Allopurinol combined with Nifedipine

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Angioneurotic Oedema Life Threatening 9/7/2005 55 Male 1/5/2006 Other Health Professional United States
Primary
Concomitant
Renal Cyst Other Serious 12/21/2005 56 Male 1/4/2006 Japan
Primary
Concomitant
Ventricular Hypertrophy Other Serious 1/5/2006 83 Female 190 lb 1/30/2006 Other Health Professional Canada
Primary
Concomitant
Gastric Ulcer Haemorrhage Hospitalization 11/9/2005 74 Male 1/25/2006 Japan
Primary
Concomitant
Thrombophlebitis Hospitalization 5/14/2005 33 Male 2/7/2006 Physician United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 9/22/2005 64 Male 2/8/2006 Physician Japan
Primary
Concomitant
Seroma Hospitalization 1/24/2006 43 Female 2/7/2006 Other Health Professional Hungary
Primary
Concomitant
Thrombophlebitis Hospitalization 5/14/2005 33 Male 2/10/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Intestinal Haemorrhage Hospitalization 1/8/2004 63 Female 157 lb 2/14/2006 Lawyer United States
Primary
Concomitant
Urine Leukocyte Esterase Positive Hospitalization 1/10/2006 63 Male 2/9/2006 United States
Primary
Secondary
Concomitant
Pseudoaldosteronism Hospitalization 1/1/2005 63 Male 150 lb 2/17/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 1/10/2006 63 Male 2/24/2006 United States
Primary
Secondary
Concomitant
Urine Output Decreased Other Serious 10/22/2004 45 Male 216 lb 2/28/2006 Physician Japan
Primary
Concomitant
Suicide Attempt Life Threatening 12/4/2004 51 Male 3/6/2006 Physician Japan
Primary
Secondary
Seroma Other Serious 1/24/2006 43 Female 3/6/2006 Hungary
Primary
Concomitant
Weight Decreased 1/1/2005 74 Male 170 lb 12/28/2005 United States
Primary
Concomitant
Unresponsive To Verbal Stimuli Hospitalization 11/27/2003 62 Male 3/20/2006 Physician United States
Primary
Concomitant
Odynophagia Hospitalization 1/15/2006 71 Male 3/10/2006 Physician Japan
Primary
Secondary
Myocardial Infarction Other Serious 1/1/2002 72 Female 251 lb 3/22/2006 Lawyer United States
Primary
Concomitant
Renal Failure Acute Life Threatening 6/9/2005 Male 170 lb 3/22/2006 United States
Primary
Concomitant
Angioneurotic Oedema Hospitalization 1/15/2006 71 Male 3/17/2006 Physician Japan
Primary
Secondary
Skin Exfoliation Other Serious 11/1/2005 64 Male 177 lb 3/20/2006 Physician United States
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 1/15/2006 71 Male 4/3/2006 Physician Japan
Primary
Secondary
Vertebral Artery Occlusion Hospitalization 11/27/2003 62 Male 201 lb 4/11/2006 Physician United States
Primary
Concomitant
Insomnia 1/4/2006 82 Male 270 lb 2/2/2006 Consumer United States
Primary
Secondary
Concomitant
Therapy Non-responder Life Threatening 12/4/2004 51 Male 4/3/2006 Other Health Professional Japan
Primary
Secondary
Shunt Occlusion Other Serious 12/21/2005 56 Male 4/10/2006 Physician Japan
Primary
Concomitant
Liver Disorder Hospitalization 12/28/2005 Male 4/24/2006 Physician France
Primary
Concomitant
Ventricular Hypertrophy Other Serious 1/5/2006 83 Female 190 lb 5/10/2006 Other Health Professional Canada
Primary
Concomitant
Chorioretinopathy Other Serious 36 Male 5/12/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Pulmonary Congestion Other Serious 5/27/2003 69 Male 161 lb 5/12/2006 Lawyer United States
Primary
Concomitant
Pneumonia Life Threatening 6/9/2005 Male 170 lb 5/12/2006 United States
Primary
Concomitant
Oedema Peripheral Life Threatening 3/8/2006 81 Female 5/9/2006 Physician Germany
Primary
Concomitant
Weight Decreased 1/1/2005 74 Male 170 lb 4/25/2006 Physician United States
Primary
Concomitant
Productive Cough Other Serious 70 Male 7/3/2006 Consumer United States
Primary
Concomitant
Blood Glucose Increased 41 Male 7/21/2006 Consumer United States
Primary
Concomitant
Loss Of Consciousness Hospitalization 6/15/2006 88 Male 198 lb 7/6/2006 Pharmacist United States
