Allopurinol combined with Levofloxacin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Rash Required Intervention 1/4/2006 57 Male 163 lb 1/18/2006 Pharmacist United States
Primary
Concomitant
Pyrexia Other Serious 1/1/2003 38 Female 2/13/2006 Physician Germany
Primary
Secondary
Concomitant
Platelet Count Decreased Hospitalization 10/30/2004 29 Female 121 lb 2/18/2006 Other Health Professional United States
Primary
Concomitant
Somnolence Hospitalization 1/5/2006 84 Male 2/26/2006 Other Health Professional France
Primary
Secondary
Concomitant
Lymphocyte Count Decreased Hospitalization 10/30/2004 29 Female 121 lb 4/1/2006 United States
Primary
Concomitant
Thrombotic Thrombocytopenic Purpura Other Serious 9/8/2005 73 Female 4/20/2006 Physician Japan
Primary
Secondary
Thrombotic Microangiopathy Other Serious 2/22/2003 61 Male 95 lb 5/16/2006 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Life Threatening 1/15/2006 59 Male 6/7/2006 Japan
Primary
Concomitant
Venoocclusive Liver Disease Disability 1/1/2004 61 Female 98 lb 6/7/2006 Physician Japan
Primary
Secondary
Concomitant
Weight Increased Hospitalization 4/13/2006 67 Male 6/29/2006 Physician United States
Primary
Secondary
Concomitant
Leukopenia Other Serious 5/12/2006 62 Female 185 lb 6/29/2006 Physician Germany
Primary
Secondary
Concomitant
Weight Increased Life Threatening 4/1/2005 56 Male 7/6/2006 United States
Primary
Concomitant
Weight Increased Life Threatening 4/1/2005 56 Male 7/11/2006 Other Health Professional United States
Primary
Concomitant
Leukopenia Other Serious 5/12/2006 62 Female 185 lb 7/13/2006 Physician Germany
Primary
Secondary
Concomitant
Nervous System Disorder Other Serious 6/25/2006 52 Male 168 lb 9/8/2006 Physician Japan
Primary
Concomitant
Venoocclusive Liver Disease Life Threatening 9/13/2004 56 Female 190 lb 9/8/2006 United States
Primary
Concomitant
Pulmonary Oedema Life Threatening 12/7/2004 68 Female 199 lb 9/8/2006 Other Health Professional United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Life Threatening 1/15/2006 59 Male 9/19/2006 Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 1/30/2006 59 Male 9/26/2006 Japan
Primary
Secondary
Concomitant
Vomiting Hospitalization 9/29/2006 68 Male 174 lb 10/5/2006 United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 9/9/2004 55 Female 10/20/2006 United States
Primary
Concomitant
Vomiting 2/8/2006 36 Male Physician United States
Primary
Concomitant
Pancreatitis Hospitalization 8/1/2006 76 Female 128 lb 10/25/2006 Other Health Professional Germany
Primary
Concomitant
Renal Failure Life Threatening 1/28/2005 54 Female 106 lb 11/9/2006 Physician Japan
Primary
Concomitant
Thrombocythaemia Hospitalization 10/9/2006 62 Male 11/10/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Retroperitoneal Neoplasm Life Threatening 1/28/2005 54 Female 106 lb 11/20/2006 Physician Japan
Primary
Concomitant
White Blood Cell Count Increased Other Serious 10/1/2006 58 Female 132 lb 12/7/2006 Pharmacist Japan
Primary
Concomitant
White Blood Cell Count Increased Other Serious 10/1/2006 58 Female 132 lb 12/7/2006 Pharmacist Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 12/4/2006 71 Male 1/17/2007 Physician Japan
Primary
Secondary
Concomitant
Oral Mucosal Eruption Other Serious 11/23/2006 44 Male 1/25/2007 Japan
Primary
Secondary
White Blood Cell Count Decreased Other Serious 12/4/2006 71 Male 1/25/2007 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 12/4/2006 71 Male 2/5/2007 Physician Japan
Primary
Secondary
Concomitant
Drug Eruption Other Serious 11/23/2006 44 Male 2/7/2007 Japan
Primary
Secondary
White Blood Cell Count Decreased Other Serious 12/4/2006 71 Male 2/12/2007 Physician Japan
Primary
Secondary
Concomitant
Pco2 Abnormal Other Serious 2/1/2007 Female 250 lb 3/2/2007 Other Health Professional United States
Primary
Concomitant
Nasopharyngitis Other Serious 11/23/2006 45 Male 2/22/2007 Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 12/4/2006 71 Male 2/28/2007 Physician Japan
