Allopurinol combined with Loxonin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Gastric Ulcer Haemorrhage Hospitalization 5/27/2005 48 Female 12/30/2005 Physician Japan
Primary
Concomitant
Stress Hospitalization 5/1/2005 48 Female 91 lb 2/2/2006 Physician Japan
Primary
Secondary
Concomitant
Stress Hospitalization 5/1/2005 48 Female 91 lb 3/10/2006 Physician Japan
Primary
Secondary
Concomitant
Motor Dysfunction Other Serious 4/29/2006 59 Male 121 lb 6/14/2006 Physician Japan
Primary
Secondary
Concomitant
Haemodialysis Hospitalization 7/9/2006 72 Female 7/24/2006 Physician Japan
Primary
Concomitant
Hallucination Hospitalization 7/9/2006 72 Female 8/4/2006 Physician Japan
Primary
Concomitant
White Blood Cell Count Increased Other Serious 7/14/2006 Male 8/10/2006 Pharmacist Japan
Primary
Concomitant
Hallucination Hospitalization 7/9/2006 72 Female 8/11/2006 Physician Japan
Primary
Concomitant
Liver Disorder Hospitalization 7/6/2006 82 Female 86 lb 10/9/2006 Physician Japan
Primary
Concomitant
Liver Disorder Hospitalization 7/6/2006 82 Female 86 lb 10/18/2006 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 7/6/2006 82 Female 86 lb 10/26/2006 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Increased 5/29/2006 Male 10/31/2006 Pharmacist Japan
Primary
Concomitant
Drug Eruption Hospitalization 3/1/2006 75 Male 10/31/2006 Physician Japan
Primary
Secondary
Concomitant
Rash Papular Other Serious 3/1/2006 Male 141 lb 11/8/2006 Physician Japan
Primary
Secondary
Concomitant
Rash Papular Hospitalization 3/1/2006 Male 141 lb 11/16/2006 Physician Japan
Primary
Secondary
Concomitant
Viral Infection Hospitalization 8/31/2006 Female 82 lb 11/20/2006 Physician Japan
Primary
Secondary
Concomitant
Drug Eruption Other Serious 3/1/2006 Male 141 lb 11/28/2006 Physician Japan
Primary
Secondary
Concomitant
Viral Infection Hospitalization 8/31/2006 Female 82 lb 12/1/2006 Physician Japan
Primary
Secondary
Concomitant
Drug Eruption Other Serious 3/1/2006 Male 141 lb 12/6/2006 Physician Japan
Primary
Secondary
Concomitant
Drug Eruption Other Serious 3/1/2006 Male 141 lb 12/7/2006 Physician Japan
Primary
Secondary
Concomitant
Viral Infection Hospitalization 8/31/2006 Female 82 lb 12/18/2006 Physician Japan
Primary
Secondary
Concomitant
Vomiting Other Serious 11/3/2006 69 Male 366 lb 12/19/2006 Pharmacist Japan
Primary
Secondary
Concomitant
Wheezing Death 11/17/2006 57 Male 143 lb 12/22/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Systemic Inflammatory Response Syndrome Hospitalization 11/3/2006 57 Male 143 lb 1/2/2007 Other Health Professional Japan
Primary
Secondary
Concomitant
Red Blood Cell Count Decreased Other Serious 1/22/2007 86 Female 3/2/2007 Physician Japan
Primary
Concomitant
Toxic Induced Encephalopathy Hospitalization 3/23/2007 84 Female 5/3/2007 Physician Japan
Primary
Concomitant
Urine Colour Abnormal Hospitalization 3/19/2007 60 Female 154 lb 5/6/2007 Physician Japan
Primary
Secondary
Concomitant
Liver Disorder Hospitalization 44 Male 5/9/2007 Physician Japan
Primary
Concomitant
