Allopurinol combined with Enalapril

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Rash Required Intervention 1/4/2006 57 Male 163 lb 1/18/2006 Pharmacist United States
Primary
Concomitant
Pyrexia Other Serious 1/1/2006 69 Male 143 lb 1/23/2006 Chile
Primary
Concomitant
Gamma-glutamyltransferase Increased Other Serious 12/12/2005 Female 127 lb 1/31/2006 Physician Spain
Primary
Concomitant
Melaena Hospitalization 11/8/2005 65 Male 1/27/2006 Pharmacist United States
Primary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 8/12/2005 61 Male 2/10/2006 Other Health Professional Italy
Primary
Secondary
Concomitant
Gamma-glutamyltransferase Increased Other Serious 12/12/2005 Female 127 lb 2/15/2006 Physician Spain
Primary
Concomitant
Toxic Epidermal Necrolysis Other Serious 9/29/2003 Male 5/16/2006 United States
Primary
Secondary
Concomitant
Rash Hospitalization 12/6/2005 92 Female 5/24/2006 Other Health Professional Sweden
Primary
Secondary
Concomitant
Urinary Bladder Haemorrhage Required Intervention 6/19/2006 69 Male 8/10/2006 Physician United States
Primary
Concomitant
Renal Failure Life Threatening 1/23/2006 71 Male 187 lb 8/24/2006 Physician Germany
Primary
Concomitant
Mitochondrial Myopathy Other Serious 52 Female 8/31/2006 Austria
Primary
Concomitant
Cough Life Threatening 4/10/2005 38 Male 9/11/2006 Physician Japan
Primary
Secondary
Concomitant
Visual Acuity Reduced Other Serious 1/1/1997 52 Female 143 lb 9/7/2006 Physician Austria
Primary
Concomitant
Vomiting Hospitalization 1/24/2007 70 Male 231 lb 5/5/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Hyponatraemia Hospitalization 3/5/2007 78 Male 5/18/2007
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 8/27/2006 Male 141 lb 5/24/2007 Austria
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 72 Male 5/25/2007 Consumer United States
Primary
Concomitant
Hepatic Enzyme Increased Other Serious 5/29/2007 37 Male 292 lb 6/18/2007 Pharmacist United States
Primary
Concomitant
Somnolence 3/8/2007 54 Male 181 lb 6/27/2007 Consumer United States
Primary
Concomitant
Hepatitis C Other Serious 2/7/2002 Male 209 lb 8/16/2007 Consumer Japan
Primary
Concomitant
Drug Interaction Death 79 Female 8/16/2007 Sweden
Primary
Concomitant
Interacting
Urine Leukocyte Esterase Positive Hospitalization 6/4/2007 60 Female 8/23/2007 Physician United States
Primary
Secondary
Concomitant
Orthopnoea Hospitalization 1/1/2007 62 Male 159 lb 8/31/2007 Physician Switzerland
Primary
Concomitant
White Blood Cell Count Decreased Life Threatening 11/2/2007 15 Female 208 lb 11/19/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Venoocclusive Disease Life Threatening 11/5/2007 15 Female 208 lb 12/3/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Disorder Hospitalization 12/1/2007 73 Female 4/30/2008 Consumer United Kingdom
Primary
Concomitant
Intentional Drug Misuse Other Serious 1/1/2009 2/11/2009 Physician Brazil
Primary
Secondary
Concomitant
Blindness Other Serious Male 2/19/2009 Consumer United States
Primary
Concomitant
Weight Increased Other Serious 1/1/2007 Male 216 lb 2/22/2009 United States
Primary
Secondary
Concomitant
Dyspepsia Male 2/24/2009 United States
Primary
Concomitant
Weight Increased Other Serious 1/1/2007 Male 216 lb 2/26/2009 United States
Primary
Secondary
Concomitant
Mental Status Changes Required Intervention 12/9/2008 Male 2/20/2009 Pharmacist United States
Primary
Concomitant
Hypoglycaemia Life Threatening 11/14/2008 83 Male 3/10/2009 Pharmacist Germany
Primary
Concomitant
Interacting
Urinary Bladder Haemorrhage Required Intervention 6/19/2006 69 Male 3/2/2009 Physician United States
Primary
Secondary
Concomitant
Rhabdomyolysis Life Threatening 9/22/2008 74 Male 276 lb 3/11/2009 Physician Germany
Primary
Concomitant
Interacting
Hypoglycaemia Life Threatening 9/22/2008 74 Male 276 lb 3/12/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Hypoglycaemia Life Threatening 11/14/2008 83 Male 3/12/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Hypoglycaemia Life Threatening 11/14/2008 83 Male 3/13/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Vasodilatation Hospitalization 5/26/2006 3/18/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Colon Cancer Other Serious 11/1/2008 62 Male 3/20/2009 Physician Germany
