Allopurinol combined with Peginterferon Alfa-2B

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Acute Psychosis Hospitalization 7/15/2007 Male 187 lb 7/20/2007 Physician United States
Primary
Secondary
Concomitant
Acute Psychosis Other Serious 7/15/2007 Male 187 lb 9/25/2007 Physician United States
Primary
Secondary
Concomitant
Erythema Other Serious 2/27/2012 58 Male 3/9/2012 Other Health Professional Japan
Primary
Concomitant
Oedema Other Serious 1/18/2012 65 Female 3/16/2012 Japan
Primary
Concomitant
Renal Failure Acute Other Serious 2/16/2012 59 Male 3/19/2012 Japan
Primary
Concomitant
Erythema Hospitalization 3/10/2012 64 Male 4/9/2012 Japan
Primary
Concomitant
Pyrexia Other Serious 2/27/2012 58 Male 4/19/2012 Japan
Primary
Concomitant
Malaise Hospitalization 4/9/2012 64 Female 4/20/2012 Japan
Primary
Concomitant
Fall Hospitalization 4/9/2012 4/23/2012 Physician Romania
Primary
Secondary
Concomitant
Appendicitis Hospitalization 4/18/2012 50 Male 182 lb 4/25/2012 Physician Japan
Primary
Secondary
Concomitant
Appendicitis Hospitalization 4/18/2012 50 Male 182 lb 4/27/2012 Physician Japan
Primary
Secondary
Concomitant
Hyperuricaemia Other Serious 2/16/2012 59 Male 5/3/2012 Other Health Professional Japan
Primary
Concomitant
Hypothyroidism Other Serious 1/18/2012 65 Female 5/3/2012 Other Health Professional Japan
Primary
Concomitant
Anaemia Other Serious 3/21/2012 67 Female 5/7/2012 Japan
Primary
Concomitant
Delirium Other Serious 3/9/2012 71 Female 5/7/2012 Japan
Primary
Concomitant
Renal Impairment Other Serious 3/26/2012 61 Male 5/7/2012 Other Health Professional Japan
Primary
Concomitant
Pneumonia Aspiration Hospitalization 4/18/2012 50 Male 182 lb 5/1/2012 Physician Japan
Primary
Secondary
Concomitant
Neutrophil Count Decreased Other Serious 2/1/2012 60 Male 5/8/2012 Japan
Primary
Concomitant
Renal Impairment 3/26/2012 61 Male 5/8/2012 Japan
Primary
Concomitant
Constipation Other Serious 3/5/2012 65 Male 115 lb 5/4/2012 Physician Japan
Primary
Secondary
Concomitant
Wound Complication Hospitalization 4/18/2012 50 Male 182 lb 5/4/2012 Physician Japan
Primary
Secondary
Concomitant
Anaemia Hospitalization 4/1/2012 61 Male 137 lb 5/4/2012 Physician Japan
Primary
Secondary
Concomitant
Intestinal Obstruction Hospitalization 4/18/2012 50 Male 182 lb 5/8/2012 Physician Japan
Primary
Secondary
Concomitant
Rash Other Serious 3/19/2012 64 Male 5/16/2012 Japan
Primary
Concomitant
Generalised Erythema Hospitalization 4/25/2012 45 Male 5/18/2012 Japan
Primary
Concomitant
Rash Hospitalization 3/9/2012 59 Male 5/23/2012 Japan
Primary
Concomitant
Hyperuricaemia Hospitalization 2/22/2012 66 Male 5/25/2012 Other Health Professional Japan
Primary
Concomitant
Renal Disorder Other Serious 3/23/2012 69 Male 5/25/2012 Japan
Primary
Concomitant
Blood Uric Acid Increased Hospitalization 1/23/2012 69 Female 104 lb 5/21/2012 Physician Japan
Primary
Secondary
Concomitant
Pyrexia Hospitalization 4/18/2012 50 Male 182 lb 5/14/2012 Physician Japan
Primary
Secondary
Concomitant
Hyperuricaemia Other Serious 2/9/2012 74 Male 5/30/2012 Japan
Primary
Concomitant
Loss Of Consciousness Other Serious 3/21/2012 67 Female 5/30/2012 Japan
Primary
Concomitant
Renal Disorder Other Serious 2/22/2012 66 Male 5/30/2012 Japan
Primary
Concomitant
Pyrexia Other Serious 4/10/2012 64 Male 152 lb 5/23/2012 Physician Japan
Primary
Secondary
Concomitant
Malaise Hospitalization Female 5/31/2012 Other Health Professional Japan
Primary
Concomitant
Renal Impairment Other Serious 2/20/2012 48 Male 5/31/2012 Japan
Primary
Concomitant
Erythema Hospitalization 4/18/2012 59 Male 6/3/2012 Other Health Professional Japan
Primary
Concomitant
