Allopurinol combined with Sodium Bicarbonate

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
White Blood Cell Count Decreased Hospitalization 11/9/2005 64 Male 171 lb 1/5/2006 United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 11/1/2005 Female 1/27/2006 Physician
Primary
Secondary
Concomitant
Gamma-glutamyltransferase Increased Other Serious 12/12/2005 Female 127 lb 1/31/2006 Physician Spain
Primary
Concomitant
Hepatic Failure Death 81 Female 2/3/2006 Other Health Professional Australia
Primary
Secondary
Concomitant
Thrombophlebitis Hospitalization 5/14/2005 33 Male 2/7/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Thrombophlebitis Hospitalization 5/14/2005 33 Male 2/10/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Gamma-glutamyltransferase Increased Other Serious 12/12/2005 Female 127 lb 2/15/2006 Physician Spain
Primary
Concomitant
Sudden Cardiac Death Death 11/30/2005 66 Male 174 lb 2/17/2006 Physician Germany
Primary
Concomitant
Vomiting Hospitalization 11/1/2005 Female 3/17/2006 Physician
Primary
Secondary
Concomitant
Splenomegaly Hospitalization 9/30/2003 50 Female 129 lb 3/15/2006 United States
Primary
Concomitant
Renal Failure Hospitalization 2/21/2006 75 Female 150 lb 3/14/2006 Physician Italy
Primary
Concomitant
White Blood Cell Count Decreased Life Threatening 1/1/2006 52 Male 3/23/2006 Japan
Primary
Concomitant
Vomiting Hospitalization 11/1/2005 Female 4/6/2006 Physician
Primary
Secondary
Concomitant
Respiratory Failure Life Threatening 3/3/2006 11 Female 3/23/2006 Physician Portugal
Primary
Concomitant
Gamma-glutamyltransferase Increased Other Serious 12/12/2005 Female 127 lb 4/18/2006 Physician Spain
Primary
Concomitant
Stomatitis Hospitalization 3/27/2006 Male 5/8/2006 Physician Germany
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Life Threatening 10/20/2005 76 Female 170 lb 5/8/2006 Physician Austria
Primary
Secondary
Concomitant
Renal Failure Disability 12/27/2005 Male 6/1/2006 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Life Threatening 1/23/2006 52 Male 6/2/2006 Other Health Professional Japan
Primary
Concomitant
White Blood Cell Count Decreased Life Threatening 1/15/2006 59 Male 6/7/2006 Japan
Primary
Concomitant
Renal Failure Hospitalization 12/27/2005 Male 6/15/2006 Physician Japan
Primary
Secondary
Concomitant
Hyperphosphataemia Other Serious 17 Male 162 lb 6/14/2006 Physician United States
Primary
Secondary
Concomitant
Renal Failure Hospitalization 12/27/2005 Male 119 lb 6/23/2006 Physician Japan
Primary
Secondary
Concomitant
Anaemia Hospitalization 5/25/2006 Male 164 lb 7/28/2006 Physician United States
Primary
Concomitant
Restlessness Other Serious 3/5/2006 76 Male 7/11/2006 Other Health Professional United States
Primary
Concomitant
Blood Erythropoietin Increased Hospitalization 5/25/2006 Male 164 lb 9/6/2006 Physician United States
Primary
Concomitant
Ventricular Tachycardia Other Serious 6/6/2005 69 Male 174 lb 8/29/2006 Other Health Professional United States
Primary
Concomitant
White Blood Cell Count Decreased Life Threatening 1/15/2006 59 Male 9/19/2006 Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 1/30/2006 59 Male 9/26/2006 Japan
Primary
Secondary
Concomitant
Weight Decreased Other Serious 8/24/2006 69 Male 165 lb 10/3/2006 Physician France
Primary
Concomitant
Therapeutic Response Decreased Male 12/22/2006 Pharmacist United States
Primary
Concomitant
Pyrexia 1/1/2005 Male 12/22/2006 Other Health Professional United States
Primary
Concomitant
Haematuria Other Serious 11/27/2006 56 Female 1/2/2007 Physician Japan
Primary
Concomitant
Haematuria Other Serious 11/26/2006 Female 91 lb 1/17/2007 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 12/4/2006 71 Male 1/17/2007 Physician Japan
Primary
Secondary
Concomitant
Tachycardia Death 1/12/2007 72 Male 1/25/2007 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 12/4/2006 71 Male 1/25/2007 Physician Japan
Primary
Secondary
Concomitant