Primary
Concomitant
Purpura Hospitalization 3/17/2009 75 Male 3/27/2009 Physician France
Primary
Concomitant
Hypoglycaemia Life Threatening 12/14/2008 85 Female 154 lb 4/2/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Parathyroid Tumour Benign Other Serious 12/16/2008 53 Male 4/2/2009 Physician Germany
Primary
Secondary
Concomitant
Hypoglycaemia Other Serious 12/14/2008 85 Female 4/3/2009 Consumer Germany
Primary
Secondary
Concomitant
Hypoglycaemia Life Threatening 11/14/2008 83 Male 4/7/2009 Pharmacist Germany
Primary
Concomitant
Interacting
Syncope Life Threatening 1/10/2009 79 Male 214 lb 4/7/2009 Other Health Professional Germany
Primary
Concomitant
Hypertension Other Serious 3/1/2009 Male 4/8/2009 Consumer United States
Primary
Concomitant
Pulmonary Congestion Other Serious 64 Male 232 lb 4/9/2009 United States
Primary
Concomitant
Unresponsive To Stimuli Other Serious 12/14/2008 85 Female 4/9/2009 Consumer Germany
Primary
Secondary
Concomitant
Transient Ischaemic Attack Other Serious 64 Male 232 lb 4/10/2009 United States
Primary
Concomitant
Pneumonia Hospitalization 3/23/2009 73 Male 243 lb 4/10/2009 Other Health Professional United States
Primary
Concomitant
Hypoglycaemia Life Threatening 11/14/2008 83 Male 150 lb 4/14/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Thyroglossal Cyst Other Serious 8/8/2001 40 Male 227 lb 4/15/2009 United States
Primary
Concomitant
Transaminases Increased Life Threatening 1/20/2009 Male 4/16/2009 Consumer France
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Death 4/1/2009 69 Female 229 lb 4/17/2009 Pharmacist United States
Primary
Concomitant
Upper Respiratory Tract Infection Other Serious 6/15/2004 49 Male 276 lb 4/21/2009 United States
Primary
Concomitant
Toxic Epidermal Necrolysis Other Serious 69 Female 229 lb 4/21/2009 Pharmacist United States
Primary
Concomitant
Hypertensive Crisis Life Threatening 1/19/2009 Male 4/22/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Parathyroid Tumour Benign Other Serious 12/16/2008 53 Male 4/28/2009 Physician Germany
Primary
Secondary
Concomitant
Nerve Compression Hospitalization 4/28/2009 Female 5/20/2009 Pharmacist United States
Primary
Concomitant
Mental Status Changes Other Serious 3/1/2009 Male 5/20/2009 Other Health Professional United States
Primary
Concomitant
Salivary Hypersecretion Hospitalization 9/1/2008 Male 165 lb 6/9/2009 Germany
Primary
Secondary
Concomitant
Pleural Effusion Other Serious 11/21/2008 70 Female 148 lb 6/11/2009 Physician Germany
Primary
Concomitant
Progressive Multifocal Leukoencephalopathy Hospitalization 2/5/2009 Female 119 lb 6/12/2009 Consumer United States
Primary
Secondary
Concomitant
Lower Respiratory Tract Infection Other Serious 1/29/2009 74 Male 6/18/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Lower Respiratory Tract Infection Other Serious 1/29/2009 74 Male 6/18/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Death 1/1/2009 69 Female 6/22/2009 Pharmacist United States
Primary
Concomitant
Haemolytic Anaemia Hospitalization 3/1/2009 30 Female 6/24/2009 Pharmacist Spain
Primary
Concomitant
Rhabdomyolysis Life Threatening 9/8/2008 74 Male 276 lb 6/25/2009 Physician Germany
Primary
Concomitant
Interacting
Visual Impairment Other Serious 1/1/2007 79 Male 7/2/2009 Consumer United States
Primary
Concomitant
Vomiting Other Serious 1/1/2007 Male 7/7/2009 Physician United States
Primary
Concomitant
Vomiting Other Serious 6/15/2009 Female 128 lb 7/13/2009 Physician Germany
Primary
Concomitant
Progressive Multifocal Leukoencephalopathy Hospitalization 2/5/2009 Female 119 lb 10/27/2009 Consumer United States
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 10/21/2008 72 Female 10/23/2009 United Kingdom
Primary
Concomitant
Treatment Noncompliance Hospitalization 54 Male 281 lb 10/22/2009 United States
Primary
Concomitant
