Allopurinol combined with Enalapril Maleate

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Death Death 7/10/2005 91 Male 154 lb 1/5/2006 Pharmacist Germany
Primary
Concomitant
Renal Impairment Disability 12/10/2005 80 Male 126 lb 1/12/2006 Physician Japan
Primary
Concomitant
Death Death 7/10/2005 91 Male 154 lb 1/13/2006 Pharmacist Germany
Primary
Concomitant
Pneumonia Death 7/10/2005 91 Male 154 lb 1/25/2006 Other Health Professional Germany
Primary
Concomitant
Pneumonia Death 7/10/2005 91 Male 154 lb 1/31/2006 Other Health Professional Germany
Primary
Concomitant
Pseudoaldosteronism Hospitalization 1/1/2005 63 Male 150 lb 2/17/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Transient Ischaemic Attack Other Serious 1/4/2004 82 Male 170 lb 2/21/2006 Physician United States
Primary
Concomitant
Multiple Myeloma Hospitalization 9/1/1997 69 Male 2/14/2006 Japan
Primary
Concomitant
Transient Ischaemic Attack Death 10/1/2005 72 Female 108 lb 2/27/2006 Lawyer United States
Primary
Concomitant
Systemic Inflammatory Response Syndrome Life Threatening 1/5/2006 65 Male 176 lb 2/22/2006 Physician Germany
Primary
Concomitant
Pneumonia Hospitalization 6/24/2005 91 Male 154 lb 2/22/2006 Other Health Professional Germany
Primary
Concomitant
Oral Intake Reduced Other Serious 1/1/2006 78 Male 168 lb 2/22/2006 United States
Primary
Concomitant
Vomiting Hospitalization 2/6/2006 59 Male 128 lb 2/23/2006 Physician Germany
Primary
Secondary
Concomitant
Tumour Lysis Syndrome Hospitalization 2/14/2006 68 Female 168 lb 3/3/2006 Consumer United States
Primary
Secondary
Concomitant
Red Blood Cell Sedimentation Rate Increased Other Serious 11/12/2005 74 Male 2/24/2006 France
Primary
Secondary
Concomitant
Tumour Lysis Syndrome Hospitalization 2/14/2006 68 Female 168 lb 3/13/2006 Consumer United States
Primary
Secondary
Concomitant
Renal Failure Other Serious 10/31/2002 63 Male 161 lb 3/20/2006 Lawyer United States
Primary
Concomitant
Renal Impairment Required Intervention 10/7/2005 65 Male 3/8/2006 United Kingdom
Primary
Concomitant
Odynophagia Hospitalization 1/15/2006 71 Male 3/10/2006 Physician Japan
Primary
Secondary
Angioneurotic Oedema Hospitalization 1/15/2006 71 Male 3/17/2006 Physician Japan
Primary
Secondary
Tumour Lysis Syndrome Hospitalization 2/14/2006 68 Female 168 lb 3/24/2006 Consumer United States
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 76 Female 130 lb 3/24/2006 Physician Canada
Primary
Concomitant
Interacting
Renal Failure Life Threatening 1/23/2006 Male 192 lb 3/24/2006 Physician Germany
Primary
Concomitant
Gallbladder Pain Other Serious 3/14/2006 65 Male 3/25/2006 Consumer Mexico
Primary
Concomitant
Renal Failure Acute Hospitalization 10/31/2002 63 Male 161 lb 3/27/2006 Physician United States
Primary
Concomitant
Renal Failure Acute Hospitalization 10/31/2002 63 Male 161 lb 4/4/2006 Physician United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 12/22/2005 76 Female 190 lb 3/30/2006 Other Health Professional Germany
Primary
Concomitant
Vomiting Hospitalization 2/6/2006 59 Male 128 lb 3/30/2006 Physician Germany
Primary
Secondary
Concomitant
Tumour Lysis Syndrome Hospitalization 2/14/2006 68 Female 168 lb 4/6/2006 Consumer United States
