Allopurinol combined with Isosorbide Dinitrate

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Liver Disorder Hospitalization 12/14/2004 72 Female 1/6/2006 Physician Japan
Primary
Concomitant
Movement Disorder Hospitalization 1/2/2006 71 Male 1/11/2006 Physician Japan
Primary
Concomitant
Hyperkalaemia Hospitalization 10/7/2005 70 Male 191 lb 10/12/2005 Pharmacist United States
Primary
Concomitant
Ventricular Fibrillation Other Serious 12/13/2000 57 Female 179 lb 2/27/2006 Physician Germany
Primary
Concomitant
Confusional State Hospitalization 11/4/2004 92 Male 3/2/2006 Physician Norway
Primary
Concomitant
Fall Death 3/4/2006 78 Female 3/9/2006 Japan
Primary
Concomitant
Tricuspid Valve Incompetence Hospitalization 63 Male 3/16/2006
Primary
Secondary
Concomitant
Tricuspid Valve Incompetence Hospitalization 63 Male 3/21/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Tricuspid Valve Incompetence Hospitalization 63 Male 3/15/2006 Pharmacist United States
Primary
Secondary
Concomitant
Treatment Noncompliance Life Threatening 2/13/2006 71 Male 3/20/2006 Japan
Primary
Secondary
Concomitant
Sclerosing Encapsulating Peritonitis Other Serious 4/2/2005 56 Male 125 lb 3/21/2006 Physician Japan
Primary
Secondary
Concomitant
Sudden Cardiac Death Death 3/3/2006 78 Female 3/23/2006 Japan
Primary
Concomitant
Tricuspid Valve Incompetence Hospitalization 63 Male 3/28/2006 United States
Primary
Secondary
Concomitant
Tricuspid Valve Incompetence Hospitalization 63 Male 3/28/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Sudden Death Death 3/3/2006 78 Female 4/13/2006 Japan
Primary
Concomitant
Pulmonary Toxicity Required Intervention 4/26/2005 72 Male 175 lb 4/20/2006 Pharmacist United States
Primary
Concomitant
Retroperitoneal Haemorrhage Other Serious 3/8/2006 Male 164 lb 4/24/2006 Physician Japan
Primary
Concomitant
Interacting
Ventricular Fibrillation Other Serious 10/1/2000 57 Female 179 lb 4/26/2006 Physician Germany
Primary
Concomitant
Gallbladder Cancer Hospitalization 3/14/2006 Male 7/14/2006 Physician Japan
Primary
Concomitant
Sepsis Required Intervention 8/13/2005 58 Male 194 lb 7/8/2006 Pharmacist United States
Primary
Concomitant
Bradycardia Hospitalization 6/5/2006 71 Male Pharmacist United States
Primary
Concomitant
Loss Of Consciousness Hospitalization 6/15/2006 88 Male 198 lb 7/6/2006 Pharmacist United States
Primary
Concomitant
Rash Pruritic Other Serious 3/1/2005 75 Male 194 lb 8/1/2006 Consumer United States
Primary
Concomitant
White Blood Cell Count Increased Death 2/16/2006 70 Female 7/27/2006 Physician Japan
Primary
Secondary
Concomitant
Respiratory Failure Death 6/30/2005 79 Male 8/2/2006 Physician Japan
Primary
Secondary
Concomitant
Infusion Site Pain Other Serious 1/1/2005 64 Male 142 lb 9/15/2006 United States
Primary
Secondary
Concomitant
Urinary Incontinence Required Intervention 7/26/2006 55 Male 187 lb 9/21/2006 France
Primary
Secondary
Concomitant
Sepsis Other Serious 9/15/2006 75 Male 172 lb 10/26/2006 Physician Germany
Primary
Concomitant
Sepsis Other Serious 9/15/2006 75 Male 172 lb 11/3/2006 Physician Germany
Primary
Concomitant
Cerebrovascular Accident Hospitalization 78 Male 168 lb 12/1/2006 Physician Germany
Primary
Concomitant
Vomiting Hospitalization Male 12/6/2006 Consumer Japan
Primary
Secondary
Concomitant
Sclerosing Encapsulating Peritonitis Other Serious 4/2/2005 56 Male 125 lb 11/21/2006 Physician Japan
Primary
Secondary
Concomitant
Cerebrovascular Accident Hospitalization 78 Male 168 lb 12/14/2006 Physician Germany
Primary
Concomitant
Cerebrovascular Accident Hospitalization 78 Male 168 lb 12/21/2006 Physician Germany
Primary
Concomitant
Pseudarthrosis Other Serious 3/1/2005 83 Female 1/12/2007 Other Health Professional Germany
Primary
Concomitant