Haematuria Other Serious 11/26/2006 Female 91 lb 2/2/2007 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 12/4/2006 71 Male 2/5/2007 Physician Japan
Primary
Secondary
Concomitant
Urinary Retention Hospitalization 1/12/2007 71 Female 2/19/2007 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 12/4/2006 71 Male 2/12/2007 Physician Japan
Primary
Secondary
Concomitant
Pneumonia Hospitalization 2/18/2007 Male 97 lb 3/7/2007 Korea, Republic Of
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 12/4/2006 71 Male 2/28/2007 Physician Japan
Primary
Secondary
Concomitant
Urinary Retention Hospitalization 1/12/2007 71 Female 3/5/2007 Physician Japan
Primary
Concomitant
Pneumonia Hospitalization 2/18/2007 Male 97 lb 3/19/2007 Korea, Republic Of
Primary
Concomitant
Tachycardia Death 1/12/2007 72 Male 3/14/2007 Physician Japan
Primary
Concomitant
Urinary Retention Hospitalization 1/12/2007 71 Female 3/16/2007 Physician Japan
Primary
Concomitant
Pneumonia Hospitalization 2/18/2007 Male 97 lb 4/2/2007 Korea, Republic Of
Primary
Concomitant
Ventricular Dysfunction Other Serious 2/26/2007 Male 173 lb 4/11/2007 Physician United States
Primary
Concomitant
Myelodysplastic Syndrome Disability 1/1/2007 Male 137 lb 4/17/2007 Physician Belgium
Primary
Concomitant
Renal Failure Death 2/17/2004 Male 134 lb 4/19/2007 Physician Italy
Primary
Concomitant
Viral Infection Hospitalization 11/2/2006 58 Male 268 lb 5/10/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Failure Chronic Hospitalization 4/13/2007 72 Male 152 lb 5/18/2007 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 12/4/2006 71 Male 5/18/2007 Physician Japan
Primary
Concomitant
Pulmonary Mass Other Serious 12/4/2006 71 Male 5/24/2007 Physician Japan
Primary
Concomitant
Renal Failure Chronic Hospitalization 4/13/2007 72 Male 152 lb 6/1/2007 Physician Japan
Primary
Concomitant
Somnolence 1/1/2007 82 Male 160 lb 4/12/2007 Consumer United States
Primary
Concomitant
Vomiting Other Serious 1/1/2006 Female 106 lb 6/5/2007 Physician Japan
Primary
Secondary
Concomitant
Aplasia Pure Red Cell Disability 1/1/2007 Male 137 lb 6/18/2007 Physician Belgium
Primary
Secondary
Concomitant
Sepsis Hospitalization 4/2/2007 63 Male 6/11/2007 Physician Japan
Primary
Concomitant
Troponin I Increased Other Serious 2/25/2007 61 Female 148 lb 6/8/2007 Pharmacist United Kingdom
Primary
Concomitant
Subdural Haemorrhage Other Serious 9/1/2006 Male 6/21/2007 Physician United States
Primary
Concomitant
Rash Other Serious 4/2/2007 71 Male 6/15/2007 Physician Japan
Primary
Concomitant
Nephrogenic Fibrosing Dermopathy Death 15 Male 77 lb 6/27/2007 Consumer United States
Primary
Secondary
Concomitant
Vomiting Other Serious 1/1/2006 Female 106 lb 6/27/2007 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 12/4/2006 71 Male 6/28/2007 Physician Japan
Primary
Concomitant
Venoocclusive Liver Disease Hospitalization 10/22/2006 11 Female 75 lb 7/2/2007 Physician United States
Primary
Secondary
Concomitant
Pleural Effusion Hospitalization 9/20/2005 59 Male 143 lb 7/13/2007 Physician Japan
Primary
Concomitant
Skin Lesion Other Serious 4/1/2007 Male 7/16/2007 Physician Australia
Primary
Concomitant
Vomiting Other Serious 1/1/2006 Female 106 lb 7/19/2007 Physician Japan
Primary
Secondary
Concomitant
Skin Lesion Other Serious 4/1/2007 Male 7/23/2007 Physician Australia
Primary
Concomitant
Renal Failure Other Serious 8/24/2006 69 Male 165 lb 7/26/2007 Physician France
Primary
Concomitant
Skin Lesion Other Serious 4/1/2007 Male 7/27/2007 Physician Australia
Primary
Concomitant
Vomiting Other Serious 5/10/2007 57 Female 8/9/2007 Physician Japan
Primary
Secondary
Vomiting Other Serious 1/1/2006 Female 106 lb 8/10/2007 Physician Japan
Primary
Secondary
Concomitant
Vomiting Other Serious 5/10/2007 57 Female 8/16/2007 Physician Japan
Primary
Secondary
Pneumonia Hospitalization 2/18/2007 Male 97 lb 8/30/2007 Korea, Republic Of
Primary
Concomitant
