Allopurinol combined with Isosorbide

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Cardiac Arrest Death 12/19/2005 83 Male 1/5/2006 Physician
Primary
Concomitant
White Blood Cell Count Increased Other Serious 6/6/2001 68 Male 1/27/2006 Physician United States
Primary
Concomitant
Ventricular Hypertrophy Other Serious 12/19/2005 83 Male 2/1/2006 Physician
Primary
Concomitant
Nephrolithiasis Other Serious 1/1/2000 49 Male 205 lb 2/21/2006 Lawyer United States
Primary
Concomitant
Nephrolithiasis Other Serious 1/1/2000 49 Male 205 lb 2/28/2006 Physician United States
Primary
Concomitant
Thyroid Disorder Hospitalization 1/1/2000 72 Female 141 lb 3/6/2006 Lawyer United States
Primary
Concomitant
Weight Decreased Hospitalization 1/1/2006 51 Male 278 lb 3/21/2006 Physician United States
Primary
Concomitant
Swelling Other Serious 1/1/2004 62 Female 143 lb 4/5/2006 Lawyer United States
Primary
Concomitant
Myositis Other Serious 84 Male 180 lb 4/13/2006 Pharmacist United States
Primary
Concomitant
White Blood Cell Count Increased Other Serious 6/6/2001 68 Male 4/21/2006 Physician United States
Primary
Concomitant
Ureteric Injury Hospitalization 6/6/2001 67 Male 231 lb 5/1/2006 Physician United States
Primary
Concomitant
Thyroid Disorder Hospitalization 1/1/2000 72 Female 141 lb 5/1/2006 Lawyer United States
Primary
Concomitant
Urticaria 10/1/2005 52 Female 306 lb 4/3/2006 United States
Primary
Concomitant
Nervousness 6/1/2005 69 Female 139 lb 6/8/2006 Consumer United States
Primary
Concomitant
Oedema Peripheral 80 Male 7/21/2006 Consumer United States
Primary
Concomitant
Fluid Retention Male 7/21/2006 Consumer United States
Primary
Concomitant
International Normalised Ratio Increased Hospitalization 4/25/2006 Male 203 lb 4/26/2006 Pharmacist United States
Primary
Concomitant
Non-cardiac Chest Pain Hospitalization 4/17/2006 75 Male 179 lb 10/4/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombosis Life Threatening 6/28/2006 78 Male 230 lb 8/25/2006 Pharmacist United States
Primary
Concomitant
Tinnitus 11/13/2006 Consumer United States
Primary
Concomitant
Sinusitis Other Serious 12/1/2005 Male 12/5/2006 Consumer United States
Primary
Concomitant
Central Nervous System Lymphoma Hospitalization 70 Female 12/1/2006 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Coeliac Disease Hospitalization 11/1/2006 76 Male 12/1/2006 United States
Primary
Concomitant
Weight Decreased 1/1/2006 72 Male 265 lb 10/16/2006 Consumer United States
Primary
Concomitant
Rectal Haemorrhage Hospitalization 12/28/2006 55 Male 146 lb 1/3/2007 Pharmacist United States
Primary
Secondary
Concomitant
Urine Output Decreased Hospitalization 3/9/2007 89 Male 156 lb 3/29/2007 Pharmacist United States
Primary
Secondary
Concomitant
No Adverse Effect Hospitalization 1/9/2007 75 Male 214 lb 3/22/2007 Physician United States
Primary
Secondary
Concomitant
Rash Required Intervention 12/14/2006 54 Male 12/29/2006 Pharmacist United States
Primary
Secondary
Concomitant
Wrong Technique In Drug Usage Process Other Serious 1/1/2007 81 Female 216 lb 4/19/2007 Physician United States
Primary
Concomitant
Haemoglobin Decreased Hospitalization 3/1/2007 78 Female 4/21/2007 United States
Primary
Concomitant
Renal Failure Acute Hospitalization 5/28/2006 Male 5/7/2007 Physician Australia
Primary
Secondary
Concomitant
Respiratory Arrest Life Threatening 3/27/2007 62 Male 260 lb 5/9/2007 Consumer United States
Primary
Concomitant
Weight Decreased Hospitalization 3/20/2007 71 Male 204 lb 5/4/2007 Consumer United States
Primary
Secondary
Concomitant
Sinus Congestion Other Serious 5/1/2007 48 Female 381 lb 9/4/2007 Other Health Professional United States
Primary
Concomitant
Weight Decreased Death 5/21/2008 79 Female 243 lb 8/20/2008 Consumer United States
Primary
Concomitant
Incorrect Dose Administered 1/1/2008 81 Male 194 lb 8/15/2008 Physician United States
