Allopurinol combined with Glucophage

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Shock Death 7/15/2001 Male 1/4/2006 France
Primary
Concomitant
Surgery Hospitalization 1/1/2001 58 Male 240 lb 1/23/2006 Physician United States
Primary
Concomitant
White Blood Cell Count Increased Other Serious 6/6/2001 68 Male 1/27/2006 Physician United States
Primary
Concomitant
Weight Decreased 1/1/2005 60 Male 198 lb 1/30/2006 Consumer United States
Primary
Concomitant
Diarrhoea 74 Male 201 lb 1/30/2006 Consumer United States
Primary
Concomitant
Brain Neoplasm Malignant Death 1/1/2006 Female 236 lb 2/14/2006 Physician United States
Primary
Concomitant
Renal Failure Other Serious 7/7/2000 59 Male 260 lb 2/16/2006 Physician United States
Primary
Concomitant
Somnolence Other Serious 10/10/2005 78 Male 155 lb 1/20/2006 United States
Primary
Concomitant
Skin Chapped Other Serious 1/29/2006 52 Male 2/22/2006 United States
Primary
Concomitant
Red Blood Cell Sedimentation Rate Increased Other Serious 11/12/2005 74 Male 2/24/2006 France
Primary
Secondary
Concomitant
Venous Insufficiency Other Serious 1/1/2001 62 Male 276 lb 3/30/2006 Physician United States
Primary
Concomitant
Nausea 11/1/2005 71 Female 279 lb 1/20/2006 Consumer United States
Primary
Concomitant
Pharyngolaryngeal Pain 9/1/2005 64 Male 324 lb 1/20/2006 Consumer United States
Primary
Concomitant
Wound Infection Pseudomonas Hospitalization 5/1/2000 72 Female 231 lb 4/7/2006 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2004 Female 325 lb 4/11/2006 Consumer United States
Primary
Concomitant
Cerebrovascular Accident Hospitalization 4/21/2004 58 Male 238 lb 4/13/2006 Lawyer United States
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 10/7/2001 72 Male 172 lb 4/18/2006 Lawyer United States
Primary
Concomitant
Rash Other Serious 1/29/2006 52 Male 4/10/2006 United States
Primary
Concomitant
Rash Other Serious 1/29/2006 52 Male 4/10/2006 United States
Primary
Concomitant
White Blood Cell Count Increased Other Serious 6/6/2001 68 Male 4/21/2006 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2006 72 Male 170 lb 4/20/2006 United States
Primary
Concomitant
Weight Decreased Hospitalization 2/10/2006 80 Male 159 lb 4/20/2006 France
Primary
Secondary
Concomitant
Ureteric Injury Hospitalization 6/6/2001 67 Male 231 lb 5/1/2006 Physician United States
Primary
Concomitant
Fatigue Hospitalization 4/21/2004 58 Male 238 lb 5/1/2006 Physician United States
Primary
Concomitant
Myocardial Infarction Hospitalization 10/1/2001 71 Female 205 lb 5/2/2006 Lawyer United States
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 1/1/2001 72 Male 172 lb 5/5/2006 Physician United States
Primary
Concomitant
Dyspnoea 8/30/2005 69 Male 2/21/2006 United States
Primary
Concomitant
Ventricular Hypertrophy Hospitalization 2/9/2002 69 Male 240 lb 5/11/2006 Physician United States
Primary
Concomitant
Phlebitis Deep Other Serious 5/4/2006 72 Female 5/15/2006 Pharmacist France
Primary
Concomitant
Skin Infection Hospitalization 1/10/2006 77 Female 154 lb 5/17/2006 Physician France
Primary
Concomitant
Non-hodgkin's Lymphoma Other Serious 10/1/2003 Female 294 lb 6/15/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Skin Exfoliation Other Serious 1/29/2006 52 Male 6/21/2006 United States
Primary
Concomitant
Sinusitis Hospitalization 2/14/2006 73 Female 143 lb 6/23/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Nausea Disability 2/14/2006 59 Male 7/12/2006 Physician United States
Primary
Concomitant
Renal Failure Acute Hospitalization 7/29/2006 Male 259 lb 8/21/2006 Other Health Professional United States
Primary
Concomitant
Renal Failure Acute Hospitalization 7/29/2006 Male 259 lb 8/29/2006 Other Health Professional United States
Primary
Concomitant
Myopathy Disability 1/1/2006 59 Male 9/14/2006 Pharmacist United States
Primary
Concomitant
Weight Decreased 4/1/2006 55 Female 270 lb 7/19/2006 Consumer United States
