Allopurinol combined with Metronidazole

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Rectal Haemorrhage Hospitalization 75 Male 1/10/2006 Physician France
Primary
Secondary
Concomitant
Venoocclusive Disease Life Threatening 11/23/2005 63 Female 121 lb 1/12/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rash Hospitalization 9/12/2005 73 Male 1/31/2006 Pharmacist United States
Primary
Concomitant
Restlessness Hospitalization 1/10/2006 78 Male 198 lb 2/8/2006
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 1/9/2006 75 Female 140 lb 2/3/2006 Other Health Professional United Kingdom
Primary
Concomitant
Restlessness Hospitalization 1/10/2006 78 Male 2/10/2006 United Kingdom
Primary
Concomitant
Septic Shock Hospitalization 10/30/2005 51 Male 3/2/2006 Pharmacist New Zealand
Primary
Concomitant
Obstruction Hospitalization 74 Male 3/16/2006 Pharmacist United States
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 1/9/2006 75 Female 140 lb 3/23/2006 Other Health Professional United Kingdom
Primary
Concomitant
Toxic Skin Eruption Other Serious 1/7/2006 64 Male 181 lb 4/18/2006 Physician France
Primary
Concomitant
Septic Shock Death 4/24/2006 57 Male 245 lb 6/29/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 8/12/2005 54 Male 187 lb 7/14/2006 Other Health Professional Belgium
Primary
Concomitant
Blood Pressure Decreased Death 6/14/2006 Female 249 lb 8/21/2006 Pharmacist United States
Primary
Concomitant
Treatment Noncompliance Required Intervention 5/3/2006 67 Female 8/16/2006 Physician United States
Primary
Concomitant
Vascular Calcification Life Threatening 10/15/2005 67 Male 183 lb 9/8/2006 United States
Primary
Concomitant
Pulmonary Oedema Life Threatening 12/7/2004 68 Female 199 lb 9/8/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Sepsis Hospitalization 8/5/2006 59 Female 143 lb 9/8/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Serotonin Syndrome Other Serious 9/23/2006 38 Female 225 lb 9/28/2006 Pharmacist United States
Primary
Concomitant
Vascular Calcification Life Threatening 10/15/2005 67 Male 183 lb 9/28/2006 United States
Primary
Concomitant
Tooth Abscess Other Serious 9/1/2005 60 Female 10/19/2006 Physician United Kingdom
Primary
Concomitant
Weight Increased Other Serious 9/9/2004 55 Female 10/20/2006 United States
Primary
Concomitant
Tongue Disorder Hospitalization 6/26/2006 44 Male 194 lb 10/27/2006 Other Health Professional France
Primary
Secondary
Concomitant
Serotonin Syndrome Other Serious 9/23/2006 38 Female 11/3/2006 Physician United States
Primary
Concomitant
Pulmonary Oedema Other Serious 6/30/2006 26 Female 11/13/2006 Other Health Professional United Kingdom
Primary
Concomitant
Staphylococcal Infection Other Serious 9/23/2006 38 Female 219 lb 11/30/2006 Physician United States
Primary
Concomitant
Venoocclusive Disease Other Serious 10/14/2006 11 Female 60 lb 11/30/2006 Physician Canada
Primary
Concomitant
Toxic Skin Eruption Other Serious 1/7/2006 64 Male 181 lb 1/2/2007 Physician France
Primary
Concomitant
Sepsis Hospitalization 1/12/2007 43 Female 2/23/2007 Other Health Professional United Kingdom
Primary
Concomitant
Sepsis Other Serious 1/12/2007 43 2/28/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Urticaria Required Intervention 12/3/2006 57 Male 289 lb 12/14/2006 United States
Primary
Concomitant
Torsade De Pointes Other Serious 3/6/2007 45 Male 165 lb 3/19/2007 Other Health Professional United States
Primary
Concomitant
Myocardial Infarction Death 2/24/2007 61 Female 148 lb 3/22/2007 United Kingdom
Primary
Concomitant
Sputum Retention Other Serious 3/18/2007 Female 200 lb 3/30/2007 Consumer United States
Primary
Concomitant
Lip Swelling Other Serious 2/1/2007 74 Male 236 lb 2/1/2007 Pharmacist United States
Primary
Concomitant
International Normalised Ratio Increased Other Serious 71 Female 5/3/2007
Primary
Secondary
Concomitant
Troponin I Increased Other Serious 2/25/2007 61 Female 148 lb 5/3/2007 Pharmacist United Kingdom
