Allopurinol combined with Fluconazole

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
White Blood Cell Count Decreased Hospitalization 11/9/2005 64 Male 171 lb 1/5/2006 United States
Primary
Secondary
Concomitant
Dehydration Hospitalization 11/19/2005 55 Male 236 lb 1/9/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Rectal Haemorrhage Hospitalization 75 Male 1/10/2006 Physician France
Primary
Secondary
Concomitant
Venoocclusive Disease Life Threatening 11/23/2005 63 Female 121 lb 1/12/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Dehydration Hospitalization 11/19/2005 55 Male 236 lb 1/20/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Rash Macular Other Serious 9/4/2005 77 Female 194 lb 1/17/2006 Other Health Professional United States
Primary
Concomitant
Renal Failure Required Intervention 8/25/2005 61 Male 11/15/2005 Other Health Professional United States
Primary
Concomitant
Renal Failure Acute Required Intervention 10/29/2005 40 Female 11/15/2005 Other Health Professional United States
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 7/12/2005 76 Male 1/10/2006 France
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 1/14/2006 54 Male 214 lb 1/25/2006 Physician Netherlands
Primary
Secondary
Concomitant
Skin Toxicity Other Serious 1/13/2006 32 Female 183 lb 1/25/2006 Physician Netherlands
Primary
Secondary
Concomitant
Dehydration Hospitalization 11/19/2005 55 Male 236 lb 2/2/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Pleural Effusion Hospitalization 9/30/2005 26 Male 247 lb 1/25/2006 Physician United States
Primary
Concomitant
Thrombophlebitis Hospitalization 5/14/2005 33 Male 2/7/2006 Physician United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 1/13/2006 32 Female 183 lb 2/1/2006 Physician Netherlands
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 1/14/2006 54 Male 214 lb 2/1/2006 Physician Netherlands
Primary
Secondary
Concomitant
Renal Failure Hospitalization 8/25/2005 61 Male 2/8/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombophlebitis Hospitalization 5/14/2005 33 Male 2/10/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Life Threatening 7/5/2001 34 Male 2/8/2006 United Kingdom
Primary
Concomitant
Tuberculosis Hospitalization 9/1/2005 Male 154 lb 2/16/2006 Italy
Primary
Concomitant
Therapy Non-responder Other Serious 1/13/2006 32 Female 183 lb 2/9/2006 Physician Netherlands
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 1/14/2006 54 Male 214 lb 2/10/2006 Physician Netherlands
Primary
Secondary
Concomitant
Respiratory Failure Required Intervention 10/7/2005 65 Male 2/10/2006 United Kingdom
Primary
Concomitant
Neutropenia Other Serious 1/21/2005 53 Male 2/16/2006 Physician Japan
Primary
Secondary
Concomitant
Tuberculosis Hospitalization 9/1/2005 Male 154 lb 2/24/2006 Italy
Primary
Concomitant
Pyrexia Other Serious 1/1/2003 38 Female 2/13/2006 Physician Germany
Primary
Secondary
Concomitant
Gamma-glutamyltransferase Increased Hospitalization 1/23/2006 91 Female 154 lb 2/28/2006 Consumer France
Primary
Secondary
Concomitant
Lymphocytosis Other Serious 7/25/2005 Male 3/6/2006 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 1/14/2006 54 Male 214 lb 2/23/2006 Physician Netherlands
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 1/13/2006 32 Female 190 lb 2/23/2006 Physician Netherlands
Primary
Secondary
Concomitant
Tuberculosis Hospitalization 9/1/2005 Male 154 lb 3/9/2006 Italy
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 1/13/2006 32 Female 183 lb 3/1/2006 Physician Netherlands
Primary
Secondary
Concomitant
Sudden Cardiac Death Other Serious 1/14/2006 54 Male 214 lb 3/1/2006 Physician Netherlands
Primary
Secondary
Concomitant
Renal Impairment Required Intervention 10/7/2005 65 Male 3/8/2006 United Kingdom
Primary
Concomitant
Tachycardia Other Serious 3/30/2004 44 Male 176 lb 3/14/2006 United States
Primary
Concomitant
Sudden Cardiac Death Other Serious 1/14/2006 54 Male 214 lb 3/8/2006 Physician Netherlands
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 1/13/2006 32 Female 168 lb 3/8/2006 Physician Netherlands
Primary
