Allopurinol combined with Oxaliplatin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Peripheral Sensory Neuropathy Life Threatening 1/1/2006 Male 4/29/2006 Physician United States
Primary
Concomitant
Peripheral Sensory Neuropathy Life Threatening 1/1/2006 Male 4/29/2006 Physician United States
Primary
Concomitant
Sepsis Life Threatening 1/2/2006 Male 6/2/2006 Physician France
Primary
Secondary
Concomitant
Sepsis Life Threatening 1/2/2006 Male 6/28/2006 Physician France
Primary
Secondary
Concomitant
Tumour Lysis Syndrome Hospitalization 7/10/2006 Male 140 lb 7/27/2006 Other Health Professional United States
Primary
Concomitant
Supraventricular Tachycardia Hospitalization 7/10/2006 Male 153 lb 8/8/2006 Other Health Professional Australia
Primary
Secondary
Concomitant
Supraventricular Tachycardia Hospitalization 7/8/2006 Male 153 lb 9/7/2006 Other Health Professional Australia
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 7/8/2006 Male 153 lb 9/8/2006 Other Health Professional Australia
Primary
Secondary
Concomitant
Somnolence Life Threatening 10/1/2006 68 Male 124 lb 11/20/2006 Physician New Zealand
Primary
Secondary
Concomitant
Pyrexia Hospitalization 3/31/2006 76 Female 150 lb 11/13/2006 Other Health Professional Germany
Primary
Secondary
Concomitant
Wound Dehiscence Life Threatening 10/1/2006 68 Male 147 lb 11/30/2006 Physician New Zealand
Primary
Secondary
Concomitant
Somnolence Hospitalization 11/7/2006 68 Male 124 lb 11/21/2006 Physician New Zealand
Primary
Secondary
Concomitant
Wound Dehiscence Hospitalization 11/7/2006 68 Male 147 lb 12/5/2006 Physician New Zealand
Primary
Secondary
Concomitant
Gastroenteritis Hospitalization 6/10/2006 50 Male 126 lb 12/18/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 6/10/2006 50 Male 126 lb 1/2/2007 Physician Japan
Primary
Secondary
Concomitant
Wound Dehiscence Hospitalization 11/7/2006 68 Male 147 lb 1/30/2007 Physician New Zealand
Primary
Secondary
Concomitant
Somnolence Hospitalization 11/7/2006 68 Male 124 lb 11/21/2006 Other Health Professional New Zealand
Primary
Secondary
Concomitant
Performance Status Decreased Other Serious 10/24/2006 Male 3/21/2007 Physician Austria
Primary
Secondary
Concomitant
Resuscitation Other Serious 10/24/2006 Male 3/29/2007 Physician Austria
Primary
Secondary
Concomitant
Small Intestinal Obstruction Hospitalization 2/1/2007 65 Male 222 lb 4/2/2007 Physician United States
Primary
Secondary
Concomitant
Resuscitation Other Serious 10/24/2006 Male 4/6/2007 Physician Austria
Primary
Secondary
Concomitant
Diarrhoea Hospitalization 3/24/2007 77 Male 236 lb 6/5/2007 Consumer United States
Primary
Secondary
Concomitant
Epilepsy Other Serious 5/28/2007 Male 216 lb 6/25/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 5/28/2007 Male 216 lb 7/6/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Resuscitation Other Serious 10/24/2006 Male 7/23/2007 Physician Austria
Primary
Secondary
Concomitant
Epilepsy Hospitalization 5/28/2007 Male 216 lb 7/23/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Gastric Ulcer Other Serious 5/11/2005 Male 88 lb 9/14/2007 Other Health Professional Japan
Primary
Secondary
Concomitant
Hepatic Encephalopathy Life Threatening 6/23/2007 Female 128 lb 9/14/2007 Physician Japan
Primary
Secondary
Concomitant