Primary
Secondary
Concomitant
Thrombocytopenic Purpura Life Threatening 12/27/2005 33 Male 4/4/2006 Argentina
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 1/15/2006 71 Male 4/3/2006 Physician Japan
Primary
Secondary
Rhabdomyolysis Hospitalization 76 Female 130 lb 4/12/2006 Physician Canada
Primary
Concomitant
Interacting
Sepsis Hospitalization 2/6/2006 59 Male 128 lb 4/5/2006 Physician Germany
Primary
Secondary
Concomitant
Gamma-glutamyltransferase Increased Other Serious 12/12/2005 Female 127 lb 4/18/2006 Physician Spain
Primary
Concomitant
Azotaemia Hospitalization 3/20/2006 34 Female 4/12/2006 Mexico
Primary
Concomitant
Post Procedural Complication Other Serious 9/1/2004 56 Male 245 lb 4/24/2006 United States
Primary
Secondary
Concomitant
Tachycardia Hospitalization 5/7/2003 64 Female 205 lb 4/24/2006 Physician United States
Primary
Concomitant
Vomiting Hospitalization 2/6/2006 59 Male 128 lb 4/18/2006 Other Health Professional Germany
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 12/1/2005 85 Male 4/19/2006 Physician France
Primary
Secondary
Concomitant
Tumour Lysis Syndrome Hospitalization 2/14/2006 68 Female 168 lb 4/27/2006 Consumer United States
Primary
Secondary
Concomitant
Vascular Dementia Other Serious 1/1/2003 72 Female 108 lb 5/4/2006 Physician United States
Primary
Concomitant
White Blood Cell Count Decreased Death 7/30/2005 66 Male 203 lb 5/3/2006 Other Health Professional Hungary
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Death 7/26/2005 66 Male 203 lb 5/3/2006 Physician Hungary
Primary
Secondary
Concomitant
Tumour Lysis Syndrome Hospitalization 2/14/2006 68 Female 168 lb 5/15/2006 Consumer United States
Primary
Secondary
Concomitant
Ulcer Haemorrhage Hospitalization 1/1/2003 55 Male 251 lb 5/18/2006 Lawyer United States
Primary
Concomitant
Fibrosis Other Serious 3/20/2006 34 Female 6/5/2006 Other Health Professional Mexico
Primary
Concomitant
Stomatitis Hospitalization 3/13/2006 Female 6/15/2006 Physician Japan
Primary
Concomitant
Tumour Lysis Syndrome Hospitalization 5/10/2005 44 Female 101 lb 6/20/2006 Physician Argentina
Primary
Secondary
Concomitant
Rash Required Intervention 5/15/2006 57 Male 246 lb 6/27/2006 Pharmacist United States
Primary
Concomitant
Renal Failure Acute Hospitalization 6/9/2006 56 Male 205 lb 6/23/2006 Physician Brazil
Primary
Concomitant
Renal Failure Acute Hospitalization 6/9/2006 56 Male 205 lb 7/5/2006 Physician Brazil
Primary
Concomitant
Pharmaceutical Product Complaint Other Serious 3/2/2006 59 Male 215 lb 6/29/2006 Pharmacist United States
Primary
Concomitant
Hypoglycaemia Hospitalization 4/14/2006 76 Male 7/11/2006 Sweden
Primary
Secondary
Concomitant
Nephritis Interstitial Disability 5/5/2006 61 Male 7/11/2006 Physician Japan
Primary
Secondary
Nephritis Interstitial Disability 5/5/2006 61 Male 7/11/2006 Physician Japan
Primary
Secondary
Blood Glucose Increased 41 Male 7/21/2006 Consumer United States
Primary
Concomitant
Nephritis Interstitial Disability 5/5/2006 61 Male 7/21/2006 Physician Japan
Primary
Secondary
Concomitant
Pneumonia Hospitalization 3/1/2005 70 Male 179 lb 7/20/2006 Physician South Africa
