Allopurinol combined with Fludarabine Phosphate

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Red Blood Cell Count Decreased Hospitalization 12/29/2005 40 Male 170 lb 1/12/2006 Physician Australia
Primary
Secondary
Concomitant
Productive Cough Other Serious 10/18/2004 Male 183 lb 1/13/2006 United States
Primary
Secondary
Respiratory Syncytial Virus Infection Other Serious 12/16/2005 Male 160 lb 1/13/2006 United States
Primary
Secondary
Concomitant
Vomiting Other Serious 8/17/2004 Female 132 lb 1/17/2006 United States
Primary
Secondary
White Blood Cell Count Decreased Hospitalization 11/1/2004 75 Female 130 lb 1/24/2006 Other Health Professional Australia
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 11/1/2004 75 Female 130 lb 1/24/2006 Other Health Professional Australia
Primary
Secondary
Concomitant
Stevens-johnson Syndrome Required Intervention 2/6/2006 Male 214 lb 2/7/2006 United States
Primary
Secondary
Concomitant
Red Blood Cell Count Decreased Hospitalization 12/29/2005 40 Male 170 lb 2/14/2006 Physician Australia
Primary
Secondary
Concomitant
Vomiting Hospitalization 2/6/2006 59 Male 128 lb 2/23/2006 Physician Germany
Primary
Secondary
Concomitant
Tumour Lysis Syndrome Hospitalization 2/14/2006 68 Female 168 lb 3/3/2006 Consumer United States
Primary
Secondary
Concomitant
Tumour Lysis Syndrome Hospitalization 2/14/2006 68 Female 168 lb 3/13/2006 Consumer United States
Primary
Secondary
Concomitant
Thrombosis Required Intervention 2/1/2005 69 Male 253 lb 3/13/2006 Physician United States
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Life Threatening 11/26/2004 45 Male 161 lb 4/4/2006 Japan
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Life Threatening 11/26/2004 45 Male 161 lb 5/31/2006 Japan
Primary
Secondary
Concomitant
Platelet Count Decreased Hospitalization 9/19/2005 74 Female 123 lb 8/16/2006 Physician Belgium
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 9/19/2005 74 Female 123 lb 8/22/2006 Physician Belgium
Primary
Secondary
Concomitant
Serum Sickness Hospitalization 73 Male 132 lb 6/6/2006 Pharmacist United States
Primary
Concomitant
Cardiogenic Shock Other Serious 9/1/2006 68 Female 9/18/2006 Physician South Africa
Primary
Concomitant
Subcutaneous Abscess Hospitalization 2/1/2006 63 Male 187 lb 9/25/2006 Physician Germany
Primary
Secondary
Concomitant
Photosensitivity Reaction Hospitalization 3/1/2006 59 Male 9/25/2006 Consumer France
Primary
Secondary
Concomitant
Sinus Bradycardia Hospitalization 3/22/2006 67 Female 148 lb 9/28/2006 Other Health Professional Italy
Primary
Secondary
Concomitant
Vomiting Hospitalization 2/7/2006 59 Male 128 lb 9/27/2006 Physician Germany
Primary
Secondary
Concomitant
Granulocytopenia Hospitalization 11/23/2004 63 Male 179 lb 10/17/2006 Other Health Professional Hungary
Primary
Secondary
Concomitant
Renal Failure Life Threatening 1/28/2005 54 Female 106 lb 11/9/2006 Physician Japan
Primary
Concomitant
Pneumonia Fungal Hospitalization 3/29/2006 71 Male 176 lb 11/10/2006 Physician Germany
Primary
Secondary
Concomitant
Retroperitoneal Neoplasm Life Threatening 1/28/2005 54 Female 106 lb 11/20/2006 Physician Japan
Primary
Concomitant
Vitamin B12 Increased Other Serious 9/20/2006 56 Female 141 lb 11/10/2006 Physician United Kingdom
Primary
Concomitant
Tumour Lysis Syndrome Life Threatening 11/17/2006 67 Male 180 lb 11/29/2006 Physician Austria
Primary
Secondary
Concomitant
Tumour Lysis Syndrome Life Threatening 11/17/2006 67 Male 180 lb 12/12/2006 Physician Austria
Primary
Secondary
Concomitant
Syncope Vasovagal Hospitalization 9/19/2005 74 Female 123 lb 12/28/2006 Physician Belgium
Primary
Secondary
Concomitant
Ureteritis Other Serious 10/17/2006 73 Male 176 lb 1/10/2007 United States
Primary
Secondary
Concomitant
Pulmonary Fibrosis Other Serious 6/1/2006 77 Male 181 lb 3/22/2007 Physician Germany
Primary
Secondary
Concomitant
Anaemia Hospitalization 1/10/2007 53 Male 5/9/2007 Pharmacist United States
Primary
Concomitant
