Allopurinol combined with Spiriva

Reports:


Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Cardiac Arrest Death 12/19/2005 83 Male 1/5/2006 Physician
Primary
Concomitant
Rhabdomyolysis Other Serious 12/10/2005 69 Female 163 lb 2/1/2006 Pharmacist Japan
Primary
Concomitant
Ventricular Hypertrophy Other Serious 12/19/2005 83 Male 2/1/2006 Physician
Primary
Concomitant
White Blood Cell Count Increased Other Serious 1/1/2005 67 Male 2/2/2006 Consumer United States
Primary
Concomitant
Oedema Peripheral Hospitalization 55 Male 388 lb 2/7/2006 Pharmacist United States
Primary
Concomitant
Rhabdomyolysis Other Serious 12/10/2005 69 Female 163 lb 2/24/2006 Pharmacist Japan
Primary
Concomitant
Oedema Peripheral Hospitalization 55 Male 388 lb 2/22/2006 Pharmacist United States
Primary
Concomitant
Aortic Dissection Death Male 3/29/2006
Primary
Secondary
Syncope Hospitalization 2/10/2006 75 Male 192 lb 4/4/2006 Physician Germany
Primary
Concomitant
Oedema Peripheral Hospitalization 55 Male 388 lb 1/25/2006 Pharmacist United States
Primary
Concomitant
Pneumonia Hospitalization 2/27/2006 76 Male 150 lb 4/28/2006 Physician Japan
Primary
Concomitant
Dyspnoea 8/30/2005 69 Male 2/21/2006 United States
Primary
Concomitant
Jaundice Cholestatic Hospitalization 3/28/2006 67 Female 173 lb 5/11/2006 Pharmacist United States
Primary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 3/2/2006 71 Female 5/24/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Respiratory Distress Hospitalization 6/30/2006 71 Male 7/14/2006 Physician United States
Primary
Concomitant
Disease Progression Death 6/19/2006 52 Male 143 lb 7/20/2006 Physician Belgium
Primary
Concomitant
Epistaxis 10/1/2005 83 Female 8/4/2006 Physician United States
Primary
Concomitant
Nausea Disability 2/14/2006 59 Male 7/12/2006 Physician United States
Primary
Concomitant
Wheezing Other Serious 7/1/2006 78 Male 175 lb 8/11/2006 United States
Primary
Concomitant
Somnolence Hospitalization 7/21/2006 Male 150 lb 8/21/2006 Physician United Kingdom
Primary
Concomitant
Neoplasm Progression Life Threatening 6/2/2006 Male 8/23/2006
Primary
Concomitant
Neoplasm Progression Life Threatening 6/2/2006 Male 8/30/2006
Primary
Secondary
Concomitant
Mitochondrial Myopathy Other Serious 52 Female 8/31/2006 Austria
Primary
Concomitant
Neoplasm Progression Life Threatening 6/2/2006 Male 9/18/2006
Primary
Concomitant
Tumour Invasion Life Threatening 6/2/2006 Male 9/25/2006
Primary
Concomitant
Sudden Death Death 4/5/2005 Male 9/28/2006 Physician United Kingdom
Primary
Secondary
Psoriasis Other Serious 7/1/2006 67 Male 10/9/2006 Consumer United States
Primary
Concomitant
Renal Failure Hospitalization 78 Male 99 lb 10/10/2006 Consumer United States
Primary
Concomitant
Respiratory Tract Infection Hospitalization 9/22/2005 65 183 lb 10/11/2006 Physician Ireland
Primary
Concomitant
Staphylococcal Infection Hospitalization 9/16/2005 65 183 lb 10/19/2006 Physician Ireland
Primary
Concomitant
Drug Ineffective 1/1/2005 Male 8/22/2006 United States
Primary
Concomitant
Bone Pain 3/1/2006 72 Female 271 lb 8/22/2006 United States
Primary
Concomitant
Rash 1/1/2006 Male 10/30/2006 Consumer United States
Primary
Concomitant
Gynaecomastia Hospitalization 1/1/2005 Male 10/31/2006 Pharmacist
Primary
Secondary
Rash Life Threatening 6/15/2006 Male 397 lb 11/9/2006 Physician France
Primary
Secondary
Concomitant
Spinal Fracture Other Serious 5/1/2006 60 Female 11/15/2006 Physician United States
Primary
Concomitant
Neoplasm Malignant Other Serious 5/1/2006 60 Female 7/7/2006 Physician United States
Primary
Concomitant
Tachycardia Hospitalization 9/16/2006 73 Male 12/6/2006 Switzerland
Primary
Secondary
Concomitant
Somnolence Other Serious 12/1/2005 54 Female 123 lb 9/7/2006 United States