Primary
Concomitant
Rhabdomyolysis Other Serious Male 7/31/2006 Physician France
Primary
Concomitant
Urinary Bladder Haemorrhage Required Intervention 6/19/2006 69 Male 7/18/2006 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2006 67 Female 7/28/2006 Pharmacist Germany
Primary
Concomitant
Syncope Other Serious 12/26/2005 59 Male 7/28/2006 Physician Switzerland
Primary
Concomitant
Therapeutic Response Decreased Female 205 lb 8/8/2006 Other Health Professional United States
Primary
Concomitant
Therapeutic Response Decreased 11/7/2005 74 Female 8/9/2006 Physician United States
Primary
Concomitant
Restrictive Pulmonary Disease Hospitalization 3/27/2006 72 Male 198 lb 8/14/2006 Physician Germany
Primary
Concomitant
Sepsis Hospitalization 7/20/2006 56 Male 203 lb 8/10/2006 Physician Brazil
Primary
Concomitant
Weight Increased Other Serious 69 Male 175 lb 7/19/2006 United States
Primary
Concomitant
Sepsis Hospitalization 7/20/2006 56 Male 203 lb 8/22/2006 Physician Brazil
Primary
Concomitant
Renal Failure Acute Hospitalization 5/5/2006 Female 8/30/2006 Consumer Japan
Primary
Secondary
Concomitant
Visual Acuity Reduced Other Serious 1/1/2000 52 Female 143 lb 8/25/2006
Primary
Secondary
Concomitant
Tenderness Life Threatening 7/11/2006 75 Male 9/6/2006 Pharmacist United States
Primary
Concomitant
Sepsis Hospitalization 7/18/2006 56 Male 203 lb 9/1/2006 Brazil
Primary
Concomitant
Drug Interaction Other Serious 7/22/2006 74 Male 9/1/2006 Pharmacist Japan
Primary
Secondary
Concomitant
Sepsis Hospitalization 7/18/2006 56 Male 203 lb 9/1/2006 Brazil
Primary
Concomitant
Drug Interaction Other Serious 7/22/2006 74 Male 9/1/2006 Pharmacist Japan
Primary
Secondary
Concomitant
Neck Pain Other Serious 52 Female 143 lb 9/7/2006 Physician Austria
Primary
Concomitant
Yellow Skin Hospitalization 8/27/2006 69 Male 9/8/2006 Physician Austria
Primary
Concomitant
Thrombocytopenia Hospitalization 8/28/2006 70 Male 9/3/2006 Physician Germany
Primary
Concomitant
Rhinorrhoea Hospitalization 8/8/2006 60 Male 234 lb 9/12/2006 Other Health Professional Poland
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 7/18/2006 56 Male 203 lb 9/18/2006 Other Health Professional Brazil
Primary
Concomitant
Ocular Icterus Hospitalization 9/7/2006 48 Male 9/26/2006 Physician Germany
Primary
Concomitant
Platelet Count Decreased Hospitalization 9/7/2006 74 Male 121 lb 9/21/2006 Japan
Primary
Concomitant
Weight Decreased Other Serious 1/1/2006 71 Male 225 lb 9/22/2006 Consumer United States
Primary
Concomitant
Ocular Icterus Hospitalization 9/1/2006 48 Male 9/29/2006 Physician Germany
Primary
Concomitant
Yellow Skin Hospitalization 8/27/2006 69 Male 9/28/2006 Physician Austria
Primary
Concomitant
Thrombocytopenia Other Serious 7/18/2006 56 Male 203 lb 9/27/2006 Other Health Professional Brazil
Primary
Concomitant
Vomiting Hospitalization 2/7/2006 59 Male 128 lb 9/27/2006 Physician Germany
Primary
Secondary
Concomitant
Platelet Count Decreased Hospitalization 9/7/2006 74 Male 121 lb 10/3/2006 Physician Japan
Primary
Concomitant
Weight Increased Other Serious 8/1/2006 Male 152 lb 10/12/2006 Physician Spain