Red Blood Cell Count Decreased Other Serious 1/22/2007 86 Female 6/25/2007 Physician Japan
Primary
Concomitant
Toxic Encephalopathy Hospitalization 3/23/2007 84 Female 7/5/2007 Physician Japan
Primary
Concomitant
Hepatocellular Damage Other Serious 3/13/2007 52 Male 8/7/2007 Physician Japan
Primary
Secondary
Concomitant
Hepatocellular Damage Other Serious 3/13/2007 Male 8/10/2007 Pharmacist Japan
Primary
Secondary
Concomitant
Myalgia Other Serious 3/13/2007 52 Male 8/14/2007 Physician Japan
Primary
Secondary
Concomitant
Anaemia Hospitalization 78 Female 8/16/2007 Pharmacist Japan
Primary
Concomitant
Hepatocellular Damage Other Serious 3/13/2007 Male 8/16/2007 Pharmacist Japan
Primary
Secondary
Concomitant
Hepatocellular Damage Other Serious 3/13/2007 52 Male 8/21/2007 Physician Japan
Primary
Secondary
Concomitant
Restlessness Disability 7/31/2007 83 Female 8/21/2007 Physician Japan
Primary
Concomitant
Hepatocellular Damage Other Serious 3/13/2007 Male 8/22/2007 Pharmacist Japan
Primary
Secondary
Concomitant
Upper Gastrointestinal Haemorrhage Life Threatening 8/12/2007 86 Male 220 lb 9/7/2007 Pharmacist Japan
Primary
Secondary
Concomitant
Urticaria Hospitalization 2/25/2007 Female 9/12/2007 Physician Japan
Primary
Secondary
Concomitant
Subdural Haematoma Evacuation Other Serious 1/6/2007 61 Male 146 lb 11/1/2007 Physician Japan
Primary
Concomitant
Supraventricular Tachycardia Hospitalization 9/26/2007 Female 11/7/2007 Physician Japan
Primary
Secondary
Concomitant
Interacting
Wound Complication Hospitalization 10/5/2007 65 Male 112 lb 11/8/2007 Physician Japan
Primary
Concomitant
Cholestasis Hospitalization 3/16/2008 Male 119 lb 4/14/2008 Physician Japan
Primary
Secondary
Concomitant
Pneumonia Hospitalization 11/17/2007 46 Male 143 lb 4/16/2008 Consumer United States
Primary
Secondary
Concomitant
Pneumonia Hospitalization 11/17/2007 Male 143 lb 4/14/2008 Physician Japan
Primary
Secondary
Concomitant
Cholestasis Hospitalization 3/16/2008 Male 119 lb 5/9/2008 Physician Japan
Primary
Secondary
Concomitant
Oedema Peripheral Life Threatening 3/31/2008 85 Female 5/19/2008 Physician Japan
Primary
Concomitant
Post Procedural Haemorrhage Life Threatening 3/31/2008 85 Female 95 lb 5/27/2008 Physician Japan
Primary
Concomitant
Road Traffic Accident Life Threatening 4/18/2007 53 Male 6/10/2008 Physician Japan
Primary
Concomitant
Vertebral Artery Occlusion Hospitalization 5/28/2008 Female 86 lb 6/18/2008 Physician Japan
Primary
Concomitant
Hepatic Function Abnormal Hospitalization 6/3/2008 77 Male 146 lb 6/20/2008 Physician Japan
Primary
Concomitant
Cardiac Failure Other Serious 5/23/2008 44 Male 6/20/2008 Other Health Professional Japan
Primary
Concomitant
Flatulence Other Serious 75 Female 6/25/2008 Pharmacist Japan
Primary
Secondary
Jaundice Other Serious 5/14/2008 Male 144 lb 6/30/2008 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 11/7/2007 Male 143 lb 6/27/2008 Physician Japan
Primary
Secondary
Concomitant
Flatulence Other Serious 75 Female 7/2/2008 Pharmacist Japan
Primary
Secondary
Platelet Count Decreased Other Serious 5/14/2008 68 7/8/2008 Physician Japan
