Allopurinol combined with Marcumar

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Coombs Positive Haemolytic Anaemia Other Serious 9/5/2005 Male 176 lb 1/5/2006 Physician Germany
Primary
Concomitant
Somnolence Life Threatening 11/5/2005 68 Female 249 lb 1/3/2006 Germany
Primary
Concomitant
Coombs Positive Haemolytic Anaemia Other Serious 9/5/2005 Male 176 lb 1/9/2006 Physician Germany
Primary
Concomitant
Renal Failure Life Threatening 1/23/2006 Male 192 lb 3/24/2006 Physician Germany
Primary
Concomitant
Syncope Hospitalization 2/10/2006 75 Male 192 lb 4/4/2006 Physician Germany
Primary
Concomitant
Venous Thrombosis Limb Hospitalization 11/1/2005 Female 4/11/2006 Consumer
Primary
Concomitant
Cystitis Haemorrhagic Hospitalization 4/27/2005 61 Male 4/18/2006 Consumer United States
Primary
Concomitant
Venous Thrombosis Limb Hospitalization 11/1/2005 Female 4/20/2006 Consumer
Primary
Concomitant
Venous Thrombosis Limb Hospitalization 11/1/2005 Female 4/25/2006 Consumer
Primary
Concomitant
Venous Thrombosis Limb Hospitalization 11/1/2005 Female 5/1/2006 Consumer
Primary
Concomitant
Wound Hospitalization 11/1/2005 Female 5/2/2006 Consumer
Primary
Concomitant
Major Depression Hospitalization 9/1/2005 63 Male 5/9/2006 Physician Germany
Primary
Concomitant
Vomiting Hospitalization 1/23/2006 67 Male 163 lb 5/22/2006 Physician Germany
Primary
Concomitant
Visual Field Defect Other Serious 4/1/2006 Male 176 lb 7/17/2006 Physician Germany
Primary
Concomitant
Renal Failure Life Threatening 1/23/2006 71 Male 187 lb 8/24/2006 Physician Germany
Primary
Concomitant
Septic Shock Other Serious 3/28/2006 73 Male 165 lb 9/1/2006 Physician Germany
Primary
Concomitant
Cardiac Arrest Death 6/16/2006 57 Male 9/18/2006 Physician Germany
Primary
Concomitant
Sudden Death Death 6/16/2006 57 Male 179 lb 10/5/2006 Physician Germany
Primary
Concomitant
Paresis Hospitalization 6/7/2006 67 Male 176 lb 10/10/2006 Physician Germany
Primary
Concomitant
Paraparesis Other Serious 6/7/2006 67 Male 176 lb 10/25/2006 Physician Germany
Primary
Concomitant
Somnolence Other Serious 6/7/2006 67 Male 176 lb 10/27/2006 Physician Germany
Primary
Concomitant
Sepsis Other Serious 6/7/2006 67 Male 176 lb 10/31/2006 Physician Germany
Primary
Concomitant
Treatment Noncompliance Life Threatening 1/23/2006 71 Male 187 lb 11/1/2006 Physician Germany
Primary
Concomitant
Tooth Malformation Hospitalization 10/23/2006 Male 194 lb 11/3/2006 Physician United Kingdom
Primary
Concomitant
Tooth Malformation Hospitalization 10/23/2006 Male 194 lb 11/8/2006 Physician United Kingdom
Primary
Concomitant
Right Ventricular Failure Life Threatening 10/6/2006 83 Female 11/8/2006 Germany
Primary
Concomitant
Renal Failure Chronic Hospitalization 9/5/2006 72 Female 12/20/2006 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Traumatic Brain Injury Death 80 Male 187 lb 12/15/2006 Physician Germany
Primary
Concomitant
Non-hodgkin's Lymphoma Other Serious 4/18/2006 61 Male 12/18/2006 Germany
Primary
Concomitant
Ventricular Tachycardia Other Serious 11/1/2006 Male 175 lb 3/2/2007 Physician Belgium
Primary
Concomitant
