Allopurinol combined with Peg-Intron

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Drug Toxicity Death 12/11/2005 49 Male 210 lb 5/2/2006 Physician United States
Primary
Secondary
Concomitant
Stomatitis Other Serious 71 Male 5/30/2006 Consumer Germany
Primary
Concomitant
Sepsis Other Serious 3/12/2002 57 Male 168 lb 6/13/2006 Physician Spain
Primary
Concomitant
Motor Dysfunction Other Serious 4/29/2006 59 Male 121 lb 6/14/2006 Physician Japan
Primary
Secondary
Concomitant
Leukopenia Other Serious 7/5/1999 Male 7/6/2006 Physician Japan
Primary
Secondary
Concomitant
Wheezing Death 11/17/2006 57 Male 143 lb 12/22/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Systemic Inflammatory Response Syndrome Hospitalization 11/3/2006 57 Male 143 lb 1/2/2007 Other Health Professional Japan
Primary
Secondary
Concomitant
Hepatic Steatosis Hospitalization 7/1/2006 61 Male 154 lb 4/12/2007 Physician Japan
Primary
Secondary
Concomitant
Swelling Hospitalization 3/13/2007 67 Male 128 lb 5/14/2007 Physician Japan
Primary
Secondary
Concomitant
Red Blood Cell Count Decreased Hospitalization 7/1/2006 61 Male 154 lb 6/6/2007 Physician Japan
Primary
Secondary
Concomitant
Swelling Hospitalization 3/14/2007 67 Male 128 lb 6/13/2007 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 8/11/2005 47 Male 172 lb 6/18/2007 Physician Japan
Primary
Secondary
Concomitant
Blood Bilirubin Increased Life Threatening 7/3/2007 Male 256 lb 7/16/2007 Physician United States
Primary
Secondary
Concomitant
Vomiting Life Threatening 7/3/2007 57 Male 7/19/2007 Physician United States
Primary
Secondary
Concomitant
Blood Bilirubin Increased Life Threatening 7/3/2007 Male 256 lb 8/1/2007 Physician United States
Primary
Secondary
Concomitant
Vomiting Life Threatening 7/3/2007 57 Male 8/3/2007 Physician United States
Primary
Secondary
Concomitant
Vomiting Other Serious 7/3/2007 Male 256 lb 8/9/2007 Physician United States
Primary
Secondary
Concomitant
Vomiting Disability 7/3/2007 57 Male 8/13/2007 Physician United States
Primary
Secondary
Concomitant
Blood Bilirubin Increased Other Serious 7/3/2007 Male 256 lb 8/21/2007 Physician United States
Primary
Secondary
Concomitant
Vomiting Other Serious 7/3/2007 Male 256 lb 8/27/2007 Physician United States
Primary
Secondary
Concomitant
Vomiting Disability 7/3/2007 57 Male 8/23/2007 Physician United States
Primary
Secondary
Concomitant
Blood Bilirubin Increased Other Serious 7/3/2007 Male 256 lb 9/4/2007 Physician United States
Primary
Secondary
Concomitant
Vomiting Disability 7/3/2007 57 Male 8/30/2007 Physician United States
Primary
Secondary
Concomitant
Blood Bilirubin Increased Other Serious 7/3/2007 Male 256 lb 9/10/2007 Physician United States
Primary
Secondary
Concomitant
Vomiting Disability 7/3/2007 57 Male 9/5/2007 Physician United States
Primary
Secondary
Concomitant
Vomiting Disability 7/3/2007 57 Male 9/12/2007 Physician United States
Primary
Secondary
Concomitant
Blood Bilirubin Increased Other Serious 7/3/2007 Male 256 lb 9/18/2007 Physician United States
Primary
Secondary
Concomitant
Hypoalbuminaemia Other Serious 9/14/2006 62 Male 161 lb 9/14/2007 Physician Japan
Primary
Secondary
Concomitant