Pyrexia Other Serious 9/30/2007 Female 10/19/2007 Consumer France
Primary
Secondary
Concomitant
Febrile Neutropenia Other Serious 8/23/2006 76 Female 11/27/2006 Other Health Professional United States
Primary
Concomitant
Febrile Neutropenia Other Serious 8/18/2006 64 Female 11/27/2006 Physician United States
Primary
Concomitant
Resuscitation Other Serious 10/24/2006 Male 11/7/2007 Physician Austria
Primary
Secondary
Concomitant
Leukocytoclastic Vasculitis Hospitalization 12/9/2007 Male 172 lb 12/12/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Purpura Hospitalization 12/9/2007 72 Male 172 lb 12/20/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Purpura Hospitalization 12/9/2007 72 Male 172 lb 12/31/2007 Other Health Professional United States
Primary
Secondary
Purpura Hospitalization 12/9/2007 Male 78 lb 1/11/2008 Consumer United States
Primary
Secondary
Purpura Hospitalization 12/9/2007 72 Male 172 lb 1/14/2008 Other Health Professional United States
Primary
Secondary
Purpura Hospitalization 12/9/2007 Male 78 lb 1/13/2008 Physician United States
Primary
Secondary
Concomitant
Myocardial Infarction Life Threatening 9/16/2007 71 Male 216 lb 1/21/2008 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Leukocytoclastic Vasculitis Hospitalization 12/9/2007 72 Male 78 lb 1/16/2008 Physician United States
Primary
Secondary
Purpura Hospitalization 12/9/2007 72 Male 78 lb 1/17/2008 United States
Primary
Secondary
Purpura Hospitalization 12/9/2007 72 Male 172 lb 2/1/2008 Consumer United States
Primary
Secondary
Purpura Hospitalization 12/6/2007 Male 78 lb 2/1/2008 Consumer United States
Primary
Secondary
Performance Status Decreased Other Serious 10/24/2006 Male 3/6/2008 Physician Austria
Primary
Secondary
Concomitant
Pulmonary Hypertension Life Threatening 11/16/2007 Male 4/24/2008 France
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 2/14/2008 Male 220 lb 4/25/2008 Physician Switzerland
Primary
Concomitant
Pulmonary Arterial Hypertension Life Threatening 11/16/2007 Male 5/14/2008 Other Health Professional France
Primary
Secondary
Concomitant
Pancreatitis Acute Hospitalization 5/14/2008 Male 7/23/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Fatigue Hospitalization 2/14/2008 Male 220 lb 7/29/2008 Physician Switzerland
Primary
Concomitant
Renal Failure Hospitalization 6/5/2008 Female 8/18/2008 Physician Poland
Primary
Concomitant
Ultrasound Scan Abnormal Hospitalization 6/18/2008 Male 8/20/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Renal Failure Hospitalization 6/5/2008 Female 9/5/2008 Physician Poland
Primary
Concomitant
Renal Failure Hospitalization 6/5/2008 Female 9/16/2008 Physician Poland
Primary
Concomitant
Urinary Retention Hospitalization 9/1/2008 Male 9/25/2008 Physician Germany
Primary
Secondary
Concomitant
Renal Failure Hospitalization 6/5/2008 Female 9/26/2008 Physician Poland
Primary
Concomitant
Renal Failure Hospitalization 6/5/2008 Female 10/8/2008 Physician Poland
Primary
Concomitant
Urinary Retention Hospitalization 9/1/2008 Male 10/8/2008 Physician Germany
Primary
Secondary
Concomitant
Ileal Ulcer Other Serious 10/1/2008 Male 172 lb 10/10/2008 Other Health Professional Canada
Primary
Secondary
Concomitant
Urinary Retention Hospitalization 9/1/2008 Male 10/20/2008 Physician Germany
