Allopurinol combined with Spironolactone

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Productive Cough Other Serious 1/1/2005 87 Male 1/17/2006 Consumer United States
Primary
Concomitant
Venoocclusive Disease Life Threatening 11/23/2005 63 Female 121 lb 1/12/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Neutropenia Required Intervention 74 Male 1/16/2006 Consumer United States
Primary
Secondary
Concomitant
Platelet Count Decreased Other Serious 11/4/2005 72 Female 97 lb 1/18/2006 Physician Japan
Primary
Secondary
Concomitant
Overdose Death Female 256 lb 1/13/2006 Physician Germany
Primary
Concomitant
Cerebral Haematoma Hospitalization 9/26/2004 73 Female 1/26/2006 Other Health Professional France
Primary
Secondary
Concomitant
Pain In Extremity Hospitalization 6/1/2005 Female 1/31/2006 Consumer United States
Primary
Concomitant
Sudden Death Death 1/10/2006 70 Female 256 lb 1/18/2006 Physician Germany
Primary
Concomitant
Rash Hospitalization 9/12/2005 73 Male 1/31/2006 Pharmacist United States
Primary
Concomitant
Renal Failure Hospitalization 11/1/2005 62 Male 2/3/2006 Sweden
Primary
Concomitant
Ventricular Tachycardia Hospitalization 12/6/2005 57 Male Pharmacist United States
Primary
Concomitant
Pyrexia Other Serious 1/1/2003 38 Female 2/13/2006 Physician Germany
Primary
Secondary
Concomitant
Oedema Peripheral Other Serious 10/24/2005 74 Female 195 lb 1/20/2006 Physician United States
Primary
Concomitant
Shock Other Serious 11/4/2005 72 Female 97 lb 2/23/2006 Physician Japan
Primary
Secondary
Concomitant
Hepatitis Toxic Other Serious 10/18/2005 77 Male 3/2/2006 Physician Spain
Primary
Concomitant
Vomiting Life Threatening 1/26/2006 64 Male 3/3/2006
Primary
Secondary
Concomitant
Sudden Death Death 2/6/2006 77 Female 168 lb 2/28/2006 United Kingdom
Primary
Concomitant
Vomiting Life Threatening 1/26/2006 64 Male 3/7/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Epistaxis Hospitalization 1/30/2006 87 Male 3/1/2006 Pharmacist Ireland
Primary
Concomitant
Vomiting Life Threatening 1/26/2006 64 Male 3/7/2006 United Kingdom
Primary
Secondary
Concomitant
Tricuspid Valve Incompetence Hospitalization 63 Male 3/16/2006
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 2/1/2006 74 Male 187 lb 3/20/2006 Other Health Professional France
Primary
Secondary
Concomitant
Urinary Bladder Haemorrhage Hospitalization 61 Male 3/20/2006 Consumer United States
Primary
Concomitant
Tricuspid Valve Incompetence Hospitalization 63 Male 3/21/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Odynophagia Hospitalization 1/15/2006 71 Male 3/10/2006 Physician Japan
Primary
Secondary
International Normalised Ratio Increased Life Threatening 3/3/2006 56 Female 3/16/2006 Ireland
Primary
Concomitant
Angioneurotic Oedema Hospitalization 1/15/2006 71 Male 3/17/2006 Physician Japan
Primary
Secondary
Obstruction Hospitalization 74 Male 3/16/2006 Pharmacist United States
Primary
Secondary
Concomitant
Urine Colour Abnormal Hospitalization 1/28/2005 45 Male 3/27/2006 Physician Philippines
Primary
Concomitant
Tricuspid Valve Incompetence Hospitalization 63 Male 3/28/2006 Other Health Professional United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 1/15/2006 71 Male 4/3/2006 Physician Japan
Primary
Secondary
Circulatory Collapse Hospitalization 1/18/2006 67 Male 165 lb 4/13/2006 Physician Germany
Primary
Concomitant
Restlessness Death 1/10/2006 70 Female 256 lb 3/30/2006 Physician Germany
Primary
Concomitant
Cystitis Haemorrhagic Hospitalization 4/27/2005 61 Male 4/18/2006 Consumer United States
Primary
Concomitant
Sudden Death Death 2/6/2006 77 Female 168 lb 4/13/2006 Other Health Professional United Kingdom
Primary
Concomitant
Thrombotic Thrombocytopenic Purpura Other Serious 9/8/2005 73 Female 4/20/2006 Physician Japan
Primary
Secondary
Pulmonary Toxicity Required Intervention 4/26/2005 72 Male 175 lb 4/20/2006 Pharmacist United States
Primary
Concomitant
Therapy Non-responder Hospitalization 11/16/2005 29 Male 4/19/2006 Physician Australia