Secondary
Concomitant
Obstruction Hospitalization 74 Male 3/16/2006 Pharmacist United States
Primary
Secondary
Concomitant
Renal Failure Hospitalization 8/25/2005 61 Male 3/24/2006 Other Health Professional United States
Primary
Concomitant
Renal Failure Acute Hospitalization 2/1/2006 46 Male 170 lb 3/31/2006 Consumer United States
Primary
Concomitant
Thrombocytopenia Life Threatening 2/7/2006 40 Female 209 lb 3/28/2006 Physician France
Primary
Secondary
Concomitant
Septic Shock Life Threatening 2/4/2006 40 Female 209 lb 3/28/2006 Consumer France
Primary
Secondary
Concomitant
Urine Output Decreased Life Threatening 3/27/2006 47 Female 134 lb 3/31/2006 Pharmacist United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 1/14/2006 54 Male 214 lb 3/21/2006 Physician Netherlands
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 1/13/2006 32 Female 168 lb 3/21/2006 Physician Netherlands
Primary
Secondary
Concomitant
Platelet Count Decreased Hospitalization 1/13/2006 71 Male 137 lb 4/3/2006 Physician France
Primary
Secondary
Concomitant
Marrow Hyperplasia Other Serious 9/7/2005 67 Male 205 lb 4/5/2006 Physician United States
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 9/7/2005 67 Male 205 lb 4/5/2006 Physician United States
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 2/4/2006 40 Female 209 lb 4/13/2006 Physician France
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 2/7/2006 40 Female 209 lb 4/14/2006 Physician France
Primary
Secondary
Concomitant
Vomiting Disability 3/7/2006 56 Female 4/14/2006 Physician Japan
Primary
Concomitant
Syncope Required Intervention 1/1/2005 Male 4/14/2006 Physician Switzerland
Primary
Concomitant
Renal Failure Acute Other Serious 2/1/2006 46 Male 170 lb 4/27/2006 Consumer United States
Primary
Concomitant
Vomiting Disability 3/7/2006 56 Female 4/25/2006 Physician Japan
Primary
Concomitant
Vomiting Life Threatening 9/29/2005 68 Female 196 lb 4/25/2006 United States
Primary
Concomitant
Stomatitis Hospitalization 3/27/2006 Male 5/8/2006 Physician Germany
Primary
Secondary
Concomitant
Septic Shock Life Threatening 2/4/2006 40 Female 209 lb 5/8/2006 Physician France
Primary
Secondary
Concomitant
Thrombin Time Prolonged Life Threatening 9/7/2005 63 Male 175 lb 5/9/2006 Physician Hungary
Primary
Secondary
Concomitant
Septic Shock Life Threatening 2/7/2006 40 Female 209 lb 5/15/2006 Physician France
Primary
Secondary
Concomitant
Troponin I Increased Hospitalization 3/14/2006 84 Male 112 lb 5/22/2006 Physician United Kingdom
Primary
Concomitant
Thrombocytopenia Life Threatening 2/4/2006 40 Female 209 lb 5/23/2006 Physician France
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Life Threatening 3/9/2006 43 Male 5/24/2006 Japan
Primary
Concomitant
White Blood Cell Count Increased Life Threatening 3/29/2006 72 Male 229 lb 5/31/2006 Pharmacist United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 3/21/2006 76 Male 150 lb 6/7/2006 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 3/21/2006 76 Male 150 lb 6/16/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Life Threatening 9/29/2005 68 Female 196 lb 7/6/2006 United States
Primary
Concomitant
Urine Output Decreased Life Threatening 3/27/2006 47 Female 134 lb 5/24/2006 Pharmacist United States
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 9/7/2005 67 Male 205 lb 7/5/2006 Physician United States
Primary
Secondary
Concomitant
Troponin I Increased Hospitalization 3/14/2006 84 Male 112 lb 7/7/2006 Physician United Kingdom
Primary
Concomitant
White Blood Cell Count Decreased Life Threatening 3/9/2006 43 Male 7/11/2006 Japan
Primary
Concomitant
Prothrombin Time Prolonged Life Threatening 3/8/2006 73 Male 5/24/2006 Japan
Primary
Concomitant
White Blood Cell Count Increased Life Threatening 3/8/2006 73 Male 7/11/2006 Japan
Primary
Concomitant
Prothrombin Time Prolonged Life Threatening 3/8/2006 73 Male 7/18/2006 Japan
Primary
Concomitant
Tuberculosis Hospitalization 9/1/2005 Male 154 lb 7/28/2006 Italy
Primary
Concomitant
Capillary Leak Syndrome Hospitalization 5/10/2006 Male 7/31/2006 Physician Spain
Primary
Secondary
