Allopurinol combined with Isosorbide Mononitrate

Reports:


Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Movement Disorder Hospitalization 1/2/2006 71 Male 1/11/2006 Physician Japan
Primary
Concomitant
Treatment Noncompliance Hospitalization 11/30/2005 Male 153 lb 1/3/2006 Other Health Professional United States
Primary
Concomitant
Parkinsonism Hospitalization 9/5/2005 52 Male 2/6/2006 Germany
Primary
Secondary
Concomitant
Ischaemic Stroke Hospitalization 9/1/2004 77 Female 190 lb 2/16/2006 Physician United States
Primary
Concomitant
Vomiting Hospitalization 2/6/2006 59 Male 128 lb 2/23/2006 Physician Germany
Primary
Secondary
Concomitant
Odynophagia Hospitalization 1/15/2006 71 Male 3/10/2006 Physician Japan
Primary
Secondary
Angioneurotic Oedema Hospitalization 1/15/2006 71 Male 3/17/2006 Physician Japan
Primary
Secondary
Vomiting Hospitalization 2/6/2006 59 Male 128 lb 3/30/2006 Physician Germany
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 1/15/2006 71 Male 4/3/2006 Physician Japan
Primary
Secondary
Rectal Haemorrhage Other Serious 3/11/2006 72 Male 4/12/2006 Consumer United States
Primary
Concomitant
Sepsis Hospitalization 2/6/2006 59 Male 128 lb 4/5/2006 Physician Germany
Primary
Secondary
Concomitant
Rash Other Serious 2/1/2006 70 Male 4/3/2006 Physician United States
Primary
Concomitant
Rash Other Serious 2/1/2006 70 Male 4/7/2006 Physician United States
Primary
Concomitant
Weight Increased 9/14/2005 63 Female 225 lb 4/14/2006 Physician United States
Primary
Concomitant
Vomiting Hospitalization 2/6/2006 59 Male 128 lb 4/18/2006 Other Health Professional Germany
Primary
Secondary
Concomitant
Fall Other Serious 2/1/2006 92 Male 4/26/2006 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Death 7/30/2005 66 Male 203 lb 5/3/2006 Other Health Professional Hungary
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 9/29/2003 Male 5/16/2006 United States
Primary
Secondary
Concomitant
Fall Other Serious 2/1/2006 92 Male 5/23/2006 Japan
Primary
Secondary
Concomitant
Large Intestinal Ulcer Other Serious 4/5/2006 50 Male 218 lb 4/7/2006 Pharmacist United States
Primary
Concomitant
Liver Disorder Hospitalization 3/8/2004 Female 177 lb 6/5/2006 Physician Japan
Primary
Secondary
Concomitant
Chest Pain Hospitalization 10/31/2004 89 Female 6/8/2006 Other Health Professional Sweden
Primary
Secondary
Concomitant
Thrombotic Stroke Hospitalization 7/1/2005 62 Male 6/16/2006 Physician Japan
Primary
Concomitant
Hallucination Hospitalization 11/1/2001 74 Male 6/23/2006 Other Health Professional Sweden
Primary
Concomitant
Vomiting Hospitalization 2/10/2004 81 Male 157 lb 7/2/2006 Physician Japan
Primary
Concomitant
Renal Failure Acute Hospitalization 6/9/2006 56 Male 205 lb 6/23/2006 Physician Brazil
Primary
Concomitant
Weight Increased Hospitalization 4/13/2006 67 Male 6/29/2006 Physician United States
Primary
Secondary
Concomitant
Liver Disorder Hospitalization 3/8/2004 Female 177 lb 7/11/2006 Physician Japan
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 6/9/2006 56 Male 205 lb 7/5/2006 Physician Brazil
Primary
Concomitant
Tachypnoea Life Threatening 6/1/2006 72 Female 97 lb 7/13/2006 Physician Japan