Primary
Concomitant
White Blood Cell Count Decreased Life Threatening 12/28/2005 58 Male 7/20/2006 Japan
Primary
Concomitant
Urinary Hesitation Hospitalization 7/29/2006 72 Male 219 lb 8/2/2006 Pharmacist United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 4/5/2006 89 Male 97 lb 7/31/2006 Physician Japan
Primary
Concomitant
Retroperitoneal Haemorrhage Other Serious 9/17/2004 74 Female 141 lb 8/28/2006 Australia
Primary
Secondary
Concomitant
Speech Disorder Hospitalization 8/20/2006 56 Male 141 lb 9/5/2006 Physician Japan
Primary
Concomitant
Renal Impairment Hospitalization 5/9/2006 83 Male 9/20/2006 Japan
Primary
Secondary
Concomitant
Haemoglobin Decreased Life Threatening 3/24/2005 49 Male 196 lb 9/27/2006 Pharmacist United States
Primary
Concomitant
Coronary Artery Dissection Other Serious 9/12/2006 Male 256 lb 10/5/2006 Physician Belgium
Primary
Concomitant
Skin Necrosis Hospitalization 8/18/2006 63 Male 10/12/2006 Consumer France
Primary
Concomitant
Bladder Cancer Other Serious 11/1/2006 Female 182 lb 11/20/2006 Physician United States
Primary
Concomitant
Venoocclusive Disease Other Serious 10/14/2006 11 Female 60 lb 11/30/2006 Physician Canada
Primary
Concomitant
Ureteral Neoplasm Other Serious 11/1/2006 Female 182 lb 12/18/2006 Physician United States
Primary
Concomitant
Therapeutic Response Decreased Male 12/22/2006 Pharmacist United States
Primary
Concomitant
Pyrexia 1/1/2005 Male 12/22/2006 Other Health Professional United States
Primary
Concomitant
Duodenal Ulcer Hospitalization 1/24/2007 Male 185 lb 3/7/2007 Germany
Primary
Concomitant
Facial Pain Other Serious 2/1/2006 69 Male 207 lb 3/9/2007 United States
Primary
Secondary
Concomitant
Shock Life Threatening 2/8/2007 3/5/2007 Japan
Primary
Concomitant
Glycosylated Haemoglobin Increased Disability 10/1/2006 64 Male 3/7/2007 United Kingdom
Primary
Concomitant
Ureteral Neoplasm Other Serious 11/1/2006 Female 182 lb 3/15/2007 Physician United States
Primary
Concomitant
Performance Status Decreased Other Serious 10/24/2006 Male 3/21/2007 Physician Austria
Primary
Secondary
Concomitant
Resuscitation Other Serious 10/24/2006 Male 3/29/2007 Physician Austria
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 11/2/2006 58 Male 268 lb 3/29/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Gynaecomastia Other Serious 57 Male 11/22/2006 Germany
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 11/2/2006 58 Male 268 lb 4/4/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Resuscitation Other Serious 10/24/2006 Male 4/6/2007 Physician Austria
Primary
Secondary
Concomitant
International Normalised Ratio Increased Hospitalization 3/20/2007 52 Male 4/9/2007 Denmark
Primary
Concomitant
Hallucination Hospitalization 3/1/2007 38 Female 92 lb 4/6/2007 Pharmacist Japan
Primary
Concomitant
Teratoma Other Serious 1/1/2005 40 Male 4/21/2007 Pharmacist Ireland
Primary
Secondary
Concomitant
Ventricular Hypertrophy Other Serious 1/5/2007 65 Male 4/20/2007 Japan
Primary
Concomitant
Weight Decreased Other Serious 1/1/2006 Male 190 lb 5/3/2007 Consumer United States
Primary
Concomitant
Viral Infection Hospitalization 11/2/2006 58 Male 268 lb 5/10/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Hypocalcaemia Hospitalization 71 Male 5/11/2007 Physician United States
Primary
Concomitant
Supraventricular Extrasystoles Other Serious 1/5/2007 65 Male 5/21/2007 Japan
Primary
Concomitant
Glycosylated Haemoglobin Increased Disability 10/1/2006 64 Male 5/31/2007 United Kingdom
Primary
Concomitant
Hiccups 12/19/2006 85 Male 180 lb 6/25/2007 United States
Primary
Concomitant
Blood Urea Increased Life Threatening 12/22/2006 Male 7/6/2007 United Kingdom
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 9 Male 7/10/2007 Other Health Professional Sweden
Primary
Concomitant
Shock Life Threatening 2/8/2007 73 Female 101 lb 7/3/2007 Japan
Primary
