Allopurinol combined with Hydrea

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
White Blood Cell Count Decreased Hospitalization 1/15/2003 79 Male 187 lb 3/17/2006 United States
Primary
Concomitant
Pyrexia Other Serious 4/24/2006 46 Male 6/21/2006 Physician France
Primary
Concomitant
Drug Ineffective Male 163 lb 8/4/2006 Physician United States
Primary
Concomitant
Urinary Tract Infection 1/1/2004 Female 146 lb 8/8/2006 Physician United States
Primary
Concomitant
Myelodysplastic Syndrome Other Serious 6/1/2006 Female 8/14/2006 Physician United States
Primary
Concomitant
Tachypnoea Other Serious 5/17/2002 75 Female 198 lb 8/18/2006 United States
Primary
Concomitant
Red Blood Cell Count Decreased Life Threatening 1/31/2006 58 Male 9/19/2006 Japan
Primary
Concomitant
Tachycardia Hospitalization 8/24/2006 58 Male 9/26/2006 Physician United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 9/18/2006 69 Female 181 lb 10/3/2006 Physician United States
Primary
Concomitant
Tongue Disorder Other Serious 1/1/2006 Female 10/5/2006 Other Health Professional United States
Primary
Concomitant
Tongue Disorder Other Serious 1/1/2006 Female 10/31/2006 Other Health Professional United States
Primary
Concomitant
Thrombocytopenia Other Serious 83 Male 12/12/2006 Other Health Professional Korea, Republic Of
Primary
Concomitant
Weight Decreased Hospitalization 1/24/2003 67 Female 85 lb 12/6/2006 Physician Japan
Primary
Concomitant
Stomatitis Hospitalization 1/1/2002 33 Male 2/26/2007 Other Health Professional France
Primary
Concomitant
Thrombosis Other Serious 9/1/2006 89 Female 3/8/2007 Physician United States
Primary
Concomitant
Weight Increased Other Serious 9/18/2006 69 Female 181 lb 4/27/2007 Other Health Professional United States
Primary
Concomitant
Somnolence Other Serious 1/1/2003 79 Male 77 lb 5/13/2007 Physician Japan
Primary
Concomitant
Renal Failure Chronic Hospitalization 6/29/2002 78 Female 5/22/2007 Other Health Professional United States
Primary
Concomitant
White Blood Cell Count Increased Other Serious 3/1/2006 61 Female 143 lb 4/24/2007 Physician United States
Primary
Concomitant
Liver Function Test Abnormal Hospitalization 2/27/2006 28 Female 155 lb 4/24/2007 Other Health Professional United States
Primary
Concomitant
Somnolence Other Serious 1/1/2003 79 Male 77 lb 7/6/2007 Physician Japan
Primary
Concomitant
Metastasis Other Serious 6/6/2007 61 Male 9/19/2007 Physician France
Primary
Concomitant
Pancreatitis Other Serious Female 12/6/2007 Consumer Australia
Primary
Concomitant
Renal Failure Chronic Hospitalization 6/29/2002 78 Female 1/4/2008 Other Health Professional United States
Primary
Concomitant
Oedema Peripheral Other Serious 12/1/2007 Female 146 lb 1/18/2008 Other Health Professional United States
Primary
Concomitant
Oedema Peripheral Other Serious 12/1/2007 Female 146 lb 1/21/2008 Other Health Professional United States
Primary
Concomitant
Malignant Neoplasm Progression Other Serious 9/22/2007 64 Female 1/23/2008 Physician Japan
Primary
Concomitant
Splenomegaly Hospitalization 65 Male 143 lb 2/18/2008 Consumer Brazil
Primary
Concomitant
Splenomegaly Hospitalization 65 Male 143 lb 3/8/2008 Consumer Brazil
Primary
Concomitant
Vomiting Hospitalization 12/30/2007 64 Male 264 lb 3/3/2008 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 12/30/2007 64 Male 264 lb 3/7/2008 United States
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 12/30/2007 64 Male 264 lb 3/11/2008 United States
Primary
Secondary
Concomitant
Splenomegaly Hospitalization 65 Male 143 lb 3/20/2008 Consumer Brazil
Primary
Concomitant
Tachycardia Life Threatening 10/11/2007 71 Male 3/27/2008 Other Health Professional United States
Primary
Concomitant
Rash Morbilliform Hospitalization 3/3/2008 55 Male 4/23/2008 France
Primary
Secondary
Pulmonary Hypertension Life Threatening 11/16/2007 Male 4/24/2008 France
Primary
Secondary
Concomitant