Primary
Concomitant
Hyperkalaemia Hospitalization 5/23/2006 92 Male 7/7/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Gallbladder Cancer Hospitalization 3/14/2006 Male 7/14/2006 Physician Japan
Primary
Concomitant
Hypoglycaemia Hospitalization 7/5/2005 69 Male 5/8/2006 United States
Primary
Secondary
Concomitant
Renal Impairment Disability 4/7/2006 77 Male 128 lb 7/21/2006 Physician Japan
Primary
Concomitant
Hypertension Other Serious 1/1/2000 73 Male 217 lb 7/19/2006 Consumer United Kingdom
Primary
Concomitant
Syncope Hospitalization 5/1/2006 75 Male 7/25/2006 United States
Primary
Secondary
Concomitant
Prothrombin Time Prolonged Hospitalization 6/1/2006 69 Male 8/10/2006 Physician Japan
Primary
Secondary
Concomitant
Sepsis Hospitalization 7/20/2006 56 Male 203 lb 8/10/2006 Physician Brazil
Primary
Concomitant
Renal Failure Other Serious 3/3/2006 78 Male 141 lb 8/11/2006 Other Health Professional Japan
Primary
Concomitant
Retroperitoneal Haemorrhage Other Serious 9/17/2004 74 Female 141 lb 8/28/2006 Australia
Primary
Secondary
Concomitant
Sepsis Hospitalization 7/20/2006 56 Male 203 lb 8/22/2006 Physician Brazil
Primary
Concomitant
Sepsis Hospitalization 7/18/2006 56 Male 203 lb 9/1/2006 Brazil
Primary
Concomitant
Drug Interaction Other Serious 7/22/2006 74 Male 9/1/2006 Pharmacist Japan
Primary
Secondary
Concomitant
Sepsis Hospitalization 7/18/2006 56 Male 203 lb 9/1/2006 Brazil
Primary
Concomitant
Drug Interaction Other Serious 7/22/2006 74 Male 9/1/2006 Pharmacist Japan
Primary
Secondary
Concomitant
Rhinorrhoea Hospitalization 8/8/2006 60 Male 234 lb 9/12/2006 Other Health Professional Poland
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 7/18/2006 56 Male 203 lb 9/18/2006 Other Health Professional Brazil
Primary
Concomitant
Steatorrhoea Life Threatening Male 230 lb 9/25/2006 Physician United Kingdom
Primary
Concomitant
Stevens-johnson Syndrome Hospitalization 5/11/2006 79 Female 154 lb 10/3/2006 Other Health Professional United Kingdom
Primary
Concomitant
Thrombocytopenia Other Serious 7/18/2006 56 Male 203 lb 9/27/2006 Other Health Professional Brazil
Primary
Concomitant
Vomiting Hospitalization 2/7/2006 59 Male 128 lb 9/27/2006 Physician Germany
Primary
Secondary
Concomitant
Stevens-johnson Syndrome Hospitalization 79 Female 154 lb 9/29/2006 United Kingdom
Primary
Concomitant
Muscle Haemorrhage Death 7/1/2006 78 Male 132 lb 10/6/2006 Physician Portugal
Primary
Concomitant
Renal Failure Hospitalization 78 Male 99 lb 10/10/2006 Consumer United States
Primary
Concomitant
Tachypnoea Life Threatening 6/1/2006 72 Female 97 lb 10/11/2006 Physician Japan
Primary
Concomitant
Thrombocytopenia Other Serious 7/18/2006 56 Male 203 lb 10/10/2006 Other Health Professional Brazil
Primary
Concomitant
Prothrombin Time Prolonged Other Serious 6/1/2006 69 Male 10/13/2006 Physician Japan
Primary
Secondary
Concomitant
Nodal Rhythm Hospitalization 9/25/2006 80 Female 10/16/2006 Physician Poland
Primary
Secondary
Concomitant
Myocardial Infarction Hospitalization 9/14/2006 Male 10/23/2006 Pharmacist United States
Primary
Concomitant
Restlessness Hospitalization 9/20/2006 71 Male 95 lb 10/30/2006 Physician Japan