Concomitant
Weight Decreased Other Serious 80 Male 7/16/2007 Physician Switzerland
Primary
Concomitant
Weight Decreased Other Serious 1/1/2006 Male 190 lb 7/18/2007 Physician United States
Primary
Concomitant
Resuscitation Other Serious 10/24/2006 Male 7/23/2007 Physician Austria
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 9 Male 8/3/2007 Other Health Professional Sweden
Primary
Concomitant
Pyrexia Hospitalization 1/1/2005 Male 8/3/2007 Physician Austria
Primary
Concomitant
Weight Increased Other Serious 1/1/2006 Male 198 lb 8/7/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Teratoma Other Serious 1/1/2005 40 Male 9/11/2007 Pharmacist Ireland
Primary
Secondary
Concomitant
Pancytopenia Hospitalization 9/12/2007 Male 9/17/2007 Pharmacist United States
Primary
Concomitant
Toxic Epidermal Necrolysis Required Intervention 10 Male 9/17/2007 Other Health Professional Sweden
Primary
Secondary
Concomitant
Pyrexia Hospitalization 1/1/2005 Male 9/28/2007 Physician Austria
Primary
Concomitant
Skin Turgor Decreased Hospitalization 2/11/2007 82 Female 9/26/2007 Other Health Professional United States
Primary
Concomitant
Rhabdomyolysis Other Serious 73 Male 132 lb 10/1/2007 Other Health Professional United Kingdom
Primary
Concomitant
Pyrexia Hospitalization 1/1/2005 Male 10/5/2007 Physician Austria
Primary
Concomitant
Volume Blood Decreased Disability 8/8/2007 Female 137 lb 10/30/2007 Physician Japan
Primary
Secondary
Concomitant
Pleural Effusion Hospitalization 10/23/2007 Male 154 lb 11/5/2007 Germany
Primary
Concomitant
Renal Impairment Hospitalization 7/26/2002 Male 139 lb 11/6/2007 Hong Kong
Primary
Secondary
Concomitant
Resuscitation Other Serious 10/24/2006 Male 11/7/2007 Physician Austria
Primary
Secondary
Concomitant
Pyrexia Hospitalization 8/20/2006 56 Male 141 lb 11/2/2007 Physician Japan
Primary
Concomitant
Speech Disorder Hospitalization 8/20/2006 56 Male 141 lb 11/14/2007 Physician Japan
Primary
Concomitant
Venoocclusive Liver Disease Other Serious 10/14/2006 11 Female 60 lb 11/8/2007 Physician Canada
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 10 Male 11/8/2007 Sweden
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 9 Male 11/21/2007 Sweden
Primary
Secondary
Concomitant
Pleural Effusion Hospitalization 10/23/2007 Male 154 lb 11/26/2007 Germany
Primary
Concomitant
Hypocalcaemia Other Serious 9/24/2007 Female 12/3/2007 Other Health Professional United States
Primary
Concomitant
Skin Turgor Decreased Hospitalization 2/11/2007 82 Female 11/28/2007 Other Health Professional United States
Primary
Concomitant
Pleural Effusion Hospitalization 10/23/2007 Male 154 lb 12/5/2007 Germany
Primary
Concomitant
Toxic Epidermal Necrolysis Other Serious 10 Male 12/14/2007 Sweden
Primary
Secondary
Concomitant
Blood Calcium Increased 9/1/2007 64 Female 226 lb 12/17/2007 Other Health Professional United States
Primary
Concomitant
Overdose Hospitalization 1/7/2003 83 Male 143 lb 12/21/2007 France
Primary
Concomitant
Interacting
Infection Hospitalization 12/11/2007 79 Male 168 lb 12/31/2007 Physician Finland
Primary
Secondary
Concomitant
Hallucination Other Serious 8/27/2007 Male 252 lb 1/18/2008
Primary
Concomitant
Stevens-johnson Syndrome Death 4/19/2005 80 Female 1/22/2008 Physician Germany
Primary
Secondary
Concomitant
Stevens-johnson Syndrome Death 4/19/2005 Female 1/25/2008 Physician Germany
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 5/25/2006 74 Female 1/22/2008 Australia
Primary
Secondary
Coronary Artery Occlusion Hospitalization 6/28/2007 80 Male 12/3/2007 Consumer United States
Primary
Concomitant
Respiratory Failure Hospitalization 11/14/2006 58 Male 269 lb 2/18/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Blood Glucose Increased 81 Female 154 lb 2/25/2008 Consumer United States
Primary
Concomitant
Vomiting Other Serious 3/10/2007 74 Male 101 lb 2/22/2008 Physician Japan