Tachypnoea Life Threatening 10/11/2007 71 Male 5/23/2008 Other Health Professional United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2007 Male 183 lb 6/16/2008 Physician Canada
Primary
Concomitant
Vomiting Hospitalization 12/30/2007 64 Male 264 lb 6/17/2008 United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 12/30/2007 64 Male 264 lb 6/17/2008 United States
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 1/6/2008 75 Male 7/21/2008 Physician France
Primary
Concomitant
White Blood Cell Count Increased Other Serious 3/28/2008 Female 8/7/2008 Physician United States
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 6/11/2007 Male 174 lb 8/25/2008 Physician United States
Primary
Concomitant
Urinary Tract Infection Other Serious 6/11/2007 Male 174 lb 8/21/2008 Physician United States
Primary
Concomitant
Squamous Cell Carcinoma Other Serious 2/9/2005 80 Male 168 lb 9/15/2008 Physician United Kingdom
Primary
Concomitant
Thrombocytopenia Other Serious 5/30/2008 Female 10/1/2008 Other Health Professional United States
Primary
Concomitant
Hypokalaemia Hospitalization 12/30/2007 64 Male 264 lb 10/13/2008 United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 12/30/2007 64 Male 264 lb 10/17/2008 United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 12/30/2007 64 Male 264 lb 11/13/2008 United States
Primary
Secondary
Concomitant
Malignant Neoplasm Progression Hospitalization 12/30/2007 64 Male 264 lb 11/6/2008 United States
Primary
Secondary
Concomitant
Melaena Other Serious 12/30/2008 Male 150 lb 12/31/2008 Consumer United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization Male 150 lb 1/8/2009 Other Health Professional United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 12/30/2008 73 Male 150 lb 1/21/2009 Other Health Professional United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 12/30/2008 73 Male 150 lb 1/28/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Wheezing Other Serious 12/15/2008 Male 2/23/2009 United States
Primary
Concomitant
Skin Disorder Other Serious 10/20/2001 73 Female 3/2/2009 Physician France
Primary
Secondary
Concomitant
Cerebral Haemorrhage Other Serious 3/21/2009 Male 139 lb 4/1/2009 France
Primary
Concomitant
Cerebral Haemorrhage Other Serious 3/21/2009 Male 139 lb 4/10/2009 France
Primary
Concomitant
Melaena Hospitalization 12/30/2008 Male 150 lb 12/31/2008 Consumer United States
Primary
Secondary
Concomitant
Pleural Effusion Hospitalization 4/20/2009 73 Male 175 lb 5/5/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Cerebral Haemorrhage Other Serious 3/21/2009 Male 139 lb 5/21/2009 France
Primary
Concomitant
Sepsis Other Serious 69 Male 150 lb 5/22/2009 Physician United States
Primary
Concomitant
Pericardial Effusion Hospitalization 4/20/2009 73 Male 175 lb 5/26/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 12/30/2007 64 Male 264 lb 6/2/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 12/30/2007 64 Male 264 lb 6/2/2009 Physician United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 12/30/2007 64 Male 264 lb 6/5/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Somnolence Other Serious 4/30/2009 79 Female 6/23/2009 Physician United States
Primary
Concomitant
Rash 4/24/2009 Male 7/24/2009 Physician United States
Primary
Concomitant
Rash Other Serious 4/24/2009 Male 8/3/2009 Consumer United States
Primary
Concomitant
Rash Hospitalization 4/24/2009 Male 8/10/2009 Consumer United States
Primary
Concomitant
Leukaemia Death Female 9/3/2009 Lawyer United States
Primary
Concomitant
White Blood Cell Count Increased Other Serious 7/27/2009 Male 10/7/2009 United States
Primary
Concomitant
Rash Hospitalization 4/24/2009 Male 10/16/2009 Consumer United States
Primary
Concomitant
Pneumonia Other Serious 1/1/2007 72 Female 10/21/2009 Lawyer United States
Primary
Concomitant
Nausea Hospitalization 12/30/2007 64 Male 264 lb 11/17/2009 United States
Primary
Secondary
Concomitant