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 9/21/2008 Male 172 lb 10/21/2008 Other Health Professional Canada
Primary
Secondary
Concomitant
Sepsis Other Serious 9/21/2008 Male 172 lb 12/11/2008 Other Health Professional Canada
Primary
Secondary
Concomitant
Intestinal Perforation Hospitalization 12/1/2008 Male 12/16/2008 Physician Hong Kong
Primary
Secondary
Concomitant
Hyponatraemia Hospitalization 10/21/2008 Male 158 lb 12/17/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Diarrhoea Hospitalization 2/14/2008 Male 220 lb 1/14/2009 Physician Switzerland
Primary
Concomitant
Hyponatraemia Hospitalization 10/21/2008 Male 158 lb 1/16/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Pneumonia Aspiration Hospitalization 12/1/2008 Male 1/26/2009 Physician Hong Kong
Primary
Secondary
Concomitant
Hyponatraemia Hospitalization 10/21/2008 Male 158 lb 2/4/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Pneumonia Aspiration Hospitalization 12/2/2008 Male 2/5/2009 Physician France
Primary
Secondary
Concomitant
Pneumonia Aspiration Life Threatening 12/1/2008 Male 157 lb 2/13/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Pneumonia Aspiration Life Threatening 12/1/2008 Male 2/18/2009 Other Health Professional Hong Kong
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 12/2/2008 75 Male 2/11/2009 Physician Hong Kong
Primary
Secondary
Concomitant
Weight Decreased Death 2/16/2009 Male 209 lb 3/2/2009 Physician France
Primary
Secondary
Concomitant
Diarrhoea Hospitalization 2/16/2009 Male 209 lb 3/17/2009 Physician Japan
Primary
Secondary
Concomitant
Pneumonia Aspiration Life Threatening 12/1/2008 Male 3/26/2009 Other Health Professional Hong Kong
Primary
Secondary
Concomitant
Hyponatraemia Hospitalization 10/21/2008 Male 158 lb 3/27/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Hospitalisation Hospitalization 2/7/2007 3/31/2009 Physician Germany
Primary
Secondary
Concomitant
General Physical Health Deterioration Hospitalization 12/27/2008 Male 4/13/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Hepatitis Chronic Active Hospitalization 2/7/2007 7/3/2009 Physician Germany
Primary
Secondary
Concomitant
Pneumonia Hospitalization 2/9/2009 Male 8/10/2009 Physician Germany
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 7/27/2009 68 10/12/2009 Physician Japan
Primary
Secondary
Concomitant
Lung Infection Hospitalization 7/27/2009 68 10/28/2009 Physician Japan
Primary
Secondary
Concomitant
Pneumonia Aspiration Hospitalization 12/2/2008 Male 11/20/2009 Physician France
Primary
Secondary
Concomitant
Hepatitis Chronic Active Hospitalization 2/7/2007 12/1/2009 Physician Germany
Primary
Secondary
Concomitant
Convulsion Hospitalization 10/18/2009 Male 12/23/2009 Physician United States
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Hospitalization 10/18/2009 58 Male 1/4/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Lung Infection Hospitalization 7/27/2009 68 Male 132 lb 2/5/2010 Physician Japan
Primary
Secondary
Concomitant
Myocardial Infarction Hospitalization 2/10/2010 70 Male 2/16/2010 Physician Germany
Primary
Secondary
Concomitant
Acute Myocardial Infarction Hospitalization 2/10/2010 70 Male 3/9/2010 Physician Germany
Primary
Secondary
Concomitant
Dyspnoea Other Serious 11/27/2007 62 Female 3/25/2010 Other Health Professional United States