Orthopnoea Hospitalization 1/1/2007 62 Male 159 lb 3/7/2007 Physician Switzerland
Primary
Concomitant
Periodontal Disease Hospitalization 1/30/2007 Male 159 lb 3/15/2007 Physician United Kingdom
Primary
Concomitant
Muscle Twitching Hospitalization 1/1/2007 Female 5/23/2007 Physician Germany
Primary
Concomitant
Renal Failure Other Serious 8/14/2005 78 Male 194 lb 6/4/2007 Physician Germany
Primary
Concomitant
Vomiting Other Serious 1/1/2007 79 Female 7/14/2007 Switzerland
Primary
Concomitant
Periodontal Disease Hospitalization 1/30/2007 67 Male 159 lb 8/24/2007 Physician United Kingdom
Primary
Concomitant
Tooth Disorder Hospitalization 10/23/2006 66 Male 194 lb 8/24/2007 Physician United Kingdom
Primary
Concomitant
Orthopnoea Hospitalization 1/1/2007 62 Male 159 lb 8/31/2007 Physician Switzerland
Primary
Concomitant
Weight Decreased Other Serious 68 Male 9/26/2007 Physician Germany
Primary
Concomitant
Visual Acuity Reduced Other Serious 1/1/2007 Male 9/26/2007 Consumer Germany
Primary
Concomitant
Tachycardia Other Serious 74 Male 10/16/2007 Consumer Germany
Primary
Concomitant
Weight Increased Hospitalization Female 11/18/2007 Physician Germany
Primary
Concomitant
Tachycardia Other Serious 74 Male 11/30/2007 Physician Germany
Primary
Concomitant
Pyrexia Hospitalization 1/1/2007 Female 174 lb 12/21/2007 Other Health Professional Germany
Primary
Concomitant
Urinary Tract Infection Other Serious 69 Female 154 lb 12/27/2007 Physician Germany
Primary
Secondary
Concomitant
Death Other Serious 9/1/2005 Male 1/7/2008 Physician Germany
Primary
Concomitant
Renal Failure Acute Hospitalization 6/17/2007 73 Male 1/25/2008 Physician Switzerland
Primary
Concomitant
Interacting
Stevens-johnson Syndrome Hospitalization 8/4/2003 Female 1/25/2008 Physician Germany
Primary
Secondary
Concomitant
Pyrexia Hospitalization 1/1/2007 Female 174 lb 1/31/2008 Other Health Professional Germany
Primary
Concomitant
Toxic Epidermal Necrolysis Life Threatening 1/31/2005 69 Male 2/13/2008 Physician Germany
Primary
Secondary
Concomitant
Gait Disturbance Hospitalization 11/1/2007 Male 2/13/2008 Physician Germany
Primary
Concomitant
Rheumatoid Arthritis Hospitalization 1/1/2007 Female 174 lb 2/14/2008 Other Health Professional Germany
Primary
Concomitant
Agranulocytosis Hospitalization 8/31/2007 Male 2/25/2008 Other Health Professional Germany
Primary
Secondary
Concomitant
Gait Disturbance Hospitalization 11/1/2007 Male 2/26/2008 Physician Germany
Primary
Concomitant
Weight Decreased Other Serious 68 Male 2/28/2008 Physician Germany
Primary
Concomitant
Gait Disturbance Hospitalization 11/1/2007 Male 3/11/2008 Physician Germany
Primary
Concomitant
Stevens-johnson Syndrome Hospitalization 8/4/2003 68 Female 3/4/2008 Other Health Professional Germany
Primary
Secondary
Concomitant
Gait Disturbance Hospitalization 11/1/2007 Male 3/21/2008 Germany
Primary
Concomitant
Extrasystoles Hospitalization 2/7/2008 85 Female 148 lb 4/2/2008 Other Health Professional Switzerland
Primary
Concomitant
Interacting
Renal Function Test Abnormal Life Threatening Male 196 lb 7/15/2008 Pharmacist Germany
Primary
Concomitant