Pneumonia Other Serious 1/1/2007 72 Female 1/27/2010 Lawyer United States
Primary
Concomitant
Ulcer Hospitalization 8/1/2008 Female 110 lb 2/3/2010 Belgium
Primary
Concomitant
Leukocytosis Death 2/1/2010 Male 137 lb 3/1/2010 United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 8/14/2004 70 Female 4/12/2010 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 10/1/2009 76 Male 4/13/2010 Physician Japan
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 1/14/2010 57 Female 4/26/2010 Physician France
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 4/27/2010 53 Female 203 lb 6/10/2010 Physician Netherlands
Primary
Secondary
Concomitant
Serum Ferritin Increased Hospitalization 5/15/2010 58 Male 6/16/2010 Physician France
Primary
Secondary
Concomitant
Renal Failure Acute Life Threatening Female 7/9/2010 United States
Primary
Concomitant
Headache 5/1/2009 50 Male 247 lb 7/26/2010 Consumer United States
Primary
Concomitant
Visceral Arterial Ischaemia Other Serious 2/1/2010 62 Male 171 lb 8/10/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Respiratory Failure Life Threatening 4/27/2010 53 Female 203 lb 8/27/2010 Physician Netherlands
Primary
Secondary
Concomitant
Acute Myeloid Leukaemia Hospitalization 8/23/2010 74 Male 9/3/2010 Physician United States
Primary
Concomitant
Acute Myeloid Leukaemia Hospitalization 8/23/2010 74 Male 9/9/2010 Physician United States
Primary
Concomitant
Interstitial Lung Disease Hospitalization 10/16/2009 75 Male 9/23/2010 Physician France
Primary
Secondary
Interstitial Lung Disease Hospitalization 75 Male 9/29/2010 Physician France
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 10/1/2009 76 Male 10/29/2010 Physician Japan
Primary
Secondary
Concomitant
Pulmonary Alveolar Haemorrhage Death 6/5/2010 79 Male 121 lb 11/19/2010 Physician Japan
Primary
Concomitant
Serum Ferritin Increased Hospitalization 5/15/2010 58 Male 12/24/2010 Physician France
Primary
Secondary
Concomitant
Skin Disorder Other Serious 10/20/2001 73 Female 12/30/2010 Physician France
Primary
Secondary
Concomitant
Vision Blurred Other Serious 9/1/2010 28 Male 171 lb 1/4/2011 Consumer United States
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 55 Male 2/1/2011 Other Health Professional Sweden
Primary
Secondary
Concomitant
Tumour Lysis Syndrome Hospitalization 1/8/2011 73 Male 148 lb 2/7/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Pulmonary Alveolar Haemorrhage Death 6/5/2010 79 Male 121 lb 2/17/2011 Physician Japan
Primary
Concomitant
Venous Thrombosis Limb Hospitalization 10/1/2010 77 Male 3/24/2011 Consumer France
Primary
Secondary
Pyrexia Other Serious 10/1/2010 77 Male 3/29/2011 Physician France
Primary
Secondary
Gout Other Serious 2/1/2011 77 Male 3/30/2011 Other Health Professional France
Primary
Secondary
Concomitant
Haemoglobin Decreased Hospitalization 4/1/2010 83 Male 3/31/2011 Other Health Professional France
Primary
Concomitant
Dyspnoea Other Serious 1/10/2011 78 Male 247 lb 4/5/2011 Physician United States
Primary
Concomitant
Disturbance In Attention Hospitalization 5/20/2010 75 Male 4/6/2011 Other Health Professional France
Primary
Secondary
Concomitant
Hypermagnesaemia Hospitalization 3/31/2011 57 Male 173 lb 4/15/2011 United States
Primary
Concomitant
Myalgia Life Threatening 5/1/2009 65 Female 4/29/2011 Physician Japan
Primary
Secondary
Concomitant
Chronic Myeloid Leukaemia Transformation Death 5/1/2009 65 Female 5/6/2011 Physician Japan
Primary
Secondary
Concomitant
Fall Hospitalization 3/15/2011 75 Female 5/12/2011 Consumer Canada
Primary
Concomitant
Splenomegaly Hospitalization 4/16/2011 76 Male 163 lb 5/17/2011 Other Health Professional United States
Primary
Concomitant
Platelet Count Decreased Hospitalization 4/16/2011 76 Male 163 lb 6/2/2011 Other Health Professional United States
Primary
Concomitant
Abdominal Pain Other Serious 12/15/2008 73 Male 6/11/2011 Consumer United States
Primary
Concomitant