Primary
Concomitant
Lung Infection Hospitalization 7/27/2009 68 Male 132 lb 4/9/2010 Physician Japan
Primary
Secondary
Concomitant
Respiratory Failure Death 7/1/2008 87 Male 5/4/2010 Physician Belgium
Primary
Secondary
Concomitant
Diarrhoea Other Serious 3/9/2010 68 Female 130 lb 5/11/2010 Physician United States
Primary
Secondary
Concomitant
Pneumonia Aspiration Hospitalization 12/2/2008 75 Male 5/12/2010 Physician France
Primary
Secondary
Concomitant
Diarrhoea Death 4/2/2010 75 Male 6/10/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Diarrhoea Other Serious 3/9/2010 68 Female 130 lb 6/17/2010 Physician United States
Primary
Secondary
Concomitant
Diarrhoea Other Serious 3/9/2010 68 Female 130 lb 7/8/2010 Physician United States
Primary
Secondary
Concomitant
Wound Dehiscence Hospitalization 6/22/2010 64 Male 7/13/2010 Physician Belgium
Primary
Secondary
Concomitant
Fistula Hospitalization 6/22/2010 64 Male 8/4/2010 Physician Belgium
Primary
Secondary
Concomitant
Weight Decreased Other Serious 71 Male 265 lb 9/17/2010 Consumer United States
Primary
Concomitant
Pneumonia Hospitalization 2/9/2009 73 Male 9/24/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Ischaemic Stroke Hospitalization 1/27/2010 74 Male 12/6/2010 Physician France
Primary
Secondary
Concomitant
Malignant Neoplasm Progression Hospitalization 1/27/2010 74 Male 11/29/2010 Other Health Professional France
Primary
Secondary
Concomitant
Cholecystectomy Hospitalization 12/9/2009 37 Male 1/27/2011 Physician United States
Primary
Secondary
Concomitant
Wound Dehiscence Other Serious 6/22/2010 64 Male 2/15/2011 Physician Belgium
Primary
Secondary
Concomitant
Cardiac Failure Acute Life Threatening 5/15/2011 16 Male 6/16/2011 Physician Italy
Primary
Concomitant
Colitis Other Serious 7/25/2011 67 Male 182 lb 8/5/2011 Physician United States
Primary
Concomitant
Failure To Thrive Other Serious 7/25/2011 67 Male 182 lb 8/8/2011 Physician United States
Primary
Concomitant
Leukopenia Other Serious 8/23/2011 72 Male 143 lb 8/26/2011 Physician Germany
Primary
Concomitant
Dyspnoea Other Serious 7/25/2011 67 Male 182 lb 8/28/2011 Physician United States
Primary
Concomitant
Colitis Other Serious 7/25/2011 67 Male 182 lb 8/30/2011 Physician United States
Primary
Concomitant
Failure To Thrive Other Serious 7/25/2011 67 Male 182 lb 9/2/2011 Physician United States
Primary
Concomitant
Leukopenia Other Serious 8/23/2011 72 Male 143 lb 9/6/2011 Physician Germany
Primary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 7/4/2011 49 Male 9/19/2011 Other Health Professional Italy
Primary
Secondary
Concomitant
Acquired Epidermolysis Bullosa Hospitalization 7/4/2011 50 Male 9/14/2011 Other Health Professional Italy
Primary
Secondary
Concomitant
Off Label Use Other Serious 7/4/2011 50 Male 9/20/2011 Physician Italy
Primary
Concomitant
Leukopenia Hospitalization 8/23/2011 72 Male 143 lb 9/21/2011 Physician Germany
Primary
Concomitant
Hyperammonaemia Hospitalization 8/19/2011 67 Male 137 lb 9/29/2011 Physician Japan
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 8/23/2011 72 Male 143 lb 10/5/2011 Physician Germany
Primary
Concomitant
Pulmonary Embolism Hospitalization 8/23/2011 72 Male 143 lb 10/12/2011 Physician Germany
Primary
Concomitant
