Allopurinol combined with Itraconazole

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Venoocclusive Disease Life Threatening 11/23/2005 63 Female 121 lb 1/12/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 11/29/2005 14 Male 1/25/2006 United Kingdom
Primary
Concomitant
Vomiting Hospitalization 11/29/2005 14 Male 2/15/2006 United Kingdom
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 5/13/2003 60 Male 203 lb 3/13/2006 United States
Primary
Concomitant
Sinus Bradycardia Hospitalization 3/22/2006 67 Female 148 lb 4/10/2006 Physician Italy
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Life Threatening 1/23/2006 52 Male 6/2/2006 Other Health Professional Japan
Primary
Concomitant
White Blood Cell Count Decreased Life Threatening 1/15/2006 59 Male 6/7/2006 Japan
Primary
Concomitant
Venoocclusive Liver Disease Disability 1/1/2004 61 Female 98 lb 6/7/2006 Physician Japan
Primary
Secondary
Concomitant
Skin Exfoliation Other Serious 46 Female 6/16/2006 Canada
Primary
Secondary
Concomitant
Spinal Cord Compression Other Serious 1/1/2005 56 Male 139 lb 6/26/2006 Physician Japan
Primary
Concomitant
Skin Exfoliation Other Serious 11/6/2005 46 Female 153 lb 7/25/2006 Canada
Primary
Secondary
Concomitant
Dyskinesia Disability 7/13/2006 58 Male 8/4/2006 Physician Japan
Primary
Concomitant
Myoclonus Disability 7/13/2006 58 Male 8/11/2006 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Life Threatening 1/15/2006 59 Male 9/19/2006 Japan
Primary
Secondary
Concomitant
Red Blood Cell Count Decreased Life Threatening 1/31/2006 58 Male 9/19/2006 Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 1/30/2006 59 Male 9/26/2006 Japan
Primary
Secondary
Concomitant
Sinus Bradycardia Hospitalization 3/22/2006 67 Female 148 lb 9/28/2006 Other Health Professional Italy
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 12/14/2002 Male 10/6/2006 Germany
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 6/5/2006 70 Female 10/5/2006 Japan
Primary
Concomitant
Skin Exfoliation Other Serious 11/6/2005 46 Female 11/8/2006 Pharmacist Canada
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 6/5/2006 70 Female 1/3/2007 Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 8/11/2006 56 Male 3/9/2007 United States
Primary
Secondary
Concomitant
Hypoxia Life Threatening 3/10/2007 Female 147 lb 3/28/2007 Physician Australia
Primary
Concomitant
Hypoxia Life Threatening 3/10/2007 Female 147 lb 3/29/2007 Physician Australia
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 8/11/2006 56 Male 4/19/2007 Japan
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 2/2/2007 Female 119 lb 5/18/2007 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 4/4/2007 55 Male 189 lb 5/29/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Sepsis Hospitalization 4/2/2007 63 Male 6/11/2007 Physician Japan
Primary
Concomitant
Rash Other Serious 4/2/2007 71 Male 6/15/2007 Physician Japan
Primary
Concomitant
Stomatitis Other Serious 2/23/2007 63 Male 6/15/2007 Physician Japan
Primary
Concomitant
Liver Disorder Hospitalization 4/1/2007 Male 88 lb 7/5/2007 Physician Japan
Primary
Secondary
Concomitant
Pyrexia Other Serious 6/1/2007 62 Female 95 lb 7/20/2007 Physician Japan
Primary
Secondary
Concomitant
Septic Shock Other Serious 12/6/2004 Male 168 lb 8/14/2007 Physician Italy
Primary
Secondary
Concomitant
Ventricular Tachycardia Other Serious 61 8/17/2007 Physician Japan
Primary
Concomitant
Interacting
Renal Impairment Hospitalization 7/5/2007 36 Male 174 lb 8/17/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Reperfusion Arrhythmia Other Serious 8/16/2007 72 Female 8/31/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Reperfusion Arrhythmia Life Threatening 8/16/2007 72 Female 9/5/2007 Other Health Professional United Kingdom
Primary
Concomitant
Reperfusion Arrhythmia Life Threatening 8/16/2007 72 Female 9/6/2007 United Kingdom
Primary
Secondary
Concomitant