Blood Creatine Phosphokinase Increased Hospitalization 5/23/2012 46 Male 6/3/2012 Other Health Professional Japan
Primary
Concomitant
Blood Creatinine Increased Hospitalization 3/21/2012 67 Female 6/4/2012 Japan
Primary
Concomitant
Renal Disorder Hospitalization 4/6/2012 61 Male 6/5/2012 Other Health Professional Japan
Primary
Concomitant
Pneumonia Hospitalization 5/5/2012 79 Male 6/7/2012 Other Health Professional Japan
Primary
Concomitant
Blood Uric Acid Increased Hospitalization 12/6/2011 69 Female 6/8/2012 Japan
Primary
Concomitant
Decreased Appetite Other Serious 5/18/2012 67 Female 6/11/2012 Japan
Primary
Concomitant
Blood Creatine Phosphokinase Increased Hospitalization 5/23/2012 46 Male 6/13/2012 Japan
Primary
Concomitant
Dizziness Other Serious 2/28/2012 63 Male 159 lb 6/5/2012 Physician Japan
Primary
Secondary
Concomitant
Retinal Haemorrhage Other Serious 5/29/2012 Male 6/20/2012 Japan
Primary
Concomitant
Neutrophil Count Decreased Other Serious 4/25/2012 51 Male 6/21/2012 Japan
Primary
Concomitant
Anaemia Other Serious 5/2/2012 68 Female 6/22/2012 Japan
Primary
Concomitant
Weight Decreased Other Serious 4/26/2012 67 Female 6/25/2012 Japan
Primary
Concomitant
Rash Other Serious 3/8/2012 68 Female 6/25/2012 Japan
Primary
Concomitant
Decreased Appetite Hospitalization 5/25/2012 60 Male 6/25/2012 Japan
Primary
Concomitant
Hyperuricaemia Other Serious 6/12/2012 68 Male 6/25/2012 Japan
Primary
Concomitant
Anaemia Other Serious 3/23/2012 69 Male 6/25/2012 Japan
Primary
Concomitant
Renal Disorder Other Serious 4/23/2012 60 Male 6/25/2012 Other Health Professional Japan
Primary
Concomitant
Delirium Other Serious 3/9/2012 71 Female 6/26/2012 Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 5/5/2012 46 Male 6/27/2012 Other Health Professional Japan
Primary
Concomitant
Blood Creatinine Increased Other Serious 3/12/2012 68 Male 6/29/2012 Other Health Professional Japan
Primary
Concomitant
Nausea Hospitalization 3/13/2012 45 Male 6/29/2012 Other Health Professional Japan
Primary
Concomitant
Anaemia Other Serious 3/12/2012 64 Female 6/29/2012 Other Health Professional Japan
Primary
Concomitant
Decreased Appetite Hospitalization 4/11/2012 70 Female 6/29/2012 Other Health Professional Japan
Primary
Concomitant
Substance-induced Psychotic Disorder Hospitalization 5/23/2012 46 Male 7/2/2012 Other Health Professional Japan
Primary
Concomitant
Herpes Zoster Other Serious 5/8/2012 65 Female 7/2/2012 Other Health Professional Japan
Primary
Concomitant
Renal Impairment Other Serious 2/20/2012 48 Male 7/5/2012 Other Health Professional Japan
Primary
Concomitant
Renal Impairment Other Serious 3/16/2012 61 Male 7/6/2012 Other Health Professional Japan
Primary
Concomitant
Rash Hospitalization 4/6/2012 61 Male 7/6/2012 Japan
Primary
Concomitant
Hyperuricaemia Other Serious 5/9/2012 59 Male 7/9/2012 Japan
Primary
Concomitant
Haemoglobin Decreased Hospitalization 4/26/2012 7/9/2012 Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 3/27/2012 39 Male 7/10/2012 Japan
Primary
Concomitant
Hyperuricaemia Other Serious 5/9/2012 70 Female 7/10/2012 Other Health Professional Japan
Primary
Concomitant
Decreased Appetite Hospitalization 4/12/2012 7/11/2012 Japan
Primary
Secondary
Concomitant
Sepsis Life Threatening 4/25/2012 64 Female 7/11/2012 Japan
Primary
Concomitant
Erythema Other Serious 6/1/2012 7/11/2012 Japan
Primary
Secondary
Concomitant
Retinopathy Other Serious 5/14/2012 68 Male 7/16/2012 Japan
Primary
Concomitant
Generalised Erythema Hospitalization 6/2/2012 63 Female 7/16/2012 Japan
Primary
Concomitant
Malaise Hospitalization 4/12/2012 7/17/2012 Japan
Primary
Secondary
Concomitant
Depression Other Serious 2/22/2012 66 Male 7/17/2012 Other Health Professional Japan
