Allopurinol combined with Nexavar

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Skin Chapped Other Serious 1/29/2006 52 Male 2/22/2006 United States
Primary
Concomitant
Rash Other Serious 1/29/2006 52 Male 4/10/2006 United States
Primary
Concomitant
Rash Other Serious 1/29/2006 52 Male 4/10/2006 United States
Primary
Concomitant
Yellow Skin Male 4/24/2006 United States
Primary
Concomitant
Stomatitis Other Serious 2/1/2006 68 Male 195 lb 4/24/2006 United States
Primary
Concomitant
Skin Exfoliation Other Serious 1/29/2006 52 Male 6/21/2006 United States
Primary
Concomitant
Syncope Other Serious 2/1/2006 80 Male 145 lb 7/3/2006 United States
Primary
Concomitant
Syncope Other Serious 2/1/2006 80 Male 145 lb 7/19/2006 United States
Primary
Concomitant
Stomatitis 1/1/2006 58 Male 142 lb 7/12/2006 United States
Primary
Concomitant
Hypertension 5/18/2006 70 Male 7/12/2006 United States
Primary
Concomitant
Tongue Discolouration 1/1/2006 78 Male 7/12/2006 United States
Primary
Concomitant
Nausea Disability 2/14/2006 59 Male 7/12/2006 Physician United States
Primary
Concomitant
Stomatitis Other Serious 2/1/2006 68 Male 197 lb 7/12/2006 United States
Primary
Concomitant
Yellow Skin Male 200 lb 7/12/2006 Other Health Professional United States
Primary
Concomitant
Prostate Cancer Metastatic Death 7/27/2006 74 Male 9/7/2006 Consumer United States
Primary
Concomitant
Vomiting Other Serious 1/1/2006 91 Male 10/3/2006 United States
Primary
Concomitant
Rash Other Serious 1/1/2006 76 Male 11/21/2006 United States
Primary
Concomitant
Stomatitis 1/1/2006 58 Male 142 lb 11/6/2006 United States
Primary
Concomitant
Stomatitis Other Serious 2/1/2006 68 Male 197 lb 10/23/2006 United States
Primary
Concomitant
Facial Pain Other Serious 2/1/2006 69 Male 207 lb 3/9/2007 United States
Primary
Secondary
Concomitant
Skin Cancer Other Serious 2/1/2006 77 Female 143 lb 3/14/2007 United States
Primary
Concomitant
Renal Cell Carcinoma Stage Unspecified Other Serious 1/29/2007 64 Male 181 lb 3/22/2007 Other Health Professional United States
Primary
Concomitant
Skin Cancer Other Serious 1/1/2006 78 Female 130 lb 3/28/2007 United States
Primary
Concomitant
Renal Cell Carcinoma Stage Unspecified Other Serious 1/29/2007 64 Male 181 lb 5/7/2007 Other Health Professional United States
Primary
Concomitant
Temperature Regulation Disorder 6/6/2006 65 Male 217 lb 1/23/2007 United States
Primary
Secondary
Concomitant
Pain 11/1/2006 59 Male 1/23/2007 United States
Primary
Concomitant
Pneumoperitoneum Life Threatening 7/6/2007 58 Female 364 lb 7/11/2007 Pharmacist United States
Primary
Concomitant
Weight Decreased Other Serious 12/1/2006 76 Male 7/19/2007 Consumer United States
Primary
Concomitant
Rash Other Serious 1/1/2006 76 Male 8/1/2007 United States
Primary
Concomitant
Rash Other Serious 1/1/2006 76 Male 8/2/2007 United States
Primary
Concomitant
Stomatitis Hospitalization 7/10/2007 76 Male 8/30/2007 United States
Primary
Concomitant
Stomatitis Hospitalization 7/10/2007 76 Male 9/3/2007 United States
Primary
Concomitant
Stomatitis Hospitalization 7/10/2007 76 Male 9/6/2007 United States
Primary
Concomitant
Nausea Other Serious 76 Male 9/6/2007 Other Health Professional Canada
Primary
Concomitant
Testicular Pain 3/25/2007 56 Male 8/1/2007 United States
Primary
Concomitant
Pain In Extremity 6/1/2007 64 Male 10/12/2007 Consumer United States
Primary
Concomitant
Stomatitis Life Threatening 7/6/2007 58 Female 165 lb 10/12/2007 United States
Primary
Concomitant
Nausea Other Serious 4/9/2007 76 Male 223 lb 12/3/2007 Other Health Professional Canada
Primary
Concomitant
Hypocalcaemia Other Serious 9/24/2007 Female 12/3/2007 Other Health Professional United States
Primary
Concomitant
Stomatitis Life Threatening 7/6/2007 58 Female 364 lb 12/18/2007 Pharmacist United States
