Allopurinol combined with Metoprolol

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Cardiac Arrest Death 12/19/2005 83 Male 1/5/2006 Physician
Primary
Concomitant
Pyrexia Other Serious 11/26/2005 66 Female 128 lb 12/30/2005 Switzerland
Primary
Secondary
Concomitant
Vomiting Death 3/1/2005 88 Male 176 lb 1/20/2006 Other Health Professional United Kingdom
Primary
Concomitant
Myocardial Infarction Hospitalization 1/1/2000 74 Male 231 lb 1/20/2006 Lawyer United States
Primary
Concomitant
White Blood Cell Count Increased Other Serious 6/6/2001 68 Male 1/27/2006 Physician United States
Primary
Concomitant
Tachyarrhythmia Life Threatening 12/3/2005 Female 1/26/2006 France
Primary
Concomitant
Urinary Tract Infection Other Serious 81 Male 1/23/2006 Pharmacist Canada
Primary
Concomitant
Sudden Death Death 11/3/2005 Male 1/31/2006 Physician Poland
Primary
Secondary
Concomitant
Melaena Hospitalization 11/8/2005 65 Male 1/27/2006 Pharmacist United States
Primary
Concomitant
Ventricular Hypertrophy Other Serious 12/19/2005 83 Male 2/1/2006 Physician
Primary
Concomitant
Rhabdomyolysis Hospitalization 84 Male Pharmacist United States
Primary
Secondary
Concomitant
Lactic Acidosis Required Intervention 11/14/2005 57 Male 286 lb 1/24/2006 Pharmacist United States
Primary
Concomitant
Sepsis Other Serious 1/19/2006 70 Male 2/9/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Ventricular Fibrillation Other Serious 12/13/2000 57 Female 179 lb 2/27/2006 Physician Germany
Primary
Concomitant
Flatulence 12/1/2005 65 Male 2/27/2006 Consumer United States
Primary
Secondary
Concomitant
Respiratory Distress Life Threatening 8/19/2005 66 Male 3/1/2006 Physician Switzerland
Primary
Secondary
Concomitant
Vascular Bypass Graft Other Serious 2/10/2006 67 Male 3/8/2006 Other Health Professional United States
Primary
Concomitant
Catheter Related Complication Other Serious 3/3/2004 62 Male 209 lb 3/14/2006 Consumer Germany
Primary
Concomitant
Restlessness Hospitalization 2/24/2006 Male 3/9/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Vertigo Life Threatening 12/3/2005 Female 3/17/2006 Physician France
Primary
Concomitant
Tachycardia Other Serious 4/8/2003 50 Male 243 lb 3/17/2006 United States
Primary
Concomitant
Gallbladder Pain Other Serious 3/14/2006 65 Male 3/25/2006 Consumer Mexico
Primary
Concomitant
Transient Ischaemic Attack Other Serious 8/1/2002 40 Female 187 lb 3/28/2006 Physician United States
Primary
Concomitant
Myocardial Infarction Hospitalization 4/20/2003 57 Male 165 lb 3/29/2006 Lawyer United States
Primary
Concomitant
Ulcer Other Serious 1/1/1999 37 Female 165 lb 3/29/2006 Physician United States
Primary
Concomitant
Ulcer Other Serious 1/1/1999 37 Female 165 lb 4/3/2006 Physician United States
Primary
Concomitant
Skin Discolouration Hospitalization 3/16/2006 Female 250 lb 4/10/2006 Consumer
Primary
Concomitant
Fatigue Hospitalization 11/3/2005 Male 4/11/2006 Physician Czech Republic
Primary
Secondary
Concomitant
Ulcer Other Serious 1/1/1999 37 Female 165 lb 4/12/2006 Physician United States
Primary
Concomitant
Sudden Death Disability 11/3/2005 Male 4/14/2006 Physician Czech Republic
Primary
Secondary
Concomitant
Weight Loss Diet Other Serious 1/1/2001 58 Male 4/12/2006 United States
Primary
Concomitant
Renal Injury Hospitalization 1/1/2001 72 Male 172 lb 4/20/2006 Lawyer United States
Primary
Concomitant
Sudden Death Disability 11/3/2005 73 Male 4/21/2006 Physician Poland
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 6/6/2001 68 Male 4/21/2006 Physician United States
Primary
Concomitant
Tachycardia Hospitalization 5/7/2003 64 Female 205 lb 4/24/2006 Physician United States
Primary
Concomitant
Ventricular Fibrillation Other Serious 10/1/2000 57 Female 179 lb 4/26/2006 Physician Germany
Primary
Concomitant
White Blood Cell Count Decreased Death Female 262 lb 4/25/2006 United States