Primary
Concomitant
Peripheral Vascular Disorder Hospitalization 60 Male 276 lb 9/23/2008 Lawyer United States
Primary
Concomitant
Pancytopenia Other Serious 6/1/2008 Male 10/21/2008 Physician United States
Primary
Concomitant
Visual Impairment Hospitalization 86 Female 10/29/2008 United States
Primary
Concomitant
Pancytopenia Other Serious 6/1/2008 76 Male 11/25/2008 Physician United States
Primary
Concomitant
Diverticulitis 5/1/2008 65 Male 185 lb 12/17/2008 United States
Primary
Concomitant
Tendon Disorder Other Serious 1/1/2005 72 Female 139 lb 3/9/2009 Physician United States
Primary
Concomitant
Platelet Count Decreased Hospitalization 2/26/2009 63 Male 3/12/2009 Consumer United States
Primary
Concomitant
Epistaxis Hospitalization 4/1/2008 79 Male 3/18/2009 Other Health Professional United States
Primary
Concomitant
Tendon Disorder Other Serious 1/1/2005 72 Female 139 lb 3/26/2009 Physician United States
Primary
Concomitant
Loss Of Consciousness Other Serious 1/1/2008 Male 167 lb 3/30/2009 Consumer United States
Primary
Concomitant
Tendon Disorder Other Serious 1/1/2005 72 Female 139 lb 3/31/2009 Physician United States
Primary
Concomitant
Pancreatitis Hospitalization 3/1/2009 Male 197 lb 4/14/2009 Physician United States
Primary
Concomitant
Hernia Hospitalization 69 Male 146 lb 5/7/2009 Other Health Professional United States
Primary
Concomitant
Pyrexia Hospitalization 3/1/2009 59 Male 5/14/2009 Other Health Professional United States
Primary
Concomitant
Therapeutic Agent Toxicity Other Serious 78 Female 6/5/2009 Lawyer United States
Primary
Concomitant
Vomiting Other Serious 5/1/2008 79 Female 4/6/2009 Consumer United States
Primary
Concomitant
Central Nervous System Lymphoma Hospitalization 70 Female 7/2/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Central Nervous System Lymphoma Hospitalization 70 Female 7/2/2009 Consumer United States
Primary
Secondary
Concomitant
Unevaluable Event Death 67 Male 6/30/2009 Lawyer United States
Primary
Concomitant
Thrombocytopenia Other Serious 1/9/2007 Male 174 lb 7/21/2009 Physician United States
Primary
Concomitant
International Normalised Ratio Decreased 10/1/2008 89 Male 7/22/2009 Consumer United States
Primary
Concomitant
International Normalised Ratio Decreased 10/1/2008 89 Male 168 lb 7/22/2009 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 76 Male 7/22/2009 Lawyer United States
Primary
Concomitant
Unevaluable Event Hospitalization 7/1/2007 48 Male 7/28/2009 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2007 Male 296 lb 7/31/2009 Physician United States
Primary
Concomitant
Vomiting Hospitalization 85 Female 8/3/2009 United States
Primary
Concomitant
Renal Disorder Death 67 Male 8/3/2009 Lawyer United States
Primary
Concomitant
Vomiting Hospitalization 7/1/2007 48 Male 456 lb 9/1/2009 United States
Primary
Concomitant
Weight Decreased Other Serious 76 Male 9/1/2009 Lawyer United States
Primary
Concomitant
Vomiting Hospitalization 7/1/2007 48 Male 456 lb 9/4/2009 United States
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Hospitalization 11/23/2007 66 Male 802 lb 9/3/2009 Lawyer United States
Primary
Concomitant
Therapeutic Agent Toxicity Other Serious 78 Female 9/3/2009 United States
Primary
Concomitant
Therapeutic Agent Toxicity Other Serious 78 Female 9/15/2009 United States
Primary
Concomitant
Hypotension Other Serious 1/1/2009 Male 9/23/2009 Consumer United States
Primary
Concomitant
Weight Increased Hospitalization 7/1/2007 48 Male 456 lb 9/17/2009 Consumer United States
Primary
Concomitant
Varices Oesophageal Hospitalization 11/23/2007 64 Male 364 lb 9/18/2009 United States
Primary
Concomitant
Weight Increased Hospitalization 7/1/2007 48 Male 456 lb 9/23/2009 United States
Primary
Concomitant
Platelet Count Decreased Other Serious 1/1/2009 Female 185 lb 10/7/2009 Consumer United States