Primary
Concomitant
Uterine Leiomyoma Other Serious 1/10/2006 70 Female 256 lb 4/20/2006 Physician Germany
Primary
Concomitant
Sudden Death Death 2/6/2006 55 Female 168 lb 4/25/2006 Other Health Professional United Kingdom
Primary
Concomitant
Weight Decreased Other Serious 12/13/2005 56 Male 220 lb 4/24/2006 Germany
Primary
Concomitant
Renal Failure Other Serious 8/15/2005 58 Female 236 lb 3/2/2006 United States
Primary
Concomitant
Pneumonia Life Threatening 3/3/2006 56 Female 4/26/2006 Pharmacist Ireland
Primary
Concomitant
Vomiting Life Threatening 9/29/2005 68 Female 196 lb 4/25/2006 United States
Primary
Concomitant
Shoulder Pain Life Threatening 1/1/2006 71 Male 123 lb 5/10/2006 Other Health Professional United States
Primary
Concomitant
Jaundice Cholestatic Hospitalization 3/28/2006 67 Female 173 lb 5/11/2006 Pharmacist United States
Primary
Concomitant
Disease Progression Other Serious 3/22/2006 80 Female 5/1/2006 Physician United States
Primary
Concomitant
Vomiting Hospitalization 1/23/2006 67 Male 163 lb 5/22/2006 Physician Germany
Primary
Concomitant
Eosinophilia Other Serious 3/9/2006 93 Female 5/24/2006 France
Primary
Secondary
Concomitant
Urticaria Generalised Hospitalization 2/20/2005 54 Female 130 lb 5/25/2006 Other Health Professional United Kingdom
Primary
Concomitant
Nervousness 6/1/2005 69 Female 139 lb 6/8/2006 Consumer United States
Primary
Concomitant
Weight Increased Other Serious 2/1/2006 73 Male 190 lb 4/20/2006 United States
Primary
Concomitant
Chest Pain Hospitalization 10/31/2004 89 Female 6/8/2006 Other Health Professional Sweden
Primary
Secondary
Concomitant
Skin Nodule Hospitalization 10/1/2003 Female 119 lb 6/22/2006 Germany
Primary
Concomitant
Hyperlipidaemia Life Threatening 9/26/2002 Male 7/6/2006 Physician Japan
Primary
Secondary
Concomitant
Pulmonary Hypertension Hospitalization 10/1/2004 Female 139 lb 7/7/2006 Physician Germany
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 12/4/1998 Male 7/7/2006 Physician Japan
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 2/1/2006 74 Male 187 lb 7/11/2006 Other Health Professional France
Primary
Secondary
Concomitant
Rash Generalised Hospitalization 9/16/2005 59 Female 105 lb 6/30/2006 Physician Japan
Primary
Concomitant
Vomiting Life Threatening 9/29/2005 68 Female 196 lb 7/6/2006 United States
Primary
Concomitant
Hyperkalaemia Hospitalization 5/23/2006 92 Male 7/7/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Gallbladder Cancer Hospitalization 3/14/2006 Male 7/14/2006 Physician Japan
Primary
Concomitant
Infusion Related Reaction Other Serious 1/1/2006 77 Male 7/18/2006 Consumer United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 12/4/1998 Male 7/19/2006 Physician Japan
Primary
Secondary
Concomitant
Pericarditis Constrictive Hospitalization 10/1/2003 Female 119 lb 7/20/2006 Germany
Primary
Concomitant
Blood Glucose Fluctuation Male 7/21/2006 Consumer United States
Primary
Concomitant
Venous Insufficiency Other Serious 9/15/2001 61 Female 181 lb 7/26/2006 Physician France
Primary
Concomitant
White Blood Cell Count Decreased Life Threatening 12/28/2005 58 Male 7/20/2006 Japan
Primary
Concomitant
Vomiting Hospitalization 74 Male 7/21/2006 Other Health Professional Denmark
Primary
Concomitant
Vomiting Hospitalization 74 Male 7/31/2006 Other Health Professional Denmark
Primary
Secondary
Concomitant
Sudden Death Death 2/6/2006 77 Female 168 lb 8/1/2006 Other Health Professional United Kingdom
Primary
Concomitant
Sepsis Other Serious 5/7/2005 71 Female 209 lb 8/10/2006 Physician United States
Primary
Concomitant
Vomiting Other Serious 1/26/2006 64 Male 8/8/2006 Denmark
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 74 Male 8/17/2006 Consumer France
Primary
Concomitant
Infarction Death 8/2/2006 68 Male 198 lb 8/31/2006 Physician France
Primary
Secondary
Concomitant
Infarction Death 8/2/2006 68 Male 198 lb 9/8/2006 Physician France
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 2/1/2006 74 Male 187 lb 9/22/2006 Other Health Professional France