Primary
Secondary
Concomitant
Thrombosis Other Serious 10/6/2005 64 Female 203 lb 4/21/2006 Other Health Professional Germany
Primary
Secondary
Concomitant
Ureteric Injury Hospitalization 6/6/2001 67 Male 231 lb 5/1/2006 Physician United States
Primary
Concomitant
Reperfusion Arrhythmia Hospitalization 4/1/2003 57 Male 165 lb 5/4/2006 Physician United States
Primary
Concomitant
Pulmonary Congestion Other Serious 5/27/2003 69 Male 161 lb 5/12/2006 Lawyer United States
Primary
Concomitant
Weight Decreased Other Serious 7/14/1999 59 Male 161 lb 5/17/2006 Physician United States
Primary
Concomitant
Ventricular Tachycardia Hospitalization 69 Female 176 lb 6/8/2006 Canada
Primary
Concomitant
Dyspnoea Other Serious 5/1/2006 79 Female 6/14/2006 Physician United States
Primary
Concomitant
Prothrombin Time Prolonged Other Serious 5/8/2006 83 Female 135 lb 5/8/2006 Pharmacist United States
Primary
Concomitant
Toe Amputation Required Intervention 1/1/2006 74 Male 6/27/2006 Physician United States
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Life Threatening 5/19/2006 81 Male 110 lb 7/14/2006 Pharmacist United States
Primary
Concomitant
Fluid Retention Male 7/21/2006 Consumer United States
Primary
Concomitant
Tumour Necrosis Other Serious 11/1/2005 79 Male 160 lb 7/21/2006 United States
Primary
Concomitant
Renal Failure Acute Required Intervention 2/2/2005 74 Male 319 lb 5/24/2006 Other Health Professional United States
Primary
Concomitant
Cardiac Failure Other Serious 9/1/2005 75 Male 190 lb 7/14/2006 Physician Germany
Primary
Concomitant
Therapeutic Response Decreased Hospitalization 7/14/2006 Female 214 lb 8/2/2006 Physician United States
Primary
Concomitant
Wheezing Life Threatening 81 Male 8/2/2006 Pharmacist Canada
Primary
Concomitant
Urinary Tract Infection Life Threatening 81 Male 8/2/2006 Pharmacist Canada
Primary
Concomitant
Renal Impairment Hospitalization 74 Male 8/17/2006 Consumer France
Primary
Concomitant
Throat Tightness Other Serious 1/1/2004 Male 270 lb 8/18/2006 Consumer United States
Primary
Concomitant
Myopathy Disability 1/1/2006 59 Male 9/14/2006 Pharmacist United States
Primary
Concomitant
Hypertension 56 Male 236 lb 9/14/2006 Consumer United States
Primary
Concomitant
Neoplasm Progression Life Threatening 6/2/2006 Male 9/18/2006
Primary
Concomitant
Tumour Invasion Life Threatening 6/2/2006 Male 9/25/2006
Primary
Concomitant
Pancreatitis Hospitalization 7/18/2006 66 Male 168 lb 9/27/2006 Germany
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 10/12/2006 59 Male 10/13/2006 Pharmacist United States
Primary
Concomitant
Thrombosis Life Threatening 6/28/2006 78 Male 230 lb 8/25/2006 Pharmacist United States
Primary
Concomitant
Nodal Arrhythmia Death 7/26/2006 86 Female 8/25/2006 Pharmacist United States
Primary
Concomitant
Erysipelas Hospitalization 5/1/2006 64 Female 10/24/2006 Consumer Sweden
Primary
Concomitant
Renal Failure Acute Required Intervention 10/11/2006 77 Male 154 lb 11/6/2006 Germany
Primary
Concomitant
Stomatitis Hospitalization 2/18/2006 59 Male 139 lb 2/18/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Overdose 6/13/2007 78 Male 7/26/2007 United States
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 7/1/2007 Male 203 lb 9/26/2007 Physician Australia
Primary
Secondary
Concomitant
Tachycardia Hospitalization 70 Female 9/26/2007
Primary
Secondary
Concomitant
Proteinuria Other Serious 8/2/2006 28 Male 3/29/2007 Physician United States
Primary
Concomitant
Syncope Hospitalization 1/1/2007 Male 10/22/2007 Other Health Professional United States
Primary
Concomitant
Myocardial Infarction Death 6/26/2007 79 Male 10/26/2007 Physician Australia
Primary
Concomitant
Multiple Myeloma Hospitalization 5/4/2006 67 Male 172 lb 10/29/2007 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2007 Male 344 lb 11/1/2007 Consumer United States
