Allopurinol combined with Metformin Hydrochloride

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Exostosis Hospitalization 7/14/2002 Female 1/4/2006 France
Primary
Concomitant
Syncope Other Serious 65 Male 4/28/2006 United Kingdom
Primary
Secondary
Concomitant
Urinary Tract Infection Required Intervention 3/16/2006 74 Male 5/9/2006 Other Health Professional United States
Primary
Concomitant
Dyspnoea Other Serious 3/6/2006 75 Male 335 lb 5/12/2006 Consumer United States
Primary
Concomitant
Epilepsy Hospitalization 5/14/2006 45 Male 6/28/2006 Consumer United States
Primary
Secondary
Concomitant
Dyspnoea Other Serious 3/6/2006 75 Male 335 lb 7/6/2006 Consumer United States
Primary
Concomitant
Renal Failure Life Threatening 4/16/2006 70 Male 7/11/2006 Other Health Professional France
Primary
Secondary
Concomitant
Lethargy Hospitalization 5/5/2006 70 Male 7/5/2006 Pharmacist United States
Primary
Secondary
Concomitant
Rash Hospitalization 5/29/2006 81 Male 243 lb 7/14/2006 Pharmacist United States
Primary
Concomitant
Prothrombin Time Prolonged Life Threatening 3/8/2006 73 Male 5/24/2006 Japan
Primary
Concomitant
White Blood Cell Count Increased Life Threatening 3/8/2006 73 Male 7/11/2006 Japan
Primary
Concomitant
Prothrombin Time Prolonged Life Threatening 3/8/2006 73 Male 7/18/2006 Japan
Primary
Concomitant
White Blood Cell Count Increased Death 2/16/2006 70 Female 7/27/2006 Physician Japan
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 74 Male 8/17/2006 Consumer France
Primary
Concomitant
Renal Failure Acute Hospitalization 6/19/2006 77 Male 8/23/2006 Other Health Professional France
Primary
Concomitant
Sepsis Other Serious 9/15/2006 75 Male 172 lb 10/26/2006 Physician Germany
Primary
Concomitant
Sleep Apnoea Syndrome Hospitalization 8/17/2006 Female 3/9/2007 Physician United States
Primary
Concomitant
Cardiac Arrest Life Threatening 1/31/2007 73 Female 198 lb 3/21/2007
Primary
Concomitant
Vomiting Hospitalization 1/1/2005 80 Female 4/5/2007 Other Health Professional Sweden
Primary
Secondary
Concomitant
Cellulitis Hospitalization 9/4/2006 45 Female 4/16/2007 Consumer Australia
Primary
Secondary
Tremor Other Serious 3/1/2007 64 Male 263 lb 4/26/2007 United States
Primary
Concomitant
Loss Of Consciousness Other Serious Female 7/3/2007 Consumer Norway
Primary
Concomitant
Red Blood Cell Sedimentation Rate Increased Other Serious 5/1/2007 Female 7/5/2007 Physician Austria
Primary
Concomitant
Red Blood Cell Sedimentation Rate Increased Other Serious 5/1/2007 Female 7/10/2007 Physician Austria
Primary
Concomitant
Septic Shock Hospitalization Male 7/25/2007 Other Health Professional France
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 6/29/2004 68 Female 8/10/2007 Australia
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 6/29/2004 68 Female 8/11/2007 Australia
Primary
Secondary
Concomitant
Respiratory Disorder Hospitalization 6/17/2007 79 Male 8/28/2007 Physician France
Primary
Secondary
Concomitant
Viral Infection Other Serious 6/1/2007 Male 9/7/2007 Other Health Professional France
Primary
Secondary
Concomitant
Interacting
Skin Necrosis Hospitalization 6/1/2007 63 Male 9/10/2007 Other Health Professional France
Primary
Secondary
Concomitant
Viral Infection Other Serious 6/1/2007 Male 9/19/2007 Other Health Professional France
Primary
Secondary
Concomitant
Interacting
Rhabdomyolysis Hospitalization 3/9/2007 77 Female 282 lb 10/24/2007 Other Health Professional Australia
Primary
Secondary
Concomitant
Cholangitis Other Serious 11/8/2007 Other Health Professional United States
Primary
Concomitant
Blood Glucose Increased Other Serious 10/1/2007 Female 138 lb 11/20/2007 Consumer United States
Primary
Concomitant
Meningitis Death 11/10/2006 66 Female 11/20/2007 Physician Germany
Primary
Secondary
Concomitant
Cholangitis Other Serious 12/1/2007 Other Health Professional United States
Primary
Concomitant