Tachycardia Death 1/12/2007 72 Male 1/25/2007 Physician Japan
Primary
Concomitant
Shock Life Threatening 2/8/2007 3/5/2007 Japan
Primary
Concomitant
Tachycardia Death 1/12/2007 72 Male 3/14/2007 Physician Japan
Primary
Concomitant
Shock 2/20/2007 90 Male 4/12/2007 Germany
Primary
Concomitant
Wrong Technique In Drug Usage Process Hospitalization 11/23/2006 69 Male 251 lb 11/30/2006 Pharmacist United States
Primary
Concomitant
Renal Failure Acute Other Serious 3/28/2007 75 Female 4/30/2007 Japan
Primary
Concomitant
Renal Failure Acute Other Serious 3/28/2007 75 Female 5/29/2007 Japan
Primary
Concomitant
Somnolence 1/1/2007 82 Male 160 lb 4/12/2007 Consumer United States
Primary
Concomitant
Renal Failure Acute Other Serious 3/28/2007 75 Female 5/29/2007 Japan
Primary
Concomitant
Tremor Other Serious 3/1/2007 64 Male 263 lb 4/26/2007 United States
Primary
Concomitant
Shock Life Threatening 2/8/2007 73 Female 101 lb 7/3/2007 Japan
Primary
Concomitant
Stevens-johnson Syndrome Death 4/24/2007 71 Female 6/29/2007 Japan
Primary
Secondary
Concomitant
Muscular Weakness 86 Female 8/3/2007 Consumer United States
Primary
Concomitant
Weight Increased Other Serious 1/1/2006 62 Male 183 lb 8/10/2007 Consumer United States
Primary
Concomitant
Skin Discolouration Other Serious 8/15/2007 87 Male 190 lb 8/29/2007 Consumer United States
Primary
Concomitant
Interacting
Weight Increased Life Threatening 6/1/2007 70 Male 8/31/2007 Germany
Primary
Concomitant
Pleural Effusion Life Threatening 2/13/2006 71 Male 10/1/2007 Japan
Primary
Secondary
Concomitant
Rash Other Serious 8/26/2007 10/17/2007 Physician United States
Primary
Secondary
Concomitant
Skin Discolouration Other Serious 8/15/2007 87 Male 190 lb 10/22/2007 Consumer United States
Primary
Concomitant
Interacting
Lipase Increased Hospitalization 6/1/2007 Male 10/29/2007 Physician United States
Primary
Concomitant
Chronic Obstructive Pulmonary Disease Hospitalization 10/1/2007 69 Female 11/9/2007 Consumer United Kingdom
Primary
Concomitant
Prostatic Specific Antigen Increased Male 11/13/2007 Consumer United States
Primary
Concomitant
Nocturnal Dyspnoea 8/22/2007 69 Male 11/14/2007 Consumer United States
Primary
Concomitant
Flatulence 9/18/2007 87 Male 11/16/2007 Consumer United States
Primary
Concomitant
Leg Amputation Hospitalization 8/1/2007 71 Male 11/30/2007 Physician Germany
Primary
Concomitant
Sclerosing Encapsulating Peritonitis Death 2/1/2001 56 Male 123 lb 12/12/2007 Japan
Primary
Secondary
Concomitant
Pancreatitis Hospitalization 1/1/2007 Male 12/17/2007 Physician United States
Primary
Concomitant
Drug Ineffective Male 12/21/2007 Consumer United States
Primary
Concomitant
Peripheral Arterial Occlusive Disease Hospitalization 1/1/2007 71 Male 12/28/2007 Germany
Primary
Concomitant
Refusal Of Treatment By Patient Life Threatening 12/1/2007 63 Male 1/14/2008 United States
Primary
Concomitant
Ventricular Tachycardia Life Threatening 1/1/2007 64 Male 1/21/2008 Other Health Professional United Kingdom
Primary
Concomitant
Ventricular Tachycardia Life Threatening 11/19/2007 63 Male 294 lb 1/31/2008 United States
Primary
Concomitant
Ventricular Tachycardia Life Threatening 1/1/2007 64 Male 1/30/2008 Other Health Professional United Kingdom
Primary
Concomitant
Flatulence 9/18/2007 87 Male 163 lb 2/13/2008 Consumer United States
Primary
Concomitant
Rhinorrhoea Male 2/17/2008 United States
Primary
Concomitant
Stevens-johnson Syndrome Hospitalization 6/7/2003 81 Female 2/14/2008 Physician Germany
Primary
Secondary
Stevens-johnson Syndrome Hospitalization 6/7/2003 81 Female 2/14/2008 Physician Germany
Primary
Secondary
Rhinorrhoea Male 2/27/2008 Other Health Professional United States
Primary
Concomitant
Dyspnoea 2/11/2008 71 Male 262 lb 2/27/2008 Other Health Professional United States
