Allopurinol combined with Mesna

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Vomiting Other Serious 12/8/2005 72 Male 152 lb 1/17/2006 Consumer United States
Primary
Secondary
Concomitant
Vomiting Other Serious 12/8/2005 72 Male 152 lb 3/2/2006 Consumer United States
Primary
Secondary
Concomitant
Wrong Drug Administered Death 8/26/2005 21 Male 3/1/2006 Physician United States
Primary
Concomitant
Unresponsive To Verbal Stimuli Other Serious 1/25/2006 85 Female 161 lb 3/16/2006 Consumer United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 2/1/2006 46 Male 170 lb 3/31/2006 Consumer United States
Primary
Concomitant
Respiratory Distress Life Threatening 4/3/2006 Male 207 lb 4/5/2006 Other Health Professional United States
Primary
Concomitant
Cystitis Haemorrhagic Hospitalization 4/27/2005 61 Male 4/18/2006 Consumer United States
Primary
Concomitant
Renal Failure Acute Other Serious 2/1/2006 46 Male 170 lb 4/27/2006 Consumer United States
Primary
Concomitant
Nightmare Hospitalization 12/24/2005 77 Male 185 lb 5/31/2006 Other Health Professional Australia
Primary
Secondary
Concomitant
Tachycardia Hospitalization 3/4/2006 Male 311 lb 8/11/2006 United States
Primary
Secondary
Staphylococcal Infection Hospitalization 4/9/2007 19 Male 164 lb 5/9/2007 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Life Threatening 4/9/2007 19 Male 164 lb 5/24/2007 Physician United States
Primary
Secondary
Concomitant
Ventricular Tachycardia Life Threatening 4/9/2007 19 Male 167 lb 6/4/2007 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Life Threatening 4/9/2007 19 Male 167 lb 6/7/2007 Physician United States
Primary
Secondary
Concomitant
Nephrogenic Fibrosing Dermopathy Death 15 Male 77 lb 6/27/2007 Consumer United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 9 Male 7/10/2007 Other Health Professional Sweden
Primary
Concomitant
Febrile Neutropenia Hospitalization 7/4/2007 Male 168 lb 7/13/2007 Consumer Australia
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 9 Male 8/3/2007 Other Health Professional Sweden
Primary
Concomitant
Neutropenia Life Threatening 6/19/2007 Female 110 lb 8/17/2007 Physician Germany
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 21 Female 9/5/2007 Other Health Professional United States
Primary
Secondary
Toxic Epidermal Necrolysis Required Intervention 10 Male 9/17/2007 Other Health Professional Sweden
Primary
Secondary
Concomitant
Nephrogenic Systemic Fibrosis Death 1/1/2004 15 Male 77 lb 9/26/2007 Consumer United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 21 Female 8/16/2007 Physician United States
Primary
Secondary
Sepsis Neonatal Hospitalization Male 8/16/2007 Physician United States
Primary
Secondary
White Blood Cell Count Decreased Hospitalization 10 Male 11/8/2007 Sweden
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 10 Male 12/14/2007 Sweden
Primary
Secondary
Concomitant
Vomiting Other Serious 12/17/2007 69 Male 1/23/2008 Consumer United States
Primary
Secondary
Concomitant
Ventricular Fibrillation Death 1/1/2008 Male 4/10/2008 Other Health Professional France
Primary
Secondary
Concomitant
Meningeal Disorder Hospitalization 7/4/2007 Male 168 lb 4/14/2008 Consumer Australia
Primary
Secondary
Concomitant
Nephrogenic Systemic Fibrosis Other Serious 1/1/2004 15 Male 77 lb 4/29/2008 Lawyer United States
Primary
Secondary
Concomitant
Nephrogenic Systemic Fibrosis Other Serious 1/1/2004 15 Male 77 lb 5/5/2008 Lawyer United States
Primary
Secondary
Concomitant
Nephrogenic Systemic Fibrosis Other Serious 1/1/2004 5/6/2008 Other Health Professional Germany
Primary
Secondary
Concomitant
Epstein-barr Virus Infection Life Threatening 3/27/2008 53 Female 121 lb 5/8/2008 Other Health Professional Italy
Primary
Concomitant
Xerosis Other Serious 1/1/2000 11 Male 77 lb 6/19/2008 Lawyer United States
Primary
Secondary
Concomitant
Xerosis Other Serious 1/1/2000 11 Male 77 lb 6/23/2008 Lawyer United States
Primary
Secondary
Concomitant