Primary
Concomitant
Anaemia Hospitalization 3/21/2012 67 Female 7/17/2012 Other Health Professional Japan
Primary
Concomitant
Rash Hospitalization 1/21/2012 7/19/2012 Physician Japan
Primary
Secondary
Concomitant
Delirium Other Serious 3/9/2012 71 Female 7/19/2012 Japan
Primary
Concomitant
Erythema Multiforme Hospitalization 6/12/2012 68 Male 7/19/2012 Other Health Professional Japan
Primary
Concomitant
Anaemia Other Serious 5/1/2012 72 Male 7/19/2012 Other Health Professional Japan
Primary
Concomitant
Erythema Multiforme Hospitalization 6/24/2012 60 Male 7/23/2012 Other Health Professional Japan
Primary
Concomitant
Neutrophil Count Decreased Other Serious 6/19/2012 62 Male 7/23/2012 Japan
Primary
Concomitant
Blood Creatinine Increased Other Serious 6/29/2012 66 Male 7/23/2012 Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 4/21/2012 63 Male 7/23/2012 Japan
Primary
Concomitant
Anaemia Hospitalization 5/26/2012 59 Male 7/23/2012 Other Health Professional Japan
Primary
Concomitant
Rash Other Serious 54 Male 7/23/2012 Japan
Primary
Concomitant
Renal Impairment Other Serious 5/16/2012 47 Male 7/25/2012 Japan
Primary
Concomitant
Blood Creatinine Increased Hospitalization 6/1/2012 50 Male 7/26/2012 Japan
Primary
Concomitant
Rash Other Serious 4/20/2012 55 Male 7/30/2012 Other Health Professional Japan
Primary
Concomitant
Erythema Annulare Hospitalization 5/29/2012 67 Male 7/30/2012 Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 4/20/2012 55 Female 7/31/2012 Japan
Primary
Concomitant
Retinopathy Other Serious 6/30/2012 68 Female 7/31/2012 Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 2/15/2012 56 Female 7/31/2012 Japan
Primary
Concomitant
Retinal Haemorrhage Other Serious 5/29/2012 Male 8/1/2012 Japan
Primary
Concomitant
Decreased Appetite Other Serious 5/2/2012 68 Female 8/2/2012 Japan
Primary
Concomitant
Decreased Appetite Hospitalization 5/25/2012 60 Male 8/2/2012 Japan
Primary
Concomitant
Pancreatitis Acute Hospitalization 6/22/2012 61 Male 8/2/2012 Other Health Professional Japan
Primary
Concomitant
Erythema Other Serious 6/13/2012 46 Male 8/2/2012 Japan
Primary
Concomitant
Drug Eruption Hospitalization 5/29/2012 67 Male 8/2/2012 Other Health Professional Japan
Primary
Concomitant
Bone Marrow Failure Other Serious 6/5/2012 35 Female 8/2/2012 Other Health Professional Japan
Primary
Concomitant
Ascites Hospitalization 7/17/2012 68 Female 8/6/2012 Japan
Primary
Concomitant
Anaemia Other Serious 3/12/2012 64 Female 8/6/2012 Other Health Professional Japan
Primary
Concomitant
Haemoglobin Decreased Hospitalization 1/20/2012 8/7/2012 Physician Japan
Primary
Secondary
Concomitant
Dizziness Hospitalization 6/23/2012 61 Female 8/9/2012 Japan
Primary
Concomitant
Dizziness Hospitalization 6/23/2012 61 Female 8/9/2012 Japan
Primary
Concomitant
Drug Eruption Hospitalization 5/29/2012 67 Male 8/9/2012 Japan
Primary
Concomitant
Erythema Other Serious 6/1/2012 8/8/2012 Japan
Primary
Secondary
Concomitant
Stomatitis Hospitalization 1/21/2012 8/9/2012 Physician Japan
Primary
Secondary
Concomitant
Neutrophil Count Decreased Hospitalization 2/24/2012 8/9/2012 Japan
Primary
Secondary
Concomitant
Agranulocytosis Other Serious 63 Male 8/10/2012 Other Health Professional Japan
Primary
Concomitant
Scrotal Haematocoele Other Serious 6/20/2012 69 Male 8/10/2012 Japan
Primary
Concomitant
Renal Impairment Other Serious 5/1/2012 61 Male 8/10/2012 Japan
Primary
Concomitant
Urinary Tract Infection Hospitalization 7/22/2012 51 Male 8/10/2012 Japan
Primary
Concomitant
Renal Impairment Hospitalization 6/13/2012 61 Female 8/10/2012 Japan
Primary
Concomitant
Decreased Appetite Other Serious 4/26/2012 67 Female 8/10/2012 Japan
Primary
Concomitant