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 11/15/2005 Male 10/12/2006 Other Health Professional France
Primary
Concomitant
Thrombocytopenia Other Serious 7/18/2006 56 Male 203 lb 10/10/2006 Other Health Professional Brazil
Primary
Concomitant
White Blood Cell Count Increased Death 8/1/2006 64 Female 140 lb 10/12/2006 Physician Japan
Primary
Concomitant
Electrocardiogram Change Other Serious 10/6/2006 76 Female 168 lb 10/23/2006
Primary
Concomitant
Renal Failure Acute Hospitalization 9/23/2006 59 Male 10/26/2006 United States
Primary
Secondary
Concomitant
Treatment Noncompliance Life Threatening 1/23/2006 71 Male 187 lb 11/1/2006 Physician Germany
Primary
Concomitant
Electrocardiogram Change Other Serious 10/6/2006 76 Female 168 lb 11/2/2006
Primary
Concomitant
Cerebral Infarction Hospitalization 2/22/2006 73 Female 192 lb 11/6/2006
Primary
Concomitant
Cerebral Infarction Hospitalization 2/22/2006 73 Female 192 lb 11/14/2006
Primary
Concomitant
Renal Failure Acute Required Intervention 10/11/2006 77 Male 154 lb 11/6/2006 Germany
Primary
Concomitant
Platelet Count Decreased Hospitalization 9/7/2006 74 Male 121 lb 11/9/2006 Physician Japan
Primary
Concomitant
Weight Decreased Other Serious 1/1/2006 71 Male 243 lb 11/20/2006 Physician United States
Primary
Concomitant
Renal Failure Other Serious 10/31/2006 Male 12/1/2006 Physician Spain
Primary
Concomitant
Prothrombin Time Prolonged Other Serious 3/1/2006 72 Male 12/12/2006 Physician Argentina
Primary
Concomitant
Thrombocytopenia Other Serious 7/18/2006 56 Male 203 lb 12/13/2006 Other Health Professional Brazil
Primary
Concomitant
Urine Output Decreased Hospitalization 11/18/2006 62 Male 187 lb 1/3/2007 Physician Spain
Primary
Secondary
Stevens-johnson Syndrome Death 10/1/2003 62 Male 200 lb 10/20/2006 Other Health Professional United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 12/4/2006 71 Male 1/17/2007 Physician Japan
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Life Threatening 11/20/2005 73 Male 10/10/2006 Physician United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 12/4/2006 71 Male 1/25/2007 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 12/4/2006 71 Male 2/5/2007 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 12/4/2006 71 Male 2/12/2007 Physician Japan
Primary
Secondary
Concomitant
Orthopnoea Hospitalization 1/1/2007 62 Male 159 lb 3/7/2007 Physician Switzerland
Primary
Concomitant
Septic Shock Hospitalization 11/18/2006 62 NotSpecified 187 lb 3/6/2007 Physician Spain
Primary
Secondary
White Blood Cell Count Decreased Other Serious 12/4/2006 71 Male 2/28/2007 Physician Japan
Primary
Secondary
Concomitant
Pneumonia Life Threatening 5/2/2001 65 Male 104 lb 3/12/2007 Other Health Professional France
Primary
Concomitant
Visual Acuity Reduced Other Serious 1/1/1997 52 Female 143 lb 3/13/2007 Physician Austria
Primary
Concomitant
Paraesthesia Other Serious 8/1/2006 67 Male 220 lb 11/28/2006 United States
Primary
Concomitant
Vertigo Other Serious 2/21/2007 87 Male 228 lb 2/28/2007 Pharmacist United States
Primary
Concomitant
Small Intestinal Obstruction Hospitalization 2/1/2007 65 Male 222 lb 4/2/2007 Physician United States
