Allopurinol combined with Metoprolol Succinate

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Aortic Valve Stenosis Hospitalization 70 Male 1/9/2006 Physician Norway
Primary
Concomitant
Renal Failure Hospitalization 11/1/2005 62 Male 2/3/2006 Sweden
Primary
Concomitant
Sick Sinus Syndrome Required Intervention 6/21/2005 70 Male 181 lb 4/13/2006 Physician Germany
Primary
Concomitant
Ill-defined Disorder Hospitalization 2/6/2006 82 207 lb 3/30/2006 Pharmacist United States
Primary
Secondary
Concomitant
Metastases To Central Nervous System Hospitalization 4/3/2006 53 Male 176 lb 4/19/2006 Germany
Primary
Concomitant
Skin Discolouration Hospitalization 3/16/2006 Female 250 lb 5/5/2006 Consumer
Primary
Concomitant
Vomiting Hospitalization 5/1/2006 71 Female 88 lb 5/23/2006 United States
Primary
Concomitant
Toe Amputation Required Intervention 1/1/2006 74 Male 5/30/2006 Physician United States
Primary
Concomitant
Skin Ulcer Required Intervention 5/24/2006 74 Male 5/30/2006 Physician United States
Primary
Concomitant
Vomiting Hospitalization 5/1/2006 71 Female 88 lb 6/7/2006 United States
Primary
Concomitant
Cardiac Failure Other Serious 9/1/2005 75 Male 190 lb 5/3/2006 Physician Germany
Primary
Concomitant
Vomiting Hospitalization 5/1/2006 71 Female 88 lb 7/5/2006 United States
Primary
Concomitant
Hypoglycaemia Hospitalization 4/14/2006 76 Male 7/11/2006 Sweden
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 1/24/2006 Unknown 6/28/2006 Physician United States
Primary
Concomitant
Fall Other Serious 3/23/2006 Male 291 lb 9/7/2006 Physician Germany
Primary
Concomitant
Cerebral Infarction Hospitalization 2/22/2006 73 Female 192 lb 9/22/2006
Primary
Concomitant
Vomiting Hospitalization 8/2/2006 75 Female 187 lb 10/2/2006 Physician Germany
Primary
Concomitant
Renal Failure Acute Other Serious 11/15/2005 Male 10/12/2006 Other Health Professional France
Primary
Concomitant
Cerebral Infarction Hospitalization 2/22/2006 73 Female 192 lb 11/6/2006
Primary
Concomitant
Cerebral Infarction Hospitalization 2/22/2006 73 Female 192 lb 11/14/2006
Primary
Concomitant
Respiratory Disorder Life Threatening 63 Male 331 lb 11/21/2006 Pharmacist United States
Primary
Secondary
Concomitant
Somnolence Hospitalization 11/7/2006 68 Male 124 lb 11/21/2006 Physician New Zealand
Primary
Secondary
Concomitant
Mouth Haemorrhage Death 8/4/2005 47 Male 11/22/2006 Pharmacist United States
Primary
Concomitant
Renal Failure Chronic Hospitalization 9/5/2006 72 Female 12/6/2006 Other Health Professional Switzerland
Primary
Secondary
Concomitant
International Normalised Ratio Increased Hospitalization 11/27/2006 59 Male 223 lb 11/30/2006 Pharmacist United States
Primary
Concomitant
Rheumatoid Arthritis Other Serious 1/1/2003 Female 12/13/2006 Physician United States
Primary
Concomitant
Renal Failure Chronic Hospitalization 9/5/2006 72 Female 12/20/2006 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Pharmaceutical Product Complaint Female 301 lb 12/22/2006 Physician United States
Primary
Secondary
Concomitant
Vertigo Death 10/24/2006 71 Male 1/3/2007 Physician United States
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 5/1/2006 1/16/2007 Sweden
Primary
Secondary
Concomitant
Weight Decreased 1/1/2006 72 Male 265 lb 10/16/2006 Consumer United States
Primary
Concomitant
Nausea Other Serious 70 Male 210 lb 11/17/2005 United States
Primary
Concomitant
Hypoglycaemia Hospitalization 1/19/2007 66 Male 3/1/2007 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Orthopnoea Hospitalization 1/1/2007 62 Male 159 lb 3/7/2007 Physician Switzerland
Primary
Concomitant
Myocardial Infarction Other Serious 1/27/2007 60 Male 194 lb 3/14/2007 Germany
Primary
Concomitant
Coronary Artery Stenosis Hospitalization 6/23/2005 50 Male 276 lb 3/12/2007 United States
Primary
Secondary
Concomitant
Syncope Hospitalization 1/1/2007 Male 3/20/2007 Other Health Professional United States
Primary
Concomitant