Primary
Concomitant
Pain Other Serious 9/20/2007 82 Male 3/4/2008 Pharmacist United States
Primary
Concomitant
Pancreatitis Hospitalization 1/1/2007 Male 3/3/2008 Physician United States
Primary
Concomitant
Renal Failure Acute Hospitalization 6/1/2006 Male 3/7/2008 Physician Australia
Primary
Secondary
Concomitant
Sinusitis Hospitalization 6/6/2006 Male 3/10/2008 Physician United States
Primary
Secondary
Concomitant
Swelling 11/1/2007 69 Male 234 lb 3/11/2008 Consumer United States
Primary
Concomitant
Urinary Tract Infection Hospitalization Male 3/5/2008 Other Health Professional United States
Primary
Concomitant
Wound Complication Other Serious 1/1/2000 Female 3/7/2008 Consumer United States
Primary
Concomitant
Pancreatitis Hospitalization 6/29/2007 Male 3/13/2008 Physician United States
Primary
Concomitant
Ventricular Tachycardia Life Threatening 1/1/2007 64 Male 3/17/2008 United Kingdom
Primary
Concomitant
Sinusitis Hospitalization 5/22/2006 Male 3/26/2008 Consumer France
Primary
Secondary
Concomitant
Pneumonia Death 9/13/2004 77 Female 220 lb 3/28/2008 United Kingdom
Primary
Concomitant
Vomiting Hospitalization 4/9/2007 85 Female 150 lb 3/7/2008 United States
Primary
Concomitant
Febrile Neutropenia Hospitalization 4/1/2008 70 Male 4/14/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 4/1/2008 70 Male 4/14/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Sinusitis Hospitalization 5/22/2006 Male 4/15/2008 Consumer France
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/2006 Male 4/10/2008 Consumer United States
Primary
Concomitant
White Blood Cell Count Abnormal Other Serious 9/25/2007 80 Female 75 lb 4/10/2008 Physician Japan
Primary
Concomitant
Pneumonia Death 9/13/2004 77 Female 220 lb 4/18/2008 United Kingdom
Primary
Concomitant
Febrile Neutropenia Hospitalization 4/1/2008 Male 4/21/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 4/1/2008 Male 4/21/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Wound Complication Other Serious 1/1/2000 Female 4/16/2008 Physician United States
Primary
Concomitant
Renal Impairment 82 Male 4/22/2008 Germany
Primary
Concomitant
Renal Disorder Hospitalization 12/1/2007 73 Female 4/30/2008 Consumer United Kingdom
Primary
Concomitant
Renal Failure Death 1/1/1990 Female 103 lb 5/8/2008 United States
Primary
Concomitant
Renal Failure Death 1/1/1990 Female 103 lb 5/15/2008 United States
Primary
Concomitant
Febrile Neutropenia Hospitalization 4/1/2008 Male 5/16/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 4/1/2008 Male 5/16/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Failure Death 1/1/1990 Female 103 lb 5/30/2008 United States
Primary
Concomitant
Renal Impairment 7/20/2007 82 Male 5/30/2008 Physician Germany
Primary
Concomitant
Weight Increased Other Serious 1/1/2006 Male 6/4/2008 Consumer United States
Primary
Concomitant
Wound Complication Other Serious 1/1/2000 Female 6/4/2008 Physician United States
Primary
Concomitant
Renal Failure Death 1/1/1990 Female 103 lb 7/15/2008 United States
Primary
Concomitant
Renal Disorder Hospitalization 12/1/2007 73 Female 7/29/2008 Consumer United Kingdom
Primary
Concomitant
Hyperkalaemia Hospitalization 11/30/2007 Male 198 lb 8/21/2008 Physician Germany
Primary
Secondary
Concomitant
Weight Decreased Other Serious 7/17/2008 58 Male 210 lb 11/7/2008 Physician United States
Primary
Concomitant
Flushing Male 11/26/2008 United States
Primary
Concomitant
Rash 11/7/2007 74 Male 11/28/2008 Physician Japan
Primary
Concomitant
Ventricular Extrasystoles Other Serious 4/1/1999 Male 12/18/2008 Pharmacist Japan
Primary
Concomitant
Chest Discomfort Life Threatening 1/5/2009 2/9/2009 Other Health Professional Singapore
Primary
Concomitant
Vasodilatation 12/26/2008 61 Male 2/20/2009 Japan