Renal Cancer Hospitalization 58 Male 146 lb 10/14/2011 Physician Germany
Primary
Secondary
Concomitant
Cholinergic Syndrome Hospitalization 9/22/2011 62 Male 157 lb 10/14/2011 Physician Japan
Primary
Secondary
Concomitant
Renal Failure Hospitalization 8/23/2011 72 Male 143 lb 10/17/2011 Physician Germany
Primary
Concomitant
Leukopenia Hospitalization 8/23/2011 72 Male 143 lb 10/24/2011 Physician Germany
Primary
Concomitant
Renal Failure Hospitalization 8/23/2011 72 Male 143 lb 10/28/2011 Physician Germany
Primary
Concomitant
Gastric Ulcer Hospitalization 9/22/2011 62 Male 157 lb 11/3/2011 Physician Japan
Primary
Secondary
Concomitant
Renal Cell Carcinoma Hospitalization 8/16/2011 58 Male 146 lb 11/30/2011 Physician Germany
Primary
Secondary
Concomitant
Death Hospitalization 12/14/2011 68 Male 122 lb 1/4/2012 Physician United States
Primary
Secondary
Concomitant
Febrile Neutropenia Death 12/1/2011 68 Male 122 lb 1/19/2012 Physician United States
Primary
Secondary
Concomitant
Pyrexia Death 2/13/2011 47 Female 108 lb 2/3/2012 Physician Greece
Primary
Concomitant
Disease Progression Other Serious 11/23/2011 Male 207 lb 2/15/2012 Germany
Primary
Secondary
Concomitant
Septic Embolus Death 11/23/2011 Male 207 lb 3/15/2012 Physician Germany
Primary
Secondary
Concomitant
Hypertension Hospitalization 3/3/2012 73 Male 121 lb 3/23/2012 Consumer Japan
Primary
Secondary
Concomitant
Colitis Ischaemic Death Male 3/23/2012 Physician France
Primary
Secondary
Concomitant
Hypertension Hospitalization 3/3/2012 73 Male 121 lb 4/3/2012 Other Health Professional Japan
Primary
Secondary
Concomitant
Neutrophil Count Decreased Other Serious 3/26/2011 67 Male 108 lb 4/5/2012 Consumer Japan
Primary
Secondary
Concomitant
Depression Life Threatening 7/19/2008 58 Male 4/12/2012 Physician United States
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 7/4/2011 50 Male 6/11/2012 Italy
Primary
Secondary
Concomitant
Biliary Colic Hospitalization 7/8/2011 48 Male 243 lb 6/11/2012 Germany
Primary
Secondary
Concomitant
Depression Life Threatening 7/19/2008 58 Male 6/21/2012 United States
Primary
Secondary
Concomitant
Transient Ischaemic Attack Hospitalization 4/23/2012 75 Male 7/19/2012 Consumer Belgium
Primary
Secondary
Concomitant
Cerebral Haemorrhage Hospitalization 1/27/2010 74 Male 8/2/2012 Other Health Professional France
Primary
Secondary
Concomitant
Blood Creatinine Increased Other Serious 3/9/2010 68 Female 130 lb 8/20/2012 Physician Portugal
Primary
Secondary
Concomitant
Splenic Rupture Other Serious 4/2011 65 Male 12/3/2012 Physician De
Primary
Secondary
Concomitant
Extrasystoles Other Serious 9/5/2012 Male 9/28/2012 Physician De
Primary
Secondary
Concomitant
Posterior Reversible Encephalopathy Syndrome Death 8/9/2012 81 Male 10/5/2012 Physician Fr
Primary
Secondary
Concomitant
Vomiting Hospitalization 9/21/2012 73 Male 181 lb 10/31/2012 Physician De
Primary
Secondary
Concomitant
Vomiting Hospitalization 9/21/2012 72 Male 181 lb 11/9/2012 Physician De
Primary
Secondary
Concomitant
Vomiting Hospitalization 9/21/2012 72 Male 181 lb 11/8/2012 Physician De
Primary
Secondary
Concomitant
Skin Fissures Other Serious 7/2012 77 Male 192 lb 3/31/2013 Consumer De
Primary
Concomitant
Diarrhoea Death 9/19/2012 75 Female 130 lb 2/28/2013 Physician Fr
Primary
Secondary
Concomitant

Drug Data