Pyrexia Other Serious 6/1/2007 62 Female 95 lb 9/11/2007 Physician Japan
Primary
Secondary
Concomitant
Reperfusion Arrhythmia Other Serious 8/16/2007 72 Female 9/13/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Reperfusion Arrhythmia Other Serious 8/16/2007 72 Female 9/18/2007 Physician United States
Primary
Secondary
Concomitant
Rash Other Serious 4/2/2007 71 Male 141 lb 9/17/2007 Physician Japan
Primary
Concomitant
Toxic Epidermal Necrolysis Other Serious 1/1/1997 43 Male 9/18/2007 Italy
Primary
Secondary
Reperfusion Arrhythmia Other Serious 72 Female 10/5/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rash Other Serious 4/2/2007 71 Male 141 lb 10/10/2007 Physician Japan
Primary
Secondary
Concomitant
Reperfusion Arrhythmia Life Threatening 8/16/2007 72 Female 10/12/2007 United Kingdom
Primary
Secondary
Concomitant
Tachycardia Life Threatening 9/28/2007 21 Female 150 lb 10/16/2007 Physician United States
Primary
Secondary
Concomitant
Stomatitis Other Serious 2/23/2007 63 Male 10/22/2007 Physician Japan
Primary
Concomitant
Reperfusion Arrhythmia Other Serious 8/16/2007 72 Female 10/26/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Sepsis Other Serious 7/16/2007 52 Male 10/31/2007 Other Health Professional Japan
Primary
Secondary
Concomitant
Reperfusion Arrhythmia Other Serious 8/16/2007 72 Female 11/5/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Tachycardia Life Threatening 9/28/2007 21 Female 150 lb 11/21/2007 Consumer United States
Primary
Secondary
Concomitant
Confusional State Hospitalization 10/25/2007 12/6/2007 Consumer United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 1/21/2007 59 Male 152 lb 1/23/2007 Physician United States
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 1/21/2007 59 Male 152 lb 11/28/2007 Other Health Professional United States
Primary
Concomitant
Unresponsive To Stimuli Life Threatening 9/28/2007 21 Female 150 lb 12/3/2007 Physician United States
Primary
Secondary
Concomitant
Myalgia Required Intervention 2/18/2008 83 Male 169 lb 2/25/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Rash Other Serious 4/2/2007 71 Male 141 lb 3/19/2008 Physician Japan
Primary
Secondary
Concomitant
Stomatitis Other Serious 2/20/2007 63 Male 3/31/2008 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 3/21/2007 63 Female 4/2/2008 Physician Japan
Primary
Secondary
Concomitant
Death Death 4/26/2008 56 Male 208 lb 5/19/2008 Other Health Professional United Kingdom
Primary
Concomitant
Death Death 56 Male 208 lb 5/20/2008 United Kingdom
Primary
Concomitant
Pyrexia Other Serious 4/19/2008 64 Male 5/28/2008 Physician Japan
Primary
Concomitant
Urinary Incontinence Other Serious Female 5/20/2008 Other Health Professional Germany
Primary
Concomitant
Thrombocytopenia Life Threatening 7/7/2008 67 Male 143 lb 8/12/2008 Other Health Professional United Kingdom
Primary
Concomitant
Hepatic Function Abnormal Other Serious 12/1/2005 56 Male 128 lb 8/15/2008 Japan
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 7/5/2007 Male 174 lb 10/27/2008 United Kingdom
Primary
Secondary
Concomitant
Pyrexia Other Serious 2/9/2007 Male 11/3/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pyrexia Other Serious 2/9/2007 Male 11/4/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pancytopenia Death 10/22/2008 65 11/14/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 7/5/2007 Male 174 lb 12/19/2008 United Kingdom
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 7/3/2007 Male 174 lb 1/21/2009 United Kingdom
Primary
Secondary
Concomitant
Subdural Haematoma Other Serious 12/31/2008 Male 2/6/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Syncope Other Serious 12/31/2008 Male 2/20/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Syncope Other Serious 12/31/2008 Male 2/20/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Pyrexia Hospitalization 10/24/2008 Male 3/6/2009 Physician Japan
Primary
Concomitant
Pyrexia Hospitalization 10/24/2008 Male 3/16/2009 Physician Japan