Primary
Concomitant
Weight Increased Hospitalization 7/1/2007 48 Male 456 lb 10/10/2009 United States
Primary
Concomitant
Weight Increased Hospitalization 7/1/2007 48 Male 456 lb 10/16/2009 Lawyer United States
Primary
Concomitant
Platelet Count Decreased Other Serious 1/1/2009 Female 185 lb 10/29/2009 Consumer United States
Primary
Concomitant
Vomiting Other Serious 78 Female 10/27/2009 Lawyer United States
Primary
Concomitant
Sluggishness 69 Male 11/13/2009 Consumer United States
Primary
Secondary
Concomitant
Pneumonia Other Serious 9/1/2009 64 Male 11/23/2009 Other Health Professional United States
Primary
Concomitant
Pruritus Male 210 lb 11/25/2009 United States
Primary
Concomitant
Renal Failure Acute Other Serious 6/28/2007 60 Male 11/25/2009 Consumer United States
Primary
Secondary
Concomitant
Waist Circumference Increased Hospitalization 72 Male 256 lb 11/16/2009 United States
Primary
Concomitant
Pancreatitis Hospitalization 6/29/2007 Male 11/30/2009 Physician United States
Primary
Concomitant
Wound Complication Other Serious 1/1/2000 Female 12/1/2009 Physician United States
Primary
Concomitant
Weight Increased Other Serious 1/1/2006 Male 12/1/2009 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2007 Male 296 lb 12/1/2009 Physician United States
Primary
Concomitant
Wound Secretion Hospitalization Male 12/1/2009 Lawyer United States
Primary
Concomitant
Peritonitis Other Serious 3/31/2009 62 Female 11/3/2009 Other Health Professional United States
Primary
Concomitant
Hyponatraemia Other Serious 1/1/2009 64 Male 268 lb 12/16/2009 Physician United States
Primary
Concomitant
Urinary Retention Hospitalization 61 Male 12/10/2009 United States
Primary
Concomitant
Unevaluable Event Hospitalization 79 Male 12/11/2009 United States
Primary
Concomitant
Urinary Retention Hospitalization 61 Male 12/23/2009 Lawyer United States
Primary
Concomitant
Weight Decreased Other Serious 61 Male 236 lb 1/11/2010 United States
Primary
Concomitant
Ageusia 1/7/2010 90 Female 190 lb 1/26/2010 United States
Primary
Concomitant
Drug Dispensing Error 8/9/2009 Male 2/1/2010 Physician United States
Primary
Concomitant
Type 2 Diabetes Mellitus Hospitalization 79 Male 1/23/2010 Lawyer United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2003 Male 250 lb 2/3/2010 Other Health Professional United States
Primary
Concomitant
Vomiting Other Serious 78 Female 1/22/2010 United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2003 Male 250 lb 2/12/2010 Other Health Professional United States
Primary
Concomitant
Hepatic Failure Hospitalization Female 2/18/2010 Consumer United States
Primary
Concomitant
Treatment Noncompliance Hospitalization 72 Male 256 lb 2/5/2010 United States
Primary
Concomitant
Waist Circumference Increased Hospitalization 72 Male 256 lb 2/5/2010 United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2003 Male 250 lb 3/1/2010 Other Health Professional United States
Primary
Concomitant
Ageusia Other Serious 1/7/2010 50 Male 150 lb 2/22/2010 United States
Primary
Secondary
Concomitant
Visual Acuity Reduced Other Serious 2/28/2010 Male 143 lb 3/8/2010 Consumer United States
Primary
Concomitant
Visual Acuity Reduced Other Serious 2/28/2010 Male 143 lb 3/15/2010 Consumer United States
Primary
Concomitant
Renal Failure Acute Other Serious 6/28/2007 60 Male 3/24/2010 Consumer United States
Primary
Secondary
Concomitant
Visual Acuity Reduced Other Serious 2/28/2010 88 Male 143 lb 4/22/2010 Consumer United States
Primary
Concomitant
Upper Respiratory Tract Infection Other Serious 12/30/2009 69 Female 4/27/2010 Other Health Professional United States
Primary
Concomitant
Urinary Retention Other Serious 60 Male 236 lb 4/22/2010 Consumer United States
Primary
Secondary
Concomitant
Myocardial Infarction Death 4/1/2010 70 Male 176 lb 5/27/2010 Other Health Professional United States