Primary
Secondary
Concomitant
Platelet Count Decreased Other Serious 5/14/2008 68 Male 7/10/2008 Physician Japan
Primary
Secondary
Concomitant
Jaundice Other Serious 5/14/2008 Male 144 lb 7/15/2008 Physician Japan
Primary
Secondary
Concomitant
Ventricular Fibrillation Death 5/23/2008 Male 121 lb 7/18/2008 Other Health Professional Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 6/27/2008 81 Male 7/21/2008 Pharmacist Japan
Primary
Concomitant
Therapeutic Response Decreased Other Serious 12/7/2006 42 Female 7/23/2008 Physician Japan
Primary
Concomitant
Troponin T Hospitalization 7/2/2008 Male 163 lb 7/24/2008 Physician Japan
Primary
Concomitant
Neutropenia Hospitalization 7/18/2008 77 Female 7/29/2008 Pharmacist Japan
Primary
Concomitant
Troponin T Hospitalization 7/2/2008 Male 163 lb 7/29/2008 Physician Japan
Primary
Concomitant
Rhabdomyolysis Other Serious 12/8/2008 12/24/2008 Physician Japan
Primary
Concomitant
Rhabdomyolysis Other Serious 12/8/2008 12/30/2008 Japan
Primary
Concomitant
Melaena Other Serious 1/18/2009 2/9/2009 Japan
Primary
Concomitant
Melaena Other Serious 1/18/2009 2/25/2009 Japan
Primary
Concomitant
Rhabdomyolysis Other Serious 4/1/2007 3/13/2009 Japan
Primary
Concomitant
Lung Infection Hospitalization 7/27/2009 68 10/28/2009 Physician Japan
Primary
Secondary
Concomitant
Ventricular Tachycardia Hospitalization 4/18/2009 Male 198 lb 12/9/2009 Physician Japan
Primary
Concomitant
Neutrophil Count Decreased Other Serious 11/21/2008 77 Female 12/4/2009 Physician Japan
Primary
Secondary
Concomitant
Hypoglycaemia Other Serious 12/16/2009 54 Male 12/30/2009 Japan
Primary
Concomitant
Tumour Lysis Syndrome Hospitalization 1/12/2008 51 Male 1/12/2010 Physician Japan
Primary
Secondary
Concomitant
Lung Infection Hospitalization 7/27/2009 68 Male 132 lb 2/5/2010 Physician Japan
Primary
Secondary
Concomitant
Septic Shock Hospitalization 12/9/2008 Male 2/12/2010 Physician Japan
Primary
Secondary
Concomitant
Pancreatitis Hospitalization 7/7/2009 Male 2/19/2010 Physician Japan
Primary
Concomitant
Renal Disorder Hospitalization 2/1/2010 Male 3/8/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Prostate Cancer Stage Iv Death 12/18/2008 82 Male 137 lb 3/10/2010 Japan
Primary
Concomitant
Renal Disorder Hospitalization 2/1/2010 Male 3/18/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Prostate Cancer Stage Iv Death 12/18/2008 82 Male 137 lb 3/19/2010 Japan
Primary
Concomitant
Vomiting Hospitalization 1/4/2010 Male 119 lb 3/19/2010 Physician Japan
Primary
Secondary
Concomitant
Septic Shock Hospitalization 12/9/2008 Male 132 lb 3/23/2010 Physician Japan
Primary
Secondary
Concomitant
Renal Cell Carcinoma Hospitalization 8/26/2009 50 Male 106 lb 3/22/2010 Physician Japan
Primary
Concomitant
Upper Respiratory Tract Inflammation Hospitalization 1/26/2006 42 Male 82 lb 4/1/2010 Physician Japan
Primary
Secondary
Concomitant
Renal Failure Death 5/28/2008 76 Male 132 lb 4/7/2010 Physician Japan
Primary
Concomitant
Intracranial Tumour Haemorrhage Death 3/5/2008 69 Male 4/8/2010 Other Health Professional Japan