Skin Hyperpigmentation Hospitalization 4/1/2004 Male 3/26/2007 Other Health Professional Germany
Primary
Concomitant
Tooth Disorder Other Serious 10/1/2006 73 Male 3/27/2007 Other Health Professional Sweden
Primary
Concomitant
Weight Decreased Hospitalization 2/18/2007 82 Male 147 lb 3/26/2007 Pharmacist United States
Primary
Concomitant
Weight Decreased 10/1/2006 48 Male 220 lb 12/11/2006 Consumer United States
Primary
Concomitant
Surgery Life Threatening 12/1/2006 56 Male 205 lb 4/3/2007 United States
Primary
Concomitant
Urine Output Decreased Hospitalization 3/9/2007 89 Male 156 lb 3/29/2007 Pharmacist United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 3/26/2006 Male 198 lb 4/3/2007 Germany
Primary
Concomitant
Drug Effect Decreased 9/1/2006 76 Male 220 lb 1/12/2007 Consumer United States
Primary
Concomitant
Pulmonary Oedema Hospitalization 3/25/2007 84 Female 123 lb 4/9/2007 United States
Primary
Concomitant
Ventricular Dysfunction Other Serious 2/26/2007 Male 173 lb 4/11/2007 Physician United States
Primary
Concomitant
Leukocytosis Other Serious 2/1/2007 Male 181 lb 4/12/2007 Physician United States
Primary
Concomitant
International Normalised Ratio Increased Hospitalization 3/20/2007 52 Male 4/9/2007 Denmark
Primary
Concomitant
Death Death 11/2/2006 Female 195 lb 4/18/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Urticaria Life Threatening 3/1/2006 65 Male 241 lb 4/25/2007 Physician United States
Primary
Secondary
Concomitant
Tachyarrhythmia Death 11/2/2006 Female 195 lb 4/26/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Sudden Death Disability 11/3/2005 73 Male 4/27/2007 Physician Poland
Primary
Secondary
Concomitant
Loss Of Consciousness Other Serious 3/22/2007 Male 5/2/2007 Physician
Primary
Concomitant
Tachyarrhythmia Other Serious 1/1/2003 Male 5/8/2007 Consumer Germany
Primary
Secondary
Concomitant
Myelodysplastic Syndrome Other Serious 1/1/2007 59 Male 234 lb 5/9/2007 Physician United States
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 7/19/2003 51 Male 2/21/2007 United States
Primary
Secondary
Concomitant
Multi-organ Failure Death 11/2/2006 Female 195 lb 5/15/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Hyponatraemia Hospitalization 3/5/2007 78 Male 5/18/2007
Primary
Secondary
Concomitant
Myelodysplastic Syndrome Other Serious 1/15/2007 59 Male 234 lb 5/24/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Sudden Death Disability 11/3/2005 73 Male 5/25/2007 Physician Poland
Primary
Secondary
Concomitant
Leukocytosis Other Serious 2/1/2007 Male 181 lb 5/29/2007 Physician United States
Primary
Concomitant
Secondary Adrenocortical Insufficiency Hospitalization 11/7/2006 41 Male 179 lb 5/30/2007 Physician Netherlands
Primary
Concomitant
Myelodysplastic Syndrome Other Serious 2/22/2007 Male 233 lb 5/30/2007 Physician United States
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Hospitalization 1/2/2007 88 Female 4/25/2007 Pharmacist United States
Primary
Secondary
Concomitant
Scleroderma Other Serious 6/1/2005 66 Male 190 lb 6/1/2007 Physician United States
Primary
Concomitant
Somnolence 1/1/2007 82 Male 160 lb 4/12/2007 Consumer United States
Primary
Concomitant
Viral Infection Hospitalization 4/15/2007 Male 185 lb 6/6/2007 Physician Switzerland
Primary
Concomitant
Respiratory Distress Life Threatening 7/1/2006 67 Male 6/7/2007 Physician United States
Primary
Secondary
Concomitant
Reversible Posterior Leukoencephalopathy Syndrome Hospitalization 71 6/8/2007 Germany
Primary
Concomitant
Renal Failure Acute Hospitalization 4/16/2007 84 Male 165 lb 6/11/2007 Physician United States
Primary
Concomitant
Pleural Effusion Hospitalization 5/30/2007 Female 161 lb 6/21/2007 United States
Primary
Concomitant
Hepatic Enzyme Increased Other Serious 5/29/2007 37 Male 292 lb 6/18/2007 Pharmacist United States
Primary
Concomitant
Syncope Other Serious 4/30/2007 72 Male 75 lb 6/22/2007 Physician United Kingdom
Primary
Concomitant