Pancreatitis Acute Hospitalization 5/14/2008 Male 7/23/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Nephrogenic Systemic Fibrosis Other Serious 1/1/2004 8/19/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Nephrogenic Systemic Fibrosis Other Serious 1/1/2004 8/22/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Ventricular Tachycardia Required Intervention 4/12/2007 19 Male 165 lb 10/10/2008 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Required Intervention 4/12/2007 19 Male 165 lb 11/18/2008 Physician United States
Primary
Secondary
Concomitant
Xerosis Other Serious 1/1/2000 11 Male 77 lb 12/3/2008 United States
Primary
Secondary
Concomitant
Xerosis Other Serious 1/1/2000 11 Male 77 lb 12/3/2008 United States
Primary
Secondary
Concomitant
Pharyngeal Oedema Hospitalization 12/27/2008 Male 183 lb 12/30/2008 United States
Primary
Secondary
Clostridium Difficile Colitis 22 Female 2/19/2009 Other Health Professional United States
Primary
Concomitant
Virus Serology Test Positive Death 4/17/2009 58 Female 97 lb 6/2/2009 Physician Japan
Primary
Concomitant
Virus Serology Test Positive Death 4/17/2009 58 Female 97 lb 7/10/2009 Physician Japan
Primary
Concomitant
Wound Other Serious 1/1/2004 8/3/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Febrile Neutropenia Life Threatening 9/17/2009 Male 10/5/2009 Other Health Professional Philippines
Primary
Concomitant
Thrombocytopenia Hospitalization 10/5/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Herpes Virus Infection Hospitalization 10/17/2009 Male 1/4/2010 Physician Italy
Primary
Secondary
Concomitant
Stomatitis Hospitalization 9/22/2009 Male 1/4/2010 Physician Italy
Primary
Secondary
Concomitant
Ventricular Tachycardia Required Intervention 4/12/2007 19 Male 165 lb 3/2/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Varicella Other Serious Male 3/10/2010 Other Health Professional United States
Primary
Concomitant
Wound Infection Other Serious Male 3/15/2010 Other Health Professional United States
Primary
Concomitant
Arrhythmia Death 3/10/2010 56 Female 128 lb 3/26/2010 Physician Germany
Primary
Concomitant
Arrhythmia Death 3/10/2010 56 Female 128 lb 4/9/2010 Physician Germany
Primary
Concomitant
Encephalopathy Hospitalization 4/1/2010 70 Female 101 lb 4/16/2010 Consumer United States
Primary
Secondary
Concomitant
Wound Infection Other Serious Male 4/20/2010 Other Health Professional United States
Primary
Concomitant
Encephalopathy Hospitalization 4/1/2010 70 Female 101 lb 4/22/2010 Consumer United States
Primary
Secondary
Concomitant
Syncope Other Serious 10/6/2007 50 Male 194 lb 6/30/2010 Lawyer United States
Primary
Concomitant
Febrile Neutropenia Other Serious 6/25/2010 48 Male 7/6/2010 Pharmacist United States
Primary
Concomitant
Pyrexia Other Serious 1/9/2009 58 Female 97 lb 7/28/2010 Physician Japan
Primary
Concomitant
Tachycardia Other Serious 9/20/2007 50 Male 194 lb 8/27/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Respiratory Tract Infection Hospitalization 2/25/2009 78 Male 9/10/2010 Pharmacist Germany
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 9/17/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Malaise Other Serious 1/1/2010 40 Male 181 lb 12/2/2010 Pharmacist Canada
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 1/29/2010 49 Male 110 lb 12/13/2010 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 1/29/2010 49 Male 110 lb 12/13/2010 Physician Japan
Primary
Concomitant
Headache Other Serious 9/1/2007 50 Male 194 lb 1/12/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Hospitalization 12/15/2010 44 Female 2/16/2011 Other Health Professional France
Primary
Secondary
Concomitant
Hepatosplenomegaly Death 1/27/2011 68 Male 2/15/2011 Other Health Professional United States
Primary
Concomitant
Nausea Other Serious 28 Female 3/17/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Drug Exposure During Pregnancy Hospitalization 28 Female 3/22/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Febrile Neutropenia Other Serious 10/1/2001 28 Female 4/5/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Premature Baby Death 3/28/2011 United States
Primary
Secondary
Concomitant
