany
Primary
Concomitant
Lung Abscess Hospitalization 1/21/2010 72 Male 174 lb 5/7/2010 Physician Japan
Primary
Concomitant
Platelet Count Decreased Death 12/2/2009 58 Male 153 lb 5/10/2010 Physician Japan
Primary
Concomitant
Tumour Lysis Syndrome Life Threatening 4/29/2009 76 Male 5/18/2010 Physician Japan
Primary
Concomitant
Syncope Hospitalization 4/10/2010 78 Male 5/18/2010 Physician Germany
Primary
Concomitant
Hepatic Function Abnormal Other Serious 9/14/2009 72 Male 146 lb 5/26/2010 Physician Japan
Primary
Concomitant
Hepatic Function Abnormal Other Serious 9/14/2009 72 Male 146 lb 6/8/2010 Japan
Primary
Concomitant
Hepatitis Hospitalization 8/2/2006 75 Female 187 lb 6/9/2010 Physician Germany
Primary
Concomitant
General Physical Health Deterioration Hospitalization 12/12/2008 67 Female 150 lb 6/15/2010 Physician Belgium
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 3/24/2010 85 Female 156 lb 6/21/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 3/24/2010 85 Female 156 lb 6/21/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Platelet Count Decreased Other Serious 7/13/2009 62 Male 131 lb 6/22/2010 Physician Japan
Primary
Concomitant
Sick Sinus Syndrome Hospitalization 8/2/2009 77 Female 6/23/2010 Physician Germany
Primary
Concomitant
Lung Abscess Hospitalization 1/21/2010 72 Male 174 lb 6/30/2010 Physician Japan
Primary
Concomitant
General Physical Health Deterioration Hospitalization 12/12/2008 67 Female 150 lb 7/2/2010 Physician Belgium
Primary
Secondary
Concomitant
Sepsis Hospitalization 3/17/2010 74 Male 139 lb 7/7/2010 Physician Taiwan, Province Of China
Primary
Concomitant
Interstitial Lung Disease Life Threatening 11/15/2009 67 Male 132 lb 7/7/2010 Physician Japan
Primary
Secondary
Concomitant
Circulatory Collapse Hospitalization 6/23/2010 58 Male 12 lb 7/7/2010 Physician Ireland
Primary
Secondary
Concomitant
Atrioventricular Block Hospitalization 12/13/2006 54 Female 174 lb 7/9/2010 Physician Italy
Primary
Concomitant
Supraventricular Tachycardia Hospitalization 7/7/2006 72 Male 176 lb 7/12/2010 Physician Italy
Primary
Concomitant
Circulatory Collapse Hospitalization 6/23/2010 58 Male 123 lb 7/15/2010 Physician Ireland
Primary
Secondary
Concomitant
Platelet Count Decreased Death 12/2/2009 58 Male 153 lb 7/15/2010 Physician Japan
Primary
Concomitant
Supraventricular Tachycardia Hospitalization 7/17/2006 72 Male 176 lb 7/16/2010 Physician Italy
Primary
Concomitant
Intestinal Haemorrhage Hospitalization 6/10/2010 74 Male 183 lb 7/27/2010 Other Health Professional Spain
Primary
Secondary
Concomitant
Presyncope Hospitalization 6/23/2010 58 Male 269 lb 7/28/2010 Physician Ireland
Primary
Secondary
Concomitant

Drug Data