Allopurinol combined with Fluorouracil

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Pyrexia Hospitalization 12/14/2005 Male 194 lb 1/5/2006 Other Health Professional France
Primary
Secondary
Concomitant
Respiratory Rate Increased Hospitalization 2/11/2006 59 Male 145 lb 2/13/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 10/28/2005 Male 2/22/2006 Physician Germany
Primary
Secondary
Concomitant
Metastases To Liver Hospitalization 11/7/2005 Male 2/22/2006 Physician Germany
Primary
Secondary
Concomitant
Rash Life Threatening 2/25/2005 73 Male 126 lb 2/21/2006 Physician Japan
Primary
Concomitant
Respiratory Distress Hospitalization 3/9/2006 59 Male 137 lb Other Health Professional United States
Primary
Secondary
Concomitant
Renal Failure Hospitalization 8/1/2002 Male 3/23/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Stomatitis Hospitalization 4/14/2006 59 Male 147 lb 4/14/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Peripheral Sensory Neuropathy Life Threatening 1/1/2006 Male 4/29/2006 Physician United States
Primary
Concomitant
Peripheral Sensory Neuropathy Life Threatening 1/1/2006 Male 4/29/2006 Physician United States
Primary
Concomitant
Sepsis Life Threatening 1/2/2006 Male 6/2/2006 Physician France
Primary
Secondary
Concomitant
Vomiting Hospitalization 8/21/1996 Male 11/1/1996 Physician United States
Primary
Secondary
Concomitant
Sepsis Life Threatening 1/2/2006 Male 6/28/2006 Physician France
Primary
Secondary
Concomitant
Gastroenteritis Hospitalization 6/10/2006 50 Male 126 lb 7/12/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Supraventricular Tachycardia Hospitalization 7/10/2006 Male 153 lb 8/8/2006 Other Health Professional Australia
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 7/14/2006 Male 8/10/2006 Pharmacist Japan
Primary
Concomitant
Oxygen Saturation Decreased Hospitalization 8/9/2006 60 Male 147 lb 8/10/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Oedema Peripheral Hospitalization 8/9/2006 60 Male 147 lb 8/29/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Pharyngeal Oedema Hospitalization 8/9/2006 60 Male 147 lb 9/7/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Supraventricular Tachycardia Hospitalization 7/8/2006 Male 153 lb 9/7/2006 Other Health Professional Australia
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 7/8/2006 Male 153 lb 9/8/2006 Other Health Professional Australia
Primary
Secondary
Concomitant
Pharmaceutical Product Complaint Death 12/22/2005 Male 10/27/2006 Consumer United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased 5/29/2006 Male 10/31/2006 Pharmacist Japan
Primary
Concomitant
Metabolic Acidosis Other Serious 8/25/2006 79 Male 179 lb 10/25/2006 Other Health Professional United States
Primary
Concomitant
Metabolic Acidosis Other Serious 8/25/2006 79 Male 179 lb 11/20/2006 Other Health Professional United States
Primary
Concomitant
Gastroenteritis Hospitalization 6/10/2006 50 Male 126 lb 12/18/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 6/10/2006 50 Male 126 lb 1/2/2007 Physician Japan
Primary
Secondary
Concomitant
Febrile Neutropenia Other Serious 7/20/2006 46 Male 3/7/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Wound Secretion Hospitalization 10/26/2004 75 Male 180 lb 3/14/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Cardiac Arrest Life Threatening 1/31/2007 73 Female 198 lb 3/21/2007
Primary
Concomitant
Colitis Hospitalization 1/11/2007 68 Male 5/25/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Diarrhoea Hospitalization 3/24/2007 77 Male 236 lb 6/5/2007 Consumer United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 4/28/2007 43 Male 7/3/2007
Primary
Secondary
Concomitant
Loss Of Consciousness Other Serious Female 7/3/2007 Consumer Norway
Primary
Concomitant
Stomatitis Hospitalization 2/18/2006 59 Male 139 lb 2/18/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Viral Upper Respiratory Tract Infection Hospitalization 2/18/2006 59 Male 139 lb 11/16/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Mucosal Inflammation Hospitalization 9/13/2007 Male 12/12/2007 Physician United States