Primary
Concomitant
Duodenal Ulcer Haemorrhage Other Serious 8/30/2006 67 Male 10/25/2006 Japan
Primary
Concomitant
Somnolence Hospitalization 9/20/2006 71 Male 95 lb 11/13/2006 Physician Japan
Primary
Concomitant
Renal Impairment Disability 4/7/2006 77 Male 128 lb 11/20/2006 Physician Japan
Primary
Concomitant
Vomiting Other Serious 10/21/2006 85 Female 12/6/2006 Other Health Professional United Kingdom
Primary
Concomitant
Ventricular Hypertrophy Death 61 Male 11/30/2006 Austria
Primary
Secondary
Ventricular Hypertrophy Hospitalization Male 12/7/2006 Physician Austria
Primary
Concomitant
Vomiting Other Serious 10/21/2006 85 Female 12/11/2006 Other Health Professional United Kingdom
Primary
Concomitant
Thrombocytopenia Other Serious 7/18/2006 56 Male 203 lb 12/13/2006 Other Health Professional Brazil
Primary
Concomitant
Tremor 1/1/2006 78 Male 233 lb 10/19/2006 United States
Primary
Concomitant
Weight Decreased Hospitalization 87 Male 2/7/2007 Physician Spain
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 87 Male 3/13/2007
Primary
Secondary
Concomitant
Low Density Lipoprotein Decreased Other Serious 62 Male 11/28/2006 United States
Primary
Concomitant
Renal Failure Acute Hospitalization 6/8/2006 Male 205 lb 3/30/2007 Brazil
Primary
Concomitant
Thrombocytopenia Other Serious 7/21/2006 Male 203 lb 4/2/2007 Brazil
Primary
Concomitant
Vomiting Hospitalization 1/1/2005 80 Female 4/5/2007 Other Health Professional Sweden
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 7/18/2006 Male 203 lb 4/13/2007 Brazil
Primary
Concomitant
Sclerosing Encapsulating Peritonitis Hospitalization 8/4/2005 56 Male 165 lb 4/18/2007 Japan
Primary
Secondary
Concomitant
Sclerosing Encapsulating Peritonitis Hospitalization 8/4/2005 56 Male 165 lb 4/18/2007 Japan
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 84 Female 181 lb 5/14/2007 Other Health Professional United Kingdom
Primary
Concomitant
Weight Decreased Other Serious 9/1/2003 87 Male 5/9/2007 Physician United States
Primary
Concomitant
Pallor Hospitalization 5/11/2006 79 Female 154 lb 5/18/2007 Other Health Professional United Kingdom
Primary
Concomitant
Visual Acuity Reduced 3/1/2006 80 Male 138 lb 2/22/2007 United States
Primary
Concomitant
Therapeutic Response Unexpected 1/1/2007 78 Female 5/17/2007 Other Health Professional United States
Primary
Concomitant
Thrombocytopenia Hospitalization 7/18/2006 Male 203 lb 6/28/2007 Brazil
Primary
Concomitant
Venous Thrombosis Hospitalization 3/14/2007 Male 7/2/2007 Physician Czech Republic
Primary
Concomitant
Weight Decreased Other Serious 80 Male 7/16/2007 Physician Switzerland
Primary
Concomitant
Orthostatic Hypotension Hospitalization 6/7/2007 89 Female 7/26/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Orthostatic Hypotension Hospitalization 6/7/2007 89 Female 7/24/2007 Other Health Professional United Kingdom
Primary
Concomitant
Orthostatic Hypotension Hospitalization 6/7/2007 89 Female 7/27/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Orthostatic Hypotension Hospitalization 89 Female 7/30/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Orthostatic Hypotension Hospitalization 6/7/2007 89 Female 7/18/2007 United Kingdom