Primary
Concomitant
Myelofibrosis Hospitalization 9/24/2008 67 3/17/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Septic Embolus Other Serious 3/1/2009 Female 112 lb 3/26/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Virus Serology Test Positive Death 4/17/2009 58 Female 97 lb 6/2/2009 Physician Japan
Primary
Concomitant
Virus Serology Test Positive Death 4/17/2009 58 Female 97 lb 7/10/2009 Physician Japan
Primary
Concomitant
Febrile Neutropenia Hospitalization 7/3/2009 Female 121 lb 7/28/2009 United Kingdom
Primary
Secondary
Concomitant
Pyrexia Hospitalization Male 7/31/2009 Physician United States
Primary
Concomitant
Febrile Neutropenia Hospitalization 7/3/2009 Female 121 lb 8/6/2009 United Kingdom
Primary
Secondary
Concomitant
Varicella Life Threatening 8/20/2007 58 Male 152 lb 8/10/2009 Physician Japan
Primary
Secondary
Concomitant
Neutrophil Count Decreased 11/21/2008 77 Female 8/12/2009 Japan
Primary
Secondary
Concomitant
Neutropenic Sepsis Hospitalization 1/1/2009 Male 9/4/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Graft Versus Host Disease Death 9/9/2008 Male 168 lb 9/9/2009 Physician United Kingdom
Primary
Concomitant
Neutropenic Sepsis Hospitalization 1/1/2009 Male 9/10/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Neutropenic Sepsis Hospitalization 7/12/2009 Male 9/21/2009 Physician United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Life Threatening 6/29/2009 66 Female 9/21/2009 Consumer United States
Primary
Secondary
Concomitant
Neutropenic Sepsis Hospitalization 7/3/2009 Female 121 lb 9/23/2009 United Kingdom
Primary
Secondary
Concomitant
Pyrexia Other Serious 6/1/2007 62 Female 95 lb 9/22/2009 Physician Japan
Primary
Concomitant
Pleural Effusion Life Threatening 9/3/2009 Female 10/2/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Sudden Death Other Serious 10/22/2008 65 9/30/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Viral Test Positive Hospitalization 9/22/2009 62 Male 194 lb 10/7/2009 Physician Italy
Primary
Secondary
Concomitant
Platelet Count Decreased Other Serious 3/12/2007 70 Male 157 lb 10/12/2009 Physician Japan
Primary
Concomitant
Varicella Life Threatening 8/20/2007 58 Male 152 lb 10/22/2009 Physician Japan
Primary
Concomitant
Stevens-johnson Syndrome Other Serious 9/1/2009 Male 121 lb 11/16/2009 Other Health Professional Japan
Primary
Concomitant
Weight Increased Life Threatening 8/20/2007 58 Male 152 lb 11/11/2009 Physician Japan
Primary
Concomitant
Sepsis Other Serious 7/8/2007 52 Male 11/17/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Pyrexia Other Serious 6/1/2007 62 Female 95 lb 11/24/2009 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 7/13/2009 69 Female 97 lb 12/7/2009 Physician Japan
Primary
Secondary
Concomitant
Neutrophil Count Decreased Other Serious 11/21/2008 77 Female 12/4/2009 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Increased Life Threatening 9/17/2009 73 Female 95 lb 12/15/2009 Physician Japan
Primary
Concomitant
Reperfusion Arrhythmia Other Serious 8/16/2007 72 Male 12/21/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Bradycardia Life Threatening 8/16/2007 72 Female 12/16/2009 Other Health Professional United Kingdom
Primary
Concomitant
Pyrexia Hospitalization 6/1/2009 Male 12/22/2009 Physician United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 10/22/2009 75 Female 12/18/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Pleural Effusion Life Threatening 9/1/2009 Female 145 lb 1/19/2010 Consumer United States
Primary
Secondary
Concomitant
Weight Decreased Life Threatening 7/5/2005 Male 143 lb 1/26/2010 Physician United Kingdom
Primary
Secondary
Somnolence Hospitalization 3/30/2009 59 Male 1/29/2010 Physician Japan
Primary
Concomitant
Swelling Face Life Threatening 7/1/2008 67 Male 143 lb 2/1/2010 Consumer United Kingdom
Primary
Secondary