Hyperuricaemia Hospitalization 5/10/2007 63 Male 192 lb 12/3/2007 Japan
Primary
Secondary
Concomitant
Hyperuricaemia Hospitalization 5/10/2007 63 Male 192 lb 12/12/2007 Japan
Primary
Secondary
Concomitant
Red Blood Cell Sedimentation Rate Increased Other Serious 5/1/2007 Female 194 lb 12/28/2007 Physician Austria
Primary
Concomitant
Renal Failure Disability 1/23/2008 61 Male 2/21/2008 Consumer Japan
Primary
Secondary
Concomitant
Ventricular Fibrillation Death 8/24/2005 Male 5/13/2008 Czech Republic
Primary
Concomitant
Feeling Drunk Hospitalization 6/2/2008 Female 6/27/2008 Pharmacist Netherlands
Primary
Concomitant
Weight Decreased Hospitalization 8/28/2008 55 Female 220 lb 10/10/2008 Physician United States
Primary
Concomitant
Weight Decreased Hospitalization 8/28/2008 55 Female 220 lb 10/10/2008 Physician United States
Primary
Concomitant
Vomiting Hospitalization 8/5/2008 71 Male 223 lb 10/3/2008 Physician Canada
Primary
Secondary
Concomitant
Swollen Tongue Life Threatening 9/30/2008 72 Male 10/17/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Myalgia Other Serious 5/1/2008 Male 247 lb 10/17/2008 Physician United States
Primary
Concomitant
Pancreatitis Necrotising Hospitalization 8/7/2008 Male 172 lb 10/14/2008 Physician United States
Primary
Concomitant
Tooth Abscess Life Threatening 9/30/2008 72 Male 10/20/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Swollen Tongue Life Threatening 9/30/2008 72 Male 10/24/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Scotoma Other Serious 7/1/2008 Male 10/27/2008 Pharmacist Canada
Primary
Concomitant
Renal Failure Other Serious 4/16/2006 Male 10/22/2008 Denmark
Primary
Concomitant
Rhabdomyolysis Hospitalization 7/21/2007 86 Male 11/3/2008 Other Health Professional Australia
Primary
Concomitant
Herpes Virus Infection Other Serious 9/29/2008 Male 11/11/2008 Physician United States
Primary
Secondary
Concomitant
Viral Myositis Hospitalization 5/15/2008 64 Male 12/1/2008 Other Health Professional Australia
Primary
Secondary
Concomitant
Viral Myositis Hospitalization 5/15/2008 64 Male 12/3/2008 Other Health Professional Australia
Primary
Secondary
Concomitant
Weight Increased Male 348 lb 1/12/2009 Physician United States
Primary
Secondary
Concomitant
Drug Abuse Death 48 Male 1/28/2009 Other Health Professional United States
Primary
Secondary
Thrombosis Hospitalization 12/30/2008 2/13/2009 Other Health Professional Netherlands
Primary
Concomitant
Septic Shock Hospitalization 5/8/2008 Male 121 lb 2/16/2009 Physician Japan
Primary
Secondary
Concomitant
Flushing Male 2/24/2009 United States
Primary
Secondary
Concomitant
Vasodilatation 12/26/2008 61 Male 2/20/2009 Japan
Primary
Secondary
Concomitant
Death Death 48 Male 3/26/2009 Other Health Professional United States
Primary
Secondary
Thrombocytopenia Hospitalization 12/15/2008 88 Female 4/9/2009 Other Health Professional France
Primary
Secondary
Concomitant
Blood Creatine Phosphokinase Increased Hospitalization 10/17/2007 74 Female 5/1/2009 Physician Japan
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Required Intervention 65 Male 4/30/2009 Malaysia
Primary
Concomitant
Product Substitution Issue Other Serious 1/1/2009 61 Female 3/25/2009 Pharmacist United States
Primary
Concomitant
Peripheral Embolism Hospitalization Male 5/20/2009 Physician Netherlands
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 12/15/2008 88 Female 5/22/2009 Other Health Professional France
Primary
Secondary
Concomitant
Pain In Extremity Other Serious 4/5/2009 81 Male 179 lb 6/2/2009 Other Health Professional United States
Primary
Concomitant
Trigger Finger 1/1/2008 Male 229 lb 6/11/2009 United States
Primary
Concomitant
Pain In Extremity 2/1/2009 Male 240 lb 6/12/2009 United States
Primary
Concomitant
Pneumonia Staphylococcal Death 12/1/2008 82 Female 6/12/2009 United States
Primary
Concomitant
Headache Hospitalization 2/25/2009 58 Male 6/15/2009 Physician Italy
Primary
