Allopurinol combined with Metformin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Thrombocytopenic Purpura Hospitalization 8/14/2002 Male 1/4/2006 Australia
Primary
Concomitant
Biliary Colic Hospitalization 2/25/2002 Male 1/4/2006 New Zealand
Primary
Concomitant
Thrombophlebitis Superficial Other Serious 7/24/2002 Male 1/4/2006 Australia
Primary
Concomitant
Pulmonary Embolism Life Threatening 6/1/1999 Female 1/4/2006 New Zealand
Primary
Concomitant
Pneumothorax Hospitalization 3/2/2002 Male 1/4/2006 France
Primary
Concomitant
Weight Decreased Hospitalization 4/11/2001 Female 1/4/2006 New Zealand
Primary
Concomitant
Renal Cyst Hospitalization 7/16/2004 Male 1/4/2006 France
Primary
Concomitant
Sepsis Hospitalization 5/28/2005 73 Male 196 lb 1/9/2006 Other Health Professional France
Primary
Secondary
Tachycardia Paroxysmal Hospitalization 6/6/2005 61 Male 300 lb 1/11/2006 United States
Primary
Concomitant
Sepsis Hospitalization 9/1/2005 65 Female 1/20/2006 Switzerland
Primary
Secondary
Concomitant
Renal Failure Required Intervention 8/25/2005 61 Male 11/15/2005 Other Health Professional United States
Primary
Concomitant
Lactic Acidosis Required Intervention 11/14/2005 57 Male 286 lb 1/24/2006 Pharmacist United States
Primary
Concomitant
Weight Decreased Hospitalization 10/24/2005 58 Male 203 lb 12/1/2005 Pharmacist United States
Primary
Concomitant
Ischaemic Stroke Hospitalization 9/1/2004 77 Female 190 lb 2/16/2006 Physician United States
Primary
Concomitant
Prothrombin Time Prolonged Hospitalization 9/1/2005 65 Female 2/7/2006 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Pseudoaldosteronism Hospitalization 1/1/2005 63 Male 150 lb 2/17/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Chest Pain Hospitalization 10/27/2005 60 Male 189 lb 1/16/2006 Pharmacist United States
Primary
Concomitant
Flatulence 12/1/2005 65 Male 2/27/2006 Consumer United States
Primary
Secondary
Concomitant
Blood Glucose Increased 1/1/2006 Male 2/27/2006 Consumer United States
Primary
Concomitant
Erectile Dysfunction 11/1/2005 70 Male 12/28/2005 Consumer United States
Primary
Concomitant
Catheter Related Complication Other Serious 3/3/2004 62 Male 209 lb 3/14/2006 Consumer Germany
Primary
Concomitant
Death Death 3/2/2006 Female 3/15/2006 Physician Canada
Primary
Concomitant
Sepsis Hospitalization 5/28/2005 73 Male 196 lb 3/17/2006 Other Health Professional France
Primary
Secondary
Poor Peripheral Circulation Other Serious 1/1/2005 76 Female 170 lb 3/10/2006 United States
Primary
Concomitant
Sepsis Hospitalization 9/1/2005 65 Female 3/14/2006 Switzerland
Primary
Secondary
Concomitant
Renal Failure Life Threatening 1/23/2006 Male 192 lb 3/24/2006 Physician Germany
Primary
Concomitant
Hypoaesthesia Hospitalization 7/1/2000 59 Male 236 lb 3/28/2006 Lawyer United States
Primary
Concomitant
Somnolence Other Serious 7/1/2005 60 Female 3/29/2006 Physician Germany
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 1/1/2006 51 Male 278 lb 3/21/2006 Physician United States
Primary
Concomitant
Renal Failure Hospitalization 8/25/2005 61 Male 3/24/2006 Other Health Professional United States
Primary
Concomitant
Weight Decreased 11/1/2005 58 Male 190 lb 1/20/2006 Consumer United States
Primary
Concomitant
Visual Disturbance 11/8/2005 65 Male 340 lb 1/20/2006 Other Health Professional United States
Primary
Concomitant
Pain Death 75 Female 4/5/2006 Physician Canada
Primary
Concomitant
Wound Infection Pseudomonas Hospitalization 5/1/2000 72 Female 231 lb 4/7/2006 Physician United States
Primary
Concomitant
Weight Decreased 7/1/2005 48 Male 230 lb 1/20/2006 Consumer United States
Primary
Concomitant
Headache 12/11/2005 67 Female 290 lb 1/20/2006 Consumer United States
Primary
Concomitant
Skin Discolouration Hospitalization 3/16/2006 Female 250 lb 4/10/2006 Consumer
Primary
Concomitant
Vomiting 12/14/2005 65 Male 217 lb 1/20/2006 Consumer United States