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 4/4/2007 55 Male 189 lb 5/29/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Troponin I Increased Other Serious 2/25/2007 61 Female 148 lb 6/8/2007 Pharmacist United Kingdom
Primary
Concomitant
Pseudomembranous Colitis Hospitalization 2/1/1999 35 Male 6/26/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Septic Shock Other Serious 2/25/2007 61 Female 148 lb 6/21/2007 Pharmacist United Kingdom
Primary
Concomitant
Blood Urea Increased Life Threatening 12/22/2006 Male 7/6/2007 United Kingdom
Primary
Concomitant
Pneumonia Other Serious 3/18/2007 Female 200 lb 7/18/2007 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 4/16/2007 84 Male 165 lb 8/4/2007 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Death 2/4/2006 80 Male 8/31/2007 Other Health Professional Australia
Primary
Secondary
Concomitant
Weight Decreased Other Serious 4/16/2007 84 Male 165 lb 8/31/2007 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 4/16/2007 84 Male 165 lb 8/31/2007 Physician United States
Primary
Concomitant
Skin Turgor Decreased Hospitalization 2/11/2007 82 Female 9/26/2007 Other Health Professional United States
Primary
Concomitant
Pulmonary Embolism Hospitalization 9/17/2007 69 Male 198 lb 9/28/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Life Threatening 9/23/2007 Male 192 lb 10/17/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Unresponsive To Stimuli Hospitalization 1/6/2007 60 Male 10/12/2007 Physician United States
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 4/13/2003 64 Male 11/28/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Osteonecrosis Hospitalization 12/21/2006 60 Male 10/29/2007 United States
Primary
Secondary
Concomitant
Vomiting Other Serious 8/3/2007 64 Male 11/5/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Staphylococcal Bacteraemia Life Threatening 10/7/2007 14 Male 203 lb 11/8/2007 Physician United States
Primary
Secondary
Concomitant
Jaundice Other Serious 10/5/2007 56 Female 227 lb 11/15/2007
Primary
Concomitant
Hepatitis Other Serious 8/3/2007 64 Male 11/12/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Other Serious 10/14/2006 11 Female 60 lb 11/8/2007 Physician Canada
Primary
Secondary
Concomitant
Hepatitis Other Serious 10/5/2007 56 Female 227 lb 11/16/2007 United Kingdom
Primary
Concomitant
Vomiting Life Threatening 10/28/2007 14 Female 126 lb 11/21/2007 Other Health Professional United States
Primary
Secondary
Concomitant
No Adverse Reaction 4/13/2003 Male 11/30/2007 Australia
Primary
Secondary
Concomitant
Skin Turgor Decreased Hospitalization 2/11/2007 82 Female 11/28/2007 Other Health Professional United States
Primary
Concomitant
Confusional State Hospitalization 10/25/2007 12/6/2007 Consumer United Kingdom
Primary
Concomitant
Vomiting Life Threatening 10/28/2007 14 Female 57 lb 12/24/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Sepsis Death 12/31/2007 65 Male 239 lb 1/10/2008 Physician United States
Primary
Secondary
Concomitant
Septic Shock Death 12/31/2007 65 Male 239 lb 1/16/2008 Physician United States
Primary
Secondary
Concomitant
Vomiting Life Threatening 1/1/2008 68 Male 198 lb 1/28/2008 Other Health Professional United Kingdom
Primary
Concomitant
Sepsis Death 12/31/2007 65 Male 239 lb 1/31/2008 Physician United States
Primary
Secondary
Concomitant
Vomiting Other Serious 8/3/2007 2/12/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Malaise Other Serious 8/3/2007 64 Male 2/6/2008 United Kingdom
Primary
Secondary
Concomitant
Hepatitis Other Serious 8/3/2007 64 Male 2/6/2008 United Kingdom
Primary
Secondary
Concomitant
Myocardial Infarction Death 2/24/2007 61 Female 148 lb 5/13/2008 Other Health Professional United Kingdom
Primary
Concomitant
Renal Failure Acute Hospitalization 8/17/2008 75 Female 176 lb 9/9/2008 Other Health Professional Germany
Primary
Secondary
Concomitant
Tubulointerstitial Nephritis Hospitalization 12/22/2006 Male 9/29/2008 United Kingdom
Primary
Concomitant
Respiratory Failure Life Threatening 6/24/2008 Female 163 lb 6/29/2008 Pharmacist United States
Primary
Concomitant
Weight Decreased Other Serious 11/1/2003 Female 185 lb 11/21/2008 United States