Thrombocytopenia Hospitalization 10/13/2009 Male 175 lb 10/27/2009 Physician United Kingdom
Primary
Concomitant
Liver Function Test Abnormal Disability 9/25/2009 80 Male 198 lb 11/3/2009 Physician Germany
Primary
Concomitant
Surgery Death 61 Male 280 lb 10/26/2009 United States
Primary
Concomitant
Liver Function Test Abnormal Disability 9/25/2009 80 Male 198 lb 11/4/2009 Physician Germany
Primary
Concomitant
Weight Decreased Other Serious 76 Male 10/26/2009 United States
Primary
Concomitant
Troponin I Increased Other Serious 11/3/2009 Male 152 lb 11/6/2009 Physician Chile
Primary
Secondary
Concomitant
Sepsis Life Threatening 10/24/2009 Female 11/6/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Angina Unstable Other Serious 11/3/2009 Male 152 lb 11/10/2009 Physician Chile
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Life Threatening 5/1/2009 70 Male 11/10/2009 Physician Germany
Primary
Secondary
Concomitant
Interacting
Angina Unstable Other Serious 11/3/2009 Male 152 lb 11/11/2009 Physician Chile
Primary
Secondary
Concomitant
Heart Rate Increased 11/1/2008 75 Female 11/13/2009 Consumer United States
Primary
Concomitant
Renal Failure Acute Hospitalization 9/8/2009 63 Male 11/16/2009 Other Health Professional Sweden
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Hospitalization 79 Female 11/18/2009 United States
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 81 Female 11/18/2009 United States
Primary
Concomitant
Varicose Vein Hospitalization 73 Female 11/24/2009 United States
Primary
Concomitant
Pancreatitis Acute Hospitalization 11/23/2007 Female 181 lb 11/30/2009 Physician Germany
Primary
Concomitant
Influenza Like Illness 1/1/2009 58 Female 225 lb 10/29/2009 Other Health Professional United States
Primary
Concomitant
Drug Interaction Hospitalization 5/19/2009 70 Male 12/7/2009 Other Health Professional Germany
Primary
Concomitant
Interacting
Arthralgia 10/12/2009 Male 215 lb 12/16/2009 Consumer United States
Primary
Concomitant
Renal Impairment Hospitalization 80 Male 12/9/2009 Lawyer United States
Primary
Concomitant
Sepsis Life Threatening 10/24/2009 Female 12/18/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Renal Failure Hospitalization 8/20/2009 Female 12/22/2009 Physician Canada
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 12/1/2008 Male 462 lb 1/12/2010 Physician United States
Primary
Concomitant
Renal Failure Acute Hospitalization 8/26/2009 73 Female 2/2/2010 Other Health Professional Spain
Primary
Secondary
Concomitant
Unresponsive To Stimuli Other Serious 12/14/2008 85 Female 2/4/2010 Consumer Germany
Primary
Secondary
Concomitant
Hypoglycaemia Life Threatening 12/14/2008 85 Female 154 lb 2/5/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Weight Increased Hospitalization 66 Female 234 lb 5/6/2010 United States
Primary
Concomitant
Rash Macular 4/21/2010 65 Male 276 lb 5/10/2010 Other Health Professional United States
Primary
Concomitant
Therapeutic Agent Toxicity Life Threatening 5/1/2009 70 Male 5/18/2010 Physician Germany
Primary
Secondary
Concomitant
Interacting
Renal Failure Other Serious 1/1/2010 48 Male 145 lb 5/19/2010 Consumer United States
Primary
Concomitant
Therapeutic Response Decreased Other Serious 12/1/2009 78 Male 176 lb 5/28/2010 Physician Spain
Primary
Concomitant
Lung Infiltration Hospitalization 5/25/2010 75 Male 179 lb 6/1/2010 United States
Primary
Concomitant
Speech Disorder Hospitalization 67 Male 6/4/2010 Other Health Professional Germany
Primary
Secondary
Therapeutic Response Decreased Other Serious 12/1/2009 78 Male 176 lb 6/8/2010 Physician Spain
Primary
Concomitant
Intestinal Haemorrhage Hospitalization 6/10/2010 74 Male 183 lb 7/27/2010 Other Health Professional Spain
Primary
Secondary
Concomitant
Rash 4/30/2009 73 Male 180 lb 7/31/2010 Consumer United States
Primary
Concomitant
Therapeutic Response Decreased Other Serious 1/1/2007 34 Female 216 lb 8/2/2010 Other Health Professional United States
Primary
Concomitant
Anaphylactic Shock Life Threatening 7/26/2010 72 Male 198 lb 8/17/2010 Other Health Professional Germany