Concomitant
Rhabdomyolysis Life Threatening 4/25/2009 65 Female 139 lb 7/10/2009 Other Health Professional Denmark
Primary
Concomitant
Cerebrovascular Accident Hospitalization 10/24/2007 57 Male 215 lb 7/10/2009 Other Health Professional United States
Primary
Concomitant
Vertigo Other Serious 5/5/2009 Male 7/14/2009 Pharmacist Australia
Primary
Concomitant
Respiratory Failure Hospitalization 4/1/2009 Female 8/6/2009 Physician United States
Primary
Concomitant
Varices Oesophageal Hospitalization 11/23/2007 64 Male 364 lb 9/18/2009 United States
Primary
Concomitant
Treatment Noncompliance Hospitalization 54 Male 281 lb 9/22/2009 United States
Primary
Concomitant
Hiccups 8/24/2009 73 Male 216 lb 10/1/2009 Consumer United States
Primary
Concomitant
Vomiting Hospitalization 62 Male 267 lb 9/25/2009 United States
Primary
Concomitant
Weight Increased Hospitalization 7/1/2007 48 Male 456 lb 9/23/2009 United States
Primary
Concomitant
Vitamin D Deficiency Hospitalization 72 Female 9/23/2009 United States
Primary
Concomitant
Weight Increased Hospitalization 50 Male 354 lb 9/22/2009 United States
Primary
Concomitant
Rhabdomyolysis Other Serious 8/20/2009 50 Male 163 lb 10/14/2009 Other Health Professional United Kingdom
Primary
Concomitant
Pain Hospitalization 1/1/2009 75 Male 12/15/2009 Physician Belgium
Primary
Concomitant
Cytolytic Hepatitis Life Threatening 8/1/2009 59 Male 12/17/2009 Physician Belgium
Primary
Concomitant
Respiratory Failure Hospitalization 9/22/2009 77 Male 154 lb 12/21/2009 Physician United States
Primary
Concomitant
Respiratory Failure Hospitalization 9/22/2009 77 Male 154 lb 12/31/2009 Physician United States
Primary
Concomitant
Respiratory Failure Hospitalization 9/22/2009 77 Male 154 lb 1/5/2010 Physician United States
Primary
Concomitant
Product Quality Issue 3/17/2009 68 Male 1/4/2010 Consumer United States
Primary
Concomitant
Weight Decreased Hospitalization 12/1/2008 Male 462 lb 1/12/2010 Physician United States
Primary
Concomitant
Syncope Other Serious 1/1/2009 Male 183 lb 1/22/2010 Pharmacist United States
Primary
Concomitant
Interacting
Urinary Tract Obstruction Hospitalization 76 Male 1/22/2010 United States
Primary
Concomitant
Vomiting Hospitalization 7/12/2009 82 Female 2/4/2010 Pharmacist Germany
Primary
Concomitant
Treatment Noncompliance Hospitalization 72 Male 256 lb 2/5/2010 United States
Primary
Concomitant
Waist Circumference Increased Hospitalization 72 Male 256 lb 2/5/2010 United States
Primary
Concomitant
Rib Fracture Hospitalization 7/18/2007 76 Female 238 lb 3/2/2010 Physician United Kingdom
Primary
Concomitant
Haemoglobin Decreased Life Threatening 10/13/2009 Female 3/2/2010 Physician Hungary
Primary
Secondary
Concomitant
Treatment Noncompliance Other Serious 11/16/2009 Male 3/3/2010 Consumer Brazil
Primary
Concomitant
Coronary Artery Bypass Hospitalization Female 127 lb 3/3/2010 Consumer United States
Primary
Concomitant
Adverse Drug Reaction Death 3/4/2010 Physician United States
Primary
Secondary
Malaise Other Serious 10/6/2009 Male 302 lb 3/4/2010 Physician United States
Primary
Concomitant
Staphylococcal Bacteraemia Other Serious 66 Male 3/11/2010 Other Health Professional Portugal
Primary
Secondary
Concomitant
Product Substitution Issue Other Serious 1/1/2010 62 Male 216 lb 3/10/2010 United States
Primary
Concomitant
Yellow Skin Death 11/1/2009 Male 3/17/2010 Consumer United States
Primary
Concomitant
Renal Tubular Necrosis Other Serious 12/1/2007 Male 200 lb 3/17/2010 Consumer United States
Primary
Concomitant
Sepsis Life Threatening 1/1/2007 Male 3/17/2010 Physician United States
Primary
Concomitant
Vision Blurred Other Serious 1/1/2005 Male 3/19/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Pruritus Other Serious 3/12/2010 Male 3/26/2010 United States
Primary
Concomitant
Grand Mal Convulsion Other Serious 1/4/2010 Male 231 lb 3/26/2010 Consumer United Kingdom
Primary
Concomitant