Primary
Secondary
Concomitant
Dyspnoea Hospitalization 71 Female 11/24/2008 Pharmacist United Kingdom
Primary
Concomitant
Hyperkalaemia 11/19/2008 Male 184 lb 12/10/2008 Physician United States
Primary
Concomitant
Renal Failure Acute Hospitalization 10/1/2007 Male 12/23/2008 Other Health Professional Norway
Primary
Secondary
Concomitant
Weight Increased Death 12/5/2008 69 Female 12/18/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Stevens-johnson Syndrome Hospitalization 7/6/2006 75 Male 12/18/2008 Other Health Professional Germany
Primary
Secondary
Rhabdomyolysis Hospitalization 10/1/2007 Male 12/29/2008 Other Health Professional Norway
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 10/1/2007 Male 1/21/2009 Other Health Professional Norway
Primary
Secondary
Concomitant
Optic Atrophy Other Serious 9/1/2008 2/13/2009 Other Health Professional United Kingdom
Primary
Concomitant
Weight Decreased Other Serious 11/1/2003 Female 185 lb 2/19/2009 United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 1/15/2009 68 Male 125 lb 2/19/2009 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 4/16/2007 Male 165 lb 3/4/2009 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 11/1/2003 Female 185 lb 3/5/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Sensation Of Heaviness Required Intervention 2/20/2009 59 Female 280 lb 3/17/2009 Pharmacist United States
Primary
Concomitant
Weight Decreased Other Serious 11/1/2003 Female 185 lb 4/9/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 4/1/2005 69 Male 12/4/2008 United States
Primary
Secondary
Concomitant
Drug Hypersensitivity Hospitalization 4/3/2009 4/17/2009 Physician Germany
Primary
Secondary
Concomitant
Rotavirus Test Positive Hospitalization 4/1/2009 72 Female 176 lb 7/20/2009 Physician Germany
Primary
Secondary
Concomitant
Drug Interaction Hospitalization 72 Female 176 lb 7/20/2009 Pharmacist Germany
Primary
Secondary
Concomitant
Vomiting 68 Male 8/4/2009 Consumer United States
Primary
Concomitant
Staphylococcal Infection Other Serious 66 Male 8/31/2009 Physician Portugal
Primary
Secondary
Concomitant
Staphylococcal Infection Other Serious 66 Male 9/4/2009 Portugal
Primary
Secondary
Concomitant
Graft Versus Host Disease Death 9/9/2008 Male 168 lb 9/9/2009 Physician United Kingdom
Primary
Concomitant
Vomiting Other Serious 10/1/2007 78 Female 9/21/2009 Lawyer United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 63 Male 180 lb 9/25/2009 United States
Primary
Concomitant
Urinary Hesitation Hospitalization 7/28/2008 65 Male 207 lb 10/6/2009 United States
Primary
Secondary
Concomitant
Urinary Hesitation Hospitalization 7/28/2008 65 Male 207 lb 10/5/2009 Physician United States
Primary
Secondary
Concomitant
Tubulointerstitial Nephritis Other Serious 2/12/2007 43 Female 10/8/2009 Other Health Professional United Kingdom
Primary
Concomitant
Haemoglobin Decreased Other Serious 1/1/2004 Male 205 lb 10/28/2009 Other Health Professional United States
Primary
Concomitant
Pain In Extremity Hospitalization 47 Male 10/27/2009 United States
Primary
Concomitant
Viral Infection Other Serious 1/1/1995 Male 205 lb 12/2/2009 Other Health Professional United States
Primary
Concomitant
Renal Failure Hospitalization 10/22/2009 Female 12/15/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2003 Male 250 lb 12/21/2009 Other Health Professional United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 10/22/2009 75 Female 12/18/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Blood Bilirubin Increased 10/21/2009 77 Male 161 lb 1/13/2010 Other Health Professional United States
Primary
Concomitant
Tooth Disorder Other Serious 1/1/2002 Male 1/15/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2003 Male 250 lb 2/3/2010 Other Health Professional United States
Primary
Concomitant
Oedema Hospitalization 9/17/2007 Male 198 lb 2/9/2010 Germany
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2003 Male 250 lb 2/12/2010 Other Health Professional United States
Primary
Concomitant