Renal Failure Chronic Other Serious 1/1/2007 63 Male 143 lb 9/6/2007 Physician Japan
Primary
Concomitant
Rhabdomyolysis Life Threatening 6/1/2007 60 Male 212 lb 9/12/2007 Other Health Professional France
Primary
Secondary
Concomitant
Renal Impairment Other Serious 1/1/2006 54 Female 9/19/2007 Other Health Professional Italy
Primary
Concomitant
Interacting
Rash Other Serious 4/2/2007 71 Male 141 lb 9/17/2007 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 12/4/2006 71 Male 106 lb 9/18/2007 Physician Japan
Primary
Concomitant
Nephrogenic Systemic Fibrosis Death 1/1/2004 15 Male 77 lb 9/26/2007 Consumer United States
Primary
Secondary
Concomitant
Upper Gastrointestinal Haemorrhage Hospitalization 6/21/2007 Male 142 lb 9/21/2007 Other Health Professional United States
Primary
Concomitant
Skin Lesion Other Serious 4/1/2007 Male 10/1/2007 Physician Australia
Primary
Concomitant
Rash Other Serious 4/2/2007 71 Male 141 lb 10/10/2007 Physician Japan
Primary
Secondary
Concomitant
Stomatitis Other Serious 2/23/2007 63 Male 10/22/2007 Physician Japan
Primary
Concomitant
Tachycardia Life Threatening 6/22/2007 85 Female 132 lb 10/23/2007 Pharmacist United States
Primary
Secondary
Concomitant
Proteinuria Death 1/9/2007 Female 235 lb 11/7/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Death Death 10/1/2007 Male 183 lb 11/9/2007 Turkey
Primary
Concomitant
Renal Failure Chronic Other Serious 7/24/2007 63 Male 143 lb 11/13/2007 Physician Japan
Primary
Concomitant
Visual Disturbance 1/1/2002 57 Male 11/14/2007 Consumer United States
Primary
Concomitant
White Blood Cell Count Decreased Life Threatening 10/28/2007 14 Female 126 lb 11/12/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Staphylococcal Bacteraemia Life Threatening 10/7/2007 14 Male 203 lb 11/8/2007 Physician United States
Primary
Secondary
Concomitant
Vomiting Life Threatening 10/28/2007 14 Female 126 lb 11/21/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Proteinuria Death 1/1/2007 52 Female 235 lb 11/29/2007 Other Health Professional United Kingdom
Primary
Secondary
Interacting
Tachycardia Life Threatening 9/28/2007 21 Female 150 lb 11/21/2007 Consumer United States
Primary
Secondary
Concomitant
No Adverse Reaction 4/13/2003 Male 11/30/2007 Australia
Primary
Secondary
Concomitant
Proteinuria Death 1/9/2007 Female 235 lb 12/3/2007 Physician United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 12/4/2006 71 Male 106 lb 11/22/2007 Physician Japan
Primary
Concomitant
Unresponsive To Stimuli Life Threatening 9/28/2007 21 Female 150 lb 12/3/2007 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 12/8/2006 71 Male 106 lb 12/14/2007 Physician Japan
Primary
Concomitant
Toxic Skin Eruption Hospitalization 4/1/2007 Male 12/28/2007 Other Health Professional France
Primary
Secondary
Concomitant
Oedema Peripheral Other Serious 12/1/2007 Female 146 lb 1/18/2008 Other Health Professional United States
Primary
Concomitant
Oedema Peripheral Other Serious 12/1/2007 Female 146 lb 1/21/2008 Other Health Professional United States
Primary
Concomitant
Renal Failure Chronic Hospitalization 7/24/2007 63 Male 143 lb 2/1/2008 Physician Japan
Primary
Concomitant
Pyrexia Other Serious 12/8/2006 71 Male 106 lb 1/31/2008 Physician Japan
Primary
Concomitant
Rhabdomyolysis Life Threatening 6/1/2007 60 Male 212 lb 2/13/2008 Other Health Professional France
Primary
Secondary
Concomitant
Ventricular Fibrillation Death 1/15/2008 79 Male 212 lb 2/6/2008 Pharmacist United States
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 11/14/2006 58 Male 269 lb 2/18/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Other Serious 3/10/2007 74 Male 101 lb 2/22/2008 Physician Japan
Primary
Concomitant
Renal Failure Hospitalization 12/7/2004 Male 178 lb 3/3/2008 Physician United States
Primary
Concomitant
Raynaud's Phenomenon Other Serious 8/19/2005 61 Male 172 lb 3/4/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Life Threatening 6/30/2007 60 Male 212 lb 3/6/2008 Other Health Professional France