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 7/21/2006 Male 203 lb 4/2/2007 Brazil
Primary
Concomitant
Gastric Ulcer Hospitalization 3/15/2007 70 Female 4/9/2007 Other Health Professional Austria
Primary
Secondary
Concomitant
Gastric Ulcer Haemorrhage Hospitalization 3/15/2007 70 Female 4/13/2007 Other Health Professional Austria
Primary
Secondary
Concomitant
Gastric Ulcer Haemorrhage Hospitalization 3/15/2007 70 Female 4/13/2007 Other Health Professional Austria
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 7/18/2006 Male 203 lb 4/13/2007 Brazil
Primary
Concomitant
Myelodysplastic Syndrome Disability 1/1/2007 Male 137 lb 4/17/2007 Physician Belgium
Primary
Concomitant
Vomiting 9/8/2006 58 Female 1/25/2007 Consumer United States
Primary
Concomitant
Rectal Haemorrhage Life Threatening 3/14/2007 79 Male 5/8/2007 Pharmacist United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 12/4/2006 71 Male 5/18/2007 Physician Japan
Primary
Concomitant
Azotaemia Other Serious 5/18/2007 Female 133 lb 5/30/2007 Physician Mexico
Primary
Concomitant
Pulmonary Mass Other Serious 12/4/2006 71 Male 5/24/2007 Physician Japan
Primary
Concomitant
Intestinal Haemorrhage Hospitalization 5/3/2007 70 Female 115 lb 5/31/2007 Consumer Brazil
Primary
Concomitant
Azotaemia Other Serious 5/18/2007 Female 133 lb 6/14/2007 Physician Mexico
Primary
Concomitant
Aplasia Pure Red Cell Disability 1/1/2007 Male 137 lb 6/18/2007 Physician Belgium
Primary
Secondary
Concomitant
Pneumonitis Other Serious 12/9/2006 60 Male 4/24/2007 Physician United States
Primary
Concomitant
Thrombocytopenia Hospitalization 7/18/2006 Male 203 lb 6/28/2007 Brazil
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 12/4/2006 71 Male 6/28/2007 Physician Japan
Primary
Concomitant
Electrocardiogram Change Other Serious 10/6/2006 76 Female 168 lb 7/11/2007
Primary
Secondary
Concomitant
Peritonitis Hospitalization 5/31/2007 Female 7/12/2007 Consumer United States
Primary
Concomitant
Pneumonia Other Serious 6/12/2007 Male 7/11/2007 Physician Germany
Primary
Concomitant
Haemoptysis Other Serious 7/27/2005 Male 203 lb 7/13/2007 Consumer Hungary
Primary
Secondary
Concomitant
Vomiting Other Serious 1/1/2006 Female 106 lb 7/19/2007 Physician Japan
Primary
Secondary
Concomitant
Peritonitis Life Threatening 10/7/2006 72 Female 78 lb 7/20/2007 Physician Japan
Primary
Secondary
Concomitant
Encephalopathy Life Threatening 6/2/2007 73 Male 7/31/2007 Other Health Professional Japan
Primary
Concomitant
Sepsis Hospitalization 6/4/2007 60 Female 7/30/2007 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 72 Male 8/7/2007 Consumer United States
Primary
Concomitant
Tendonitis Hospitalization 3/22/2005 Male 154 lb 8/9/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Myocardial Infarction Death 5/28/2007 77 Male 8/10/2007 Physician Sweden
Primary
Concomitant
Complications Of Transplant Surgery Other Serious 5/18/2007 Female 133 lb 8/10/2007 Physician Mexico
Primary
Concomitant
Thrombocytopenia 6/21/2007 63 Male 8/10/2007 France
Primary
Secondary
Concomitant
Large Intestine Perforation Life Threatening 10/7/2006 72 Female 78 lb 8/13/2007 Physician Japan
Primary
Secondary
Concomitant

Drug Data