Blood Bilirubin Increased Other Serious 7/3/2007 Male 256 lb 9/24/2007 Physician United States
Primary
Secondary
Concomitant
Vomiting Disability 7/3/2007 57 Male 9/19/2007 Physician United States
Primary
Secondary
Concomitant
Vomiting Disability 7/3/2007 57 Male 9/25/2007 Physician United States
Primary
Secondary
Concomitant
Blood Bilirubin Increased Other Serious 7/3/2007 Male 256 lb 10/1/2007 Physician United States
Primary
Secondary
Concomitant
Blood Bilirubin Increased Other Serious 7/3/2007 Male 256 lb 10/8/2007 Physician United States
Primary
Secondary
Concomitant
Vomiting Disability 7/3/2007 57 Male 10/9/2007 Physician United States
Primary
Secondary
Concomitant
Blood Bilirubin Increased Other Serious 7/3/2007 Male 256 lb 10/15/2007 Physician United States
Primary
Secondary
Concomitant
Blood Bilirubin Increased Other Serious 7/3/2007 Male 256 lb 10/22/2007 Physician United States
Primary
Secondary
Concomitant
Vomiting Disability 7/3/2007 57 Male 10/17/2007 Physician United States
Primary
Secondary
Concomitant
Vomiting Disability 7/3/2007 57 Male 10/23/2007 Physician United States
Primary
Secondary
Concomitant
Blood Bilirubin Increased Other Serious 7/3/2007 Male 256 lb 10/29/2007 Physician United States
Primary
Secondary
Concomitant
Blood Bilirubin Increased Other Serious 7/3/2007 Male 256 lb 11/5/2007 Physician United States
Primary
Secondary
Concomitant
Blood Bilirubin Increased Other Serious 7/3/2007 Male 256 lb 11/12/2007 Physician United States
Primary
Secondary
Concomitant
Blood Bilirubin Increased Other Serious 7/3/2007 Male 256 lb 11/19/2007 Physician United States
Primary
Secondary
Concomitant
Blood Bilirubin Increased Other Serious 7/3/2007 Male 256 lb 11/27/2007 Physician United States
Primary
Secondary
Concomitant
Blood Bilirubin Increased Other Serious 7/3/2007 Male 256 lb 12/5/2007 Physician United States
Primary
Secondary
Concomitant
Blood Bilirubin Increased Other Serious 7/3/2007 Male 256 lb 12/18/2007 Physician United States
Primary
Secondary
Concomitant
Vomiting Disability 7/3/2007 57 Male 12/19/2007 Physician United States
Primary
Secondary
Concomitant
Blood Bilirubin Increased Other Serious 7/3/2007 Male 256 lb 1/21/2008 Physician United States
Primary
Secondary
Concomitant
Blood Bilirubin Increased Other Serious 7/3/2007 Male 256 lb 1/29/2008 Physician United States
Primary
Secondary
Concomitant
Blood Bilirubin Increased Other Serious 7/3/2007 Male 256 lb 2/20/2008 Physician United States
Primary
Secondary
Concomitant
Vomiting Disability 7/3/2007 57 Male 2/21/2008 Physician United States
Primary
Secondary
Concomitant
Tremor Other Serious 7/3/2007 Male 256 lb 3/13/2008 Physician United States
Primary
Secondary
Concomitant
Vomiting Disability 7/3/2007 57 Male 3/17/2008 Physician United States
Primary
Secondary
Concomitant
Therapeutic Response Decreased Other Serious 8/29/2007 5/29/2008 Other Health Professional United Kingdom
Primary
Concomitant
Swelling Hospitalization 3/14/2007 67 Male 128 lb 6/2/2008 Physician Japan
Primary
Secondary
Concomitant
Neutrophil Count Increased Hospitalization 3/14/2007 67 Male 128 lb 6/4/2008 Physician Japan
Primary
Secondary
Concomitant
Blood Bilirubin Increased Other Serious 7/3/2007 Male 184 lb 8/13/2008 Physician United States