Primary
Concomitant
Hypotension Other Serious 81 Male 11/19/2007 Other Health Professional Canada
Primary
Secondary
Viral Upper Respiratory Tract Infection Hospitalization 2/18/2006 59 Male 139 lb 11/16/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Pleural Effusion Hospitalization 5/30/2007 Female 161 lb 11/21/2007 United States
Primary
Concomitant
Acute Myocardial Infarction Life Threatening 6/3/2007 Male 11/21/2007 Physician Germany
Primary
Secondary
Concomitant
Pleural Effusion Hospitalization 10/23/2007 Male 154 lb 11/26/2007 Germany
Primary
Concomitant
Subdural Haematoma Other Serious 6/5/2007 78 Male 11/16/2007 Sweden
Primary
Secondary
Concomitant
Overdose 6/13/2007 78 Male 10/22/2007 United States
Primary
Secondary
Concomitant
Tachycardia Life Threatening 9/28/2007 21 Female 150 lb 11/21/2007 Consumer United States
Primary
Secondary
Concomitant
Pleural Effusion Hospitalization 10/23/2007 Male 154 lb 12/5/2007 Germany
Primary
Concomitant
Death Death 11/13/2007 Male 130 lb 12/6/2007 Consumer United Kingdom
Primary
Concomitant
Weight Decreased Other Serious 1/1/2007 Male 344 lb 12/3/2007 Consumer United States
Primary
Concomitant
Unresponsive To Stimuli Life Threatening 9/28/2007 21 Female 150 lb 12/3/2007 Physician United States
Primary
Secondary
Concomitant
Adverse Event 1/1/2007 Male 220 lb 12/14/2007 Consumer United States
Primary
Concomitant
Respiratory Rate Increased Hospitalization 12/4/2007 66 Female 210 lb 12/12/2007 Physician United States
Primary
Secondary
Concomitant
Drug Ineffective Male 12/21/2007 Consumer United States
Primary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 8/27/2007 81 Male 12/3/2007 Pharmacist United States
Primary
Secondary
Concomitant
Haematochezia Other Serious 6/1/2007 Female 270 lb 1/14/2008 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/1999 60 Female 1/25/2008 Other Health Professional United States
Primary
Concomitant
Pain In Extremity Hospitalization 1/1/1983 Female 2/7/2008 Consumer United States
Primary
Concomitant
Wrong Technique In Drug Usage Process Hospitalization 1/1/2004 79 Female 4/4/2008 Physician United States
Primary
Concomitant
Wrong Technique In Drug Usage Process Hospitalization 1/1/2004 79 Female 4/11/2008 Physician United States
Primary
Concomitant
Haemoglobin Decreased Other Serious 4/2/2008 Male 4/15/2008 Physician Germany
Primary
Concomitant
Wrong Technique In Drug Usage Process Life Threatening 1/1/2006 79 Female 150 lb 5/2/2008 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/1999 59 Female 5/28/2008 Other Health Professional United States
Primary
Concomitant
Death Death 4/22/2008 83 Male 5/29/2008 United States
Primary
Concomitant
Withdrawal Syndrome Other Serious 1/1/2003 Female 120 lb 6/12/2008 Physician United States
Primary
Concomitant
Wound Complication Other Serious 1/1/2000 Female 6/4/2008 Physician United States
Primary
Concomitant
Heart Rate Decreased Life Threatening 4/22/2008 Male 111 lb 4/24/2008 United States
Primary
Concomitant
Hypophosphataemia Hospitalization 4/17/2008 59 Male 216 lb 6/26/2008 Consumer United States
Primary
Secondary
Concomitant
Atrial Fibrillation Other Serious 4/1/2008 Male 6/30/2008 Physician United Kingdom
Primary
Concomitant
Renal Impairment Hospitalization 4/8/2008 72 Female 146 lb 6/29/2008 Pharmacist United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 6/28/2008 Male 7/14/2008 Physician Poland
Primary
Concomitant
Vertigo Hospitalization 1/1/2008 Male 7/8/2008 Consumer United States
Primary
Concomitant
Tachycardia Death 3/31/2008 Male 183 lb 8/1/2008 Physician United States
Primary
Secondary
Concomitant
Hepatitis Hospitalization 6/4/2008 65 Female 8/22/2008 Other Health Professional Sweden
Primary
Concomitant
Weight Decreased Hospitalization 1/1/2008 Female 291 lb 9/11/2008 Consumer United States
Primary
Concomitant
