Allopurinol combined with Heparin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
White Blood Cell Count Decreased Hospitalization 11/9/2005 64 Male 171 lb 1/5/2006 United States
Primary
Secondary
Concomitant
Rash Macular Other Serious 9/4/2005 77 Female 194 lb 1/17/2006 Other Health Professional United States
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 11/1/2004 75 Female 130 lb 1/24/2006 Other Health Professional Australia
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 1/14/2006 54 Male 214 lb 1/25/2006 Physician Netherlands
Primary
Secondary
Concomitant
Skin Toxicity Other Serious 1/13/2006 32 Female 183 lb 1/25/2006 Physician Netherlands
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 11/1/2004 75 Female 130 lb 1/24/2006 Other Health Professional Australia
Primary
Secondary
Concomitant
Thrombophlebitis Hospitalization 5/14/2005 33 Male 2/7/2006 Physician United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 1/13/2006 32 Female 183 lb 2/1/2006 Physician Netherlands
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 1/14/2006 54 Male 214 lb 2/1/2006 Physician Netherlands
Primary
Secondary
Concomitant
Thrombophlebitis Hospitalization 5/14/2005 33 Male 2/10/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Therapy Non-responder Other Serious 1/13/2006 32 Female 183 lb 2/9/2006 Physician Netherlands
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 1/14/2006 54 Male 214 lb 2/10/2006 Physician Netherlands
Primary
Secondary
Concomitant
Respiratory Distress Life Threatening 8/19/2005 66 Male 3/1/2006 Physician Switzerland
Primary
Secondary
Concomitant
Ventricular Hypertrophy Other Serious 7/3/2005 Female 195 lb 3/3/2006 Physician United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 1/14/2006 54 Male 214 lb 2/23/2006 Physician Netherlands
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 1/13/2006 32 Female 190 lb 2/23/2006 Physician Netherlands
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 1/13/2006 32 Female 183 lb 3/1/2006 Physician Netherlands
Primary
Secondary
Concomitant
Sudden Cardiac Death Other Serious 1/14/2006 54 Male 214 lb 3/1/2006 Physician Netherlands
Primary
Secondary
Concomitant
Weight Increased Hospitalization 9/17/2003 60 Male 287 lb 3/14/2006 United States
Primary
Concomitant
Sudden Cardiac Death Other Serious 1/14/2006 54 Male 214 lb 3/8/2006 Physician Netherlands
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 1/13/2006 32 Female 168 lb 3/8/2006 Physician Netherlands
Primary
Secondary
Concomitant
Weight Increased Hospitalization 5/22/2003 72 Female 121 lb 3/17/2006 United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 1/14/2006 54 Male 214 lb 3/21/2006 Physician Netherlands
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 1/13/2006 32 Female 168 lb 3/21/2006 Physician Netherlands
Primary
Secondary
Concomitant
White Blood Cell Count Abnormal Other Serious 2/24/2006 Female 4/13/2006 Physician United States
Primary
Concomitant
Cystitis Haemorrhagic Hospitalization 4/27/2005 61 Male 4/18/2006 Consumer United States
Primary
Concomitant
Shunt Occlusion Other Serious 12/21/2005 56 Male 4/10/2006 Physician Japan
Primary
Concomitant
Ventricular Tachycardia Death 1/18/2002 44 Male 311 lb 4/26/2006 Lawyer United States
Primary
Concomitant
Renal Failure Hospitalization 1/10/2006 63 Male 5/5/2006 United States
Primary
Concomitant
Weight Increased Hospitalization 5/22/2003 72 Female 121 lb 5/3/2006 United States
Primary
Concomitant
Somnolence Hospitalization 2/14/2006 60 Male 5/11/2006 France
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 3/21/2006 76 Male 150 lb 6/7/2006 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 3/21/2006 76 Male 150 lb 6/16/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Failure Acute Required Intervention 2/2/2005 74 Male 319 lb 5/24/2006 Other Health Professional United States
Primary
Concomitant
Renal Impairment Disability 4/7/2006 77 Male 128 lb 7/21/2006 Physician Japan
Primary
Concomitant
Thrombocytopenia Other Serious 80 Female 130 lb 5/9/2005 Pharmacist United States
Primary
Secondary