Rash Other Serious 6/25/2012 65 Female 8/13/2012 Other Health Professional Japan
Primary
Concomitant
Renal Impairment Other Serious 5/8/2012 65 Female 8/13/2012 Japan
Primary
Concomitant
Decreased Appetite Hospitalization 4/11/2012 70 Female 8/13/2012 Other Health Professional Japan
Primary
Concomitant
Renal Failure Acute Other Serious 6/25/2012 60 Male 8/14/2012 Japan
Primary
Concomitant
Haemoglobin Decreased Other Serious 1/28/2012 8/14/2012 Consumer Japan
Primary
Secondary
Concomitant
Pancreatitis Hospitalization 6/22/2012 61 Male 8/14/2012 Japan
Primary
Concomitant
Hyperuricaemia Other Serious 5/9/2012 59 Male 8/14/2012 Other Health Professional Japan
Primary
Concomitant
Anaemia Other Serious 3/12/2012 8/15/2012 Consumer Japan
Primary
Secondary
Concomitant
Hypoglycaemia Other Serious 6/29/2012 56 Male 8/22/2012 Other Health Professional Japan
Primary
Concomitant
Haemoglobin Decreased Hospitalization 6/8/2012 71 Female 8/22/2012 Other Health Professional Japan
Primary
Concomitant
Decreased Appetite Other Serious 5/2/2012 8/21/2012 Consumer Japan
Primary
Secondary
Concomitant
Drug Eruption Other Serious 3/29/2012 8/22/2012 Physician Japan
Primary
Secondary
Concomitant
Toxic Skin Eruption Other Serious 4/12/2012 8/16/2012 Consumer Japan
Primary
Secondary
Concomitant
Urinary Bladder Haemorrhage Hospitalization 4/1/2012 8/16/2012 Consumer Japan
Primary
Secondary
Concomitant
Renal Disorder Other Serious 2/17/2012 61 Male 8/27/2012 Other Health Professional Japan
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 6/27/2012 40 Male 8/27/2012 Other Health Professional Japan
Primary
Concomitant
Blood Uric Acid Increased 4/20/2012 10/23/2012 Consumer Jp
Primary
Secondary
Concomitant
Hypoglycaemia Other Serious 6/29/2012 56 Male 11/28/2012 Other Health Professional Jp
Primary
Secondary
Concomitant
Retinopathy Other Serious 3/9/2012 71 Female 12/21/2012 Other Health Professional Jp
Primary
Secondary
Concomitant
Sepsis Other Serious 8/21/2012 65 Female 9/17/2012 Other Health Professional Jp
Primary
Concomitant
Skin Disorder Other Serious 9/4/2012 57 Male 11/21/2012 Other Health Professional Jp
Primary
Concomitant
Pancreatitis Acute Hospitalization 7/9/2012 46 Female 10/10/2012 Other Health Professional Jp
Primary
Secondary
Concomitant
Drug Eruption Other Serious 8/18/2012 49 Male 10/9/2012 Other Health Professional Jp
Primary
Concomitant
Neutrophil Count Decreased Other Serious 4/25/2012 51 Male 10/18/2012 Other Health Professional Jp
Primary
Secondary
Concomitant
Neutrophil Count Decreased Other Serious 7/30/2012 72 Male 12/12/2012 Other Health Professional Jp
Primary
Secondary
Concomitant
Decreased Appetite Hospitalization 5/25/2012 60 Male 10/26/2012 Other Health Professional Jp
Primary
Secondary
Concomitant
Rash Hospitalization 10/1/2012 63 Female 12/26/2012 Other Health Professional Jp
Primary
Secondary
Concomitant
Ventricular Tachycardia Hospitalization 3/30/2010 76 Male 185 lb 11/29/2012 Physician Be
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 9/10/2012 54 Female 11/21/2012 Other Health Professional Jp
Primary
Secondary
Concomitant
Anaemia Other Serious 4/3/2012 63 Male 154 lb 11/21/2012 Consumer Jp
Primary
Secondary
Concomitant
Neutrophil Count Decreased Other Serious 4/19/2012 62 Female 11/30/2012 Other Health Professional Jp
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 2/6/2012 57 Male 12/21/2012 Other Health Professional Jp
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 9/10/2012 62 Male 12/28/2012 Other Health Professional Jp
Primary
Secondary
Concomitant
Loss Of Consciousness Other Serious 12/4/2012 65 Male 12/31/2012 Other Health Professional Jp
Primary
Secondary
Concomitant

Drug Data