Primary
Concomitant
Cardiac Arrest Death 9/13/2006 53 Female 353 lb 9/21/2006 Physician Germany
Primary
Concomitant
Weight Increased Other Serious 1/1/2004 Male 230 lb 10/3/2006 Physician United States
Primary
Secondary
Concomitant
Pancytopenia Other Serious 1/5/2006 70 Male 183 lb 10/3/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/2004 Male 230 lb 10/5/2006 Physician United States
Primary
Secondary
Concomitant
Respiratory Arrest Death 9/13/2006 53 Female 353 lb 10/18/2006 Physician Germany
Primary
Concomitant
Rhabdomyolysis Other Serious 4/10/2006 74 Male 10/16/2006 Pharmacist United States
Primary
Secondary
Concomitant
Drug Ineffective 1/1/2005 Male 8/22/2006 United States
Primary
Concomitant
Polymyositis Other Serious 1/30/2006 69 Male 165 lb 10/26/2006 Physician France
Primary
Secondary
Concomitant
Respiratory Arrest Death 9/13/2006 53 Female 353 lb 10/26/2006 Physician Germany
Primary
Concomitant
Vitamin B12 Decreased Other Serious 5/6/2006 79 Female 194 lb 10/31/2006 France
Primary
Secondary
Concomitant
Oesophageal Candidiasis Other Serious 1/30/2006 69 Male 165 lb 11/1/2006 Physician France
Primary
Secondary
Concomitant
Renal Failure Hospitalization 10/11/2006 62 Male 419 lb 12/13/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Photosensitivity Reaction Hospitalization 10/13/2006 78 Female 12/13/2006 Other Health Professional France
Primary
Secondary
Concomitant
Meningitis Viral Other Serious 12/7/2006 49 Male 12/26/2006 Physician United States
Primary
Concomitant
Pruritus Hospitalization 10/13/2006 78 Female 12/19/2006 France
Primary
Secondary
Concomitant
Scotoma Hospitalization 9/28/2006 67 Male 1/2/2007 Austria
Primary
Concomitant
Vomiting Hospitalization 11/16/2006 60 Male 2/7/2007 Other Health Professional France
Primary
Secondary
Concomitant
Vomiting Hospitalization 11/16/2006 60 Male 2/9/2007 Other Health Professional France
Primary
Secondary
Concomitant
Vomiting Hospitalization 11/16/2006 60 Male 2/16/2007 Other Health Professional France
Primary
Secondary
Concomitant
Hypoglycaemia Hospitalization 1/19/2007 66 Male 3/1/2007 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Blood Creatinine Increased Hospitalization 1/10/2007 72 Male 3/9/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Shock Hospitalization 2/26/2007 67 Male 3/28/2007 Other Health Professional France
Primary
Concomitant
Paraesthesia 2/1/2005 56 Male 315 lb 12/17/2006 Physician United States
Primary
Concomitant
Wound Secretion Other Serious 3/21/2007 55 Male 212 lb 3/27/2007 Other Health Professional United States
Primary
Concomitant
Injection Site Pain 11/1/2006 61 Male 245 lb 1/12/2007 Consumer United States
Primary
Concomitant
Vomiting Hospitalization 1/1/2005 80 Female 4/11/2007 Sweden
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 3/7/2007 Male 282 lb 4/16/2007 United States
Primary
Secondary
Concomitant
Shock Hospitalization 2/26/2007 67 Male 4/20/2007 Other Health Professional France
Primary
Concomitant
Haematochezia Other Serious 3/1/2007 50 Male 4/26/2007 Physician Belgium
Primary
Concomitant
Weight Decreased Other Serious 4/11/2007 46 Male 421 lb 5/5/2007 Physician United States
Primary
Concomitant
Dizziness 12/1/2006 63 Male 2/16/2007 United States
Primary
Concomitant
Urinary Retention Hospitalization 5/1/2007 60 Male 204 lb 5/11/2007 Physician Germany
Primary
Concomitant
Hypoglycaemia Hospitalization 2/15/2007 76 Male 5/31/2007 Other Health Professional Germany
Primary
Concomitant
Interacting
Macular Oedema Other Serious 74 Female 6/11/2007 Consumer Canada
Primary
Concomitant
Urinary Retention Hospitalization 5/1/2007 60 Male 204 lb 6/6/2007 Other Health Professional Germany
Primary
Concomitant
Renal Failure Acute Required Intervention 1/15/2007 72 Female 254 lb 6/12/2007 Pharmacist United States
Primary
Concomitant
Rash Vesicular Hospitalization 4/17/2007 77 Male 165 lb 7/16/2007 Consumer France