Haemolysis Hospitalization 5/15/2005 Female 123 lb 7/3/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Constipation Hospitalization 2/25/2005 Female 132 lb 7/5/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 6/8/2007 Female 7/10/2007 Physician United States
Primary
Secondary
Concomitant
Haemoptysis Other Serious 7/27/2005 Male 203 lb 7/13/2007 Consumer Hungary
Primary
Secondary
Concomitant
Mucosal Inflammation Hospitalization 3/23/2005 Male 192 lb 7/16/2007 Physician United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 7/1/2004 Male 193 lb 8/21/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pulmonary Fibrosis Other Serious 6/1/2006 Male 181 lb 8/24/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Sepsis Hospitalization 2/6/2006 Male 128 lb 9/21/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Haemolysis Hospitalization 5/15/2005 Female 123 lb 9/26/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Febrile Neutropenia Other Serious 12/3/2004 Male 169 lb 9/28/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Rash Generalised Life Threatening 9/18/2007 55 Male 10/1/2007 Other Health Professional Italy
Primary
Concomitant
Rash Life Threatening 9/18/2007 55 Male 10/17/2007 Other Health Professional Italy
Primary
Concomitant
Febrile Neutropenia Hospitalization 8/1/2005 Male 170 lb 10/26/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Febrile Neutropenia Other Serious 8/23/2006 76 Female 11/27/2006 Other Health Professional United States
Primary
Concomitant
Febrile Neutropenia Other Serious 8/18/2006 64 Female 11/27/2006 Physician United States
Primary
Concomitant
Pulmonary Embolism Life Threatening 5/24/2006 Male 192 lb 11/6/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Pneumonia Bacterial Death 6/20/2007 Male 11/10/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Neutropenia Other Serious 10/12/2005 64 Female 172 lb 11/19/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Tumour Lysis Syndrome Other Serious 47 Male 11/16/2007 Physician United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Life Threatening 10/14/2007 43 Female 249 lb 11/19/2007 Other Health Professional Italy
Primary
Concomitant
Tumour Lysis Syndrome Hospitalization 47 Female 11/20/2007 Other Health Professional United Kingdom
Primary
Secondary
Pneumonia Bacterial Death 6/20/2007 Male 12/7/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Serratia Infection Life Threatening 10/14/2007 43 Female 249 lb 12/5/2007 Other Health Professional Italy
Primary
Concomitant
Ventricular Fibrillation Other Serious 10/14/2007 43 Female 249 lb 12/7/2007 Other Health Professional Italy
Primary
Concomitant
Convulsion Other Serious 11/13/2007 Male 181 lb 12/13/2007 Pharmacist United Kingdom
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 6/20/2007 Female 146 lb 12/17/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Convulsion Other Serious 11/13/2007 Male 181 lb 1/17/2008 Consumer Canada
Primary
Concomitant
Febrile Neutropenia Hospitalization 7/20/2006 Male 170 lb 1/19/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Platelet Count Decreased Other Serious 3/10/2008 71 Male 163 lb 4/18/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Tremor Other Serious 3/10/2008 71 Male 165 lb 4/18/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 4/1/2008 Male 4/21/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 4/1/2008 Male 4/21/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Pyrexia Life Threatening 4/8/2008 Male 176 lb 4/21/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Pyrexia Life Threatening 4/8/2008 Male 176 lb 5/9/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Pyrexia Life Threatening 4/8/2008 Male 176 lb 5/14/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Pyrexia Life Threatening 4/8/2008 Male 176 lb 5/14/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 4/1/2008 Male 5/16/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 4/1/2008 Male 5/16/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Other Serious 4/9/2008 United States
Primary
Secondary
Concomitant