Primary
Concomitant
Weight Decreased 1/1/2005 51 Male 252 lb 1/20/2006 Consumer United States
Primary
Concomitant
Rectal Haemorrhage Other Serious 3/11/2006 72 Male 4/12/2006 Consumer United States
Primary
Concomitant
Circulatory Collapse Hospitalization 1/18/2006 67 Male 165 lb 4/13/2006 Physician Germany
Primary
Concomitant
Syncope Other Serious 65 Male 4/12/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Pain Hospitalization 2/28/2006 68 Male 4/14/2006 Physician United States
Primary
Concomitant
Weight Increased 9/14/2005 63 Female 225 lb 4/14/2006 Physician United States
Primary
Concomitant
Polytraumatism Hospitalization 3/1/2002 59 Male 236 lb 5/3/2006 Physician United States
Primary
Concomitant
Sepsis Hospitalization 9/1/2005 65 Female 5/1/2006 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Somnolence Other Serious 8/2/2005 Female 5/5/2006 Physician Germany
Primary
Secondary
Concomitant
Skin Discolouration Hospitalization 3/16/2006 Female 250 lb 5/5/2006 Consumer
Primary
Concomitant
Syncope Other Serious 65 Male 5/8/2006 Consumer United Kingdom
Primary
Secondary
Concomitant
Thrombin Time Prolonged Life Threatening 9/7/2005 63 Male 175 lb 5/9/2006 Physician Hungary
Primary
Secondary
Concomitant
Syncope Other Serious 65 Male 5/17/2006 Consumer United Kingdom
Primary
Secondary
Concomitant
Syncope Other Serious 65 Male 5/17/2006 Consumer United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 1/23/2006 67 Male 163 lb 5/22/2006 Physician Germany
Primary
Concomitant
Vision Blurred Other Serious 4/27/2006 59 Female 5/23/2006 Consumer Canada
Primary
Concomitant
Syncope Other Serious 65 Male 5/26/2006 Consumer United Kingdom
Primary
Secondary
Concomitant
Malaise Hospitalization 7/13/2005 80 Male 5/31/2006 Physician France
Primary
Concomitant
Urticaria Generalised Hospitalization 2/20/2005 54 Female 130 lb 5/25/2006 Other Health Professional United Kingdom
Primary
Concomitant
Heart Rate Irregular Other Serious 1/1/2006 63 Male 226 lb 5/30/2006 United States
Primary
Concomitant
Drug Interaction Other Serious Unknown 4/20/2006 Physician United States
Primary
Secondary
Syncope Vasovagal Hospitalization 7/13/2005 80 Male 6/14/2006 Physician France
Primary
Concomitant
Non-hodgkin's Lymphoma Other Serious 10/1/2003 Female 294 lb 6/15/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Prothrombin Level Decreased Other Serious 1/10/2000 75 Male 6/14/2006 Canada
Primary
Secondary
Concomitant
Prothrombin Level Decreased Other Serious 1/25/2000 74 Male 6/21/2006 Canada
Primary
Secondary
Concomitant
Medication Error 2/18/2006 59 Female 4/17/2006 Consumer United States
Primary
Concomitant
Syncope Vasovagal Hospitalization 7/13/2005 80 Male 7/6/2006 Physician France
Primary
Concomitant
Renal Failure Life Threatening 4/16/2006 70 Male 7/14/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Failure Death 4/16/2006 70 Male 7/14/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Failure Life Threatening 4/16/2006 70 Male 7/12/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vision Blurred 61 Male 7/21/2006 Consumer United States
Primary
Concomitant
Blood Glucose Increased 5/1/2005 68 Female 7/21/2006 Consumer United States
Primary
Secondary
Concomitant
Drug Ineffective 61 Male 7/21/2006 Consumer United States
Primary
Concomitant
Blood Glucose Increased 41 Male 7/21/2006 Consumer United States
Primary
Concomitant
Tumour Necrosis Other Serious 11/1/2005 79 Male 160 lb 7/21/2006 United States
Primary
Concomitant
Tremor Other Serious 3/1/2006 63 Male 220 lb 7/21/2006 Brazil
Primary
Secondary
Concomitant
Renal Failure Life Threatening 4/16/2006 70 Male 7/21/2006 United Kingdom
Primary
Secondary
Concomitant
Pneumonia Hospitalization 3/1/2005 70 Male 179 lb 7/20/2006 Physician South Africa
Primary
Concomitant
Insomnia 1/1/2006 51 Male 230 lb 7/12/2006 Consumer United States