Primary
Secondary
Concomitant
Urinary Retention Hospitalization 5/1/2007 60 Male 204 lb 7/13/2007 Other Health Professional Germany
Primary
Concomitant
Cardiomegaly Male 7/23/2007 Consumer United States
Primary
Concomitant
Septic Shock Hospitalization 66 Male 7/24/2007 Other Health Professional Germany
Primary
Secondary
Septic Shock Death 66 Male 7/30/2007
Primary
Secondary
Concomitant
Acute Febrile Neutrophilic Dermatosis Hospitalization 4/17/2007 77 Male 8/1/2007
Primary
Secondary
Concomitant
Urinary Retention Hospitalization 5/1/2007 60 Male 204 lb 7/13/2007 Other Health Professional Germany
Primary
Concomitant
Septic Shock Death 66 Male 7/20/2007 France
Primary
Secondary
Thrombocytopenia Hospitalization 7/22/2007 62 Female 180 lb 8/8/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Skin Bacterial Infection Other Serious 5/4/2006 72 Female 8/13/2007 Pharmacist France
Primary
Concomitant
Urinary Retention Hospitalization 5/1/2007 60 Male 204 lb 8/10/2007 Other Health Professional Germany
Primary
Concomitant
Lactic Acidosis Hospitalization 11/16/2006 60 Male 8/22/2007 Other Health Professional France
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 11/16/2006 60 Male 8/22/2007 Other Health Professional France
Primary
Secondary
Concomitant
Weight Increased 2/1/2007 56 Male 297 lb 7/11/2007 Consumer United States
Primary
Concomitant
Respiratory Disorder Hospitalization 6/1/2007 79 Male 8/28/2007 France
Primary
Secondary
Concomitant
Septic Shock Death 66 Male 9/4/2007
Primary
Secondary
Concomitant
Pancreatic Disorder Life Threatening 83 Male 216 lb 9/24/2007 Physician United States
Primary
Secondary
Concomitant
Vertigo Disability 5/14/2007 Male 10/11/2007 Physician France
Primary
Concomitant
Swelling Face Other Serious 1/1/2007 72 Female 230 lb 10/24/2007 Physician United States
Primary
Concomitant
Swelling Face Other Serious 1/1/2007 72 Female 230 lb 10/24/2007 Physician United States
Primary
Concomitant
Haematoma Infection Other Serious 10/22/2007 66 Male 11/12/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 12/12/2006 75 Female 190 lb 11/12/2007 Physician France
Primary
Concomitant
Urinary Retention Hospitalization 5/1/2007 60 Male 204 lb 11/12/2007 Germany
Primary
Concomitant
Haematochezia Other Serious 6/1/2007 Female 270 lb 1/14/2008 Physician United States
Primary
Concomitant
Pallor Hospitalization 7/8/2007 74 Female 1/22/2008 France
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 5/17/2007 75 Female 230 lb 1/18/2008 Physician United States
Primary
Concomitant
Impaired Gastric Emptying 72 Female 2/1/2008 Consumer United States
Primary
Concomitant
Ocular Myasthenia Other Serious 10/4/2007 Male 345 lb 2/15/2008 Physician United States
Primary
Concomitant
Renal Failure Hospitalization 12/3/2007 81 Male 2/21/2008 Other Health Professional Germany
Primary
Secondary
Concomitant
Blood Glucose Increased 81 Female 154 lb 2/25/2008 Consumer United States
Primary
Concomitant
Toxic Epidermal Necrolysis Life Threatening 12/19/2004 56 Female 2/29/2008 Physician Germany
Primary
Secondary
Respiratory Tract Congestion Hospitalization 1/1/2007 Male 301 lb 3/5/2008 Consumer United States
Primary
Concomitant
Pancytopenia Other Serious 2/5/2008 67 Male 3/12/2008 Consumer United States
Primary
Secondary
Concomitant
Urinary Retention Hospitalization 5/1/2007 60 Male 204 lb 3/17/2008 Physician Germany
Primary
Concomitant
Pancytopenia Other Serious 2/5/2008 67 Male 4/8/2008 Consumer United States
Primary
Secondary
Concomitant
Fatigue Hospitalization 1/1/2007 Male 301 lb 4/4/2008 Consumer United States
Primary
Concomitant
Wound Sepsis Hospitalization 2/28/2008 Male 170 lb 4/25/2008 Consumer United States
Primary
Secondary
Concomitant
Wound Infection Hospitalization 2/29/2008 Male 170 lb 5/2/2008 Physician United States
Primary
Secondary
Concomitant
Lactic Acidosis Other Serious 3/28/2008 59 Female 5/22/2008 Other Health Professional Germany