Primary
Concomitant
Skin Cancer Other Serious 1/1/2006 78 Female 130 lb 1/29/2008 United States
Primary
Concomitant
Nausea Other Serious 4/9/2007 76 Male 223 lb 2/22/2008 Other Health Professional Canada
Primary
Concomitant
Skin Burning Sensation Hospitalization 7/10/2007 76 Male 3/21/2008 United States
Primary
Concomitant
Hepatic Function Abnormal Hospitalization 6/3/2008 77 Male 146 lb 6/20/2008 Physician Japan
Primary
Concomitant
Hepatic Function Abnormal Other Serious 6/12/2008 61 Male 6/20/2008 Physician Japan
Primary
Concomitant
Stomatitis Hospitalization 4/4/2008 65 Male 119 lb 7/24/2008 Physician Japan
Primary
Concomitant
Renal Impairment Hospitalization 6/18/2008 79 Male 112 lb 8/4/2008 Physician Japan
Primary
Concomitant
Hypocalcaemia Other Serious 2/1/2008 80 Female 126 lb 9/11/2008 Pharmacist Germany
Primary
Concomitant
Febrile Neutropenia Hospitalization 8/29/2008 71 Male 9/15/2008 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 8/29/2008 71 Male 9/24/2008 Physician United States
Primary
Secondary
Concomitant
Vitamin D Decreased Other Serious 1/1/2006 71 Male 240 lb 11/10/2008 United States
Primary
Concomitant
Weight Decreased Other Serious 4/1/2008 75 Male 181 lb 11/10/2008 Physician United States
Primary
Concomitant
Renal Failure Acute Other Serious 10/14/2008 74 Female 132 lb 3/13/2009 Physician Denmark
Primary
Secondary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 11/20/2008 61 Male 148 lb 3/16/2009 Physician Japan
Primary
Concomitant
Epistaxis Hospitalization 4/1/2008 79 Male 3/18/2009 Other Health Professional United States
Primary
Concomitant
Mucosal Inflammation Life Threatening 1/12/2009 48 Male 181 lb 5/8/2009 Physician Germany
Primary
Concomitant
Skin Tightness Other Serious 64 Male 7/2/2009 Other Health Professional United States
Primary
Concomitant
Laboratory Test Abnormal Hospitalization 2/16/2009 81 Male 220 lb 7/9/2009 Germany
Primary
Concomitant
Rash Other Serious 11/20/2008 61 Male 148 lb 7/30/2009 Physician Japan
Primary
Secondary
Concomitant
Skin Tightness Death 64 Male 8/7/2009 Other Health Professional United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 5/27/2009 62 Male 9/25/2009 Physician Japan
Primary
Secondary
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 1/9/2009 59 Female 150 lb 9/28/2009 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Hospitalization 8/21/2009 80 Male 123 lb 9/29/2009 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Hospitalization 7/18/2008 64 Male 154 lb 9/29/2009 Physician Japan
Primary
Concomitant
Truncus Coeliacus Thrombosis Hospitalization 7/8/2009 70 Male 106 lb 9/29/2009 Pharmacist Japan
Primary
Concomitant
Troponin T Increased Other Serious Male 10/22/2009 Physician Austria
Primary
Secondary
Concomitant
Liver Function Test Abnormal Disability 9/25/2009 80 Male 198 lb 11/3/2009 Physician Germany
Primary
Concomitant
Liver Function Test Abnormal Disability 9/25/2009 80 Male 198 lb 11/4/2009 Physician Germany
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Other Serious 10/13/2009 66 Male 157 lb 11/13/2009 Physician Japan
Primary
Concomitant
Temperature Regulation Disorder Hospitalization 6/6/2006 66 Male 216 lb 11/16/2009 Physician United States
Primary
Secondary
Concomitant
Pruritus Disability 9/25/2009 80 Male 198 lb 11/18/2009 Physician Germany
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Other Serious 10/13/2009 66 Male 157 lb 12/4/2009 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 5/27/2009 62 Male 12/29/2009 Physician Japan
Primary
Secondary
Concomitant
Prothrombin Time Abnormal Hospitalization 2/1/2008 80 Male 220 lb 1/8/2010 Germany
Primary
Concomitant
Pruritus 12/1/2009 Male 192 lb 2/16/2010 United States
Primary
Concomitant
Stomatitis Other Serious 7/22/2008 73 Female 134 lb 2/22/2010 Physician Japan