Transaminases Increased Other Serious 10/9/2007 Female 104 lb 7/24/2008 Physician Germany
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 1/1/2008 77 Female 176 lb 7/28/2008 Physician Germany
Primary
Concomitant
Gingivitis Hospitalization 1/30/2007 67 Male 159 lb 8/18/2008 Physician Germany
Primary
Concomitant
Tooth Extraction Hospitalization 10/23/2006 66 Male 194 lb 8/18/2008 Physician Germany
Primary
Concomitant
Prothrombin Time Prolonged Other Serious 8/1/2008 Male 10/27/2008 Physician Germany
Primary
Concomitant
Interacting
Prothrombin Time Shortened Other Serious 8/1/2008 Female 231 lb 10/30/2008 Physician Germany
Primary
Concomitant
Prothrombin Time Shortened Other Serious 8/1/2008 Female 231 lb 11/28/2008 Physician Germany
Primary
Concomitant
Thrombocytopenia Other Serious 8/19/2008 Female 11/30/2008 Consumer Germany
Primary
Concomitant
Thrombocytopenia Other Serious 8/19/2008 Female 12/10/2008 Consumer Germany
Primary
Concomitant
Stevens-johnson Syndrome Hospitalization 6/16/2006 Female 12/16/2008 Physician Germany
Primary
Secondary
Concomitant
Stevens-johnson Syndrome Hospitalization 6/16/2006 Female 12/18/2008 Physician Germany
Primary
Secondary
Concomitant
Prothrombin Time Prolonged Life Threatening 12/2/2008 72 Female 190 lb 12/22/2008 Other Health Professional Germany
Primary
Concomitant
Anaemia Hospitalization 5/15/2008 1/15/2009 Other Health Professional Germany
Primary
Concomitant
Thrombocytopenia Other Serious 8/19/2008 Female 1/20/2009 Consumer Germany
Primary
Concomitant
Thrombocytopenia Other Serious 8/19/2008 Female 2/6/2009 Consumer Germany
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 8/19/2008 Female 2/25/2009 Consumer Germany
Primary
Secondary
Concomitant
Optic Atrophy Hospitalization 6/3/2008 59 Male 3/18/2009 Physician Germany
Primary
Concomitant
Vomiting Other Serious 1/1/2008 72 Male 190 lb 3/23/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Haemorrhage Hospitalization 10/27/2008 72 Male 258 lb 3/31/2009 Other Health Professional Germany
Primary
Secondary
Interacting
Drug Administration Error Hospitalization 10/10/2008 4/17/2009 Consumer Germany
Primary
Concomitant
Anaemia Hospitalization 5/15/2008 5/7/2009 Other Health Professional Germany
Primary
Concomitant
Laboratory Test Abnormal Hospitalization 2/16/2009 81 Male 220 lb 7/9/2009 Germany
Primary
Concomitant
Oesophagitis Other Serious Male 7/17/2009 Consumer Germany
Primary
Concomitant
Haemoglobin Decreased Other Serious 6/20/2007 91 Female 179 lb 7/30/2009 Physician Germany
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 8/19/2008 Female 148 lb 8/3/2009 Physician Germany
Primary
Concomitant
Right Ventricular Failure Hospitalization 2/5/2009 Female 8/10/2009 Physician Germany
Primary
Concomitant
Thrombocytopenia Hospitalization 8/19/2008 Female 148 lb 8/12/2009 Physician Germany
Primary
Secondary
Concomitant
Oesophagitis Other Serious Male 8/18/2009 Physician Germany
Primary
Concomitant
Vertigo Other Serious 72 Female 8/19/2009 Physician Germany
Primary
Secondary
Arrhythmia Hospitalization 8/2/2009 77 8/25/2009 Physician Germany
Primary
Concomitant