Concomitant
Simple Partial Seizures Death 6/4/2006 89 Male 7/28/2006 Other Health Professional United Kingdom
Primary
Concomitant
Sepsis Death 7/16/2006 67 Male 8/2/2006 Physician United States
Primary
Secondary
Concomitant
Swelling Face Other Serious 12/1/2005 63 Male 183 lb 8/15/2006 Consumer United Kingdom
Primary
Secondary
Concomitant
Swelling Face Other Serious 12/1/2005 63 Male 183 lb 8/23/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Troponin I Increased Hospitalization 3/14/2006 84 Male 112 lb 8/23/2006 Physician United Kingdom
Primary
Concomitant
Chest Discomfort Disability 2/16/2006 43 Female 8/30/2006 Australia
Primary
Secondary
Concomitant
Renal Failure Acute Death 1/1/2006 73 Male 246 lb 8/29/2006 Physician United States
Primary
Concomitant
Febrile Neutropenia Hospitalization 3/14/2004 68 Male 168 lb 9/1/2006 United States
Primary
Secondary
Concomitant
Ultrasound Abdomen Abnormal Hospitalization 1/1/2006 83 Female 227 lb 9/8/2006 Physician France
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Life Threatening 9/13/2004 56 Female 190 lb 9/8/2006 United States
Primary
Concomitant
Sepsis Death 7/16/2006 67 Male 9/6/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Capillary Leak Syndrome Hospitalization 5/10/2006 Male 9/22/2006 Physician Spain
Primary
Secondary
Concomitant
Cardiac Failure Hospitalization 5/10/2006 Male 10/9/2006 Physician Spain
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 6/2/2006 61 Female 180 lb 9/28/2006 Physician United States
Primary
Secondary
Concomitant
Tooth Abscess Other Serious 9/1/2005 60 Female 10/19/2006 Physician United Kingdom
Primary
Concomitant
Granulocytopenia Hospitalization 11/23/2004 63 Male 179 lb 10/17/2006 Other Health Professional Hungary
Primary
Secondary
Concomitant
Tongue Disorder Hospitalization 6/26/2006 44 Male 194 lb 10/27/2006 Other Health Professional France
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 9/19/2006 68 Male 11/8/2006 Physician United States
Primary
Concomitant
Pleural Effusion Hospitalization 2/6/2006 45 Male 159 lb 11/6/2006 Physician France
Primary
Concomitant
Respiratory Disorder Life Threatening 63 Male 331 lb 11/21/2006 Pharmacist United States
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 3/2/2006 70 Male 149 lb 11/7/2006 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Life Threatening 9/19/2006 68 Male 11/28/2006 Other Health Professional United States
Primary
Concomitant
Venoocclusive Disease Other Serious 10/14/2006 11 Female 60 lb 11/30/2006 Physician Canada
Primary
Concomitant
Central Nervous System Lymphoma Hospitalization 70 Female 12/1/2006 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Rash Other Serious 8/1/2006 Female 121 lb 12/21/2006 Physician Hungary
Primary
Concomitant
Vomiting Other Serious 10/1/2005 Male 180 lb 12/27/2006 Other Health Professional United States
Primary
Concomitant
Disease Progression Death 2/11/2006 Female 2/20/2007 Consumer United States
Primary
Secondary
Concomitant
Pco2 Abnormal Other Serious 2/1/2007 Female 250 lb 3/2/2007 Other Health Professional United States
Primary
Concomitant
Thrombocytopenia Life Threatening 9/19/2006 68 Male 2/22/2007 Other Health Professional United States
Primary
Concomitant
Coronary Artery Disease Hospitalization 12/4/2006 Male 162 lb 3/5/2007 Physician United States
Primary
Secondary
Concomitant
Emphysema Life Threatening 9/6/2005 Male 152 lb 3/20/2007 Physician Belgium
Primary
Concomitant
Torsade De Pointes Other Serious 3/6/2007 45 Male 165 lb 3/19/2007 Other Health Professional United States
Primary
Concomitant
Vomiting Other Serious 10/1/2005 Male 180 lb 3/28/2007 Other Health Professional United States
Primary
Concomitant
Cardiac Failure Death 3/19/2007 52 Female 3/30/2007 Physician Czech Republic
Primary
Secondary
Concomitant
Weight Increased Other Serious 4/1/2006 35 Male 3/26/2007 United States
Primary
Secondary
Concomitant
Tachypnoea Hospitalization 3/20/2007 Male 4/6/2007 United States
Primary
Concomitant
Weight Increased Hospitalization 3/18/2007 61 Male 4/6/2007 United States
Primary
Concomitant