Concomitant
Sudden Death Death 3/8/2005 56 Male 7/20/2006 Physician United States
Primary
Concomitant
Thrombocytopenia Required Intervention 10/13/2005 55 Male 6/9/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 6/4/2006 59 Male 7/21/2006 Pharmacist United States
Primary
Concomitant
Sudden Death Death 3/8/2005 56 Male 303 lb 8/8/2006 Physician United States
Primary
Concomitant
Pulmonary Oedema Hospitalization 3/11/2006 70 Male 204 lb 6/9/2006 Pharmacist United States
Primary
Concomitant
Haemoglobin Decreased Life Threatening 3/24/2005 49 Male 196 lb 9/27/2006 Pharmacist United States
Primary
Concomitant
Therapy Non-responder Hospitalization 59 Female 143 lb 9/25/2006 Physician United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 4/22/2003 55 Male 280 lb 9/26/2006 United States
Primary
Concomitant
Serotonin Syndrome Other Serious 9/23/2006 38 Female 225 lb 9/28/2006 Pharmacist United States
Primary
Concomitant
Coronary Artery Dissection Other Serious 9/12/2006 Male 256 lb 10/5/2006 Physician Belgium
Primary
Concomitant
Weight Increased Other Serious 8/1/2006 Male 152 lb 10/12/2006 Physician Spain
Primary
Secondary
Concomitant
Tachycardia 5/2/2006 51 Male 10/24/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Loss Of Consciousness Hospitalization 6/29/2005 63 Male 10/25/2006 Physician Japan
Primary
Concomitant
Vomiting 2/8/2006 36 Male Physician United States
Primary
Concomitant
Shock Death 4/21/2006 73 Male 221 lb 10/30/2006 Pharmacist United States
Primary
Concomitant
Serotonin Syndrome Other Serious 9/23/2006 38 Female 11/3/2006 Physician United States
Primary
Concomitant
Renal Impairment Disability 4/7/2006 77 Male 128 lb 11/20/2006 Physician Japan
Primary
Concomitant
Staphylococcal Infection Other Serious 9/23/2006 38 Female 219 lb 11/30/2006 Physician United States
Primary
Concomitant
Neutropenia Other Serious 7/1/2006 73 Male 165 lb 1/26/2007 Physician France
Primary
Concomitant
Ventricular Dysfunction Other Serious 2/26/2007 Male 173 lb 4/11/2007 Physician United States
Primary
Concomitant
Tachypnoea Hospitalization 3/20/2007 Male 4/6/2007 United States
Primary
Concomitant
Respiratory Arrest Life Threatening 3/27/2007 62 Male 260 lb 5/9/2007 Consumer United States
Primary
Concomitant
Viral Infection Hospitalization 11/2/2006 58 Male 268 lb 5/10/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Pruritus Hospitalization 1/1/2006 75 Male 235 lb 5/21/2007 Consumer United States
Primary
Concomitant
White Blood Cell Count Decreased Life Threatening 4/9/2007 19 Male 164 lb 5/24/2007 Physician United States
Primary
Secondary
Concomitant
Ventricular Tachycardia Life Threatening 4/9/2007 19 Male 167 lb 6/4/2007 Physician United States
Primary
Secondary
Concomitant
Thrombocytopenic Purpura Other Serious 1/1/2007 79 Female 146 lb 6/5/2007 Pharmacist United States
Primary
Concomitant
White Blood Cell Count Decreased Life Threatening 4/9/2007 19 Male 167 lb 6/7/2007 Physician United States
Primary
Secondary
Concomitant
Liver Disorder Hospitalization 6/16/2007 82 Female 7/13/2007 Consumer France
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 7/4/2007 Male 168 lb 7/13/2007 Consumer Australia
Primary
Secondary
Concomitant
Hepatic Failure Other Serious 6/1/2007 Female 7/26/2007 Other Health Professional France
Primary
Secondary
Concomitant
Trichorrhexis 1/1/2006 Female 7/26/2007 Consumer United States
Primary
Concomitant
Hyperkalaemia Hospitalization 3/21/2006 76 Male 150 lb 8/16/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Interacting
Death Death 5/1/2007 Male 183 lb 9/5/2007 United States
Primary
Concomitant
Haemorrhage Hospitalization 7/29/2007 Male 204 lb 9/11/2007 Physician United States
Primary
Secondary
Concomitant
Death Death 5/1/2007 Male 183 lb 9/11/2007 United States
Primary
Concomitant
Thrombocytopenia Life Threatening 1/1/2007 86 Male 128 lb 9/17/2007 Japan
Primary
Secondary
Concomitant
Haemorrhage Hospitalization 7/29/2007 Male 204 lb 9/19/2007 Physician United States
Primary
Secondary
Concomitant
Upper Gastrointestinal Haemorrhage Hospitalization 6/21/2007 Male 142 lb 9/21/2007 Other Health Professional United States