Primary
Secondary
Concomitant
Vomiting Disability 7/3/2007 57 Male 8/15/2008 Physician United States
Primary
Secondary
Concomitant
Lung Neoplasm Malignant Other Serious 6/1/2008 55 Female 9/25/2008 United States
Primary
Secondary
Concomitant
Weight Increased Hospitalization 8/18/2008 60 Male 166 lb 10/14/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Cytolytic Hepatitis Hospitalization 1/1/2010 71 Female 134 lb 2/19/2010 Physician France
Primary
Secondary
Concomitant
Jaundice Cholestatic Hospitalization 1/1/2010 71 Female 134 lb 3/11/2010 Physician France
Primary
Secondary
Concomitant
Splenomegaly Hospitalization 1/1/2010 71 Female 134 lb 3/15/2010 Physician France
Primary
Secondary
Concomitant
Lactic Acidosis Other Serious Female 11/12/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Diarrhoea Hospitalization 63 Male 4/13/2011 Other Health Professional Korea, Republic Of
Primary
Secondary
Concomitant
Inappropriate Antidiuretic Hormone Secretion Hospitalization 6/22/2011 61 Male 123 lb 11/14/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Platelet Count Decreased Other Serious 1/12/2012 55 Male 2/7/2012 Consumer Japan
Primary
Concomitant
Renal Impairment Other Serious 12/22/2011 45 Male 2/21/2012 Other Health Professional Japan
Primary
Concomitant
Pyrexia Hospitalization 1/25/2012 55 Male 3/14/2012 Japan
Primary
Concomitant
Anaemia Death 3/3/2012 45 Male 254 lb 3/14/2012 Physician Germany
Primary
Secondary
Concomitant
Decreased Appetite Hospitalization 2/14/2012 73 Female 4/9/2012 Other Health Professional Japan
Primary
Concomitant
Blood Creatinine Increased Other Serious 2/13/2012 62 Male 4/15/2012 Japan
Primary
Concomitant
Rash Other Serious 3/1/2012 60 Male 4/20/2012 Other Health Professional Japan
Primary
Concomitant
Urinary Bladder Haemorrhage Hospitalization 4/1/2012 61 Male 4/23/2012 Japan
Primary
Concomitant
Renal Disorder Other Serious 2/24/2012 60 Male 4/24/2012 Other Health Professional Japan
Primary
Concomitant
Drug Eruption Hospitalization 4/5/2012 72 Male 4/24/2012 Other Health Professional Japan
Primary
Concomitant
Hyperuricaemia Other Serious 3/3/2012 65 Male 4/26/2012 Japan
Primary
Concomitant
Haemoglobin Decreased Other Serious 3/9/2012 51 Male 4/26/2012 Japan
Primary
Concomitant
C-reactive Protein Increased Hospitalization 3/5/2012 58 Female 86 lb 4/24/2012 Physician Japan
Primary
Secondary
Concomitant
Duodenal Ulcer Hospitalization 3/17/2012 62 Male 141 lb 4/24/2012 Physician Japan
Primary
Secondary
Concomitant
Haemoglobin Decreased Hospitalization 4/5/2012 72 Male 5/1/2012 Japan
Primary
Concomitant
Neutrophil Count Decreased Other Serious 3/9/2012 51 Male 5/1/2012 Japan
Primary
Concomitant
Rash Other Serious 1/22/2012 59 Male 5/2/2012 Other Health Professional Japan
Primary
Concomitant
Blood Creatinine Increased Hospitalization 2/7/2012 65 Female 5/2/2012 Japan
Primary
Concomitant
Depressive Symptom Other Serious 2/13/2012 62 Male 5/2/2012 Other Health Professional Japan
Primary
Concomitant
Rash Hospitalization 1/21/2012 65 Male 5/3/2012 Other Health Professional Japan
Primary
Concomitant
Hyperuricaemia Other Serious 2/16/2012 59 Male 5/4/2012 Japan