Wound Infection Staphylococcal Other Serious 8/1/2005 Male 2/22/2010 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 7/1/2003 Female 137 lb 3/1/2010 United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2003 Male 250 lb 3/1/2010 Other Health Professional United States
Primary
Concomitant
Viral Infection Other Serious 1/1/1995 Male 205 lb 3/4/2010 Other Health Professional United States
Primary
Concomitant
Vomiting Other Serious 75 Male 3/5/2010 Physician United States
Primary
Secondary
Concomitant
Staphylococcal Bacteraemia Other Serious 66 Male 3/11/2010 Other Health Professional Portugal
Primary
Secondary
Concomitant
Urosepsis Hospitalization 2/4/2009 72 Female 3/15/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Interacting
Weight Decreased Other Serious 7/1/2003 Female 137 lb 3/18/2010 United States
Primary
Concomitant
Vomiting Other Serious 75 Male 3/19/2010 Physician United States
Primary
Secondary
Concomitant
Vomiting Other Serious 75 Male 3/25/2010 Physician United States
Primary
Secondary
Concomitant
Tooth Disorder Other Serious 1/1/2002 Male 4/1/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Latent Tuberculosis Death 5/1/2006 65 Female 119 lb 4/27/2010 Physician Czech Republic
Primary
Concomitant
Tooth Disorder Other Serious 1/1/2002 Male 5/4/2010 United States
Primary
Secondary
Concomitant
Clostridium Difficile Colitis Hospitalization 3/1/2009 72 Female 176 lb 5/6/2010 Physician Germany
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Life Threatening 1/21/2009 45 Male 5/12/2010 Physician Germany
Primary
Secondary
Concomitant
Urosepsis Hospitalization 2/4/2009 72 Female 5/14/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Interacting
Clostridium Difficile Colitis Hospitalization 3/1/2009 72 Female 176 lb 5/17/2010 Physician Germany
Primary
Secondary
Concomitant
Urosepsis Hospitalization 2/4/2009 72 Female 5/20/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Interacting
Staphylococcal Infection Other Serious 66 Male 6/2/2010 Physician Portugal
Primary
Secondary
Concomitant
Macroglossia Other Serious 5/30/2010 87 Female 6/9/2010 Other Health Professional Italy
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 4/27/2010 53 Female 203 lb 6/10/2010 Physician Netherlands
Primary
Secondary
Concomitant
Acquired Macroglossia Other Serious 5/30/2010 87 Female 6/11/2010 Other Health Professional Italy
Primary
Secondary
Concomitant
Total Lung Capacity Decreased Other Serious 1/1/2002 65 Male 6/11/2010 United States
Primary
Secondary
Concomitant
Total Lung Capacity Decreased Other Serious 1/1/2002 65 Male 6/22/2010 United States
Primary
Secondary
Concomitant
Total Lung Capacity Decreased Other Serious 1/1/2002 65 Male 6/30/2010 United States
Primary
Secondary
Concomitant
Hyponatraemia Hospitalization 10/16/2009 67 Male 168 lb 7/6/2010 Physician Canada
Primary
Secondary
Concomitant
Pulmonary Arterial Hypertension Death Male 7/14/2010 Consumer United States
Primary
Concomitant
Weight Increased Other Serious 7/1/2010 54 Male 254 lb 7/20/2010 Consumer United States
Primary
Concomitant
Pulmonary Arterial Hypertension Death Male 7/29/2010 Other Health Professional United States
Primary
Concomitant
Acquired Macroglossia Other Serious 5/30/2010 87 Female 7/27/2010 Other Health Professional Italy
Primary
Secondary
Concomitant
Weight Decreased Other Serious 7/1/2003 21 Female 137 lb 8/6/2010 United States
Primary
Concomitant
Pyrexia Other Serious 1/9/2009 58 Female 97 lb 7/28/2010 Physician Japan
Primary
Concomitant
Total Lung Capacity Decreased Other Serious 1/1/2002 65 Male 8/18/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Cerebrovascular Accident Hospitalization 8/3/2010 62 Male 220 lb 8/26/2010 Other Health Professional United States
Primary
Concomitant
Respiratory Failure Life Threatening 4/27/2010 53 Female 203 lb 8/27/2010 Physician Netherlands
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2003 54 Male 250 lb 8/30/2010 Other Health Professional United States
Primary
Concomitant
Weight Decreased Other Serious 7/1/2003 21 Female 137 lb 9/2/2010 United States
Primary
Concomitant

Drug Data