Primary
Concomitant
Lung Infection Hospitalization 7/27/2009 68 Male 132 lb 4/9/2010 Physician Japan
Primary
Secondary
Concomitant
Rash Other Serious 9/16/2009 76 Male 99 lb 4/26/2010 Physician Japan
Primary
Secondary
Concomitant
Pancreatitis Hospitalization 7/7/2009 68 Male 80 lb 4/27/2010 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 6/25/2009 66 Male 119 lb 4/29/2010 Physician Japan
Primary
Concomitant
Malaise Other Serious 4/20/2010 79 Male 158 lb 5/27/2010 Pharmacist Japan
Primary
Concomitant
Malaise Other Serious 4/20/2010 79 Male 158 lb 6/28/2010 Pharmacist Japan
Primary
Concomitant
Subdural Haematoma Other Serious 6/8/2009 82 Female 7/12/2010 Physician Japan
Primary
Secondary
Concomitant
Lung Infection Death Female 161 lb 10/6/2010 Consumer Brazil
Primary
Concomitant
Palpitations Other Serious 3/15/2004 45 Male 139 lb 12/22/2010 Physician Japan
Primary
Concomitant
Death Death 12/1/2010 77 Female 1/12/2011 Pharmacist Japan
Primary
Concomitant
Ileus Other Serious 4/20/2010 79 Male 158 lb 1/21/2011 Pharmacist Japan
Primary
Secondary
Concomitant
Ileus Hospitalization 4/20/2010 79 Male 158 lb 2/3/2011 Physician Japan
Primary
Concomitant
Loss Of Consciousness Hospitalization 1/14/2011 89 Female 3/1/2011 Physician Japan
Primary
Concomitant
Rhabdomyolysis Hospitalization 11/19/2010 76 Male 119 lb 3/8/2011 Physician Japan
Primary
Concomitant
Loss Of Consciousness Hospitalization 1/14/2011 89 Female 66 lb 3/23/2011 Physician Japan
Primary
Concomitant
Rhabdomyolysis Death 11/19/2010 76 Male 119 lb 4/1/2011 Physician Japan
Primary
Concomitant
Myelocyte Count Increased Life Threatening 1/11/2010 63 Male 4/27/2011 Physician Japan
Primary
Concomitant
Pneumonia Influenzal Hospitalization 11/22/2010 67 Male 5/12/2011 Physician Japan
Primary
Secondary
Concomitant
Colitis Ischaemic Life Threatening 3/7/2011 79 Male 165 lb 5/17/2011 Physician Japan
Primary
Concomitant
Mucosal Inflammation Death 3/30/2011 73 Male 120 lb 6/1/2011 Physician Japan
Primary
Secondary
Concomitant
Rectal Perforation Death 3/18/2011 57 Female 6/2/2011 Consumer Japan
Primary
Secondary
Concomitant
Sepsis Life Threatening 9/21/2010 62 Male 104 lb 6/8/2011 Physician Japan
Primary
Secondary
Concomitant
Neutropenia Other Serious 4/1/2011 64 Male 6/9/2011 Physician Japan
Primary
Concomitant
Thrombocytopenia Death 3/30/2011 73 Male 120 lb 6/14/2011 Physician Japan
Primary
Secondary
Concomitant
Rectal Perforation Death 3/18/2011 57 Female 6/16/2011 Consumer Japan
Primary
Secondary
Concomitant
Rectal Perforation Death 3/18/2011 57 Female 6/21/2011 Consumer Japan
Primary
Secondary
Concomitant
Peritonitis Death 3/14/2011 57 Female 6/28/2011 Consumer Japan
Primary
Secondary
Concomitant
Eating Disorder Other Serious 9/1/2010 26 Female 121 lb 7/7/2011 Physician Japan
Primary
Concomitant
Platelet Count Decreased Death 11/22/2010 67 Male 7/12/2011 Physician Japan
Primary
Secondary
Concomitant
Pancytopenia Hospitalization 4/5/2011 79 Female 7/12/2011 Physician Japan
Primary
Secondary