Sick Sinus Syndrome Hospitalization 7/25/2009 77 9/15/2009 Physician Germany
Primary
Concomitant
International Normalised Ratio Increased Other Serious 6/20/2007 91 Female 179 lb 9/18/2009 Physician Germany
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 1/1/2008 79 9/22/2009 Physician Germany
Primary
Secondary
Concomitant
Vertigo Other Serious 72 Female 9/25/2009 Physician Germany
Primary
Secondary
Vertigo Other Serious 72 Female 9/25/2009 Physician Germany
Primary
Secondary
Platelet Function Test Abnormal Hospitalization 1/1/2008 79 Male 11/12/2009 Physician Germany
Primary
Concomitant
Pallor Hospitalization 10/27/2008 72 Male 11/25/2009 Physician Germany
Primary
Secondary
Right Ventricular Failure Hospitalization 2/5/2009 Female 12/11/2009 Physician Germany
Primary
Concomitant
Prothrombin Time Abnormal Hospitalization 2/1/2008 80 Male 220 lb 1/8/2010 Germany
Primary
Concomitant
Sudden Cardiac Death Death 1/18/2010 75 Male 176 lb 3/1/2010 Physician Germany
Primary
Concomitant
Muscle Spasms Life Threatening 12/1/2009 70 Male 192 lb 2/23/2010 Germany
Primary
Concomitant
Sudden Cardiac Death Death 1/18/2010 75 Male 176 lb 3/5/2010 Physician Germany
Primary
Concomitant
Sudden Cardiac Death Death 1/18/2010 75 Male 176 lb 3/5/2010 Physician Germany
Primary
Concomitant
Stevens-johnson Syndrome Other Serious 6/1/2006 65 Female 3/19/2010 Physician Germany
Primary
Secondary
Diarrhoea Other Serious 1/1/2010 Male 3/26/2010 Physician Germany
Primary
Concomitant
Myocardial Infarction Other Serious 3/7/2010 53 Male 3/31/2010 Physician Germany
Primary
Concomitant
Urinary Tract Infection Other Serious 1/1/2008 79 Male 4/5/2010 Germany
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 12/1/2009 72 Male 4/9/2010 Consumer Germany
Primary
Concomitant
Peripheral Arterial Occlusive Disease Other Serious 5/26/2009 65 Male 172 lb 4/12/2010 Physician Germany
Primary
Secondary
Concomitant
Dermatitis Exfoliative Hospitalization Male 178 lb 4/23/2010 Physician Austria
Primary
Concomitant
Platelet Function Test Abnormal Hospitalization 1/1/2008 79 Male 4/30/2010 Physician Germany
Primary
Concomitant
Prothrombin Time Abnormal Hospitalization 1/1/2010 Female 5/3/2010 Physician Germany
Primary
Concomitant
Interacting
Tachycardia Hospitalization 4/13/2010 78 Male 5/6/2010 Physician Germany
Primary
Concomitant
Right Ventricular Failure Hospitalization 2/5/2009 61 Female 5/10/2010 Physician Germany
Primary
Concomitant
Syncope Hospitalization 4/10/2010 78 Male 5/18/2010 Physician Germany
Primary
Concomitant
Serositis Other Serious 2/4/2010 71 Male 172 lb 5/18/2010 Physician Germany
Primary
Concomitant
Femoral Artery Occlusion Hospitalization 5/26/2009 65 Male 172 lb 6/8/2010 Physician Germany
Primary
Secondary
Concomitant
Microcytic Anaemia 70 Male 6/3/2010 Germany
Primary
Concomitant
Somnolence Hospitalization 9/18/2008 83 Male 6/18/2010 Physician Germany
Primary
Secondary
Sick Sinus Syndrome Hospitalization 8/2/2009 77 Female 6/23/2010 Physician Germany
Primary
Concomitant
Tachycardia Death 5/1/2010 49 Female 276 lb 6/25/2010 Physician Switzerland
Primary
Concomitant