Weight Decreased Life Threatening 7/9/2008 67 Male 1/29/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vomiting Other Serious 9/1/2009 Male 121 lb 3/15/2010 Other Health Professional Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 3/12/2007 70 Male 157 lb 4/14/2010 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 6/1/2009 Male 5/5/2010 Physician United States
Primary
Secondary
Concomitant
Vomiting Other Serious 9/1/2009 77 Male 121 lb 5/20/2010 Other Health Professional Japan
Primary
Concomitant
Lipoatrophy Other Serious 51 Male 5/26/2010 Physician United Kingdom
Primary
Concomitant
Pyrexia Other Serious 5/10/2010 64 Male 6/4/2010 Other Health Professional United Kingdom
Primary
Concomitant
Cytarabine Syndrome Life Threatening 5/10/2010 64 Male 6/18/2010 Other Health Professional United Kingdom
Primary
Concomitant
Sudden Death Other Serious 11/14/2008 76 Female 154 lb 6/23/2010 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 3/21/2007 63 Female 93 lb 6/28/2010 Physician Japan
Primary
Secondary
Concomitant
Scedosporium Infection Other Serious 11/16/2009 35 Male 132 lb 7/7/2010 Physician Japan
Primary
Secondary
Concomitant
Scedosporium Infection Other Serious 4/25/2009 34 Male 132 lb 7/20/2010 Physician Japan
Primary
Secondary
Concomitant
Urine Output Decreased Other Serious 5/17/2010 58 Male 127 lb 7/27/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Urine Output Decreased Other Serious 5/17/2010 58 Male 127 lb 8/3/2010 Physician United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 7/13/2009 69 Female 97 lb 8/5/2010 Physician Japan
Primary
Secondary
Concomitant
Urine Output Decreased Other Serious 5/17/2010 58 Male 127 lb 8/6/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Pulmonary Oedema Hospitalization 6/24/2010 72 Female 181 lb 7/23/2010 Pharmacist United States
Primary
Concomitant
Pyrexia Other Serious 1/9/2009 58 Female 97 lb 7/28/2010 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 7/13/2009 69 Female 97 lb 8/17/2010 Physician Japan
Primary
Secondary
Concomitant
Urine Output Decreased Other Serious 5/17/2010 58 Male 127 lb 8/26/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Staphylococcal Infection Other Serious 8/26/2010 63 Female 9/14/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Septic Shock Other Serious 5/21/2009 48 Female 132 lb 9/20/2010 Physician Italy
Primary
Secondary
Concomitant
Neutropenic Sepsis Other Serious 10/11/2010 72 Male 11/23/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 1/29/2010 49 Male 110 lb 12/13/2010 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 1/29/2010 49 Male 110 lb 12/13/2010 Physician Japan
Primary
Concomitant
Hiccups Death 7/30/2010 49 Male 110 lb 12/17/2010 Physician Japan
Primary
Secondary
Concomitant
Grand Mal Convulsion Other Serious 12/19/2010 84 Male 141 lb 1/14/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Staphylococcal Infection Other Serious 8/26/2010 63 Female 1/28/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Disseminated Intravascular Coagulation Life Threatening 4/25/2009 34 Male 132 lb 1/18/2011 Physician Japan
Primary
Secondary
Concomitant
Bone Marrow Failure Other Serious 8/26/2010 63 Female 2/10/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Hepatic Enzyme Increased Other Serious 7/8/2009 45 Male 1/26/2011 Consumer United States
Primary
Secondary
Concomitant
Grand Mal Convulsion Death 12/19/2010 84 Male 141 lb 3/7/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Pneumonia Bacterial Death 11/17/2007 58 Male 192 lb 4/14/2011 Physician Japan
Primary
Secondary
Concomitant
Pneumonia Bacterial Life Threatening 11/17/2007 58 Male 192 lb 4/14/2011 Physician Japan
Primary
Secondary
Concomitant
Leukocytosis Life Threatening 12/22/2007 20 Female 4/28/2011 Pharmacist China
Primary
Concomitant
Disseminated Intravascular Coagulation Death 7/30/2010 49 Male 110 lb 5/20/2011 Physician Japan
Primary
Secondary
Concomitant
Petechiae Other Serious 1/29/2010 49 Male 110 lb 5/20/2011 Physician Japan
Primary
Concomitant

Drug Data