Primary
Concomitant
Subarachnoid Haemorrhage Hospitalization 7/29/2007 Male 204 lb 10/11/2007 Physician United States
Primary
Secondary
Concomitant
Unresponsive To Stimuli Hospitalization 1/6/2007 60 Male 10/12/2007 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 4/1/2006 67 Male 10/19/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 8/1/2005 Male 170 lb 10/26/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Multiple Myeloma Hospitalization 5/4/2006 67 Male 172 lb 10/29/2007 Physician United States
Primary
Secondary
Concomitant
Osteonecrosis Hospitalization 12/21/2006 60 Male 10/29/2007 United States
Primary
Secondary
Concomitant
Death Death 5/23/2007 Male 183 lb 11/2/2007 United States
Primary
Concomitant
Myoclonus Other Serious 10/24/2007 Male 536 lb 11/2/2007 Physician United States
Primary
Concomitant
Staphylococcal Bacteraemia Life Threatening 10/7/2007 14 Male 203 lb 11/8/2007 Physician United States
Primary
Secondary
Concomitant
Multiple Myeloma Hospitalization 5/4/2006 67 Male 11/9/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Uraemic Encephalopathy Hospitalization 4/10/2007 83 Female 12/18/2007 Other Health Professional France
Primary
Concomitant
Stevens-johnson Syndrome Hospitalization 8/4/2003 Female 1/25/2008 Physician Germany
Primary
Secondary
Concomitant
Renal Impairment Life Threatening 12/22/2007 64 Male 128 lb 1/28/2008 Physician Japan
Primary
Secondary
Concomitant
Musculoskeletal Pain Required Intervention 1/19/2008 59 Male 1/28/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Death Death 5/23/2007 Male 183 lb 2/5/2008 United States
Primary
Concomitant
Toxic Epidermal Necrolysis Life Threatening 1/31/2005 69 Male 2/13/2008 Physician Germany
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 11/14/2006 58 Male 269 lb 2/18/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Stevens-johnson Syndrome Hospitalization 6/7/2003 81 Female 2/14/2008 Physician Germany
Primary
Secondary
Toxic Epidermal Necrolysis Life Threatening 3/7/2003 70 Female 2/25/2008 Other Health Professional Germany
Primary
Secondary
Concomitant
Agranulocytosis Hospitalization 8/31/2007 Male 2/25/2008 Other Health Professional Germany
Primary
Secondary
Concomitant
Stevens-johnson Syndrome Hospitalization 6/7/2003 81 Female 2/14/2008 Physician Germany
Primary
Secondary
Stevens-johnson Syndrome Death 7/22/2005 81 Female 2/25/2008 Germany
Primary
Secondary
Concomitant
Stevens-johnson Syndrome Death 7/22/2005 Female 2/28/2008 Physician Germany
Primary
Secondary
Stevens-johnson Syndrome Hospitalization 8/4/2003 68 Female 3/4/2008 Other Health Professional Germany
Primary
Secondary
Concomitant
Tricuspid Valve Incompetence Hospitalization 9/14/2007 73 Male 153 lb 3/20/2008 Physician United States
Primary
Concomitant
Aspergillosis Death 1/20/2008 Male 4/2/2008 Physician France
Primary
Secondary
Concomitant
Cerebral Haemorrhage Hospitalization 7/29/2007 Male 204 lb 4/4/2008 Physician United States
Primary
Secondary
Concomitant
Meningeal Disorder Hospitalization 7/4/2007 Male 168 lb 4/14/2008 Consumer Australia
Primary
Secondary
Concomitant
Cholangitis Hospitalization 2/15/2008 26 Male 4/17/2008 Consumer United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 6/21/2007 81 Male 142 lb 5/2/2008 Other Health Professional United States
Primary
Concomitant
Urinary Tract Infection Staphylococcal Hospitalization 6/21/2007 81 Male 142 lb 5/21/2008 Other Health Professional United States
Primary
Concomitant
Vomiting 12/1/2007 70 Female 226 lb 6/3/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Death Death 5/23/2007 Male 183 lb 6/18/2008 United States
Primary
Concomitant
Urinary Tract Infection Bacterial Hospitalization 6/21/2007 81 Male 142 lb 6/26/2008 Other Health Professional United States
Primary
Concomitant
Cytolytic Hepatitis Other Serious 30 Male 7/14/2008 Physician France
Primary
Secondary
Concomitant
Vomiting Hospitalization 5/20/2008 78 Male 7/31/2008 United States
Primary
Secondary
Concomitant