Primary
Concomitant
Somnolence Other Serious 12/1/2005 54 Female 123 lb 9/7/2006 United States
Primary
Concomitant
Drug Ineffective 12/1/2005 75 Female 11/21/2006 United States
Primary
Concomitant
Vomiting 9/1/2006 85 Male 11/21/2006 United States
Primary
Concomitant
Intestinal Dilatation Other Serious 2/26/2007 78 Male 165 lb 3/6/2007 Physician Japan
Primary
Concomitant
Lung Disorder Hospitalization 1/30/2007 64 Female 157 lb 3/6/2007 Physician Germany
Primary
Secondary
Concomitant
Pneumonia Hospitalization 11/1/2005 Female 3/14/2007 Consumer United States
Primary
Concomitant
Periodontal Disease Hospitalization 1/30/2007 Male 159 lb 3/15/2007 Physician United Kingdom
Primary
Concomitant
Intestinal Dilatation Other Serious 2/26/2007 78 Male 165 lb 3/19/2007 Physician Japan
Primary
Concomitant
Intestinal Dilatation Other Serious 2/26/2007 78 Male 165 lb 3/23/2007 Physician Japan
Primary
Concomitant
Upper Limb Fracture Other Serious 1/1/2005 81 Female 141 lb 3/23/2007 Physician Germany
Primary
Concomitant
Epistaxis Hospitalization 3/27/2006 71 Male 165 lb 3/26/2007 Physician Germany
Primary
Secondary
Concomitant
Ileus Paralytic Hospitalization 1/1/2006 Male 95 lb 3/29/2007 Physician Germany
Primary
Concomitant
Sputum Retention Other Serious 3/18/2007 Female 200 lb 3/30/2007 Consumer United States
Primary
Concomitant
Ileus Hospitalization 3/3/2007 Male 154 lb 4/3/2007 Physician Japan
Primary
Concomitant
Cardiac Failure Congestive Hospitalization 10/29/2006 66 Male 217 lb 1/30/2007 United States
Primary
Concomitant
Pyrexia Other Serious 2/26/2007 78 Male 165 lb 5/14/2007 Physician Japan
Primary
Concomitant
Tachycardia Hospitalization 4/10/2007 68 Male 5/2/2007 Physician Germany
Primary
Concomitant
Optic Ischaemic Neuropathy Other Serious 4/1/2003 Male 250 lb 5/16/2007 Lawyer United States
Primary
Concomitant
Tachypnoea Hospitalization 3/18/2007 66 Male 5/18/2007 Consumer France
Primary
Concomitant
Sepsis Death 2/16/2007 81 Male 187 lb 5/22/2007
Primary
Secondary
Concomitant
Visual Acuity Reduced 3/1/2006 80 Male 138 lb 2/22/2007 United States
Primary
Concomitant
Rheumatoid Arthritis Other Serious 2/1/2006 81 Male 5/31/2007 Physician Greece
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 2/16/2007 81 Male 6/1/2007 Other Health Professional France
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 2/16/2007 81 Male 6/1/2007 Other Health Professional France
Primary
Secondary
Concomitant
Pleural Effusion Hospitalization 5/30/2007 Female 161 lb 6/21/2007 United States
Primary
Concomitant
White Blood Cell Count Increased Life Threatening 5/8/2007 59 Female 146 lb 7/10/2007 Physician Belgium
Primary
Secondary
Concomitant
Pneumonia Other Serious 3/18/2007 Female 200 lb 7/18/2007 Consumer United States
Primary
Concomitant
Interstitial Lung Disease Hospitalization 7/17/2007 70 Male 7/23/2007 Pharmacist Japan
Primary
Secondary
Interstitial Lung Disease Hospitalization 7/17/2007 70 Male 7/25/2007 Pharmacist Japan
Primary
Secondary
No Reaction On Previous Exposure To Drug Other Serious 4/10/2007 68 Male 7/13/2007 Physician Germany
Primary
Concomitant
General Physical Health Deterioration Hospitalization 7/21/2006 53 Male 150 lb 8/23/2007 Physician United Kingdom
Primary
Concomitant
Periodontal Disease Hospitalization 1/30/2007 67 Male 159 lb 8/24/2007 Physician United Kingdom
Primary
Concomitant
Visual Disturbance Other Serious 1/1/2006 Male 155 lb 8/24/2007 Consumer United States
Primary
Concomitant
Urine Flow Decreased 5/1/2007 70 Male 8/30/2007 Consumer United States
Primary
Concomitant
International Normalised Ratio Increased Other Serious 7/31/2007 67 Male 225 lb 8/28/2007 United Kingdom
Primary
Concomitant
Drug Ineffective 1/1/2007 Male 9/4/2007 Consumer United States