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 11/14/2007 Male 12/21/2007 Physician Australia
Primary
Secondary
Concomitant
Mucosal Inflammation Hospitalization 9/13/2007 Male 1/2/2008 Physician United States
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 11/14/2007 Male 1/8/2008 Physician Australia
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 11/14/2007 Male 1/22/2008 Physician Australia
Primary
Secondary
Concomitant
Mucosal Inflammation Hospitalization 9/13/2007 Male 1/23/2008 Physician United States
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 4/6/2007 Male 1/29/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Mucosal Inflammation Hospitalization 9/13/2007 Male 2/6/2008 Physician United States
Primary
Secondary
Concomitant
Haematemesis Hospitalization 1/13/2008 Male 2/6/2008 Physician France
Primary
Concomitant
Melaena Hospitalization 1/13/2008 Male 2/27/2008 Physician France
Primary
Secondary
Concomitant
Melaena Hospitalization 1/13/2008 Male 3/12/2008 Physician France
Primary
Secondary
Concomitant
Weight Decreased Other Serious 11/1/2003 52 Female 190 lb 3/28/2008 United States
Primary
Secondary
Concomitant
Portal Vein Thrombosis Hospitalization 11/10/2006 69 Male 4/2/2008 Japan
Primary
Secondary
Concomitant
Rectal Haemorrhage Death 3/8/2008 Male 4/14/2008 Physician France
Primary
Concomitant
Weight Decreased Hospitalization 2/14/2008 Male 220 lb 4/25/2008 Physician Switzerland
Primary
Concomitant
Rectal Haemorrhage Death 3/8/2008 Male 5/14/2008 Physician France
Primary
Concomitant
Mucosal Inflammation Hospitalization 3/27/2008 57 Male 151 lb 5/16/2008 Physician United States
Primary
Concomitant
Persecutory Delusion Hospitalization 2/24/2008 62 Male 5/28/2008 Other Health Professional France
Primary
Secondary
Concomitant
Pyrexia Hospitalization 4/27/2008 57 Male 6/10/2008 Physician United States
Primary
Concomitant
Syncope Hospitalization 10/29/2007 Male 4/28/2008 Pharmacist United States
Primary
Concomitant
Pyrexia Hospitalization 4/27/2008 57 Male 7/3/2008 Physician United States
Primary
Concomitant
Mucosal Inflammation Hospitalization 3/27/2008 57 Male 151 lb 7/7/2008 Physician United States
Primary
Concomitant
Fatigue Hospitalization 2/14/2008 Male 220 lb 7/29/2008 Physician Switzerland
Primary
Concomitant
Renal Failure Hospitalization 6/5/2008 Female 8/18/2008 Physician Poland
Primary
Concomitant
Renal Failure Hospitalization 6/5/2008 Female 9/5/2008 Physician Poland
Primary
Concomitant
Renal Failure Acute Hospitalization 8/17/2008 75 Female 176 lb 9/9/2008 Other Health Professional Germany
Primary
Secondary
Concomitant
Renal Failure Hospitalization 6/5/2008 Female 9/16/2008 Physician Poland
Primary
Concomitant
Septic Shock Life Threatening 4/7/2008 56 Male 150 lb 9/22/2008 Other Health Professional Germany
Primary
Secondary
Concomitant
Renal Failure Hospitalization 6/5/2008 Female 9/26/2008 Physician Poland
Primary
Concomitant
Renal Failure Hospitalization 6/5/2008 Female 10/8/2008 Physician Poland
Primary
Concomitant
Ileal Ulcer Other Serious 10/1/2008 Male 172 lb 10/10/2008 Other Health Professional Canada
Primary
Secondary
Concomitant
Convulsion Hospitalization 6/10/2008 61 Male 10/14/2008 Other Health Professional Germany
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 9/21/2008 Male 172 lb 10/21/2008 Other Health Professional Canada
Primary
Secondary
Concomitant
Convulsion Hospitalization 6/10/2008 Male 10/22/2008 Other Health Professional France
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 10/30/2008 62 Male 142 lb 11/3/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 11/1/2003 Female 185 lb 11/21/2008 United States
Primary
Secondary
Concomitant
Malignant Neoplasm Progression Hospitalization 6/10/2008 61 Male 12/1/2008 Other Health Professional Germany
Primary
Secondary
Concomitant
Convulsion Hospitalization 6/10/2008 61 Male 12/9/2008 Other Health Professional Germany
Primary
Secondary
Concomitant
Sepsis Other Serious 9/21/2008 Male 172 lb 12/11/2008 Other Health Professional Canada
Primary
Secondary
Concomitant