Primary
Concomitant
Bursitis Hospitalization 6/15/2010 87 Male 181 lb 8/19/2010 Other Health Professional Sweden
Primary
Secondary
Concomitant
Hypotension Life Threatening 8/6/2010 Female 8/25/2010 Physician United Kingdom
Primary
Concomitant
Wound Other Serious 3/13/2003 66 Male 174 lb 8/25/2010 United States
Primary
Concomitant
Skin Burning Sensation Male 198 lb 8/28/2010 United States
Primary
Concomitant
Toe Amputation Hospitalization 3/22/2010 72 Male 163 lb 9/1/2010 Physician Germany
Primary
Concomitant
Rhabdomyolysis Life Threatening 9/8/2008 74 Male 276 lb 9/1/2010 Physician Germany
Primary
Concomitant
Interacting
Disease Progression Death 3/11/2010 77 Male 134 lb 9/3/2010 Physician Chile
Primary
Secondary
Concomitant
Disease Progression Other Serious 2/3/2010 75 Female 9/8/2010 Physician Germany
Primary
Concomitant
Hypoglycaemia Life Threatening 9/22/2008 74 Male 276 lb 9/8/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Urine Output Decreased Other Serious 8/31/2010 78 Male 9/8/2010 Consumer Colombia
Primary
Concomitant
Renal Failure Acute Other Serious 9/22/2008 74 Male 276 lb 9/9/2010 Other Health Professional Germany
Primary
Concomitant
Interacting
Renal Failure Acute Other Serious 9/22/2008 74 Male 276 lb 9/9/2010 Other Health Professional Germany
Primary
Concomitant
Interacting
Toxic Epidermal Necrolysis Death 67 203 lb 9/14/2010 Other Health Professional Germany
Primary
Concomitant
Drug Ineffective 1/1/2009 66 Male 185 lb 9/16/2010 Consumer United States
Primary
Concomitant
Intestinal Haemorrhage Hospitalization 6/10/2010 74 Male 183 lb 10/6/2010 Other Health Professional Spain
Primary
Secondary
Concomitant
Platelet Count Decreased 3/1/2009 60 Male 330 lb 10/26/2010 Physician United States
Primary
Concomitant
Interstitial Lung Disease Hospitalization 2/2/2010 71 Male 10/29/2010 Other Health Professional Sweden
Primary
Concomitant
Cardiovascular Disorder Hospitalization 1/20/2010 72 Male 202 lb 11/2/2010 Physician Germany
Primary
Concomitant
Infection Hospitalization 11/16/2007 47 Male 237 lb 1/3/2011 Physician Germany
Primary
Secondary
Concomitant
Asthenia Hospitalization Female 157 lb 1/18/2011 Physician Germany
Primary
Secondary
Concomitant
Poor Venous Access Other Serious 3/13/2003 66 Male 174 lb 1/20/2011 United States
Primary
Concomitant
Hepatic Enzyme Increased Other Serious 1/1/2009 43 Female 238 lb 1/20/2011 Physician United States
Primary
Concomitant
Cataract Other Serious Male 187 lb 1/27/2011 Consumer Brazil
Primary
Secondary
Concomitant
Renal Failure Death 79 Male 121 lb 2/11/2011 Physician Australia
Primary
Concomitant
Lung Disorder Other Serious 9/21/2010 72 Male 2/18/2011 Italy
Primary
Secondary
Concomitant
Glomerular Filtration Rate Decreased Other Serious 1/3/2011 69 Male 2/18/2011 Physician Sweden
Primary
Concomitant
Intervertebral Disc Degeneration Hospitalization 5/7/2005 58 Male 174 lb 2/18/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Oedema Peripheral Other Serious 5/19/2008 78 Male 2/25/2011 Consumer United States
Primary
Concomitant
Renal Failure Acute Hospitalization 11/25/2010 79 Male 3/1/2011 Physician Italy
Primary
Concomitant
Acute Respiratory Distress Syndrome Hospitalization 1/13/2011 74 Male 3/1/2011 Physician United States
Primary
Concomitant
Cholestasis Other Serious 1/24/2011 58 Male 3/1/2011 Pharmacist Netherlands
Primary
Secondary
Concomitant
Syncope Other Serious 11/1/2010 77 Male 3/18/2011 Physician Germany
Primary
Concomitant
Cardioactive Drug Level Increased Other Serious 1/1/2009 71 Female 207 lb 3/21/2011 Consumer Germany
Primary
Secondary
Concomitant
Cholestasis Other Serious 1/24/2011 58 Male 3/7/2011 Pharmacist
Primary
Secondary
Concomitant
Vomiting Hospitalization 1/1/2010 89 Female 3/29/2011 Other Health Professional Spain
Primary
Concomitant
Interacting
Syncope Life Threatening 3/6/2011 61 Female 157 lb 4/4/2011 Physician Germany
Primary
Secondary
Concomitant
Herpes Simplex Serology Positive Other Serious 5/7/2005 58 Male 174 lb 4/5/2011 Lawyer United States
Primary
Secondary
Concomitant

Drug Data