Medication Residue 82 Female 169 lb 6/25/2007 United States
Primary
Concomitant
Stevens-johnson Syndrome Other Serious 2/28/2007 69 Male 6/19/2007 United States
Primary
Concomitant
Subdural Haematoma Hospitalization 11/13/2006 72 Male 6/29/2007 Consumer Australia
Primary
Concomitant
Urinary Retention Hospitalization 1/17/2007 70 Male 6/27/2007 Physician Germany
Primary
Concomitant
Interacting
Sudden Death Disability 11/3/2005 73 Male 7/11/2007 Physician Poland
Primary
Secondary
Concomitant
Syncope Other Serious 4/30/2007 72 Male 75 lb 7/11/2007 Physician United Kingdom
Primary
Concomitant
Haemoptysis Other Serious 7/27/2005 Male 203 lb 7/13/2007 Consumer Hungary
Primary
Secondary
Concomitant
Vascular Graft Other Serious 1/1/1993 72 Female 205 lb 7/17/2007 United States
Primary
Secondary
Concomitant
Syncope Other Serious 4/30/2007 72 Male 75 lb 7/27/2007 Physician United Kingdom
Primary
Concomitant
Renal Failure Other Serious 82 Male 161 lb 7/30/2007 Physician Germany
Primary
Secondary
Concomitant
Stomatitis Hospitalization 6/28/2007 61 Male 7/30/2007 Physician Germany
Primary
Concomitant
Renal Failure Hospitalization 1/10/2007 73 Male 8/2/2007 Other Health Professional Australia
Primary
Secondary
Concomitant
Gastroenteritis Hospitalization 4/15/2007 Male 185 lb 8/3/2007 Physician Switzerland
Primary
Concomitant
Pyrexia Hospitalization 1/1/2005 Male 8/3/2007 Physician Austria
Primary
Concomitant
Weight Decreased Other Serious 4/16/2007 84 Male 165 lb 8/4/2007 Physician United States
Primary
Secondary
Concomitant
Somnolence 1/1/2005 68 Male 230 lb 7/10/2007 Consumer United States
Primary
Secondary
Concomitant
Syncope Hospitalization 6/18/2006 74 Male 8/3/2007 Pharmacist United States
Primary
Secondary
Concomitant
Myocardial Infarction Death 5/28/2007 77 Male 8/10/2007 Physician Sweden
Primary
Concomitant
Renal Impairment Hospitalization 1/1/2007 Male 240 lb 8/10/2007 Physician United States
Primary
Concomitant
Drug Interaction Death 74 Female 8/16/2007 Sweden
Primary
Secondary
Concomitant
Interacting
Blood Glucose Increased Hospitalization 7/17/2007 83 Male 8/17/2007 Consumer United States
Primary
Concomitant
Rhabdomyolysis Other Serious 6/11/2007 Male 8/17/2007 Other Health Professional Germany
Primary
Concomitant
Myocardial Infarction Death 5/28/2007 77 Male 8/17/2007 Physician Sweden
Primary
Concomitant
General Physical Health Deterioration Hospitalization 7/21/2006 53 Male 150 lb 8/23/2007 Physician United Kingdom
Primary
Concomitant
Blood Pressure Increased 5/1/2007 61 Male 8/28/2007 Consumer United States
Primary
Concomitant
Blood Pressure Increased 5/1/2007 61 Male 8/28/2007 Consumer United States
Primary
Concomitant
Orthopnoea Hospitalization 1/1/2007 62 Male 159 lb 8/31/2007 Physician Switzerland
Primary
Concomitant
Weight Decreased Other Serious 4/16/2007 84 Male 165 lb 8/31/2007 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 4/16/2007 84 Male 165 lb 8/31/2007 Physician United States
Primary
Concomitant
Pemphigoid Hospitalization 5/26/2007 81 Male 9/4/2007 Physician Sweden
Primary
Concomitant
Orthopnoea Other Serious 4/30/2004 55 Male 226 lb 9/5/2007 Physician Canada
Primary
Concomitant
Hallucination, Visual Other Serious 12/12/2006 51 Male 279 lb 9/6/2007 Consumer United States
Primary
Concomitant
Gastroenteritis Hospitalization 4/15/2007 Male 185 lb 9/7/2007 Physician Switzerland
Primary
Concomitant
Nervous System Disorder Other Serious 6/10/2007 Male 201 lb 9/7/2007 Physician United States
Primary
Secondary
Concomitant
Syncope Other Serious 4/30/2007 72 Male 163 lb 9/10/2007 Physician United Kingdom
Primary
Concomitant
Venous Stenosis Hospitalization 8/9/2007 Male 193 lb 9/5/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Infarction Hospitalization 8/13/2007 52 Male 163 lb 9/6/2007 Australia
Primary
Concomitant
Sepsis Hospitalization 2/6/2006 Male 128 lb 9/21/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Cerebrovascular Accident Hospitalization 8/28/2007 63 Male 225 lb 9/19/2007 Physician Germany