Primary
Secondary
Concomitant
Protein Urine Other Serious 4/25/2008 68 Male 110 lb 3/11/2010 Physician Japan
Primary
Secondary
Concomitant
Shock Haemorrhagic Life Threatening 12/12/2009 75 Male 134 lb 3/15/2010 Physician Japan
Primary
Concomitant
Renal Disorder Other Serious 5/12/2008 79 Male 126 lb 3/18/2010 Physician Japan
Primary
Concomitant
Protein Urine Other Serious 4/25/2008 68 Male 110 lb 3/18/2010 Physician Japan
Primary
Secondary
Concomitant
Renal Cell Carcinoma Hospitalization 8/26/2009 50 Male 106 lb 3/22/2010 Physician Japan
Primary
Concomitant
Pyrexia Hospitalization 6/12/2009 75 Male 134 lb 3/29/2010 Physician Japan
Primary
Secondary
Concomitant
Renal Cell Carcinoma Other Serious 5/21/2008 51 Male 146 lb 3/31/2010 Physician Japan
Primary
Concomitant
Renal Cell Carcinoma Other Serious 5/21/2008 51 Male 146 lb 4/6/2010 Physician Japan
Primary
Concomitant
Hepatic Failure Hospitalization 2/15/2010 76 Male 4/7/2010 Physician Japan
Primary
Concomitant
Renal Failure Death 5/28/2008 76 Male 132 lb 4/7/2010 Physician Japan
Primary
Concomitant
Vomiting Other Serious 7/21/2008 54 Male 134 lb 4/8/2010 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 2/8/2009 56 Male 172 lb 4/19/2010 Physician Japan
Primary
Concomitant
Rash Other Serious 7/29/2009 70 Male 123 lb 4/20/2010 Physician Japan
Primary
Concomitant
Hypertension Hospitalization 1/15/2010 79 Male 154 lb 4/20/2010 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Life Threatening 7/28/2009 69 Male 130 lb 4/23/2010 Physician Japan
Primary
Secondary
Concomitant
Rash Other Serious 9/16/2009 76 Male 99 lb 4/26/2010 Physician Japan
Primary
Secondary
Concomitant
Rash Life Threatening 1/14/2009 69 Male 130 lb 4/26/2010 Physician Japan
Primary
Concomitant
Thrombocytopenia Hospitalization 8/21/2009 80 Male 123 lb 4/26/2010 Physician Japan
Primary
Concomitant
Rash Life Threatening 1/14/2009 69 Male 130 lb 4/28/2010 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 6/25/2009 66 Male 119 lb 4/29/2010 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 3/1/2010 75 Male 137 lb 4/30/2010 Physician Japan
Primary
Concomitant
Skin Necrosis Other Serious 11/4/2008 79 Male 139 lb 5/3/2010 Other Health Professional Belgium
Primary
Concomitant
Suicide Attempt Other Serious 4/26/2010 46 Female 5/5/2010 Physician Egypt
Primary
Concomitant
Renal Failure Death 4/24/2010 72 Male 112 lb 6/7/2010 Physician Japan
Primary
Concomitant
Thrombocytopenia Other Serious 4/2/2010 81 Male 6/14/2010 Physician France
Primary
Secondary
Concomitant
Somnolence Other Serious 1/4/2010 71 Male 8/27/2010 Physician United States
Primary
Concomitant
Somnolence Other Serious 1/4/2010 71 Male 9/3/2010 Physician United States
Primary
Concomitant
Hepatic Encephalopathy Hospitalization 7/29/2010 70 Male 176 lb 9/15/2010 Physician Germany
Primary
Concomitant
Hepatic Encephalopathy Hospitalization 7/29/2010 70 Male 176 lb 9/20/2010 Physician Germany
Primary
Concomitant
Somnolence Other Serious 1/4/2010 71 Male 9/20/2010 Physician United States
Primary
Concomitant
Hepatic Encephalopathy Hospitalization 7/29/2010 70 Male 176 lb 9/29/2010 Physician Germany
Primary
Concomitant
Hepatic Encephalopathy Hospitalization 6/29/2010 70 Male 176 lb 10/21/2010 Physician Germany
Primary
Concomitant
Hepatic Encephalopathy Hospitalization 6/29/2010 70 Male 176 lb 12/27/2010 Physician Germany
Primary
Concomitant
Rash Hospitalization 12/16/2010 65 Male 1/6/2011 Physician Japan
Primary
Secondary
Fatigue 8/1/2008 70 Female 1/13/2011 Consumer United States
Primary
Concomitant
Encephalopathy Death 1/4/2010 71 Male 1/14/2011 Physician United States
Primary
Concomitant
Electrolyte Imbalance Hospitalization 8/1/2008 70 Female 2/4/2011 Pharmacist United States
Primary
Concomitant
Hospitalisation Death 8/23/2010 71 Male 2/5/2011 Physician United States