Primary
Secondary
Concomitant
Nasopharyngitis Other Serious 11/23/2006 45 Male 3/2/2007 Japan
Primary
Secondary
Concomitant
Nephrogenic Fibrosing Dermopathy Other Serious 1/3/2007 69 Female 172 lb 3/13/2007 Physician United States
Primary
Concomitant
Vomiting Hospitalization 12/13/2006 69 Female 84 lb 3/12/2007 Physician Japan
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 10/1/2006 58 Female 132 lb 3/20/2007 Pharmacist Japan
Primary
Concomitant
Torsade De Pointes Other Serious 3/6/2007 45 Male 165 lb 3/19/2007 Other Health Professional United States
Primary
Concomitant
Multi-organ Failure Other Serious 3/2/2007 Male 139 lb 3/30/2007 Physician Japan
Primary
Concomitant
Nephrogenic Fibrosing Dermopathy Other Serious 1/3/2007 69 Female 172 lb 4/25/2007 Consumer United States
Primary
Concomitant
Multi-organ Failure Other Serious 3/2/2007 Male 139 lb 4/25/2007 Physician Japan
Primary
Secondary
Concomitant
Renal Failure Hospitalization 5/7/2007 79 Male 5/24/2007 Other Health Professional Italy
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 12/4/2006 71 Male 5/18/2007 Physician Japan
Primary
Concomitant
Pulmonary Mass Other Serious 12/4/2006 71 Male 5/24/2007 Physician Japan
Primary
Concomitant
Intestinal Adenocarcinoma Death 4/4/2005 56 Male 139 lb 6/5/2007 Physician Japan
Primary
Concomitant
Vomiting Other Serious 12/25/2004 Female 110 lb 6/25/2007 Consumer United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 12/4/2006 71 Male 6/28/2007 Physician Japan
Primary
Concomitant
Toxic Skin Eruption Life Threatening 6/3/2007 88 Female 93 lb 7/10/2007 Physician Japan
Primary
Secondary
Concomitant
Dyspnoea Hospitalization 6/1/2007 Male 163 lb 7/10/2007 United States
Primary
Concomitant
Toxic Skin Eruption Life Threatening 6/3/2007 88 Female 93 lb 7/13/2007 Physician Japan
Primary
Secondary
Concomitant
Stevens-johnson Syndrome Death 4/24/2007 71 Female 6/29/2007 Japan
Primary
Secondary
Concomitant
Nephrogenic Systemic Fibrosis Other Serious 1/3/2007 69 Female 172 lb 8/7/2007 Consumer United States
Primary
Concomitant
Hepatotoxicity Other Serious 38 Female 8/3/2007 Germany
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 12/4/2006 71 Male 106 lb 9/18/2007 Physician Japan
Primary
Concomitant
Pulmonary Alveolar Haemorrhage Hospitalization 55 Male 9/26/2007 Other Health Professional United States
Primary
Concomitant
Hypotension Death 3/20/2007 78 Female 9/24/2007 Pharmacist United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 2/2/2007 56 Male 181 lb 9/27/2007 Physician Japan
Primary
Concomitant
Rash Generalised Life Threatening 9/18/2007 55 Male 10/1/2007 Other Health Professional Italy
Primary
Concomitant
Rash Life Threatening 9/18/2007 55 Male 10/17/2007 Other Health Professional Italy
Primary
Concomitant
Rash Other Serious 2/3/2007 60 Male 132 lb 11/5/2007 Physician Japan
Primary
Concomitant
Weight Increased Hospitalization 10/15/2007 56 Male 11/15/2007 Physician Germany
Primary
Secondary
Concomitant
Weight Increased Other Serious 10/15/2007 56 Male 11/17/2007 Physician Germany
Primary
Secondary
Concomitant
Weight Increased Other Serious 10/15/2007 56 Male 11/21/2007 Physician Germany
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 2/2/2007 56 Male 181 lb 11/15/2007 Physician Japan
Primary
Secondary
Concomitant
Weight Increased Other Serious 10/15/2007 56 Male 11/22/2007 Physician Germany
Primary
Secondary
Concomitant
Weight Increased Other Serious 10/15/2007 56 Male 11/24/2007 Physician Germany
Primary
Secondary
Concomitant
Weight Increased Other Serious 10/15/2007 56 Male 11/29/2007 Physician Germany
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 12/4/2006 71 Male 106 lb 11/22/2007 Physician Japan
Primary
Concomitant
Unresponsive To Stimuli Life Threatening 9/28/2007 21 Female 150 lb 12/3/2007 Physician United States
Primary
Secondary
Concomitant