Primary
Concomitant
Eosinophil Count Increased Hospitalization 1/21/2012 65 Male 5/4/2012 Japan
Primary
Concomitant
Mania Other Serious 4/1/2012 60 Female 5/7/2012 Japan
Primary
Concomitant
Pyrexia Other Serious 1/25/2012 55 Male 5/7/2012 Japan
Primary
Concomitant
Hepatic Function Abnormal Hospitalization 4/17/2012 68 Male 5/7/2012 Other Health Professional Japan
Primary
Concomitant
Rash Other Serious 3/1/2012 51 Male 5/8/2012 Other Health Professional Japan
Primary
Concomitant
Drug Eruption Hospitalization 4/5/2012 72 Male 5/8/2012 Other Health Professional Japan
Primary
Concomitant
Neutropenia Other Serious 2/23/2012 54 Male 5/8/2012 Other Health Professional Japan
Primary
Concomitant
Liver Disorder Other Serious 4/17/2012 68 Male 5/8/2012 Other Health Professional Japan
Primary
Concomitant
Neutropenia Hospitalization 2/23/2012 54 Male 5/9/2012 Japan
Primary
Concomitant
Hyperuricaemia Other Serious 3/7/2012 60 Male 115 lb 5/4/2012 Physician Japan
Primary
Secondary
Concomitant
Duodenal Ulcer Other Serious 2/13/2012 62 Male 5/10/2012 Other Health Professional Japan
Primary
Concomitant
Neutrophil Count Decreased Other Serious 2/1/2012 60 Male 5/11/2012 Japan
Primary
Concomitant
Renal Impairment Other Serious 3/13/2012 72 Male 5/14/2012 Japan
Primary
Concomitant
Retinal Haemorrhage Other Serious 2/16/2012 51 Male 5/16/2012 Other Health Professional Japan
Primary
Concomitant
Decreased Appetite Hospitalization 2/14/2012 73 Female 5/18/2012 Japan
Primary
Concomitant
Rash Hospitalization 2/9/2012 64 Male 5/22/2012 Japan
Primary
Concomitant
Renal Failure Acute Hospitalization 2/16/2012 59 Male 5/22/2012 Other Health Professional Japan
Primary
Concomitant
Blood Creatinine Increased Hospitalization 3/16/2012 62 Male 5/24/2012 Other Health Professional Japan
Primary
Concomitant
Blood Creatinine Increased Hospitalization 2/23/2012 50 Female 5/24/2012 Other Health Professional Japan
Primary
Concomitant
Depression Hospitalization 2/13/2012 62 Male 5/25/2012 Japan
Primary
Concomitant
Hyperuricaemia Other Serious 2/16/2012 59 Male 5/25/2012 Japan
Primary
Concomitant
Renal Disorder Other Serious 2/17/2012 61 Male 5/29/2012 Japan
Primary
Concomitant
Hyperuricaemia Hospitalization 47 Male 154 lb 5/16/2012 Physician Japan
Primary
Secondary
Concomitant
Renal Impairment Hospitalization Male 5/31/2012 Other Health Professional Japan
Primary
Concomitant
Nausea Hospitalization 4/1/2012 61 Male 6/1/2012 Japan
Primary
Concomitant
Gastritis Hospitalization 5/10/2012 66 Male 6/1/2012 Japan
Primary
Concomitant
Drug Eruption Other Serious 5/11/2012 58 Male 6/1/2012 Other Health Professional Japan
Primary
Concomitant
Anaemia Other Serious 4/20/2012 69 Male 6/1/2012 Other Health Professional Japan
Primary
Concomitant
Gastritis Hospitalization 3/26/2012 66 Male 6/6/2012 Other Health Professional Japan
Primary
Concomitant
Anaemia Hospitalization 2/14/2012 73 Female 6/8/2012 Japan
Primary
Concomitant
Renal Impairment Other Serious 3/13/2012 60 Male 6/11/2012 Japan
Primary
Concomitant
Renal Impairment Hospitalization 5/21/2012 49 Male 6/11/2012 Japan
Primary
Concomitant
Gait Disturbance Other Serious 2/28/2012 63 Male 159 lb 5/31/2012 Physician Japan
Primary
Secondary