Primary
Concomitant
Vomiting Hospitalization 74 Male 7/21/2006 Other Health Professional Denmark
Primary
Concomitant
Tricuspid Valve Incompetence Other Serious 7/11/2006 66 Female 179 lb 8/4/2006 Physician Germany
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 2/7/2006 70 Male 174 lb 8/4/2006 Physician United States
Primary
Concomitant
Renal Failure Acute Hospitalization 5/8/2006 58 Male 285 lb 8/7/2006 Pharmacist United States
Primary
Concomitant
Rhabdomyolysis Other Serious 6/1/2006 45 Male 276 lb 8/14/2006 Physician United States
Primary
Concomitant
Restrictive Pulmonary Disease Hospitalization 3/27/2006 72 Male 198 lb 8/14/2006 Physician Germany
Primary
Concomitant
Neoplasm Progression Life Threatening 6/2/2006 Male 8/23/2006
Primary
Concomitant
Renal Failure Life Threatening 1/23/2006 71 Male 187 lb 8/24/2006 Physician Germany
Primary
Concomitant
Lactic Acidosis Hospitalization 77 Male 8/23/2006 United Kingdom
Primary
Concomitant
Neoplasm Progression Life Threatening 6/2/2006 Male 8/30/2006
Primary
Secondary
Concomitant
Cardiac Arrest Death 6/16/2006 57 Male 9/18/2006 Physician Germany
Primary
Concomitant
Cerebral Infarction Hospitalization 2/22/2006 73 Female 192 lb 9/22/2006
Primary
Concomitant
Tumour Invasion Life Threatening 6/2/2006 Male 9/25/2006
Primary
Concomitant
Hepatitis Cholestatic Hospitalization 7/16/2006 53 Male 187 lb 10/12/2006 France
Primary
Concomitant
Cerebral Infarction Hospitalization 2/22/2006 73 Female 192 lb 11/14/2006
Primary
Concomitant
Eructation Other Serious 10/4/2006 74 Female 180 lb 11/15/2006 Physician United States
Primary
Concomitant
Bladder Cancer Other Serious 11/1/2006 Female 182 lb 11/20/2006 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 6/8/2006 78 Female 187 lb 11/13/2006 Physician United Kingdom
Primary
Concomitant
Surgical Procedure Repeated Other Serious 10/22/2006 66 Male 183 lb 11/22/2006 Physician France
Primary
Concomitant
Pulmonary Tuberculosis Hospitalization 6/1/2006 Male 160 lb 12/13/2006 Other Health Professional United States
Primary
Concomitant
Ureteral Neoplasm Other Serious 11/1/2006 Female 182 lb 12/18/2006 Physician United States
Primary
Concomitant
Thrombosis Hospitalization 1/1/2006 49 Female 198 lb 1/19/2007 Other Health Professional Germany
Primary
Secondary
Concomitant
Sepsis Hospitalization 8/31/2006 57 Male 300 lb 2/9/2007 Physician United States
Primary
Concomitant
Nausea Other Serious 7/1/2006 76 Male 195 lb 11/28/2006 United States
Primary
Concomitant
Respiratory Failure Hospitalization 11/2/2006 58 Male 268 lb 3/29/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Low Density Lipoprotein Decreased Other Serious 62 Male 11/28/2006 United States
Primary
Concomitant
Head Titubation 12/31/2006 53 Male 261 lb 5/17/2007 Physician United States
Primary
Concomitant
Lichenoid Keratosis Other Serious 7/1/2006 76 Female 152 lb 6/11/2007 Other Health Professional United Kingdom
Primary
Concomitant
Hepatic Enzyme Increased Other Serious 5/29/2007 37 Male 292 lb 6/18/2007 Pharmacist United States
Primary
Concomitant
Jaundice Hospitalization Male 7/3/2007 Physician France
Primary
Secondary
Concomitant
Skin Necrosis Hospitalization 6/1/2007 63 Male 8/6/2007 Other Health Professional France
Primary
Secondary
Concomitant
Peritoneal Haemorrhage Hospitalization 7/24/2007 66 Male 9/4/2007 Other Health Professional France
Primary
Secondary
Concomitant
Nervous System Disorder Other Serious 6/10/2007 Male 201 lb 9/7/2007 Physician United States
Primary
Secondary
Concomitant
Skin Necrosis Hospitalization 6/1/2007 63 Male 9/10/2007 Other Health Professional France
Primary
Secondary
Concomitant
Skin Necrosis Hospitalization 6/1/2007 63 Male 9/12/2007 Other Health Professional France
Primary
Secondary
Concomitant
Lower Limb Fracture Hospitalization 6/2/2007 64 Male 200 lb 9/20/2007 Consumer United States
Primary
Concomitant