Primary
Secondary
Concomitant
International Normalised Ratio Abnormal Life Threatening 6/4/2006 89 Male 155 lb 6/5/2006 Pharmacist United States
Primary
Concomitant
Stevens-johnson Syndrome Hospitalization 5/11/2006 79 Female 154 lb 10/3/2006 Other Health Professional United Kingdom
Primary
Concomitant
Weight Increased Other Serious 1/1/2004 Male 230 lb 10/3/2006 Physician United States
Primary
Secondary
Concomitant
International Normalised Ratio Increased Hospitalization 9/27/2006 62 Male 230 lb 9/29/2006 Pharmacist United States
Primary
Concomitant
Stevens-johnson Syndrome Hospitalization 79 Female 154 lb 9/29/2006 United Kingdom
Primary
Concomitant
Weight Increased Other Serious 1/1/2004 Male 230 lb 10/5/2006 Physician United States
Primary
Secondary
Concomitant
Vision Blurred Life Threatening 6/19/2006 86 Female 200 lb 9/15/2006 Consumer United States
Primary
Concomitant
Neutropenia Other Serious 74 Female 175 lb 10/10/2006 Physician
Primary
Secondary
Concomitant
Respiratory Tract Infection Hospitalization 9/22/2005 65 183 lb 10/11/2006 Physician Ireland
Primary
Concomitant
Somnolence Hospitalization 8/2/2006 85 Male 10/12/2006 Other Health Professional France
Primary
Secondary
Concomitant
Drug Interaction Potentiation Death 8/2/2006 68 Male 198 lb 10/6/2006 Other Health Professional France
Primary
Secondary
Concomitant
Neutropenia Other Serious 74 Female 10/16/2006 Physician
Primary
Secondary
Concomitant
Staphylococcal Infection Hospitalization 9/16/2005 65 183 lb 10/19/2006 Physician Ireland
Primary
Concomitant
Myalgia Required Intervention 7/27/2006 47 Male 265 lb 9/20/2006 Pharmacist United States
Primary
Concomitant
Neutropenia Other Serious 74 Female 10/23/2006 Physician
Primary
Secondary
Concomitant
Neutropenia Other Serious 74 Female 175 lb 10/18/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Nodal Rhythm Hospitalization 9/25/2006 80 Female 10/16/2006 Physician Poland
Primary
Secondary
Concomitant
Myocardial Infarction Hospitalization 9/14/2006 Male 10/23/2006 Pharmacist United States
Primary
Concomitant
Renal Failure Hospitalization 10/16/2006 66 Female 116 lb 10/27/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Dysgeusia 84 Female 11/13/2006 Consumer United States
Primary
Secondary
Concomitant
Skin Discolouration 57 Male 11/13/2006 Consumer United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 7/16/2006 Female 227 lb 11/14/2006 Physician Germany
Primary
Concomitant
Vomiting Hospitalization 7/16/2006 Female 227 lb 11/14/2006 Physician Germany
Primary
Concomitant
Renal Failure Acute Hospitalization 10/16/2006 66 Female 116 lb 11/15/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Urethral Haemorrhage Other Serious 10/30/2006 Male 181 lb 12/4/2006 Physician Czech Republic
Primary
Concomitant
International Normalised Ratio Increased Hospitalization 11/27/2006 59 Male 223 lb 11/30/2006 Pharmacist United States
Primary
Concomitant
Rash Other Serious 8/1/2006 Female 121 lb 12/21/2006 Physician Hungary
Primary
Concomitant
Right Ventricular Failure Death 10/27/2004 58 Female 12/15/2006 Physician United States
Primary
Concomitant
Urine Output Decreased Hospitalization 11/18/2006 62 Male 187 lb 1/3/2007 Physician Spain
Primary
Secondary
Vertigo 9/3/2006 66 Female 176 lb 10/16/2006 Consumer United States
Primary
Concomitant
Sepsis Disability 11/1/2006 85 Female 2/16/2007 Physician Japan
Primary
Concomitant
Proteinuria Disability 1/9/2007 52 Female 262 lb 3/5/2007 Other Health Professional United Kingdom
Primary
Concomitant
Septic Shock Hospitalization 11/18/2006 62 NotSpecified 187 lb 3/6/2007 Physician Spain
Primary
Secondary
Syncope Hospitalization 3/8/2007 67 Male 3/22/2007 Other Health Professional Germany
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Hospitalization 93 Female 3/27/2007 Italy
Primary
Secondary
Concomitant
Respiratory Failure Life Threatening 4/10/2007 56 Female 4/17/2007 Other Health Professional United States
Primary
Concomitant