Primary
Concomitant
Urinary Tract Infection Hospitalization 5/17/2007 75 Female 230 lb 5/21/2008 Physician United States
Primary
Concomitant
Skin Necrosis Other Serious 3/1/2008 67 Male 185 lb 5/30/2008 Consumer Switzerland
Primary
Concomitant
Weight Increased Hospitalization 11/1/2006 61 Female 173 lb 4/10/2008 Consumer United States
Primary
Concomitant
Weight Decreased 5/1/2006 65 Female 197 lb 4/10/2008 Consumer United States
Primary
Concomitant
Sensory Loss Other Serious 5/23/2007 Male 251 lb 6/20/2008 Lawyer United States
Primary
Concomitant
Atrial Fibrillation Hospitalization 5/20/2008 Female 6/25/2008 Physician Italy
Primary
Concomitant
Gout 1/1/2008 70 Female 4/10/2008 Consumer United States
Primary
Concomitant
Syncope Other Serious 5/1/2008 Male 6/30/2008 Physician United States
Primary
Concomitant
Renal Failure Acute Hospitalization 3/25/2008 71 Male 7/7/2008 Other Health Professional Germany
Primary
Concomitant
White Blood Cell Count Abnormal 80 Male 7/24/2008 Consumer United States
Primary
Concomitant
Self-medication Other Serious 3/1/2008 67 Male 185 lb 7/11/2008 Consumer Switzerland
Primary
Concomitant
Swelling Other Serious 11/1/2007 59 Male 7/14/2008 Physician United States
Primary
Concomitant
Sinusitis 8/1/2007 64 Female 219 lb 4/10/2008 Consumer United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 5/17/2007 75 Female 230 lb 7/25/2008 Physician United States
Primary
Concomitant
Deafness Other Serious 75 Female 8/5/2008 Physician United States
Primary
Secondary
Syncope Other Serious 5/1/2008 Male 7/31/2008 Physician United States
Primary
Concomitant
Toxic Skin Eruption Hospitalization 3/14/2008 72 Female 8/12/2008 Physician France
Primary
Secondary
Concomitant
Deafness Unilateral Other Serious 75 Female 8/13/2008 Physician United States
Primary
Secondary
Deafness Unilateral Other Serious 75 Female 8/20/2008 Physician United States
Primary
Secondary
Deafness Unilateral Other Serious 75 Female 8/28/2008 Physician United States
Primary
Secondary
Lacunar Infarction Other Serious 1/1/2008 75 Female 202 lb 8/29/2008 Physician United States
Primary
Concomitant
Deafness Unilateral Other Serious 75 Female 9/3/2008 Physician United States
Primary
Secondary
Hyponatraemia Hospitalization 7/30/2008 66 Female 9/9/2008 Other Health Professional France
Primary
Secondary
Concomitant
Ulcer Haemorrhage Hospitalization 1/1/2003 57 Male 209 lb 9/12/2008 Consumer United States
Primary
Secondary
Concomitant
Shock Haemorrhagic Life Threatening 8/14/2008 83 Female 190 lb 9/12/2008 Consumer France
Primary
Concomitant
Syncope Other Serious 5/1/2008 Male 9/4/2008 Physician United States
Primary
Concomitant
Deafness Unilateral Other Serious 75 Female 9/16/2008 Physician United States
Primary
Secondary
Lactic Acidosis Hospitalization 3/26/2008 71 Female 10/1/2008 Other Health Professional Germany
Primary
Secondary
Concomitant
Myocardial Infarction Hospitalization 2/1/2007 57 Male 211 lb 10/1/2008 Consumer United States
Primary
Concomitant
Lactic Acidosis Hospitalization 1/1/2008 71 Female 10/7/2008 Other Health Professional France
Primary
Secondary
Concomitant
Myocardial Infarction Hospitalization 2/1/2007 57 Male 211 lb 10/13/2008 Pharmacist United States
Primary
Concomitant
Ulcer Haemorrhage Hospitalization 1/1/2003 57 Male 209 lb 10/17/2008 Physician United States
Primary
Secondary
Concomitant
Syncope Other Serious 5/1/2008 Male 11/3/2008 Physician United States
Primary
Concomitant
Deafness Unilateral Other Serious 7/14/2008 75 Female 11/25/2008 Physician United States
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 71 Male 12/4/2008 Other Health Professional France
Primary
Concomitant
Deafness Unilateral Other Serious 7/14/2008 75 Female 12/4/2008 Physician United States
Primary
Secondary
Weight Decreased Hospitalization 4/1/2008 Female 210 lb 12/5/2008 Consumer United States
Primary
Concomitant

Drug Data