Ischaemic Stroke Death 10/22/2007 62 Male 139 lb 12/5/2007 Other Health Professional United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 12/8/2006 71 Male 106 lb 12/14/2007 Physician Japan
Primary
Concomitant
Pneumonia Bacterial Other Serious 10/20/2007 57 Male 115 lb 12/31/2007 Physician Japan
Primary
Concomitant
Vomiting Other Serious 12/25/2004 Female 110 lb 1/15/2008 Consumer United States
Primary
Concomitant
Drug Rash With Eosinophilia And Systemic Symptoms 12/14/2007 53 Male 12/19/2007 United States
Primary
Concomitant
Pyrexia Other Serious 12/8/2006 71 Male 106 lb 1/31/2008 Physician Japan
Primary
Concomitant
Ventricular Fibrillation Death 1/15/2008 79 Male 212 lb 2/6/2008 Pharmacist United States
Primary
Secondary
Concomitant
Swollen Tongue Death 11/4/2004 Female 3/14/2008 Germany
Primary
Secondary
Concomitant
Sputum Culture Positive Other Serious 10/20/2007 57 Male 115 lb 3/14/2008 Physician Japan
Primary
Concomitant
Intestinal Perforation Death 3/4/2008 71 Male 4/4/2008 United States
Primary
Secondary
Concomitant
Swollen Tongue Death 11/4/2004 Female 4/18/2008 Germany
Primary
Secondary
Concomitant
Skin Exfoliation Other Serious 3/23/2008 68 Male 4/28/2008 Pharmacist United States
Primary
Secondary
Leukopenia Other Serious 5/12/2006 62 Female 185 lb 4/29/2008 Physician Germany
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 3/4/2008 91 Male 5/15/2008 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 2/27/2007 76 Male 209 lb 5/19/2008 Physician Germany
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 5/11/2008 61 Male 211 lb 5/14/2008 Other Health Professional United States
Primary
Concomitant
White Blood Cell Count Increased Other Serious 3/4/2008 91 Male 6/3/2008 Physician Japan
Primary
Secondary
Concomitant
Wheezing Hospitalization 5/13/2008 61 Male 211 lb 5/23/2008 Physician United States
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 3/16/2008 76 Male 6/4/2008 Physician Germany
Primary
Concomitant
Renal Failure Hospitalization 4/25/2008 50 Male 5/30/2008 France
Primary
Secondary
Concomitant
Tremor Hospitalization 4/23/2008 62 Male 190 lb 6/17/2008 Pharmacist United States
Primary
Concomitant
Renal Failure Hospitalization 4/25/2008 50 Male 5/30/2008 France
Primary
Secondary
Concomitant
Nephropathy Toxic Hospitalization 10/20/2007 35 Female 121 lb 6/22/2008 Pharmacist United States
Primary
Secondary
Concomitant
Nephropathy Toxic Hospitalization 12/7/2007 58 Male 178 lb 6/22/2008 Pharmacist United States
Primary
Secondary
Concomitant
Nephropathy Toxic Hospitalization 12/4/2007 69 Male 183 lb 6/22/2008 Pharmacist United States
Primary
Secondary
Concomitant
Nephropathy Toxic Hospitalization 12/5/2007 43 Male 197 lb 6/22/2008 Pharmacist United States
Primary
Secondary
Concomitant
Tumour Flare Hospitalization 5/13/2008 61 Male 211 lb 6/17/2008 Physician United States
Primary
Concomitant
Tumour Lysis Syndrome Other Serious 5/21/2008 71 Male 101 lb 6/26/2008 Physician Japan
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 10/26/2007 56 Female 112 lb 6/30/2008 Physician Japan
Primary
Secondary
Concomitant
Visual Impairment Hospitalization 3/18/2008 7/8/2008 Consumer United States
Primary
Concomitant
Bone Pain Other Serious 1/10/2008 30 Male 7/14/2008 Physician Belgium
Primary
Concomitant
Therapeutic Response Decreased Other Serious 12/7/2006 42 Female 7/23/2008 Physician Japan
Primary
Concomitant
Bone Pain Other Serious 1/10/2008 30 Male 8/7/2008 Physician Belgium
Primary
Concomitant
Jaundice Hospitalization 7/21/2008 52 Male 278 lb 8/11/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Bone Pain Other Serious 1/10/2008 30 Male 8/29/2008 Physician Belgium
Primary
Concomitant
Tumour Lysis Syndrome Hospitalization 8/4/2008 53 Female 115 lb 9/1/2008 Physician Japan
Primary
Concomitant
Tumour Lysis Syndrome Life Threatening 8/4/2008 53 Female 115 lb 9/3/2008 Physician Japan
Primary
Concomitant
Bone Pain Other Serious 1/10/2008 30 Male 9/11/2008 Physician Belgium
Primary
Concomitant