Primary
Secondary
Concomitant
Blood Glucose Increased Hospitalization 7/17/2007 83 Male 8/17/2007 Consumer United States
Primary
Concomitant
Sepsis Hospitalization 2/6/2006 Male 128 lb 9/21/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Therapeutic Response Unexpected 1/1/2007 78 Female 8/16/2007 Other Health Professional United States
Primary
Concomitant
Venous Thrombosis Hospitalization 3/14/2007 Male 10/4/2007 Physician Czech Republic
Primary
Concomitant
Renal Failure Acute Life Threatening 4/25/2003 68 Female 137 lb 10/10/2007 Physician Australia
Primary
Secondary
Concomitant
Unresponsive To Stimuli Hospitalization 1/6/2007 60 Male 10/12/2007 Physician United States
Primary
Secondary
Concomitant
Osteonecrosis Hospitalization 12/21/2006 60 Male 10/29/2007 United States
Primary
Secondary
Concomitant
Stem Cell Transplant Life Threatening 2/9/2007 Female 86 lb 11/6/2007 Physician United States
Primary
Concomitant
Sclerosing Encapsulating Peritonitis Hospitalization 8/1/2005 Male 165 lb 11/29/2007 Japan
Primary
Secondary
Concomitant
Endotracheal Intubation Complication Life Threatening 10/3/2007 Female 165 lb 12/5/2007 Pharmacist United States
Primary
Concomitant
Ventricular Tachycardia Death 3/5/2007 88 Female 156 lb 12/7/2007 Pharmacist United States
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 1/1/2007 79 Male 2/13/2008 Other Health Professional Israel
Primary
Concomitant
Rhabdomyolysis Hospitalization 1/1/2001 73 Male 3/5/2008 Physician United Kingdom
Primary
Concomitant
Nutritional Condition Abnormal Other Serious 3/1/2008 65 Male 3/14/2008 Physician Japan
Primary
Secondary
Concomitant
Seizure Anoxic Hospitalization 12/4/2007 87 Male 3/18/2008 Other Health Professional Sweden
Primary
Concomitant
Syncope Hospitalization 3/1/2008 63 Male 4/3/2008 Physician Japan
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2007 82 Female 3/31/2008 Other Health Professional United Kingdom
Primary
Concomitant
Renal Disorder Hospitalization 66 Male 4/4/2008 Consumer United States
Primary
Concomitant
Swollen Tongue Life Threatening 10/3/2007 Female 155 lb 4/8/2008 Pharmacist United States
Primary
Secondary
Concomitant
Peritonitis Hospitalization 3/15/2008 71 Male 201 lb 4/10/2008 Physician United States
Primary
Concomitant
Syncope Hospitalization 3/14/2008 65 Male 4/15/2008 Physician Japan
Primary
Concomitant
Syncope Hospitalization 3/14/2008 64 Male 4/18/2008 Physician Japan
Primary
Concomitant
Respiratory Arrest Other Serious 1/27/2007 71 Male 141 lb 4/14/2008 Japan
Primary
Concomitant
Weight Increased Other Serious 8/29/2007 Male 5/12/2008 Consumer United States
Primary
Concomitant
Thrombocytopenia Hospitalization 7/18/2006 Male 203 lb 5/16/2008 Brazil
Primary
Concomitant
Renal Failure Other Serious 2/8/2008 Male 110 lb 5/23/2008 Physician Japan
Primary
Secondary
Concomitant
Interacting
Skin Laceration Hospitalization 5/1/2008 76 Male 195 lb 5/20/2008 United States
Primary
Secondary
Concomitant
Cardiac Failure Congestive Other Serious 9/5/2007 81 Male 6/11/2008 Japan
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 7/18/2006 Male 203 lb 6/12/2008 Brazil
Primary
Concomitant