Primary
Concomitant
Weight Increased Life Threatening 6/1/2007 70 Male 8/31/2007 Germany
Primary
Concomitant
International Normalised Ratio Increased Other Serious 7/31/2007 67 Male 225 lb 8/31/2007 United Kingdom
Primary
Concomitant
Death Death 8/22/2007 Female 9/10/2007 Other Health Professional United States
Primary
Concomitant
International Normalised Ratio Increased Other Serious 8/6/2007 67 Male 225 lb 9/7/2007 United Kingdom
Primary
Concomitant
Overdose 6/13/2007 78 Male 7/26/2007 United States
Primary
Secondary
Concomitant
Pneumonia Hospitalization 8/1/2007 86 Male 10/24/2007 Consumer United States
Primary
Concomitant
Tendon Disorder Other Serious 5/1/2005 66 Male 216 lb 10/29/2007 United States
Primary
Concomitant
Prostatic Specific Antigen Increased Other Serious 10/17/2007 67 Male 204 lb 11/15/2007 Consumer United States
Primary
Secondary
Concomitant
Chronic Obstructive Pulmonary Disease Death 8/22/2007 Female 11/16/2007 Other Health Professional United States
Primary
Concomitant
Pleural Effusion Hospitalization 5/30/2007 Female 161 lb 11/21/2007 United States
Primary
Concomitant
Staphylococcal Bacteraemia Other Serious 1/1/2007 Male 283 lb 11/28/2007 Consumer United States
Primary
Secondary
Concomitant
Overdose 6/13/2007 78 Male 10/22/2007 United States
Primary
Secondary
Concomitant
Drug Ineffective 10/28/2007 Female 12/4/2007 Consumer United States
Primary
Concomitant
Drug Ineffective Male 12/21/2007 Consumer United States
Primary
Concomitant
Stomach Discomfort 5/17/2006 62 Male 10/8/2007 Consumer United States
Primary
Concomitant
Dyspnoea 11/12/2007 Male 1/7/2008 Consumer United States
Primary
Concomitant
Drug Ineffective 8/1/2007 69 Male 1/9/2008 Consumer United States
Primary
Concomitant
Sudden Death Death 4/5/2007 57 Female 1/10/2008 Physician Belgium
Primary
Concomitant
Sudden Death Death 4/5/2007 57 Female 1/10/2008 Physician Belgium
Primary
Concomitant
Pyrexia Other Serious 12/1/2007 Male 1/14/2008 Physician France
Primary
Secondary
Concomitant
Diarrhoea Haemorrhagic Hospitalization 10/10/2007 Male 232 lb 1/16/2008 Physician United States
Primary
Concomitant
Pharmaceutical Product Complaint 11/16/2007 70 Male 238 lb 1/29/2008 Physician United States
Primary
Concomitant
Urinary Retention Hospitalization 6/13/2007 60 Male 215 lb 1/18/2008 Physician United States
Primary
Concomitant
Spinal Column Stenosis 11/12/2007 Male 2/8/2008 Consumer United States
Primary
Concomitant
Pyrexia Other Serious 12/1/2007 Male 227 lb 2/15/2008 Physician France
Primary
Secondary
Concomitant
Thrombocytopenia 9/28/2007 75 Male 10/10/2007 Other Health Professional United States
Primary
Concomitant
Diplopia 12/30/2007 Male 2/21/2008 Consumer United States
Primary
Concomitant
Nervousness Female 3/5/2008 Consumer United States
Primary
Concomitant
Spinal Column Stenosis 11/12/2007 Male 3/6/2008 Consumer United States
Primary
Concomitant
Somnolence Disability 2/25/2008 76 Male 172 lb 3/12/2008 Consumer Brazil
Primary
Secondary
Concomitant
Cardiac Arrest Death 2/26/2007 Female 198 lb 4/4/2008 Other Health Professional United States
Primary
Concomitant
Cardiac Arrest Death 2/26/2007 Female 198 lb 4/11/2008 Other Health Professional United States
Primary
Concomitant
Pruritus Other Serious 1/25/2008 Male 419 lb 4/10/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Pruritus Other Serious 1/25/2008 Male 190 lb 4/10/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Convulsion Other Serious 1/5/2007 Male 209 lb 4/15/2008 Consumer United States
Primary
Concomitant
Skin Exfoliation Other Serious 6/29/2005 83 Male 197 lb 4/30/2008 Other Health Professional Germany
Primary
Concomitant
Middle Insomnia 1/1/2006 Female 5/6/2008 Consumer United States
Primary
Concomitant