Peritoneal Haemorrhage Hospitalization 7/24/2007 Male 9/21/2007 Other Health Professional France
Primary
Secondary
Concomitant
Pain Other Serious 1/1/2007 Female 192 lb 9/24/2007 Consumer United States
Primary
Concomitant
Skin Burning Sensation 3/20/2007 30 Male 209 lb 8/16/2007 Other Health Professional United States
Primary
Concomitant
Renal Failure Acute Hospitalization 8/25/2007 66 Male 10/1/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Toxic Shock Syndrome Life Threatening 7/15/2007 67 Male 10/17/2007 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Toxic Shock Syndrome Life Threatening 7/15/2007 67 Male 10/17/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pancreatic Disorder Hospitalization 7/1/2007 Female 10/24/2007 Physician Czech Republic
Primary
Concomitant
Tremor Hospitalization 10/1/2007 66 Male 1/11/2008 Pharmacist United States
Primary
Concomitant
Muscular Weakness Other Serious 52 Female 258 lb 1/18/2008 Other Health Professional Canada
Primary
Concomitant
Urine Output Decreased Other Serious 11/13/2004 84 Male 165 lb 1/19/2008 United Kingdom
Primary
Concomitant
Muscular Weakness Other Serious 52 Female 258 lb 1/25/2008 Other Health Professional Canada
Primary
Concomitant
Tremor Hospitalization 10/1/2007 66 Male 2/7/2008 Pharmacist United States
Primary
Concomitant
Vaginal Haemorrhage Hospitalization 7/1/2007 56 Female 203 lb 2/29/2008 Consumer Germany
Primary
Concomitant
Peripheral Vascular Disorder Other Serious 3/1/2008 Male 265 lb 3/24/2008 Consumer United States
Primary
Concomitant
Hepatitis Hospitalization 6/1/2006 49 Female 5/22/2008 Physician New Zealand
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Hospitalization 7/8/2007 74 Female 6/11/2008 Other Health Professional France
Primary
Secondary
Concomitant
Gingival Bleeding Other Serious 2/14/2008 Female 155 lb 6/20/2008 Physician United States
Primary
Concomitant
Platelet Count Decreased Other Serious 73 Male 7/1/2008 Consumer France
Primary
Concomitant
Interacting
Syncope Life Threatening 6/1/2008 66 Male 7/2/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 5/1/2008 70 Male 7/7/2008 Physician France
Primary
Secondary
Concomitant
Pain Hospitalization 7/13/2007 77 Female 7/3/2008 Physician Belgium
Primary
Concomitant
Cerebrovascular Accident Other Serious 5/19/2008 Male 308 lb 7/10/2008 Consumer United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 2/7/2006 Male 174 lb 7/14/2008 United States
Primary
Concomitant
Vertigo Hospitalization 1/1/2008 Male 7/8/2008 Consumer United States
Primary
Concomitant
Syncope Other Serious 9/1/2007 Female 7/16/2008 Physician United States
Primary
Concomitant
Somnolence 4/1/2007 66 Female 7/24/2008 Consumer United States
Primary
Concomitant
Vision Blurred Life Threatening 6/14/2008 72 Male 130 lb 8/12/2008 United States
Primary
Concomitant
Renal Failure Acute Other Serious 5/1/2008 70 Male 8/20/2008 Physician France
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 7/22/2008 Male 8/21/2008 Canada
Primary
Concomitant
Palpitations Other Serious 1/1/2008 63 Female 297 lb 8/22/2008 United States
Primary
Concomitant
Pain In Extremity Other Serious 8/1/2008 67 Female 230 lb 9/8/2008 United States
Primary
Concomitant
Renal Failure Acute Other Serious 5/1/2008 70 Male 9/9/2008 Physician France
Primary
Secondary
Concomitant
Post Procedural Swelling Other Serious 5/28/2008 59 Male 196 lb 9/2/2008 United States
Primary
Concomitant
Weight Decreased Hospitalization 1/1/2008 Female 291 lb 9/3/2008 Consumer United States
Primary
Concomitant
Pancreatitis Necrotising Hospitalization 8/7/2008 Male 172 lb 9/8/2008 Physician United States
Primary
Concomitant
Weight Decreased Hospitalization 1/1/2008 Female 291 lb 9/11/2008 Consumer United States
Primary
Concomitant
Peritoneal Haemorrhage Hospitalization 7/23/2007 66 Male 9/17/2008 Physician France
Primary
Secondary
Concomitant

Drug Data