Jaundice Hospitalization 7/21/2008 52 Male 278 lb 8/11/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 5/20/2008 78 Male 216 lb 8/11/2008 United States
Primary
Secondary
Concomitant
Tricuspid Valve Incompetence Hospitalization 9/14/2007 73 Male 153 lb 8/14/2008 Physician United States
Primary
Concomitant
Respiratory Failure Hospitalization 11/14/2006 58 Male 269 lb 9/2/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 5/20/2008 78 Male 216 lb 8/22/2008 United States
Primary
Secondary
Concomitant
Somnolence Required Intervention 5/23/2008 87 Female 8/19/2008 Pharmacist United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 8/13/2008 45 Male 170 lb 9/22/2008 Physician Germany
Primary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 7/19/2008 Male 185 lb 9/26/2008 United States
Primary
Concomitant
Hypotension Other Serious 7/30/2008 71 Male 134 lb 9/30/2008 Physician United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 8/13/2008 45 Male 170 lb 10/8/2008 Germany
Primary
Concomitant
Thrombocytopenia Other Serious 8/19/2008 Female 130 lb 10/15/2008 Physician Poland
Primary
Secondary
Concomitant
Myelodysplastic Syndrome Other Serious 9/6/2008 Male 10/17/2008 Other Health Professional United States
Primary
Concomitant
Hypotension Hospitalization 9/28/2008 67 Female 10/17/2008 Other Health Professional United States
Primary
Concomitant
Haemorrhage Life Threatening 10/30/2007 Male 157 lb 11/3/2008 Physician Canada
Primary
Concomitant
Hyperkalaemia Hospitalization 3/21/2006 76 Male 150 lb 11/6/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Myelodysplastic Syndrome Other Serious 9/6/2008 Male 11/6/2008 Other Health Professional United States
Primary
Concomitant
Therapeutic Response Decreased Other Serious 1/1/2008 Male 11/11/2008 Pharmacist United States
Primary
Concomitant
Convulsion Hospitalization 10/15/2008 Female 11/13/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Epistaxis Hospitalization Male 11/21/2008 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Required Intervention 4/12/2007 19 Male 165 lb 11/18/2008 Physician United States
Primary
Secondary
Concomitant
Myelodysplastic Syndrome Other Serious 9/6/2008 Male 12/4/2008 Other Health Professional United States
Primary
Concomitant
Convulsion Hospitalization 10/15/2008 Female 12/10/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Vomiting Other Serious 12/1/2007 70 Female 225 lb 1/30/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Somnolence Life Threatening 12/30/2007 Male 214 lb 2/5/2009 Australia
Primary
Secondary
Concomitant
Arterial Haemorrhage Life Threatening 10/30/2007 Male 157 lb 2/6/2009 Physician Canada
Primary
Concomitant
Vasodilatation 12/26/2008 61 Male 2/20/2009 Japan
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 10/1/2008 Female 116 lb 3/3/2009 United States
Primary
Secondary
Concomitant
Muscle Spasms 5/23/2008 Male 279 lb 3/18/2009 Other Health Professional United States
Primary
Concomitant
Somnolence Other Serious 12/30/2007 Male 214 lb 3/25/2009 Australia
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 10/1/2008 57 Female 116 lb 3/26/2009 United States
Primary
Secondary
Concomitant
Meningitis Hospitalization 5/20/2006 53 Female 5/19/2009 United States
Primary
Concomitant
Pneumonia Primary Atypical Hospitalization 4/7/2009 36 6/8/2009 Physician Germany
Primary
Secondary
Concomitant
Swollen Tongue Other Serious 8/13/2008 Male 170 lb 6/9/2009 Germany
Primary
Secondary
Concomitant
Serum Sickness Other Serious 4/30/2007 24 Female 194 lb 5/28/2009 Physician United States
Primary
Concomitant
Pneumonia Primary Atypical Hospitalization 4/7/2009 36 6/11/2009 Physician Germany
Primary
Secondary
Concomitant
Mental Status Changes Required Intervention 5/18/2009 73 Female 126 lb 5/18/2009 United States
Primary
Concomitant
Pneumonia Primary Atypical Other Serious 4/7/2009 36 7/15/2009 Physician Germany
Primary
Secondary
Concomitant
Cardiac Failure Congestive Life Threatening 5/11/2009 Male 203 lb 7/15/2009 Canada
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 7/24/2009 50 Male 160 lb 7/24/2009 Other Health Professional United States
Primary
Secondary
Concomitant

Drug Data