Primary
Concomitant
Muscle Spasms Other Serious 2/1/2010 77 Female 6/11/2010 Physician United States
Primary
Concomitant
Drug Ineffective Male 6/29/2010 Other Health Professional United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 5/11/2006 69 Male 202 lb 7/5/2010 United States
Primary
Concomitant
Nausea 7/1/2007 67 Female 160 lb 7/14/2010 Consumer United States
Primary
Concomitant
Weight Increased Other Serious 7/1/2010 54 Male 254 lb 7/20/2010 Consumer United States
Primary
Concomitant
Vitreous Haemorrhage Other Serious 11/3/2001 57 Female 325 lb 7/22/2010 Physician United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 5/11/2006 69 Male 202 lb 7/22/2010 United States
Primary
Concomitant
Muscle Spasms 77 Female 7/22/2010 Physician United States
Primary
Concomitant
Low Density Lipoprotein Increased 1/11/2008 59 Male 205 lb 7/31/2010 Pharmacist United States
Primary
Concomitant
Neuropathy Peripheral 1/2/2002 77 Male 196 lb 7/31/2010 Consumer United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 85 Female 7/26/2010 United States
Primary
Concomitant
Vomiting Other Serious 75 Female 7/26/2010 Consumer United States
Primary
Concomitant
Tachycardia Death 7/23/2010 65 Male 8/9/2010 Physician United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 5/11/2006 69 Male 202 lb 8/25/2010 United States
Primary
Concomitant
Flushing 7/1/2009 77 Male 8/27/2010 United States
Primary
Concomitant
Flushing 10/16/2009 70 Female 200 lb 8/28/2010 United States
Primary
Concomitant
Pruritus Generalised 1/1/1999 56 Male 204 lb 8/28/2010 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2003 54 Male 250 lb 8/30/2010 Other Health Professional United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 5/11/2006 69 Male 202 lb 8/28/2010 United States
Primary
Concomitant
Unresponsive To Stimuli Other Serious 1/16/2007 78 Female 130 lb 9/2/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vitreous Haemorrhage Other Serious 2/6/2000 57 Female 325 lb 9/3/2010 Physician United States
Primary
Concomitant
Death Death Male 238 lb 9/9/2010 Consumer United States
Primary
Concomitant
Vision Blurred Other Serious 1/1/2010 69 Male 210 lb 9/14/2010 Physician United States
Primary
Concomitant
Muscular Weakness Other Serious 5/2/2010 87 Male 209 lb 9/14/2010 Consumer United States
Primary
Concomitant
Weight Increased Other Serious 7/1/2010 54 Male 254 lb 9/15/2010 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious Male 9/23/2010 United States
Primary
Concomitant
Vitreous Haemorrhage Other Serious 2/6/2000 57 Female 325 lb 10/6/2010 Physician United States
Primary
Concomitant
Coronary Artery Disease Death Male 238 lb 10/12/2010 Other Health Professional United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2008 72 Male 225 lb 3/21/2011 Consumer United States
Primary
Concomitant
Poor Quality Sleep Other Serious 1/1/2008 72 Male 225 lb 4/19/2011 Consumer United States
Primary
Concomitant
Thrombosis Other Serious 3/8/2011 76 Male 5/30/2011 Other Health Professional United States
Primary
Concomitant
Arrhythmia Death 1/1/2006 58 Male 235 lb 6/17/2011 Other Health Professional United States
Primary
Concomitant
Thrombosis Other Serious 3/8/2011 76 Male 7/11/2011 Physician United States
Primary
Concomitant
Hypertension Hospitalization 3/8/2011 76 Male 12/2/2011 Other Health Professional United States
Primary
Concomitant
Loss Of Consciousness Other Serious 1/1/2008 63 Female 240 lb 1/9/2012 Consumer United States
Primary
Concomitant
Dyskinesia Other Serious 5/1/2010 65 Female 240 lb 1/17/2012 Consumer United States
Primary
Secondary
Concomitant
Loss Of Consciousness Other Serious 1/1/2008 63 Female 240 lb 1/17/2012 Consumer United States
Primary
Concomitant
Blood Potassium Increased Other Serious 11/24/2011 67 Female 240 lb 1/17/2012 Consumer United States
Primary
Secondary
Concomitant

Drug Data