Primary
Concomitant
Drug Level Fluctuating Death Female 9/26/2007 Other Health Professional Germany
Primary
Secondary
Concomitant
Pyrexia Hospitalization 1/1/2005 Male 9/28/2007 Physician Austria
Primary
Concomitant
Back Pain 2/27/2007 56 Male 262 lb 9/20/2007 Other Health Professional United States
Primary
Concomitant
Drug Level Fluctuating Death Male 9/29/2007 Other Health Professional Germany
Primary
Secondary
Concomitant
Myocardial Infarction Death 5/28/2007 77 Male 10/20/2007 Physician Sweden
Primary
Concomitant
Sick Sinus Syndrome Hospitalization 6/10/2007 72 Male 10/22/2007 Physician Sweden
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 2/22/2007 80 Male 180 lb 2/26/2007 Pharmacist United States
Primary
Secondary
Concomitant
Syncope Hospitalization 3/28/2007 72 Male 163 lb 12/12/2007 Physician Germany
Primary
Concomitant
Paraesthesia 6/1/2007 Female 214 lb 12/14/2007 Consumer United States
Primary
Concomitant
Urinary Tract Infection Other Serious 69 Female 154 lb 12/27/2007 Physician Germany
Primary
Secondary
Concomitant
Vomiting Hospitalization 67 Male 1/15/2008 Other Health Professional Australia
Primary
Secondary
Concomitant
Paraesthesia 10/23/2007 Male 280 lb 1/15/2008 Consumer United States
Primary
Concomitant
Abscess Hospitalization 10/1/2007 Male 1/18/2008 Other Health Professional Sweden
Primary
Secondary
Concomitant
Stevens-johnson Syndrome Death 4/19/2005 80 Female 1/22/2008 Physician Germany
Primary
Secondary
Concomitant
Stevens-johnson Syndrome Death 4/19/2005 Female 1/25/2008 Physician Germany
Primary
Secondary
Concomitant
Malaise Hospitalization 12/20/2007 63 Male 2/11/2008 Physician Germany
Primary
Concomitant
Pharmaceutical Product Counterfeit Other Serious 7/25/2007 66 Male 224 lb 12/3/2007 United States
Primary
Concomitant
Toxic Epidermal Necrolysis Death 3/17/2005 54 Female 2/13/2008 Physician Germany
Primary
Secondary
Concomitant
Agranulocytosis Hospitalization 8/31/2007 Male 2/25/2008 Other Health Professional Germany
Primary
Secondary
Concomitant
Swollen Tongue Death 11/4/2004 Female 3/14/2008 Germany
Primary
Secondary
Concomitant
Muscle Injury Other Serious 3/1/2008 56 Male 232 lb 3/20/2008 Consumer United States
Primary
Concomitant
Rash Hospitalization 7/25/2007 69 Male 168 lb 4/1/2008 Other Health Professional Australia
Primary
Secondary
Concomitant
Rash Hospitalization 7/25/2007 4/15/2008 Australia
Primary
Secondary
Concomitant
Swollen Tongue Death 11/4/2004 Female 4/18/2008 Germany
Primary
Secondary
Concomitant
Leukopenia Other Serious 5/12/2006 62 Female 185 lb 4/29/2008 Physician Germany
Primary
Secondary
Concomitant
Chest Pain Life Threatening 5/8/2008 63 Male 5/14/2008 Sweden
Primary
Concomitant
Syncope Hospitalization 3/28/2007 72 Male 163 lb 4/9/2008 Physician Germany
Primary
Concomitant
Impaired Work Ability Life Threatening 2/1/2008 63 Male 128 lb 6/5/2008 Sweden
Primary
Concomitant
Po2 Decreased Hospitalization 8/1/2007 84 Male 205 lb 6/17/2008 United States
Primary
Secondary
Concomitant
Blood Glucose Increased Hospitalization 3/17/2008 77 Male 175 lb 4/30/2008 United States
Primary
Concomitant
Weight Decreased Other Serious 1/10/2007 60 Male 149 lb 6/23/2008 United States
Primary
Concomitant
Weight Decreased Hospitalization 1/1/2005 Male 200 lb 7/1/2008 Consumer United States
Primary
Concomitant
Swelling Face Hospitalization 6/20/2008 Female 320 lb 7/2/2008 United States
Primary
Concomitant
Skin Discolouration Other Serious 4/14/2008 71 Male 229 lb 7/23/2008 Consumer United States
Primary
Concomitant
Therapeutic Response Unexpected With Drug Substitution Hospitalization 7/4/2008 50 Male 7/15/2008 United States
Primary
Concomitant
Renal Failure Acute Other Serious 1/1/2008 77 Female 176 lb 7/28/2008 Physician Germany
Primary
Concomitant
Weight Decreased Required Intervention 10/15/2007 60 Male 153 lb 7/24/2008 United States
Primary
Concomitant

Drug Data