Concomitant
Oral Mucosa Erosion Hospitalization 4/25/2012 45 Male 163 lb 5/30/2012 Physician Japan
Primary
Secondary
Concomitant
Neutrophil Count Decreased Other Serious 3/9/2012 51 Male 6/11/2012 Japan
Primary
Concomitant
Drug Eruption Other Serious 3/29/2012 62 Male 6/14/2012 Other Health Professional Japan
Primary
Concomitant
Hyperuricaemia Other Serious 2/9/2012 74 Male 141 lb 6/7/2012 Physician Japan
Primary
Secondary
Concomitant
Nausea Other Serious 4/24/2012 63 Female 99 lb 6/5/2012 Physician Japan
Primary
Secondary
Concomitant
Rash Hospitalization 5/10/2012 66 Male 168 lb 6/8/2012 Physician Japan
Primary
Secondary
Concomitant
Anaemia Life Threatening 4/17/2012 53 Male 6/20/2012 Japan
Primary
Concomitant
Hyperuricaemia Hospitalization 5/15/2012 51 Male 269 lb 6/13/2012 Physician Japan
Primary
Secondary
Concomitant
Retinal Haemorrhage Other Serious 46 Male 6/21/2012 Japan
Primary
Concomitant
Urinary Bladder Haemorrhage Hospitalization 4/1/2012 61 Male 137 lb 6/12/2012 Physician Japan
Primary
Secondary
Concomitant
Blood Uric Acid Increased Hospitalization 4/18/2012 59 Male 132 lb 6/12/2012 Physician Japan
Primary
Secondary
Concomitant
Blood Creatine Phosphokinase Increased Hospitalization 5/23/2012 46 Male 179 lb 6/12/2012 Physician Japan
Primary
Secondary
Concomitant
Pyrexia Other Serious 5/21/2012 67 Female 132 lb 6/12/2012 Physician Japan
Primary
Secondary
Concomitant
Blood Creatinine Increased Hospitalization 3/16/2012 62 Male 6/26/2012 Other Health Professional Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 5/22/2012 60 Male 141 lb 6/20/2012 Physician Japan
Primary
Secondary
Concomitant
Pruritus Hospitalization 5/2/2012 66 Male 168 lb 6/15/2012 Physician Japan
Primary
Secondary
Concomitant
Hyperuricaemia Other Serious 3/26/2012 60 Female 6/29/2012 Other Health Professional Japan
Primary
Concomitant
Rash Other Serious 1/22/2012 59 Male 6/29/2012 Other Health Professional Japan
Primary
Concomitant
Stomatitis Hospitalization 1/21/2012 65 Male 7/3/2012 Japan
Primary
Concomitant
Rash Other Serious 5/30/2012 50 Female 7/3/2012 Other Health Professional Japan
Primary
Concomitant
Renal Impairment Other Serious 12/22/2011 45 Male 7/3/2012 Japan
Primary
Concomitant
Retinal Haemorrhage Other Serious 6/11/2012 46 Male 7/5/2012 Japan
Primary
Concomitant
Skin Disorder Other Serious 6/1/2012 51 Male 7/5/2012 Japan
Primary
Concomitant
Pyrexia Other Serious 5/17/2012 58 Male 134 lb 6/25/2012 Physician Japan
Primary
Secondary
Concomitant
Neutrophil Count Decreased Other Serious 1/19/2012 47 Male 7/5/2012 Other Health Professional Japan
Primary
Concomitant
Off Label Use Other Serious 5/11/2012 62 Male 7/5/2012 Japan
Primary
Concomitant
Platelet Count Decreased Other Serious 2/29/2012 64 Male 7/6/2012 Japan
Primary
Concomitant
Renal Impairment Hospitalization Male 7/6/2012 Japan
Primary
Concomitant
Depression Hospitalization 5/23/2012 46 Male 179 lb 6/27/2012 Physician Japan
Primary
Secondary
Concomitant
Hyperuricaemia Hospitalization 5/27/2012 64 Female 115 lb 6/27/2012 Physician Japan
Primary
Secondary
Concomitant
Renal Impairment Other Serious 4/23/2012 59 Male 7/9/2012 Other Health Professional Japan
Primary
Concomitant

Drug Data