Weight Increased Other Serious 2/14/2008 67 Male 216 lb 5/13/2008 Physician United States
Primary
Concomitant
Rectal Haemorrhage Hospitalization 4/10/2008 88 Female 5/15/2008 Physician Italy
Primary
Secondary
Concomitant
Urinary Retention Life Threatening Male 5/20/2008 Other Health Professional France
Primary
Secondary
Concomitant
Atrioventricular Block Complete Hospitalization 4/10/2008 86 Male 154 lb 5/22/2008 Physician
Primary
Concomitant
Pneumonia Life Threatening 1/1/2005 78 Male 241 lb 5/27/2008 Physician Canada
Primary
Concomitant
Middle Insomnia 1/1/2006 Female 5/30/2008 Consumer United States
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 1/1/2007 Male 6/11/2008 Consumer United States
Primary
Concomitant
Pyrexia Hospitalization 5/25/2008 72 Male 6/18/2008 Other Health Professional Germany
Primary
Secondary
Concomitant
Skin Necrosis Other Serious 6/29/2005 83 Male 197 lb 7/3/2008 Other Health Professional Germany
Primary
Concomitant
Pulmonary Oedema Other Serious 6/16/2008 7/11/2008 Physician Canada
Primary
Concomitant
Ventricular Tachycardia Other Serious 1/1/2008 Male 7/14/2008 Pharmacist Australia
Primary
Concomitant
Ventricular Tachycardia Other Serious 1/1/2008 Male 7/21/2008 Pharmacist Australia
Primary
Concomitant
Pulmonary Oedema Other Serious 6/16/2008 7/24/2008 Physician Canada
Primary
Concomitant
Thrombotic Thrombocytopenic Purpura Hospitalization 7/4/2008 61 Female 7/11/2008 Physician United States
Primary
Concomitant
Pulmonary Oedema Other Serious 6/16/2008 7/28/2008 Physician Canada
Primary
Concomitant
Cardiac Disorder Hospitalization Male 8/7/2008 Consumer United States
Primary
Concomitant
Thrombotic Thrombocytopenic Purpura Hospitalization 7/4/2008 Female 8/13/2008 Physician United States
Primary
Concomitant
Gingivitis Hospitalization 1/30/2007 67 Male 159 lb 8/18/2008 Physician Germany
Primary
Concomitant
Cardiac Disorder Hospitalization Male 8/19/2008 Physician United States
Primary
Concomitant
Weight Decreased 1/1/2005 78 Male 225 lb 7/7/2008 Consumer United States
Primary
Concomitant
Thrombocytopenia Required Intervention 7/3/2007 80 Male 289 lb 8/22/2008 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 1/1/2007 Male 8/28/2008 Consumer United States
Primary
Concomitant
Tooth Infection Other Serious 5/1/2005 Male 216 lb 9/3/2008 United States
Primary
Concomitant
Thrombotic Thrombocytopenic Purpura Other Serious 7/4/2008 Female 9/9/2008 Physician United States
Primary
Concomitant
Lung Neoplasm Malignant Other Serious 6/1/2008 55 Female 9/25/2008 United States
Primary
Secondary
Concomitant
Rash Hospitalization 8/1/2008 70 Female 10/15/2008 Consumer France
Primary
Concomitant
Tumour Lysis Syndrome Hospitalization 6/13/2007 Male 215 lb 10/28/2008 United States
Primary
Concomitant
Malaise Hospitalization 8/30/2008 71 Male 101 lb 10/31/2008 Other Health Professional Japan
Primary
Concomitant
Convulsion Hospitalization 10/15/2008 Female 11/13/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Vision Blurred 11/1/2008 Male 11/20/2008 Consumer
Primary
Concomitant
Splenic Granuloma Hospitalization 10/20/2008 70 Male 203 lb 11/18/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Pain 2/1/2008 77 Male 11/14/2008 United States
Primary
Concomitant
Pulmonary Congestion Other Serious Female 140 lb 12/2/2008 Consumer United States
Primary
Concomitant
Dry Mouth 1/1/2007 Male 12/5/2008 Consumer
Primary
Concomitant
Vision Blurred 10/1/2008 Male 12/5/2008 Consumer
Primary
Concomitant
Vision Blurred 11/24/2008 Male 12/9/2008 Consumer
Primary
Concomitant
Femur Fracture Hospitalization 1/1/2007 Male 12/9/2008 Consumer
Primary
Concomitant
Convulsion Hospitalization 10/15/2008 Female 12/10/2008 Physician United Kingdom
Primary
Secondary
Concomitant