Urinary Tract Infection Other Serious 2/18/2008 64 Male 9/8/2008 Physician United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 8/4/2008 53 Female 115 lb 9/11/2008 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 8/1/2008 69 Male 165 lb 9/22/2008 Physician Germany
Primary
Concomitant
Stomatitis Hospitalization 9/14/2008 Female 10/8/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Gout Disability 5/2/2008 22 Female 99 lb 10/9/2008 Physician India
Primary
Secondary
Concomitant
Stomatitis Hospitalization 9/14/2008 Female 10/17/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Renal Failure Other Serious 1/1/2008 73 Female 10/31/2008 Physician Italy
Primary
Concomitant
Inflammatory Bowel Disease Hospitalization 10/13/2008 56 Male 11/3/2008 Consumer United States
Primary
Concomitant
Colitis Ischaemic Hospitalization 10/13/2008 56 Male 11/6/2008 Consumer United States
Primary
Concomitant
Sepsis Hospitalization 9/2/2008 Male 11/14/2008 Physician United States
Primary
Concomitant
Urinary Retention Hospitalization 7/28/2008 65 Male 207 lb 11/11/2008 United States
Primary
Secondary
Concomitant
Urinary Retention Hospitalization 7/28/2008 65 Male 207 lb 11/14/2008 United States
Primary
Secondary
Concomitant
Respiratory Failure Life Threatening 6/24/2008 Female 163 lb 6/29/2008 Pharmacist United States
Primary
Concomitant
Urinary Retention Hospitalization 7/28/2008 65 Male 207 lb 11/20/2008 United States
Primary
Secondary
Concomitant
Extrapyramidal Disorder Other Serious 11/4/2008 Male 12/8/2008 Other Health Professional Japan
Primary
Concomitant
Panic Attack Other Serious Male 12/22/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 9/18/2008 Male 187 lb 1/14/2009 Physician Portugal
Primary
Concomitant
Pancytopenia Life Threatening 11/20/2008 24 Male 140 lb 1/26/2009 Physician United States
Primary
Secondary
Concomitant
Pneumonia Cryptococcal Hospitalization 11/22/2008 Male 220 lb 2/9/2009 United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 2/2/2007 56 Male 181 lb 2/13/2009 Physician Japan
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 10/1/2008 Female 116 lb 3/3/2009 United States
Primary
Secondary
Concomitant
Respiratory Failure Life Threatening 9/28/2006 68 Male 181 lb 3/20/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 10/1/2008 57 Female 116 lb 3/26/2009 United States
Primary
Secondary
Concomitant
Platelet Count Decreased Other Serious 2/3/2007 60 Male 132 lb 4/10/2009 Physician Japan
Primary
Concomitant
Melaena Other Serious 3/25/2008 61 Male 5/8/2009 Physician Germany
Primary
Secondary
Concomitant
Sepsis Life Threatening 10/7/2008 77 Male 121 lb 5/29/2009 Physician Hungary
Primary
Secondary
Concomitant
Salivary Hypersecretion Hospitalization 9/1/2008 Male 165 lb 6/9/2009 Germany
Primary
Secondary
Concomitant
Polyneuropathy Hospitalization 6/23/2009 46 Male 141 lb 7/14/2009 Physician Ukraine
Primary
Concomitant
Drug Interaction Hospitalization 72 Female 176 lb 7/20/2009 Pharmacist Germany
Primary
Secondary
Concomitant
Panic Attack Other Serious Male 7/24/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Tumour Lysis Syndrome Other Serious 6/27/2009 Male 143 lb 7/27/2009 United States
Primary
Concomitant
Urosepsis Hospitalization 2/4/2009 72 Female 7/28/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Interacting
Tumour Lysis Syndrome Other Serious 6/27/2009 Male 145 lb 8/7/2009 United States
Primary
Concomitant
Panic Attack Other Serious Male 8/11/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Tremor Hospitalization 6/23/2009 46 Male 141 lb 8/7/2009 Physician Ukraine
Primary
Concomitant
Neutrophil Count Decreased 11/21/2008 77 Female 8/12/2009 Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 2/2/2007 56 Male 181 lb 8/12/2009 Physician Japan
Primary
Secondary
Concomitant
Tumour Lysis Syndrome Other Serious 6/27/2009 Male 145 lb 8/20/2009 United States
Primary
Concomitant
Tremor Hospitalization 6/23/2009 46 Male 141 lb 8/18/2009 Physician Ukraine
Primary
Concomitant

Drug Data