Primary
Concomitant
Rash Other Serious 12/14/2010 64 Male 110 lb 2/9/2011 Physician Japan
Primary
Secondary
Concomitant
Hepatic Function Abnormal Other Serious 11/20/2008 60 Male 148 lb 3/9/2011 Physician Japan
Primary
Secondary
Concomitant
Rash Hospitalization 12/14/2010 64 Male 110 lb 3/23/2011 Physician Japan
Primary
Secondary
Concomitant
Diarrhoea Hospitalization 8/1/2008 70 Female 3/28/2011 Consumer United States
Primary
Concomitant
Renal Failure Hospitalization 9/1/2010 77 Male 3/31/2011 Consumer United States
Primary
Secondary
Concomitant
Anosmia Hospitalization 6/29/2010 70 Male 176 lb 4/7/2011 Physician Germany
Primary
Concomitant
Hepatic Encephalopathy Other Serious 1/20/2011 78 Female 126 lb 4/27/2011 Physician Japan
Primary
Concomitant
Aspartate Aminotransferase Increased Hospitalization 1/25/2011 82 Male 130 lb 4/29/2011 Physician Japan
Primary
Concomitant
Diarrhoea Other Serious 5/15/2008 60 Male 150 lb 5/16/2011 Physician Japan
Primary
Concomitant
Haemorrhagic Diathesis Other Serious 11/11/2010 77 Female 108 lb 5/16/2011 Physician Japan
Primary
Concomitant
Hepatic Failure Hospitalization 12/31/2010 63 Male 148 lb 5/19/2011 Physician Japan
Primary
Concomitant
General Physical Health Deterioration Hospitalization 11/21/2009 62 Male 5/25/2011 Physician France
Primary
Concomitant
Stomatitis Hospitalization 4/4/2008 65 Male 119 lb 6/3/2011 Physician Japan
Primary
Concomitant
Lipase Increased Life Threatening 1/14/2009 69 Male 130 lb 6/3/2011 Other Health Professional Japan
Primary
Concomitant
Pyrexia Other Serious 8/30/2008 60 Male 152 lb 6/7/2011 Physician Japan
Primary
Secondary
Concomitant
Upper Gastrointestinal Haemorrhage Hospitalization 2/1/2011 79 Female 6/10/2011 Physician Japan
Primary
Concomitant
Hepatic Failure Life Threatening 12/31/2010 63 Male 148 lb 6/14/2011 Physician Japan
Primary
Concomitant
Renal Disorder Other Serious 12/31/2010 63 Male 148 lb 6/28/2011 Pharmacist Japan
Primary
Secondary
Concomitant
Sepsis Other Serious 12/31/2010 63 Male 148 lb 7/5/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Hypophosphataemia Hospitalization 2/1/2011 79 Female 7/11/2011 Physician Japan
Primary
Concomitant
Cough Hospitalization 7/21/2008 54 Male 134 lb 7/15/2011 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Hospitalization 8/1/2008 73 Female 7/20/2011 Physician United States
Primary
Concomitant
Atrial Fibrillation Other Serious 1/4/2010 71 Male 8/5/2011 Consumer United States
Primary
Secondary
Concomitant
Hepatorenal Syndrome Hospitalization 7/23/2009 68 Male 140 lb 8/5/2011 Physician Japan
Primary
Concomitant
Hypophosphataemia Other Serious 7/21/2008 54 Male 134 lb 8/12/2011 Physician Japan
Primary
Concomitant
Hepatic Neoplasm Malignant Other Serious 2/1/2011 79 Female 8/17/2011 Physician Japan
Primary
Concomitant
Pain Death 64 Male 160 lb 8/17/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Hypertension Disability Male 177 lb 8/25/2011 Lawyer United States
Primary
Concomitant
Hypertension Death 6/25/2009 65 Male 119 lb 8/29/2011 Physician Japan
Primary
Concomitant
Decreased Appetite Death 5/20/2010 73 Male 137 lb 9/23/2011 Physician Japan
Primary
Concomitant
Vomiting Male 9/23/2011 Pharmacist United States
Primary
Concomitant
Quality Of Life Decreased Disability Male 177 lb 10/6/2011 Physician United States
Primary
Concomitant
Somnolence Life Threatening 1/4/2010 71 Male 10/20/2011 Physician United States
Primary
Secondary
Concomitant
Hepatic Function Abnormal Life Threatening 7/23/2009 68 Male 141 lb 10/21/2011 Physician Japan
Primary
Concomitant
Interstitial Lung Disease Life Threatening 5/17/2011 45 Male 115 lb 10/24/2011 Physician Japan
Primary
Secondary
Hepatic Encephalopathy Life Threatening 9/16/2011 76 Male 128 lb 10/26/2011 Physician Japan
Primary
Concomitant

Drug Data