Primary
Secondary
Concomitant
Vomiting Other Serious 3/10/2007 74 Male 101 lb 3/4/2008 Physician Japan
Primary
Concomitant
Rhabdomyolysis Life Threatening 6/30/2007 60 Male 212 lb 3/14/2008 Other Health Professional France
Primary
Secondary
Concomitant
Rhabdomyolysis Life Threatening 6/1/2007 60 Male 212 lb 3/14/2008 Other Health Professional France
Primary
Secondary
Concomitant
Platelet Count Decreased Other Serious 8/21/2007 46 Female 121 lb 3/20/2008 Physician Japan
Primary
Concomitant
Rash Other Serious 4/2/2007 71 Male 141 lb 3/19/2008 Physician Japan
Primary
Secondary
Concomitant
Visual Acuity Reduced Other Serious 9/10/2007 58 Male 126 lb 3/28/2008 Physician Japan
Primary
Concomitant
Tumour Lysis Syndrome Other Serious 6/25/2007 55 Female 90 lb 3/31/2008 Physician Japan
Primary
Secondary
Concomitant
Stomatitis Other Serious 2/20/2007 63 Male 3/31/2008 Physician Japan
Primary
Concomitant
Renal Failure Other Serious 3/10/2007 74 Male 101 lb 4/10/2008 Physician Japan
Primary
Concomitant
Skin Lesion Other Serious 4/1/2007 Male 4/21/2008 Physician Australia
Primary
Concomitant
Gastrooesophageal Reflux Disease Hospitalization 5/11/2007 Male 205 lb 4/22/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 10/15/2005 69 Male 168 lb 4/25/2008 Physician Germany
Primary
Secondary
Concomitant
Nephrogenic Systemic Fibrosis Other Serious 1/1/2004 15 Male 77 lb 4/29/2008 Lawyer United States
Primary
Secondary
Concomitant
Nephrogenic Systemic Fibrosis Other Serious 1/1/2004 15 Male 77 lb 5/5/2008 Lawyer United States
Primary
Secondary
Concomitant
Nephrogenic Systemic Fibrosis Other Serious 1/1/2004 5/6/2008 Other Health Professional Germany
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 4/1/2008 28 Male 123 lb 5/6/2008 Physician United States
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 10/15/2005 68 Male 5/8/2008 Consumer United States
Primary
Secondary
Concomitant
Drug Interaction Other Serious 4/1/2007 47 Male 5/12/2008 Other Health Professional Italy
Primary
Secondary
Concomitant
Interacting
Toxic Skin Eruption Other Serious 4/1/2007 Male 5/12/2008 Other Health Professional France
Primary
Secondary
Concomitant
Erythropoiesis Abnormal Other Serious 47 Male 5/8/2008 Italy
Primary
Secondary
Concomitant
Chest Pain Life Threatening 5/8/2008 63 Male 5/14/2008 Sweden
Primary
Concomitant
Rectal Haemorrhage Hospitalization 4/14/2008 71 Male 5/15/2008 Physician Italy
Primary
Secondary
Concomitant
Renal Failure Other Serious 1/1/2007 45 Male 5/19/2008 Consumer United States
Primary
Concomitant
Platelet Count Decreased Death 1/19/2008 61 Male 123 lb 5/16/2008 Physician Japan
Primary
Concomitant
Rectal Haemorrhage Hospitalization 3/6/2008 80 Female 5/28/2008 Pharmacist United States
Primary
Concomitant
Impaired Work Ability Life Threatening 2/1/2008 63 Male 128 lb 6/5/2008 Sweden
Primary
Concomitant
Renal Failure Other Serious 1/1/2007 45 Male 6/3/2008 Physician United States
Primary
Concomitant
Platelet Count Decreased Death 1/19/2008 61 Male 123 lb 6/12/2008 Physician Japan
Primary
Concomitant
Xerosis Other Serious 1/1/2000 11 Male 77 lb 6/19/2008 Lawyer United States
Primary
Secondary
Concomitant
Xerosis Other Serious 1/1/2000 11 Male 77 lb 6/23/2008 Lawyer United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 1/4/2007 71 Female 126 lb 6/23/2008 Physician Japan
Primary
Secondary
Concomitant
Tumour Lysis Syndrome Other Serious 5/21/2008 71 Male 101 lb 6/26/2008 Physician Japan
Primary
Secondary
Concomitant
Urinary Retention Other Serious 1/4/2007 71 Female 126 lb 7/9/2008 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 4/1/2008 28 Male 123 lb 7/18/2008 Physician United States
Primary
Secondary
Concomitant
Renal Failure Chronic Other Serious 4/10/2008 Male 93 lb 7/22/2008 Physician Japan
Primary
Concomitant
Neoplasm Death 1/19/2008 61 Male 123 lb 7/15/2008 Physician Japan
Primary
Concomitant

Drug Data