Nausea Other Serious 28 Female 4/21/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Drug Exposure Before Pregnancy Congenital Anomaly 28 Female 3/28/2011 United States
Primary
Secondary
Concomitant
Petechiae Other Serious 1/29/2010 49 Male 110 lb 5/20/2011 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 3/2/2011 45 Female 6/3/2011 Consumer United Kingdom
Primary
Secondary
Concomitant
Acute Respiratory Distress Syndrome Death 6/13/2011 71 Male 211 lb 6/30/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 3/2/2011 45 Female 7/5/2011 Physician Spain
Primary
Secondary
Concomitant
Diabetes Insipidus Hospitalization 3/21/2011 49 Male 6/28/2011 Other Health Professional United States
Primary
Concomitant
Pulseless Electrical Activity Death 1/25/2011 66 Male 6/30/2011 Other Health Professional United States
Primary
Concomitant
Bacterial Sepsis Death 5/18/2004 51 Male 163 lb 7/25/2011 Physician Japan
Primary
Secondary
Concomitant
Vasculitis Other Serious 6/1/2011 83 Female 8/4/2011 Other Health Professional France
Primary
Secondary
Concomitant
Purpura Hospitalization 6/1/2011 83 Female 8/10/2011 Other Health Professional France
Primary
Secondary
Concomitant
Cardiac Failure Death 6/13/2011 71 Male 211 lb 8/19/2011 Consumer United States
Primary
Secondary
Concomitant
Renal Failure Hospitalization 6/13/2011 71 Male 211 lb 8/22/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Mucosal Inflammation Disability Female 120 lb 9/12/2011 Pharmacist Brazil
Primary
Concomitant
Bradycardia Life Threatening 1/25/2011 66 Male 9/8/2011 Pharmacist United States
Primary
Concomitant
Haematuria Other Serious 1/1/2011 21 Female 119 lb 9/23/2011 Pharmacist Brazil
Primary
Concomitant
Myocardial Fibrosis Disability 1/1/2000 11 Male 77 lb 9/27/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Lung Consolidation Other Serious 1/19/2011 3 Male 35 lb 9/27/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Death 1/24/2011 3 Male 33 lb 9/29/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Methylobacterium Infection Other Serious 5/22/2011 8 Female 49 lb 9/30/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Periorbital Oedema Life Threatening 1/27/2011 6 Female 40 lb 10/3/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Cytomegalovirus Infection Life Threatening 1/19/2011 3 Male 35 lb 10/3/2011 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Deep Vein Thrombosis Death 12/7/2010 6 Female 40 lb 10/4/2011 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Pulmonary Hypertension Other Serious 1/1/2011 8 Female 49 lb 10/6/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Death 1/24/2011 3 Male 35 lb 10/4/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Methylobacterium Infection Other Serious 8 Female 49 lb 10/6/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Febrile Neutropenia Life Threatening 6 Female 40 lb 10/6/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Death 1/24/2011 3 Male 33 lb 10/18/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pulmonary Hypertension Other Serious 1/1/2011 8 Female 49 lb 10/21/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Death 1/24/2011 3 Male 35 lb 10/18/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Blood Glucose Increased Other Serious 2/11/2011 55 Female 123 lb 11/11/2011 Physician Japan
Primary
Concomitant
Staphylococcal Bacteraemia Death 11/22/2010 15 Female 95 lb 12/12/2011 Physician Japan
Primary
Concomitant
Liver Disorder Other Serious 1/1/2011 8 Female 49 lb 12/29/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Infection Hospitalization 1/29/2009 3 Female 35 lb 2/10/2012 Physician Japan
Primary
Concomitant
Septic Shock Hospitalization 9/28/2011 66 Male 2/28/2012 Other Health Professional Italy
Primary
Secondary
Concomitant
Liver Function Test Abnormal Life Threatening 1/30/2012 3 Female 31 lb 3/5/2012 Physician Poland
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 4/1/2011 33 Female 3/7/2012 Physician Czech Republic
Primary
Secondary
Concomitant
Mucosal Inflammation Other Serious 1/31/2011 66 Male 3/14/2012 Other Health Professional United States