Spinal Fracture Hospitalization 7/23/2006 82 Female 4/25/2007 Other Health Professional France
Primary
Secondary
Anti-neutrophil Cytoplasmic Antibody Positive Vasculitis Other Serious 72 Female 121 lb 4/19/2007 Physician Japan
Primary
Concomitant
Ventricular Hypertrophy Other Serious 1/5/2007 65 Male 4/20/2007 Japan
Primary
Concomitant
Malaise Hospitalization 7/23/2006 82 Female 4/30/2007 Other Health Professional France
Primary
Secondary
Respiratory Failure Hospitalization 4/10/2007 56 Female 4/30/2007 Other Health Professional United States
Primary
Concomitant
Cardiac Failure Congestive Hospitalization 10/29/2006 66 Male 217 lb 1/30/2007 United States
Primary
Concomitant
Renal Impairment Hospitalization 3/12/2007 77 Female 4/26/2007 United Kingdom
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 3/12/2007 77 Female 4/28/2007 United Kingdom
Primary
Secondary
Concomitant
Productive Cough 12/11/2006 61 Male 2/16/2007 United States
Primary
Concomitant
Renal Failure Acute Life Threatening 8/27/2006 72 Male 5/8/2007 Spain
Primary
Secondary
Concomitant
Pallor Hospitalization 5/11/2006 79 Female 154 lb 5/18/2007 Other Health Professional United Kingdom
Primary
Concomitant
Renal Failure Chronic Hospitalization 6/29/2002 78 Female 5/22/2007 Other Health Professional United States
Primary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 1/28/2007 60 Female 5/25/2007 Other Health Professional Sweden
Primary
Secondary
Concomitant
Hyperlipidaemia Life Threatening 9/26/2002 Male 5/25/2007 Physician Japan
Primary
Secondary
Concomitant
Supraventricular Extrasystoles Other Serious 1/5/2007 65 Male 5/21/2007 Japan
Primary
Concomitant
Nasal Septum Perforation Other Serious 8/19/2002 74 Male 131 lb 5/16/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Failure Hospitalization 10/16/2006 Female 116 lb 6/1/2007 United States
Primary
Secondary
Concomitant
Respiratory Disorder Hospitalization Male 220 lb 6/5/2007 Consumer France
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 7/1/2004 Male 193 lb 6/5/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Hyperlipidaemia Life Threatening 9/26/2002 Male 6/9/2007 Physician Japan
Primary
Secondary
Concomitant
Oedema Peripheral Other Serious 12/1/2006 64 Female 148 lb 6/12/2007 United States
Primary
Secondary
Concomitant
Pneumonia Hospitalization 1/8/2007 81 Male 6/18/2007 Other Health Professional France
Primary
Concomitant
Hepatic Enzyme Increased Other Serious 5/29/2007 37 Male 292 lb 6/18/2007 Pharmacist United States
Primary
Concomitant
Vitamin D Deficiency Other Serious 1/1/2004 Male 159 lb 6/22/2007 Other Health Professional United States
Primary
Concomitant
Deafness Neurosensory Other Serious 6/5/2007 66 Male 6/22/2007 Physician Germany
Primary
Concomitant
Myocardial Infarction Hospitalization 6/5/2007 66 Male 6/29/2007 Consumer United States
Primary
Concomitant
Neck Pain Disability 86 220 lb 7/9/2007 Other Health Professional United Kingdom
Primary
Concomitant
Hyperlipidaemia Life Threatening 9/26/2002 Male 7/11/2007 Physician Japan
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 6/11/2007 79 Female 201 lb 7/14/2007 Physician Germany
Primary
Secondary
Concomitant
Neck Pain Disability 86 220 lb 7/18/2007 United Kingdom
Primary
Concomitant
Peritonitis Life Threatening 10/7/2006 72 Female 78 lb 7/20/2007 Physician Japan
Primary
Secondary
Concomitant
Inner Ear Disorder Other Serious 6/5/2007 66 Male 7/26/2007 Physician Germany
Primary
Concomitant
Right Ventricular Failure Hospitalization 4/16/2007 47 Female 168 lb 7/10/2007 Physician United States
Primary
Concomitant
No Therapeutic Response Life Threatening 7/12/2007 Female 8/3/2007 Physician Japan
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 1/1/2007 Male 240 lb 8/10/2007 Physician United States
Primary
Concomitant
Insomnia 1/1/2007 58 Male 190 lb 7/10/2007 Consumer United States
Primary
Concomitant
Syncope Hospitalization 3/8/2007 67 Male 8/14/2007 Other Health Professional Germany
Primary
Secondary
Concomitant

Drug Data