Tremor Hospitalization 6/6/2008 57 Female 183 lb 6/10/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Gouty Arthritis Disability 5/21/2008 Male 6/16/2008 Physician United Kingdom
Primary
Concomitant
Tremor Hospitalization 6/4/2008 57 Female 183 lb 6/10/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Gouty Arthritis Disability 5/21/2008 Male 6/23/2008 Physician United Kingdom
Primary
Concomitant
Gouty Arthritis Disability 5/21/2008 Male 7/7/2008 Physician United Kingdom
Primary
Concomitant
Mucosal Inflammation Hospitalization 3/23/2005 Male 192 lb 7/18/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Rash Maculo-papular Hospitalization 6/27/2008 51 Male 7/28/2008 Consumer Switzerland
Primary
Secondary
Concomitant
Tremor Hospitalization 6/4/2008 57 Female 183 lb 7/16/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Fungal Infection Life Threatening 4/19/2006 54 Male 8/15/2008 Physician Denmark
Primary
Secondary
Concomitant
Fungal Infection Life Threatening 4/19/2006 54 Male 8/21/2008 Physician Denmark
Primary
Secondary
Concomitant
Vitamin B12 Deficiency Hospitalization 5/19/2008 Male 209 lb 9/12/2008 Physician United States
Primary
Concomitant
Myocardial Infarction Life Threatening 9/21/2008 Male 223 lb 9/30/2008 United States
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 11/7/2006 43 Male 671 lb 9/22/2008 Physician United States
Primary
Secondary
Concomitant
Myocardial Infarction Life Threatening 9/21/2008 Male 223 lb 10/31/2008 United States
Primary
Secondary
Concomitant
Cardiac Arrest Death 8/18/2008 Male 144 lb 12/16/2008 Consumer United States
Primary
Concomitant
Colon Cancer Life Threatening 9/23/2008 12/18/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Cytomegalovirus Infection Other Serious 50 Male 12/22/2008 Other Health Professional South Africa
Primary
Concomitant
Pancytopenia Other Serious 25 Male 12/22/2008 Other Health Professional South Africa
Primary
Concomitant
Septic Shock Life Threatening 9/21/2008 Male 223 lb 1/6/2009 United States
Primary
Secondary
Concomitant
Septic Shock Life Threatening 9/21/2008 Male 223 lb 1/13/2009 United States
Primary
Secondary
Concomitant
Haemolysis Hospitalization 11/19/2008 Female 1/15/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Renal Failure Hospitalization 1/7/2009 81 Male 1/15/2009 Australia
Primary
Secondary
Concomitant
Renal Failure Hospitalization 1/7/2009 81 Male 1/19/2009 Other Health Professional Australia
Primary
Secondary
Concomitant
Renal Failure Hospitalization 1/7/2009 81 Male 165 lb 2/3/2009 Physician Australia
Primary
Secondary
Concomitant
Renal Failure Hospitalization 1/28/2009 81 Male 165 lb 2/4/2009 Physician Australia
Primary
Secondary
Concomitant
Toxic Encephalopathy Other Serious 52 Male 2/6/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 1/28/2009 81 Male 2/3/2009 Australia
Primary
Secondary
Concomitant
Renal Failure Hospitalization 1/7/2009 81 Male 2/4/2009 Australia
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 1/28/2009 81 Male 2/4/2009 Australia
Primary
Secondary
Concomitant
Renal Failure Hospitalization 1/7/2009 81 Male 2/3/2009 Australia
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 1/7/2009 Male 2/13/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Renal Failure Hospitalization 1/28/2009 81 Male 165 lb 2/24/2009 Other Health Professional Australia
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 1/7/2009 Male 2/27/2009 Physician United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Death 12/3/2008 55 Male 158 lb 2/24/2009 Physician United States
Primary
Secondary
Concomitant
Graft Versus Host Disease Hospitalization 2/1/2009 60 Male 3/11/2009 Spain
Primary
Secondary
Concomitant
Renal Impairment Death 52 Male 3/19/2009 Physician Japan
Primary
Concomitant
Febrile Neutropenia Other Serious 3/27/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Febrile Neutropenia Other Serious 3/27/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 1/1/2009 Male 198 lb 4/30/2009 Physician Germany
Primary
Secondary
Concomitant