Vomiting Other Serious 10/1/2005 Male 180 lb 4/27/2007 Physician United States
Primary
Concomitant
Lichenoid Keratosis Disability 2/14/2007 44 Male 4/18/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Tachycardia Hospitalization 1/20/2007 62 Female 4/24/2007 Other Health Professional United Kingdom
Primary
Concomitant
Vomiting Other Serious 10/1/2005 Male 180 lb 5/2/2007 Physician United States
Primary
Concomitant
Cardiac Failure Death 3/19/2007 52 Female 5/8/2007 Consumer Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Life Threatening 4/9/2007 19 Male 164 lb 5/24/2007 Physician United States
Primary
Secondary
Concomitant
Lymphocytosis Other Serious 7/25/2005 Male 6/1/2007 Physician United States
Primary
Secondary
Concomitant
Ventricular Tachycardia Life Threatening 4/9/2007 19 Male 167 lb 6/4/2007 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Life Threatening 4/9/2007 19 Male 167 lb 6/7/2007 Physician United States
Primary
Secondary
Concomitant
Cardiac Failure Death 3/19/2007 52 Female 6/23/2007 Other Health Professional Czech Republic
Primary
Secondary
Concomitant
Cardiac Failure Death 3/19/2007 52 Female 6/21/2007 Czech Republic
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 9 Male 7/10/2007 Other Health Professional Sweden
Primary
Concomitant
Febrile Neutropenia Hospitalization 6/8/2007 Female 7/10/2007 Physician United States
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 1/1/1999 55 Male 7/25/2007 Italy
Primary
Secondary
White Blood Cell Count Decreased Other Serious 9 Male 8/3/2007 Other Health Professional Sweden
Primary
Concomitant
Tremor Hospitalization 7/1/2007 66 Female 144 lb 7/30/2007 Physician United States
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 8/4/2007 Italy
Primary
Secondary
Thrombocytopenia Hospitalization 7/22/2007 82 Female 8/6/2007 Other Health Professional United States
Primary
Concomitant
Hyperkalaemia Hospitalization 3/21/2006 76 Male 150 lb 8/16/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Interacting
Hepatitis C Other Serious 2/7/2002 Male 209 lb 8/16/2007 Consumer Japan
Primary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 7/1/2007 66 Female 144 lb 8/13/2007 Physician United States
Primary
Secondary
Concomitant
Hepatotoxicity Other Serious 38 Female 8/3/2007 Germany
Primary
Secondary
Concomitant
Blood Creatinine Increased Hospitalization 5/21/2007 Male 5/22/2007 United States
Primary
Concomitant
International Normalised Ratio Increased Other Serious Female 9/1/2007 Other Health Professional Denmark
Primary
Secondary
Concomitant
Vertigo Positional Other Serious 8/9/2007 Female 210 lb 9/10/2007 Physician United States
Primary
Concomitant
Toxic Epidermal Necrolysis Required Intervention 10 Male 9/17/2007 Other Health Professional Sweden
Primary
Secondary
Concomitant
Hypotension Death 3/20/2007 78 Female 9/24/2007 Pharmacist United States
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 1/1/1999 55 Male 9/18/2007 Italy
Primary
Secondary
Cardiotoxicity 1/18/2007 47 Female 180 lb 1/25/2007 Pharmacist United States
Primary
Concomitant
Vertigo Positional Other Serious 8/9/2007 Female 210 lb 10/18/2007 Physician United States
Primary
Concomitant
Febrile Neutropenia Other Serious 8/23/2006 76 Female 11/27/2006 Other Health Professional United States
Primary
Concomitant
Thrombocytopenia Life Threatening 4/13/2003 64 Male 11/28/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Azotaemia Life Threatening 8/1/2007 Male 10/25/2007 Denmark
Primary
Concomitant
Blood Pressure Decreased Life Threatening 10/1/2007 66 Male 132 lb 11/7/2007 Other Health Professional United Kingdom
Primary
Concomitant
Rash Other Serious 2/3/2007 60 Male 132 lb 11/5/2007 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Life Threatening 10/28/2007 14 Female 126 lb 11/12/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Staphylococcal Bacteraemia Life Threatening 10/7/2007 14 Male 203 lb 11/8/2007 Physician United States
Primary
Secondary
Concomitant
Blood Pressure Decreased Life Threatening 10/1/2007 66 Male 132 lb 11/15/2007 Other Health Professional United Kingdom
Primary
Concomitant

Drug Data