Stevens-johnson Syndrome Hospitalization 7/7/2008 79 Female 6/30/2010 Other Health Professional Germany
Primary
Secondary
Skin Burning Sensation Other Serious 4/1/2010 74 7/1/2010 Pharmacist Germany
Primary
Concomitant
Meningioma Hospitalization 3/28/2010 67 Male 220 lb 7/1/2010 Physician Germany
Primary
Concomitant
Drug Ineffective Other Serious Female 139 lb 7/6/2010 Pharmacist Germany
Primary
Secondary
Concomitant
Proctitis Haemorrhagic Hospitalization 2/26/2010 80 Female 143 lb 7/2/2010 Physician Germany
Primary
Secondary
Concomitant
Blood Creatinine Increased Other Serious 6/17/2010 71 Male 176 lb 7/13/2010 Physician Germany
Primary
Concomitant
Meningioma Hospitalization 3/28/2010 67 Male 220 lb 7/13/2010 Physician Germany
Primary
Concomitant
Microcytic Anaemia Life Threatening 1/1/2009 70 Male 192 lb 7/22/2010 Germany
Primary
Concomitant
Rash Maculo-papular Hospitalization 6/26/2010 70 Female 8/3/2010 Physician Germany
Primary
Concomitant
Hypoglycaemia Life Threatening 1/12/2010 71 Male 170 lb 8/9/2010 Physician Germany
Primary
Concomitant
Proctitis Haemorrhagic Hospitalization 2/26/2010 80 Female 143 lb 8/6/2010 Physician Germany
Primary
Secondary
Concomitant
Ventricular Hypokinesia Hospitalization 2/26/2010 80 Female 143 lb 8/19/2010 Physician Germany
Primary
Secondary
Concomitant
Sudden Cardiac Death Hospitalization 1/3/2010 77 Male 8/30/2010 Physician Germany
Primary
Concomitant
Muscle Spasms Life Threatening 1/1/2009 70 Male 192 lb 8/27/2010 Physician Germany
Primary
Concomitant
Subarachnoid Haemorrhage Other Serious 7/20/2010 50 Male 8/31/2010 Other Health Professional Germany
Primary
Concomitant
Muscle Spasms Life Threatening 1/1/2009 70 Male 192 lb 9/1/2010 Physician Germany
Primary
Concomitant
Tinnitus Other Serious 5/8/2010 56 Female 243 lb 9/10/2010 Physician Switzerland
Primary
Concomitant
Pyrexia Hospitalization 8/18/2010 77 Male 183 lb 9/10/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Tinnitus Other Serious 5/8/2010 56 Female 243 lb 9/16/2010 Physician Switzerland
Primary
Concomitant
Withdrawal Syndrome Other Serious 5/1/2010 81 Female 183 lb 9/21/2010 Physician Germany
Primary
Concomitant
Subarachnoid Haemorrhage Other Serious 7/20/2010 50 Male 9/20/2010 Other Health Professional Germany
Primary
Concomitant
Varicose Vein Other Serious 1/1/2009 69 Female 198 lb 9/27/2010 Physician Germany
Primary
Secondary
Concomitant
Pyrexia Hospitalization 8/18/2010 77 Male 183 lb 10/1/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Varicose Vein Other Serious 1/1/2009 69 Female 207 lb 10/7/2010 Physician Germany
Primary
Secondary
Concomitant
Withdrawal Syndrome Other Serious 5/1/2010 81 Female 183 lb 10/17/2010 Physician Germany
Primary
Concomitant
Food Aversion Disability 6/26/2010 78 Female 154 lb 10/25/2010 Pharmacist Germany
Primary
Secondary
Concomitant
Food Aversion Disability 6/26/2010 78 Female 154 lb 10/27/2010 Pharmacist Germany
Primary
Secondary
Concomitant
Myocardial Infarction Other Serious 4/27/2010 71 Female 163 lb 10/28/2010 Physician Germany
Primary
Concomitant
Presyncope Hospitalization 8/17/2010 71 Male 231 lb 10/29/2010 Physician Germany
Primary
Concomitant

Drug Data