Primary
Secondary
Concomitant
Loss Of Consciousness Hospitalization 12/1/2008 Male 201 lb 3/17/2009 Consumer United States
Primary
Concomitant
Blood Creatine Phosphokinase Increased Hospitalization 10/17/2007 74 Female 5/1/2009 Physician Japan
Primary
Concomitant
Cerebrovascular Accident Hospitalization 70 Female 7/10/2009 United Kingdom
Primary
Secondary
Concomitant
Renal Disorder Death 67 Male 7/14/2009 Lawyer United States
Primary
Concomitant
Therapeutic Agent Toxicity Other Serious 78 Female 7/23/2009 United States
Primary
Concomitant
International Normalised Ratio Decreased 10/1/2008 89 Male 7/22/2009 Consumer United States
Primary
Concomitant
International Normalised Ratio Decreased 10/1/2008 89 Male 168 lb 7/22/2009 Consumer United States
Primary
Concomitant
Therapeutic Agent Toxicity Other Serious 78 Female 8/3/2009 United States
Primary
Concomitant
Varices Oesophageal Hospitalization 11/23/2007 67 Male 8/12/2009 Consumer United States
Primary
Concomitant
Vomiting Hospitalization 7/1/2007 48 Male 8/12/2009 United States
Primary
Concomitant
Unevaluable Event Other Serious 78 Female 8/14/2009 United States
Primary
Concomitant
Dizziness 5/1/2008 Male 8/21/2009 United States
Primary
Secondary
Concomitant
Pruritus 12/1/2008 Male 8/22/2009 United States
Primary
Concomitant
Intraocular Pressure Increased Other Serious 12/4/2008 77 Male 153 lb 9/11/2009 Physician Japan
Primary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 8/7/2009 49 Female 9/18/2009 Other Health Professional Italy
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 7/8/2009 57 Male 170 lb 7/10/2009 Pharmacist United States
Primary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 8/7/2009 49 Female 10/6/2009 Other Health Professional Italy
Primary
Secondary
Concomitant
Tardive Dyskinesia Other Serious 12/29/2006 59 Male 303 lb 10/8/2009 United States
Primary
Secondary
Concomitant
Intraocular Pressure Increased Other Serious 12/4/2008 77 Male 153 lb 10/9/2009 Physician Japan
Primary
Concomitant
Overdose Death 10/20/2009 83 Male 10/27/2009 Physician Italy
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 11/29/2007 57 Male 104 lb 11/17/2009 Physician Japan
Primary
Concomitant
Overdose Death 10/20/2009 83 Male 11/26/2009 Physician Italy
Primary
Concomitant
Hyperkalaemia Hospitalization 11/30/2007 Male 198 lb 11/30/2009 Physician Germany
Primary
Secondary
Concomitant
Tremor Other Serious 7/10/2009 12/14/2009 Physician Italy
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 9/22/2009 77 Male 154 lb 12/21/2009 Physician United States
Primary
Concomitant
Pain In Extremity Other Serious 11/27/2009 56 Female 200 lb 12/17/2009 Pharmacist United States
Primary
Concomitant
Pyrexia Hospitalization 11/26/2004 74 Male 12/17/2009 China
Primary
Concomitant
Respiratory Failure Hospitalization 9/22/2009 77 Male 154 lb 12/31/2009 Physician United States
Primary
Concomitant
Respiratory Failure Hospitalization 9/22/2009 77 Male 154 lb 1/5/2010 Physician United States
Primary
Concomitant
Paraesthesia Other Serious Male 178 lb 1/8/2010 Physician United States
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 1/12/2010 92 Female 175 lb 2/19/2010 Physician Germany
Primary
Concomitant
Respiratory Failure Required Intervention 2/25/2010 79 Male 222 lb 3/12/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 6/28/2007 60 Male 4/6/2010 Consumer United States
Primary
Secondary
Concomitant
Myocardial Ischaemia Other Serious Male 222 lb 5/10/2010 Other Health Professional United States
Primary
Concomitant
Myocardial Ischaemia Hospitalization 78 Male 222 lb 5/19/2010 Other Health Professional United States
Primary
Concomitant
Renal Failure Chronic Other Serious 11/19/2007 64 Male 5/24/2010 Lawyer United States
Primary
Concomitant

Drug Data