Primary
Concomitant
Rash Erythematous Other Serious 2/16/2012 61 Female 148 lb 4/5/2012 Physician France
Primary
Concomitant
Lung Infection Hospitalization 12/5/2011 60 Male 4/23/2012 Other Health Professional Italy
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 12/5/2011 60 Male 4/26/2012 Physician Italy
Primary
Secondary
Concomitant
Bone Marrow Failure Hospitalization 12/5/2011 60 Male 4/27/2012 Italy
Primary
Secondary
Concomitant
Pneumonia Hospitalization 12/5/2011 60 Male 5/1/2012 Physician Italy
Primary
Secondary
Concomitant
Staphylococcal Sepsis Death 2/10/2012 50 Male 5/25/2012 Other Health Professional Italy
Primary
Secondary
Concomitant
Febrile Neutropenia Death 2/10/2012 50 Male 5/31/2012 Pharmacist Italy
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 12/5/2011 60 Male 5/31/2012 Physician Italy
Primary
Secondary
Concomitant
Cytomegalovirus Infection Hospitalization 1/26/2012 61 Female 137 lb 6/4/2012 Other Health Professional France
Primary
Secondary
Concomitant
Staphylococcal Sepsis Death 2/11/2011 55 Female 123 lb 6/8/2012 Physician Japan
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 2/10/2012 50 Male 6/15/2012 Other Health Professional Italy
Primary
Secondary
Concomitant
Haemolytic Uraemic Syndrome Death 1/29/2009 3 Female 35 lb 7/5/2012 Physician Japan
Primary
Concomitant
Hyperglycaemia Hospitalization 4/10/2012 Female 7/11/2012 Physician Germany
Primary
Secondary
Concomitant
Hypokalaemia Hospitalization 4/10/2012 Female 7/12/2012 Physician Germany
Primary
Secondary
Concomitant
Graft Versus Host Disease In Skin Death 2/11/2011 55 Female 123 lb 7/31/2012 Physician Japan
Primary
Secondary
Concomitant
Pleural Effusion Other Serious 3/29/2012 70 Female 194 lb 8/1/2012 Physician United States
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 3/29/2012 70 Female 194 lb 8/16/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Venoocclusive Disease Other Serious 2011 8 Female 49 lb 10/29/2013 Pharmacist Gb
Primary
Secondary
Concomitant
Venoocclusive Disease Death 8 Female 49 lb 6/27/2013 Other Health Professional Gb
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Life Threatening 2/11/2011 55 Female 123 lb 9/6/2012 Physician Jp
Primary
Secondary
Concomitant
Toxicity To Various Agents Other Serious 8 Female 49 lb 10/22/2013 Other Health Professional Gb
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 12/21/2011 70 Female 198 lb 10/11/2012 Physician Us
Primary
Secondary
Concomitant
Thrombocytopenia Death 9/12/2012 82 Female 148 lb 5/17/2013 Physician De
Primary
Secondary
Concomitant
Stomatitis Life Threatening 1/25/2011 14 Male 95 lb 3/14/2013 Physician Jp
Primary
Secondary
Concomitant
Constipation Hospitalization 2/2013 79 Female 140 lb 4/29/2013 Physician De
Primary
Secondary
Constipation Hospitalization 2/2013 79 Female 142 lb 5/7/2013 Physician De
Primary
Secondary
Concomitant
Off Label Use Death NotSpecified 6/24/2013 Physician Us
Primary
Secondary
Concomitant
Off Label Use Other Serious NotSpecified 6/25/2013 Physician Us
Primary
Secondary
Concomitant
Ventriculo-peritoneal Shunt Other Serious NotSpecified 7/9/2013 Physician Us
Primary
Secondary
Concomitant
Wrong Technique In Drug Usage Process Other Serious NotSpecified 6/26/2013 Physician Us
Primary
Secondary
Concomitant
Wrong Technique In Drug Usage Process Other Serious NotSpecified 6/26/2013 Physician Us
Primary
Secondary
Concomitant
Wrong Technique In Drug Usage Process Other Serious NotSpecified 6/26/2013 Physician Us
Primary
Secondary
Concomitant
Wrong Technique In Drug Usage Process Other Serious NotSpecified 6/26/2013 Physician Us
Primary
Secondary
Concomitant
Seroma Hospitalization 8/6/2013 Male 9/12/2013 Physician De
Primary
Secondary
Concomitant
Haemorrhage Intracranial Death 6/6/2013 33 Female 180 lb 10/3/2013 Physician Us
Primary
Secondary
Concomitant
Platelet Count Decreased Hospitalization 10/7/2012 55 Male 152 lb 10/23/2013 Physician It
Primary
Secondary
Concomitant
Pulmonary Embolism Life Threatening 10/15/2013 Male 11/11/2013 Physician De
Primary
Secondary
Concomitant

Drug Data