Primary
Concomitant
Dysarthria Hospitalization 2/1/2008 83 Female 176 lb 2/26/2008 Consumer Netherlands
Primary
Concomitant
Performance Status Decreased Other Serious 10/24/2006 Male 3/6/2008 Physician Austria
Primary
Secondary
Concomitant
Infection Hospitalization 12/11/2007 79 Male 168 lb 3/7/2008 Physician Finland
Primary
Secondary
Concomitant
Vomiting Other Serious 3/10/2007 74 Male 101 lb 3/4/2008 Physician Japan
Primary
Concomitant
Visual Disturbance Other Serious 11/1/2007 79 Male 3/27/2008 Consumer United States
Primary
Concomitant
Renal Failure Other Serious 3/10/2007 74 Male 101 lb 4/10/2008 Physician Japan
Primary
Concomitant
Weight Decreased Hospitalization 2/14/2008 Male 220 lb 4/25/2008 Physician Switzerland
Primary
Concomitant
Weight Increased Hospitalization 1/2/2008 69 Male 4/29/2008 Japan
Primary
Concomitant
Drug Interaction Other Serious 4/1/2007 47 Male 5/12/2008 Other Health Professional Italy
Primary
Secondary
Concomitant
Interacting
Erythropoiesis Abnormal Other Serious 47 Male 5/8/2008 Italy
Primary
Secondary
Concomitant
Renal Failure Other Serious 1/1/2007 45 Male 5/19/2008 Consumer United States
Primary
Concomitant
Nephritis Hospitalization 12/22/2006 Male 5/27/2008 United Kingdom
Primary
Concomitant
Renal Failure Other Serious 1/1/2007 45 Male 6/3/2008 Physician United States
Primary
Concomitant
Drug Rash With Eosinophilia And Systemic Symptoms Hospitalization 6/1/2006 44 Male 6/16/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Vision Blurred Life Threatening 69 Male 7/16/2008 United States
Primary
Concomitant
Somnolence 4/1/2007 66 Female 7/24/2008 Consumer United States
Primary
Concomitant
Fatigue Hospitalization 2/14/2008 Male 220 lb 7/29/2008 Physician Switzerland
Primary
Concomitant
Psoriasis Other Serious 8/14/2007 Female 8/1/2008 Other Health Professional Germany
Primary
Concomitant
Renal Impairment Other Serious 6/16/2008 83 Female 8/5/2008 Physician Japan
Primary
Concomitant
Lymphadenopathy Other Serious 8/14/2007 Female 8/6/2008 Other Health Professional Germany
Primary
Concomitant
Renal Failure Other Serious 1/1/2007 45 Male 7/31/2008 Physician United States
Primary
Concomitant
Respiratory Failure Hospitalization 5/1/2008 53 Female 8/8/2008 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 4/1/2008 Female 8/12/2008 Physician United States
Primary
Concomitant
Interacting
Vision Blurred Life Threatening 6/14/2008 72 Male 130 lb 8/12/2008 United States
Primary
Concomitant
Renal Failure Hospitalization 6/5/2008 Female 8/18/2008 Physician Poland
Primary
Concomitant
Hyperkalaemia Hospitalization 11/30/2007 Male 198 lb 8/21/2008 Physician Germany
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 11/14/2006 58 Male 269 lb 9/2/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Failure Hospitalization 6/5/2008 Female 9/5/2008 Physician Poland
Primary
Concomitant
Renal Failure Hospitalization 6/5/2008 Female 9/16/2008 Physician Poland
Primary
Concomitant
Nephrogenic Systemic Fibrosis Other Serious 3/24/2003 9/24/2008 Physician United States
Primary
Secondary
Concomitant
Renal Failure Hospitalization 6/5/2008 Female 9/26/2008 Physician Poland
Primary
Concomitant
Lymphadenopathy Other Serious 8/14/2007 Female 9/26/2008 Other Health Professional Germany
Primary
Concomitant
Tubulointerstitial Nephritis Hospitalization 12/22/2006 Male 9/29/2008 United Kingdom
Primary
Concomitant
Urinary Retention Hospitalization 9/21/2006 81 Male 121 lb 9/30/2008 Other Health Professional Japan
Primary
Concomitant
Renal Failure Hospitalization 6/5/2008 Female 10/8/2008 Physician Poland
Primary
Concomitant
Myelodysplastic Syndrome Other Serious 9/6/2008 Male 10/17/2008 Other Health Professional United States
Primary
Concomitant
Syringomyelia Other Serious 1/1/2008 61 Male 188 lb 10/20/2008 Other Health Professional United States
Primary
Concomitant

Drug Data