Weight Increased Other Serious 8/1/2007 Male 6/13/2008 Consumer United States
Primary
Concomitant
Cardiomegaly Other Serious 9/11/2007 81 Male 6/27/2008 Japan
Primary
Secondary
Concomitant
Vitamin D Decreased Other Serious 6/1/2008 Female 7/10/2008 Other Health Professional United States
Primary
Concomitant
Thrombocytopenia Hospitalization 7/18/2006 Male 203 lb 7/15/2008 Brazil
Primary
Concomitant
Cardiomegaly Other Serious 9/11/2007 81 Male 7/17/2008 Japan
Primary
Secondary
Concomitant
Tremor Hospitalization 6/12/2008 77 Male 7/18/2008 Physician Switzerland
Primary
Concomitant
Cerebrovascular Accident Hospitalization 5/25/2007 80 Male 7/29/2008 Physician United States
Primary
Concomitant
No Adverse Event 65 Female 7/31/2008 Pharmacist United States
Primary
Concomitant
Cardiomegaly Other Serious 9/11/2007 81 Male 8/6/2008 Japan
Primary
Secondary
Concomitant
Vomiting Other Serious 10/21/2006 85 Female 8/9/2008 United Kingdom
Primary
Concomitant
Blood Pressure Decreased Other Serious 7/30/2008 68 Male 190 lb 8/25/2008 Other Health Professional United Kingdom
Primary
Concomitant
Vitamin D Decreased Other Serious 6/1/2008 Female 148 lb 8/26/2008 Other Health Professional United States
Primary
Concomitant
Wound Infection Staphylococcal Hospitalization 5/22/2008 48 Male 8/27/2008 Sweden
Primary
Concomitant
Headache 7/7/2008 Female 8/27/2008 United States
Primary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 6/2/2008 55 Male 194 lb 7/30/2008 Pharmacist United States
Primary
Concomitant
Stevens-johnson Syndrome Life Threatening 8/1/2008 81 Male 8/25/2008 Italy
Primary
Secondary
Concomitant
Blood Pressure Decreased Other Serious 7/30/2008 68 Male 190 lb 9/8/2008 Other Health Professional United Kingdom
Primary
Concomitant
Blood Pressure Decreased Other Serious 7/30/2008 68 Male 190 lb 9/8/2008 Other Health Professional United Kingdom
Primary
Concomitant
Wound Infection Staphylococcal Hospitalization 5/22/2008 48 Male 133 lb 9/9/2008 Sweden
Primary
Concomitant
Weight Increased Hospitalization 5/1/2008 76 Male 195 lb 9/3/2008 United States
Primary
Secondary
Concomitant
Dehydration Hospitalization 8/20/2008 Female 199 lb 9/10/2008 Consumer United States
Primary
Secondary
Concomitant
Henoch-schonlein Purpura Hospitalization 4/27/2008 Male 8/27/2008 United States
Primary
Secondary
Concomitant
Renal Failure Other Serious 2/6/2008 51 Male 9/17/2008 Lawyer United States
Primary
Concomitant
Stevens-johnson Syndrome Life Threatening 8/1/2008 81 Male 9/11/2008 Italy
Primary
Secondary
Concomitant
Dehydration Hospitalization 8/20/2008 Female 199 lb 9/19/2008 Consumer United States
Primary
Secondary
Concomitant
Sick Sinus Syndrome Hospitalization 10/6/2006 74 Male 9/25/2008 Consumer United States
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 9/25/2008 Female 10/10/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Sciatica Other Serious 8/7/2007 74 Female 198 lb 10/10/2008 Physician Australia
Primary
Concomitant
Respiratory Failure Hospitalization 4/4/2005 Male 225 lb 10/17/2008 Lawyer United States
Primary
Secondary
Concomitant
Lethargy Other Serious 4/18/2005 Male 10/17/2008 Physician United States
Primary
Concomitant