Left Ventricular Dysfunction Life Threatening 11/26/2008 Male 12/19/2008 Physician France
Primary
Secondary
Concomitant
Sepsis Other Serious 1/26/2009 70 Male 178 lb 2/12/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Weight Decreased Other Serious 11/1/2003 Female 185 lb 2/19/2009 United States
Primary
Secondary
Concomitant
C-reactive Protein Increased Hospitalization 4/10/2008 3/2/2009 Physician Germany
Primary
Secondary
Concomitant
Sepsis Other Serious 1/26/2009 70 Male 178 lb 3/3/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Weight Decreased Other Serious 11/1/2003 Female 185 lb 3/5/2009 Other Health Professional United States
Primary
Secondary
Concomitant
C-reactive Protein Increased Hospitalization 4/10/2008 71 Male 139 lb 3/11/2009 Physician Germany
Primary
Secondary
Concomitant
Sepsis Other Serious 1/26/2009 70 Male 178 lb 3/12/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Weight Decreased Other Serious 11/1/2003 Female 185 lb 4/9/2009 Other Health Professional United States
Primary
Secondary
Concomitant
General Physical Health Deterioration Hospitalization 12/27/2008 Male 4/13/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Circulatory Collapse Hospitalization 3/18/2009 4/15/2009 Physician Germany
Primary
Secondary
Concomitant
Drug Hypersensitivity Hospitalization 4/3/2009 4/17/2009 Physician Germany
Primary
Secondary
Concomitant
Peripheral Ischaemia Other Serious 5/10/2009 Male 144 lb 5/18/2009 Consumer United States
Primary
Secondary
Concomitant
Prothrombin Time Prolonged Other Serious 5/10/2009 58 Male 144 lb 5/28/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Peripheral Ischaemia Other Serious 5/10/2009 Male 144 lb 6/5/2009 Consumer United States
Primary
Secondary
Concomitant
Platelet Count Decreased Other Serious 5/10/2009 58 Male 144 lb 6/18/2009 Physician United States
Primary
Secondary
Concomitant
Pneumonia Hospitalization 2/9/2009 Male 8/10/2009 Physician Germany
Primary
Secondary
Concomitant
Sudden Death Death 11/14/2007 76 8/11/2009 Physician France
Primary
Secondary
Concomitant
Wound Secretion Other Serious 10/26/2004 75 Male 180 lb 8/14/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Pneumonia Fungal Other Serious 11/28/2008 Male 311 lb 8/17/2009 Physician Germany
Primary
Secondary
Concomitant
Pneumonia Fungal Other Serious 11/28/2008 Male 311 lb 8/19/2009 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 5/10/2009 60 Male 152 lb 8/28/2009 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 2/1/2009 84 Male 9/30/2009 Physician Germany
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 7/27/2009 68 10/12/2009 Physician Japan
Primary
Secondary
Concomitant
Vomiting Hospitalization 10/7/2009 Female 126 lb 10/15/2009 United States
Primary
Secondary
Concomitant
General Physical Health Deterioration Death 1/26/2008 68 10/23/2009 Physician France
Primary
Secondary
Concomitant
Lung Infection Hospitalization 7/27/2009 68 10/28/2009 Physician Japan
Primary
Secondary
Concomitant
General Physical Health Deterioration Death 1/26/2008 68 10/30/2009 Physician France
Primary
Secondary
Concomitant
General Physical Health Deterioration Death 1/26/2008 Male 11/10/2009 Physician France
Primary
Secondary
Concomitant
General Physical Health Deterioration Death 1/26/2008 Male 11/11/2009 Physician United States
Primary
Secondary
Concomitant
Left Ventricular Dysfunction Hospitalization 10/20/2009 Female 126 lb 11/11/2009 United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 12/29/2007 Male 11/20/2009 Physician France
Primary
Secondary
Concomitant
Renal Impairment Other Serious 7/25/2008 76 Female 128 lb 11/25/2009 Physician Mexico
Primary
Secondary
Concomitant
General Physical Health Deterioration Death 1/26/2008 Male 12/4/2009 Physician United States
Primary
Secondary
Concomitant
Convulsion Hospitalization 10/18/2009 Male 12/23/2009 Physician United States
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Hospitalization 10/18/2009 58 Male 1/4/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Impairment Other Serious 7/25/2008 76 Female 128 lb 2/2/2010 Physician Mexico
Primary
Secondary