Flatulence 12/1/2009 Male 3/29/2010 Consumer
Primary
Concomitant
Vomiting Hospitalization Male 209 lb 4/30/2010 Pharmacist United States
Primary
Concomitant
Polycythaemia Other Serious 5/19/2009 68 Male 5/10/2010 Other Health Professional Greece
Primary
Concomitant
Myocardial Ischaemia Hospitalization Male 257 lb 5/10/2010 Other Health Professional United States
Primary
Concomitant
Hospitalisation Hospitalization 1/1/2009 71 Female 5/11/2010 Canada
Primary
Concomitant
Vision Blurred Other Serious 1/1/2005 44 Male 5/12/2010 United States
Primary
Secondary
Concomitant
Loss Of Consciousness Hospitalization 4/20/2010 68 Male 240 lb 5/13/2010 United States
Primary
Concomitant
Vomiting Other Serious 4/8/2008 68 Male 5/14/2010 Lawyer United States
Primary
Concomitant
Rhabdomyolysis Hospitalization 5/11/2010 58 Male 240 lb 5/13/2010 Other Health Professional United States
Primary
Concomitant
Myocardial Ischaemia Hospitalization 66 Male 257 lb 5/19/2010 Other Health Professional United States
Primary
Concomitant
Nausea Other Serious 12/1/2008 64 Male 5/21/2010 Consumer United States
Primary
Secondary
Concomitant
Rash Life Threatening 5/3/2010 59 Male 5/24/2010 Physician Japan
Primary
Concomitant
Liver Injury Hospitalization 1/13/2010 54 Male 183 lb 5/27/2010 Physician Germany
Primary
Secondary
Concomitant
Staphylococcal Infection Hospitalization 4/17/2010 77 Female 5/27/2010 Other Health Professional France
Primary
Concomitant
Liver Injury Other Serious 1/13/2010 54 Male 183 lb 5/27/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Liver Injury Hospitalization 1/13/2010 Male 183 lb 5/26/2010 Physician Germany
Primary
Secondary
Gait Disturbance Hospitalization 10/1/2007 74 Female 6/7/2010 Physician Japan
Primary
Concomitant
Pulse Absent Other Serious 4/19/2010 69 Female 6/10/2010 United States
Primary
Secondary
Urine Abnormality Other Serious 3/10/2010 85 Male 6/22/2010 Consumer United States
Primary
Secondary
Concomitant
Rash Life Threatening 5/3/2010 59 Male 6/23/2010 Physician Japan
Primary
Concomitant
Drug Dose Omission Male 7/31/2010 Consumer United States
Primary
Concomitant
Tachycardia Hospitalization 5/22/2010 65 Female 7/30/2010 Other Health Professional Denmark
Primary
Concomitant
Fluid Retention 9/1/2009 60 Male 190 lb 9/14/2010 Consumer United States
Primary
Concomitant
Muscular Weakness Other Serious 5/2/2010 87 Male 209 lb 9/14/2010 Consumer United States
Primary
Concomitant
Renal Failure Hospitalization 9/29/2010 11/23/2010 Physician Belgium
Primary
Concomitant
Rhabdomyolysis Hospitalization 3/9/2007 77 Female 282 lb 12/3/2010 Other Health Professional Australia
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 10/11/2010 79 Female 12/14/2010 Other Health Professional France
Primary
Secondary
Metabolic Acidosis Life Threatening 11/19/2010 72 Female 12/17/2010 Physician Denmark
Primary
Concomitant
H1n1 Influenza Hospitalization 12/9/2010 75 Male 130 lb 1/7/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Hypokalaemia Hospitalization 6/12/2010 56 Male 141 lb 1/7/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Cerebrovascular Accident Hospitalization 57 Male 215 lb 1/20/2011 Consumer United States
Primary
Concomitant
Pancreatitis Other Serious 60 1/20/2011 Other Health Professional Denmark
Primary
Secondary
Concomitant
Pancreatitis Acute Other Serious 51 2/10/2011 Pharmacist
Primary
Secondary
Concomitant
Cytolytic Hepatitis Other Serious 1/6/2011 76 Male 2/28/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Neutropenic Colitis Hospitalization 3/4/2010 69 Male 211 lb 2/25/2011 Physician United States
Primary
Concomitant
Movement Disorder Other Serious Male 3/25/2011 Consumer Brazil
Primary
Concomitant
Drug Interaction Other Serious 83 Female 5/2/2011 Other Health Professional Hungary
Primary
Concomitant
Interacting
Conjunctivitis 9/30/2010 59 Male 5/3/2011 Physician United States
Primary
Concomitant

Drug Data