Blood Glucose Increased Other Serious 7/11/2011 74 Male 154 lb 7/14/2011 Physician Japan
Primary
Concomitant
Lipase Increased 12/9/2009 76 Male 7/15/2011 Physician Japan
Primary
Concomitant
Hepatic Function Abnormal Hospitalization 5/1/2011 64 Male 108 lb 7/15/2011 Physician Japan
Primary
Secondary
Concomitant
Retinal Detachment Hospitalization 7/8/2011 68 Male 7/20/2011 Physician Japan
Primary
Secondary
Encephalitis Fungal Death Male 139 lb 8/1/2011 Physician Japan
Primary
Secondary
Concomitant
Pneumonia Hospitalization 4/5/2011 79 Female 8/1/2011 Physician Japan
Primary
Secondary
Fungaemia Death 6/22/2005 46 Male 126 lb 8/2/2011 Physician Japan
Primary
Secondary
Concomitant
Sinusitis Hospitalization 1/28/2010 63 Male 7/27/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Liver Disorder Other Serious 8/12/2010 36 Male 212 lb 8/9/2011 Physician Japan
Primary
Secondary
Concomitant
Pancytopenia Death 4/5/2011 79 Female 8/15/2011 Physician Japan
Primary
Secondary
Hypertension Death 6/25/2009 65 Male 119 lb 8/29/2011 Physician Japan
Primary
Concomitant
Graft Versus Host Disease Disability 6/6/2011 13 Female 88 lb 9/20/2011 Physician Japan
Primary
Concomitant
Somnolence Hospitalization 3/30/2009 59 Male 9/27/2011 Physician Japan
Primary
Concomitant
Retinal Detachment Hospitalization 7/8/2011 68 Male 137 lb 9/27/2011 Physician Japan
Primary
Secondary
Stevens-johnson Syndrome Other Serious 11/19/2010 63 Male 143 lb 9/28/2011 Physician Japan
Primary
Concomitant
Eating Disorder Hospitalization 6/11/2009 66 Female 128 lb 10/7/2011 Physician Japan
Primary
Concomitant
Hyperglycaemia Life Threatening 10/3/2011 Male 10/13/2011 Physician Japan
Primary
Concomitant
Exposed Bone In Jaw Hospitalization 9/21/2010 54 Female 10/14/2011 Other Health Professional Japan
Primary
Concomitant
Pancreatitis Hospitalization 9/21/2011 69 Male 10/17/2011 Other Health Professional Japan
Primary
Concomitant
Death Death 10/3/2011 Male 10/18/2011 Physician Japan
Primary
Concomitant
Stomatitis Hospitalization 6/11/2009 66 Female 128 lb 10/18/2011 Physician Japan
Primary
Concomitant
Ileus Other Serious 4/22/2010 79 Male 158 lb 10/26/2011 Pharmacist Japan
Primary
Concomitant
Ileus Other Serious 4/20/2010 79 Male 158 lb 10/31/2011 Physician Japan
Primary
Concomitant
Metabolic Acidosis Other Serious 10/4/2011 43 Male 11/3/2011 Physician Japan
Primary
Concomitant
Protein Urine Present Hospitalization 4/17/2011 72 Male 11/3/2011 Physician Japan
Primary
Secondary
Concomitant
Myelodysplastic Syndrome Other Serious 8/7/2010 64 Male 143 lb 11/4/2011 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 8/7/2010 64 Male 143 lb 11/4/2011 Physician Japan
Primary
Secondary
Concomitant
Visual Impairment Death 6/6/2011 13 Female 88 lb 11/8/2011 Physician Japan
Primary
Concomitant
Osteonecrosis Of Jaw Hospitalization 9/21/2010 54 Female 11/9/2011 Other Health Professional Japan
Primary
Concomitant
Myelodysplastic Syndrome Hospitalization 8/22/2011 65 Male 121 lb 11/11/2011 Physician Japan
Primary
Secondary
Renal Impairment Other Serious Male 11/24/2011 Physician Japan
Primary
Concomitant

Drug Data