Concomitant
Nausea Death 76 Male 3/29/2010 Physician France
Primary
Secondary
Concomitant
Vomiting Death 2/1/2009 84 Male 137 lb 4/9/2010 France
Primary
Secondary
Concomitant
Lung Infection Hospitalization 7/27/2009 68 Male 132 lb 4/9/2010 Physician Japan
Primary
Secondary
Concomitant
Renal Impairment Other Serious 7/25/2008 76 Female 128 lb 4/26/2010 Physician Mexico
Primary
Secondary
Concomitant
Diarrhoea Other Serious 3/9/2010 68 Female 130 lb 5/11/2010 Physician United States
Primary
Secondary
Concomitant
Septic Shock Death 48 174 lb 5/19/2010 Pharmacist Canada
Primary
Concomitant
Diarrhoea Other Serious 3/9/2010 68 Female 130 lb 6/17/2010 Physician United States
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 3/24/2010 85 Female 156 lb 6/21/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 3/24/2010 85 Female 156 lb 6/21/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Diarrhoea Other Serious 3/9/2010 68 Female 130 lb 7/8/2010 Physician United States
Primary
Secondary
Concomitant
Wound Dehiscence Hospitalization 6/22/2010 64 Male 7/13/2010 Physician Belgium
Primary
Secondary
Concomitant
Post Procedural Bile Leak Hospitalization 3/30/2010 74 Male 7/28/2010 Physician Japan
Primary
Secondary
Concomitant
Mucosal Inflammation Hospitalization 5/7/2010 68 Male 168 lb 8/3/2010 Physician Germany
Primary
Secondary
Concomitant
Fistula Hospitalization 6/22/2010 64 Male 8/4/2010 Physician Belgium
Primary
Secondary
Concomitant
Post Procedural Bile Leak Hospitalization 12/24/2009 74 Male 8/5/2010 Physician Japan
Primary
Secondary
Concomitant
Wound Dehiscence Other Serious 5/27/2010 69 Male 8/5/2010 Physician Japan
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 3/24/2010 85 Female 156 lb 8/13/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Weight Decreased Other Serious 71 Male 265 lb 9/17/2010 Consumer United States
Primary
Concomitant
Pneumonia Hospitalization 2/9/2009 73 Male 9/24/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Sinus Tachycardia Hospitalization 9/8/2010 69 Male 160 lb 10/8/2010 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 11/1/2003 51 Female 185 lb 10/10/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 11/1/2003 51 Female 185 lb 10/21/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Death Other Serious 3/28/2010 81 Female 163 lb 11/18/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Vomiting Hospitalization 11/12/2010 70 Male 196 lb 11/25/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Toxic Skin Eruption Hospitalization 1/1/2010 63 Female 11/25/2010 Other Health Professional France
Primary
Secondary
Concomitant
Sinus Tachycardia Hospitalization 9/8/2010 69 Male 160 lb 11/26/2010 Physician United States
Primary
Secondary
Concomitant
Toxic Skin Eruption Hospitalization 1/1/2010 62 Female 12/2/2010 Consumer France
Primary
Secondary
Concomitant
Ischaemic Stroke Hospitalization 1/27/2010 74 Male 12/6/2010 Physician France
Primary
Secondary
Concomitant
Vomiting Hospitalization 11/12/2010 70 Male 196 lb 12/6/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Malignant Neoplasm Progression Hospitalization 1/27/2010 74 Male 11/29/2010 Other Health Professional France
Primary
Secondary
Concomitant
Syncope Other Serious 3/18/2010 82 Male 12/21/2010 Other Health Professional Switzerland
Primary
Concomitant
Muscular Weakness Death 3/18/2010 82 Male 12/27/2010 Other Health Professional Switzerland
Primary
Concomitant
Dehydration Hospitalization 11/12/2010 70 Male 196 lb 1/12/2011 Consumer United States
Primary
Secondary
Concomitant
Mucosal Inflammation Hospitalization 11/12/2010 70 Male 196 lb 1/13/2011 Consumer United States
Primary
Secondary
Concomitant
Decreased Appetite Hospitalization 11/12/2010 70 Male 196 lb 2/18/2011 Consumer United States
Primary
Secondary
Concomitant
Lethargy Hospitalization 3/21/2011 71 Male 146 lb 5/5/2011 Physician Australia
Primary
Concomitant
Mucosal Inflammation Death 3/30/2011 73 Male 120 lb 6/1/2011 Physician Japan
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 7/6/2008 72 Male 6/4/2011 Physician Japan
Primary
Concomitant

Drug Data