Multi-organ Failure Death Male 5/1/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 1/1/2009 58 Male 198 lb 5/8/2009 Physician Germany
Primary
Secondary
Concomitant
Death Death 4/24/2009 Male 5/11/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 1/1/2009 58 Male 198 lb 5/12/2009 Physician Germany
Primary
Secondary
Concomitant
Oedema Death 3/1/2009 Male 5/12/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Progressive Multifocal Leukoencephalopathy Hospitalization 3/9/2009 Male 289 lb 5/22/2009 United States
Primary
Secondary
Concomitant
Sudden Death Death 4/24/2009 57 Male 5/28/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Progressive Multifocal Leukoencephalopathy Hospitalization 3/9/2009 Male 289 lb 6/8/2009 United States
Primary
Secondary
Concomitant
Virus Serology Test Positive Death 4/17/2009 58 Female 97 lb 6/2/2009 Physician Japan
Primary
Concomitant
Progressive Multifocal Leukoencephalopathy Hospitalization 2/5/2009 Female 119 lb 6/12/2009 Consumer United States
Primary
Secondary
Concomitant
Death Death 5/19/2009 Male 6/16/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Platelet Count Decreased Hospitalization 3/27/2009 Male 6/22/2009 Consumer France
Primary
Secondary
Concomitant
Death Death 4/24/2009 Male 6/23/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Progressive Multifocal Leukoencephalopathy Hospitalization 3/9/2009 Male 289 lb 6/26/2009 Physician United States
Primary
Secondary
Concomitant
Neutropenia Hospitalization 3/27/2009 Male 7/7/2009 Physician United Kingdom
Primary
Secondary
Oedema Hospitalization 3/1/2009 Male 7/9/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 7/21/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Virus Serology Test Positive Death 4/17/2009 58 Female 97 lb 7/10/2009 Physician Japan
Primary
Concomitant
Thrombocytopenia Other Serious 7/23/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Myocardial Ischaemia Death 5/19/2009 Male 8/31/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Neutropenia Hospitalization 3/27/2009 Male 9/2/2009 Physician United Kingdom
Primary
Secondary
Graft Versus Host Disease Death 9/9/2008 Male 168 lb 9/9/2009 Physician United Kingdom
Primary
Concomitant
Neutrophil Count Decreased Other Serious 11/21/2008 77 Female 12/4/2009 Physician Japan
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 12/1/2008 74 Female 12/16/2009 Physician Australia
Primary
Secondary
Concomitant
Toxoplasmosis Hospitalization 12/21/2009 Male 121 lb 12/23/2009 Consumer United States
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 12/1/2008 74 Female 12/23/2009 Other Health Professional Australia
Primary
Secondary
Concomitant
Transaminases Increased Hospitalization 1/5/2010 55 Male 151 lb 1/13/2010 Consumer United States
Primary
Secondary
Concomitant
Myelodysplastic Syndrome Other Serious 2/1/2010 69 Male 218 lb 3/25/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Myelodysplastic Syndrome Other Serious 2/1/2010 69 Male 3/26/2010 Physician
Primary
Concomitant
Skin Exfoliation Hospitalization 2/1/2010 68 Female 4/1/2010 Physician Italy
Primary
Secondary
Concomitant
Leukopenia Other Serious 9/30/2008 53 Female 4/1/2010 Physician Russian Federation
Primary
Secondary
Concomitant
Leukopenia Other Serious 9/30/2008 53 Female 4/6/2010 Physician Germany
Primary
Concomitant
Oxygen Saturation Decreased Other Serious 4/18/2010 57 Male 183 lb 5/3/2010 Physician United States
Primary
Concomitant
Po2 Decreased Other Serious 4/18/2010 57 Male 183 lb 5/14/2010 Physician United States
Primary
Concomitant
Pyrexia Other Serious 5/10/2010 64 Male 6/4/2010 Other Health Professional United Kingdom
Primary
Concomitant
Cytarabine Syndrome Life Threatening 5/10/2010 64 Male 6/18/2010 Other Health Professional United Kingdom
Primary
Concomitant
Rash Other Serious 2/25/2009 55 Male 6/28/2010 Physician Japan
Primary
Secondary
Concomitant
Pyrexia Other Serious 1/9/2009 58 Female 97 lb 7/28/2010 Physician Japan
Primary
Concomitant
Haemoptysis Life Threatening 4/11/2010 70 10/5/2010 Physician Australia
Primary
Secondary
Concomitant

Drug Data