Respiratory Failure Life Threatening 4/27/2010 53 Female 203 lb 6/29/2011 Physician Netherlands
Primary
Secondary
Concomitant
Hyperuricaemia Hospitalization 2/14/2009 68 Male 7/13/2011 Physician Japan
Primary
Secondary
Concomitant
Cholestasis Hospitalization 6/17/2011 77 Male 8/9/2011 Physician France
Primary
Secondary
Cerebral Thrombosis Life Threatening 58 Male 205 lb 8/8/2011 Lawyer United States
Primary
Concomitant
Hypermagnesaemia Hospitalization 3/31/2011 57 Male 186 lb 8/30/2011 Consumer United States
Primary
Concomitant
Haemorrhage Death 3/4/2010 63 Female 116 lb 10/5/2011 Other Health Professional United States
Primary
Concomitant
Hyperglycaemia Life Threatening 10/3/2011 Male 10/13/2011 Physician Japan
Primary
Concomitant
Death Death 10/3/2011 Male 10/18/2011 Physician Japan
Primary
Concomitant
Acute Myeloid Leukaemia Hospitalization 8/10/2011 83 Female 205 lb 10/19/2011 Physician United States
Primary
Concomitant
Pain Male 10/31/2011 Consumer United States
Primary
Concomitant
Blood Uric Acid Increased Other Serious Male 128 lb 11/1/2011 Other Health Professional Japan
Primary
Concomitant
Scan Adrenal Gland Abnormal Other Serious 3/4/2010 63 Female 116 lb 11/1/2011 Physician United States
Primary
Concomitant
Metabolic Acidosis Other Serious 10/4/2011 43 Male 11/3/2011 Physician Japan
Primary
Concomitant
Myelodysplastic Syndrome Other Serious 8/7/2010 64 Male 143 lb 11/4/2011 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 8/7/2010 64 Male 143 lb 11/4/2011 Physician Japan
Primary
Secondary
Concomitant
Fatigue Other Serious 3/4/2010 63 Female 116 lb 11/8/2011 Physician United States
Primary
Concomitant
Tumour Lysis Syndrome Other Serious 10/4/2011 43 Male 12/1/2011 Physician Japan
Primary
Concomitant
Blast Cell Count Increased Other Serious 11/15/2010 51 Male 12/6/2011 Physician Japan
Primary
Concomitant
Abdominal Pain Upper Other Serious 10/4/2011 43 Male 12/28/2011 Physician Japan
Primary
Concomitant
Platelet Count Increased Death 8/7/2010 64 Male 143 lb 12/31/2011 Physician Japan
Primary
Secondary
Concomitant
Asthenia Hospitalization 1/1/2010 65 Female 1/5/2012 Other Health Professional France
Primary
Secondary
Concomitant
Pyrexia Hospitalization 3/15/2011 75 Female 1/9/2012 Canada
Primary
Concomitant
Abdominal Pain Upper Death 10/4/2011 43 Male 1/17/2012 Physician Japan
Primary
Concomitant
Blood Alkaline Phosphatase Increased Other Serious 12/21/2010 83 Male 11/6/2011 Physician United States
Primary
Concomitant
Pain Hospitalization 2/26/2007 44 Male 138 lb 11/6/2011 Other Health Professional United States
Primary
Concomitant
Blast Cell Count Increased Hospitalization 11/15/2010 51 Male 1/26/2012 Physician Japan
Primary
Concomitant
Haematotoxicity Other Serious 5/17/2011 57 Female 1/30/2012 Tunisia
Primary
Secondary
Concomitant
Fall Hospitalization 3/15/2011 75 Female 1/31/2012 Consumer Canada
Primary
Concomitant
Polyarthritis Hospitalization 1/6/2012 56 Male 1/29/2012 Consumer Japan
Primary
Concomitant
Feeling Abnormal Other Serious 3/15/2011 75 Female 2/6/2012 Canada
Primary
Concomitant
Dyspnoea Hospitalization 2/6/2012 80 Female 2/10/2012 Consumer Ireland
Primary
Concomitant
Joint Swelling Other Serious 3/15/2011 75 Female 2/20/2012 Canada
Primary
Concomitant
Dyspnoea Hospitalization 10/20/2001 75 Female 2/22/2012 Physician France
Primary
Secondary
Concomitant
Coronary Artery Occlusion Hospitalization 3/15/2011 75 Female 2/29/2012 Physician Canada
Primary
Concomitant
Fluid Retention Other Serious 58 Female 5/28/2010 Consumer United States
Primary
Concomitant
Urine Output Decreased Life Threatening 10/4/2011 43 Male 4/11/2012 Other Health Professional Japan
Primary
Concomitant
Myelodysplastic Syndrome Transformation Death 9/1/2011 76 Male 154 lb 4/11/2012 Physician United States
Primary
Concomitant
Eye Swelling Other Serious 11/2/2009 37 Female 109 lb 5/28/2010 Other Health Professional United States
Primary
Secondary
Concomitant

Drug Data