Urinary Retention Hospitalization 7/28/2008 65 Male 207 lb 11/11/2008 United States
Primary
Secondary
Concomitant
Mental Status Changes Required Intervention 6/6/2008 51 Male 205 lb 10/25/2008 Pharmacist United States
Primary
Concomitant
Urinary Retention Hospitalization 7/28/2008 65 Male 207 lb 12/1/2008 United States
Primary
Secondary
Concomitant
Vision Blurred 4/1/2006 79 Male 12/1/2008 Germany
Primary
Secondary
Concomitant
Back Pain Hospitalization 11/17/2008 12/11/2008 Other Health Professional Germany
Primary
Secondary
Concomitant
Rash 7/1/2008 Female 267 lb 12/12/2008 Physician United States
Primary
Concomitant
Cardiac Arrest Death 8/18/2008 Male 144 lb 12/16/2008 Consumer United States
Primary
Concomitant
Thrombocytopenia Other Serious 1/16/2008 65 Male 238 lb 12/23/2008 Pharmacist United States
Primary
Concomitant
Weight Increased Death 12/5/2008 69 Female 12/18/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Drug Toxicity Death 50 Male 12/24/2008 Physician United States
Primary
Secondary
Pneumonia Hospitalization 2/11/2008 Male 12/24/2008 Physician United Kingdom
Primary
Concomitant
Completed Suicide Death 1/1/2007 50 Male 12/24/2008 Physician
Primary
Secondary
Completed Suicide Death 50 Male 12/29/2008 Pharmacist United States
Primary
Secondary
Anaemia Other Serious Male 12/31/2008 Physician United States
Primary
Concomitant
Xanthopsia Hospitalization 73 Female 166 lb 12/23/2008 United States
Primary
Concomitant
Rash Pruritic 9/6/2008 Male 201 lb 1/6/2009 Physician United States
Primary
Concomitant
Corneal Oedema Other Serious 5/27/2008 Male 154 lb 1/7/2009 Physician United States
Primary
Concomitant
Melaena Other Serious 12/30/2008 Male 150 lb 12/31/2008 Consumer United States
Primary
Secondary
Concomitant
Hallucination, Visual 9/1/2008 65 Male 12/2/2008 Consumer United States
Primary
Concomitant
Multiple Drug Overdose Intentional Death 50 Male 1/7/2009 Physician United States
Primary
Secondary
Duodenal Ulcer Haemorrhage Other Serious 4/15/2008 84 Female 1/15/2009 Consumer Germany
Primary
Concomitant
Drug Ineffective Other Serious Male 1/26/2009 Physician United States
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 12/30/2008 73 Male 150 lb 1/21/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Intentional Overdose Death 50 Male 1/27/2009 Physician United States
Primary
Secondary
Completed Suicide Death 1/29/2009 Other Health Professional United States
Primary
Secondary
Vitamin B12 Deficiency Other Serious 6/1/2007 Male 219 lb 2/11/2009 Physician United States
Primary
Secondary
Concomitant
Intervertebral Disc Displacement Hospitalization 8/26/2008 47 Female 202 lb 2/9/2009 Other Health Professional United States
Primary
Concomitant
Dyspnoea Hospitalization 1/1/2009 Male 2/24/2009 Physician United States
Primary
Concomitant
Dyspepsia Male 2/24/2009 United States
Primary
Concomitant
Skin Burning Sensation Male 2/24/2009 United States
Primary
Concomitant
Diarrhoea Hospitalization 2/1/2009 79 Male 2/25/2009 Consumer United States
Primary
Secondary
Concomitant
Lymph Node Tuberculosis Hospitalization 1/23/2009 48 Male 188 lb 2/25/2009 Physician Germany
Primary
Concomitant
Muscular Weakness Other Serious Female 2/25/2009 Consumer United States
Primary
Concomitant
Hyperglycaemia Hospitalization 2/20/2009 75 Female 168 lb 3/6/2009 Physician Hong Kong
Primary
Concomitant
Cardiac Arrest Death 2/16/2009 43 Male 3/6/2009 Consumer Philippines
Primary
Concomitant
Tendon Disorder Other Serious 1/1/2005 72 Female 139 lb 3/9/2009 Physician United States
Primary
Concomitant
Ocular Hyperaemia Other Serious Female 3/10/2009 Consumer United States
Primary
Concomitant
Ocular Hyperaemia Other Serious Female 3/11/2009 Consumer United States
Primary
Concomitant
Myocardial Infarction Other Serious 1/27/2007 3/12/2009 Other Health Professional Germany
Primary
Concomitant

Drug Data