Allopurinol combined with Doxorubicin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
White Blood Cell Count Decreased Hospitalization 6/5/2006 70 Female 239 lb 6/30/2006 Physician United States
Primary
Secondary
Concomitant
Pyrexia Other Serious 68 Male 2/12/2008 Other Health Professional Japan
Primary
Concomitant
Renal Failure Death 3/12/2008 74 Female 123 lb 7/24/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Febrile Neutropenia Life Threatening 12/28/2008 Male 2/2/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Neuropathy Peripheral Life Threatening 6/24/2008 Male 11/19/2009 Physician India
Primary
Concomitant
Small Intestinal Obstruction Hospitalization 5/11/2009 Male 247 lb 12/15/2009 Physician Australia
Primary
Secondary
Concomitant
Weight Decreased Other Serious 3/14/1999 Male 2/18/2010 Physician United States
Primary
Secondary
Concomitant
Cardiac Disorder Hospitalization 1/21/2010 Male 172 lb 2/19/2010 Physician
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2005 Female 2/23/2010 Other Health Professional United States
Primary
Concomitant
Weight Decreased Other Serious 3/14/1999 Male 3/5/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Interstitial Lung Disease Other Serious 9/16/1998 66 Female 3/5/2010 Consumer Canada
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2005 Female 3/8/2010 Other Health Professional United States
Primary
Concomitant
Febrile Neutropenia Hospitalization 11/2/2009 Male 230 lb 3/9/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Death Death 1/17/2010 Male 133 lb 3/17/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Neutropenia Hospitalization 1/22/2010 Male 243 lb 3/18/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Tachycardia Other Serious 6/16/2005 Female 3/18/2010 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2005 Female 3/18/2010 Other Health Professional United States
Primary
Concomitant
Weight Decreased Other Serious 3/14/1999 Male 3/19/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Tachycardia Other Serious 6/16/2005 28 Female 7/1/2010 United States
Primary
Concomitant
Pneumonia Hospitalization 9/30/2010 10/28/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Neutropenia Life Threatening 7/20/2009 68 Female 150 lb 12/1/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Progressive Multifocal Leukoencephalopathy Hospitalization 5/1/2010 72 Female 12/9/2010 Other Health Professional Sweden
Primary
Secondary
Concomitant
Splenomegaly Other Serious 4/4/2008 67 Male 268 lb 12/16/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Splenomegaly Hospitalization 5/30/2008 67 Male 12/16/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Diarrhoea Hospitalization 11/13/2010 77 Female 93 lb 12/22/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Dehydration Hospitalization 11/13/2010 72 Female 108 lb 1/6/2011 Consumer United Kingdom
Primary
Secondary
Concomitant
Respiratory Failure Death 7/9/2009 76 Male 187 lb 1/6/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Infection Hospitalization 10/16/2009 1/20/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Haematuria Hospitalization 10/16/2009 1/24/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Anaemia Hospitalization 11/13/2010 72 Female 108 lb 1/28/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Heart Rate Increased Hospitalization 1/1/2007 61 Male 2/28/2011 Consumer United States
Primary
Concomitant
Constipation Hospitalization 2/15/2011 3/7/2011 Physician United Kingdom
Primary
Secondary
Blood Pressure Abnormal Other Serious 2/1/2011 54 Male 3/8/2011 Other Health Professional United States
Primary
Concomitant
Atrial Fibrillation Hospitalization 12/5/2010 3/10/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Toxicity To Various Agents Hospitalization 2/20/2011 3/10/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Toxicity To Various Agents Hospitalization 2/20/2011 67 Female 116 lb 3/11/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Haemoglobin Decreased Other Serious 2/1/2011 54 Male 3/28/2011 Other Health Professional United States
Primary
Concomitant
Nausea Hospitalization 2/20/2011 3/30/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Atrial Fibrillation Hospitalization 12/5/2010 3/31/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Infection Hospitalization 10/16/2009 3/31/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Febrile Neutropenia Other Serious 10/1/2001 28 Female 4/5/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Cyst Hospitalization 1/1/2007 61 Male 4/13/2011 Consumer United States
Primary
Concomitant
Nausea Other Serious 28 Female 4/21/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Febrile Neutropenia Life Threatening 10/6/2010 72 Female 143 lb 4/29/2011 Consumer United Kingdom
Primary
Secondary
Concomitant
Metabolic Acidosis Death 34 Female 3/27/2012 Physician United Kingdom
Primary
Concomitant
Renal Failure Acute Death 1/1/2009 34 Female 5/9/2012 Physician United Kingdom
Primary
Concomitant
Metabolic Acidosis Death 51 Male 8/16/2012 Physician Japan
Primary
Secondary
Progressive Multifocal Leukoencephalopathy Death 8/15/2011 53 Female 209 lb 10/17/2013 Physician Gb
Primary
Secondary
Concomitant
Oral Candidiasis Hospitalization 3/18/2010 13 Male 119 lb 6/24/2013 Physician Nl
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 11/22/2011 63 Female 110 lb 3/18/2013 Physician It
Primary
Secondary
Concomitant
Respiratory Tract Infection Hospitalization 12/31/2011 65 Female 122 lb 10/18/2012 Country Not Specified
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 4/10/2012 71 Female 87 lb 4/23/2013 Physician Ua
Primary
Secondary
Concomitant
Gastric Haemorrhage Hospitalization 5/30/2012 63 Male 115 lb 3/8/2013 Physician Jp
Primary
Secondary
Concomitant
Pneumonia Other Serious 4/19/2012 67 Male 176 lb 10/9/2012 Country Not Specified
Primary
Secondary
Concomitant
Pneumonia Hospitalization 4/23/2012 70 Male 168 lb 11/8/2012 Physician De
Primary
Secondary
Concomitant
Vomiting Hospitalization 6/6/2012 NotSpecified 8/22/2013 Physician Gb
Primary
Secondary
Concomitant
Tumour Lysis Syndrome Other Serious 51 Male 127 lb 9/21/2012 Other Health Professional Jp
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 12/21/2011 70 Female 194 lb 10/3/2012 Other Health Professional Us
Primary
Secondary
Concomitant
Subarachnoid Haemorrhage Hospitalization 11/24/2010 56 Male 143 lb 7/4/2013 Physician De
Primary
Secondary
Concomitant
Neutropenia Hospitalization 8/3/2012 Female 2/22/2013 Physician De
Primary
Secondary
Concomitant
Nausea Hospitalization 4/24/2012 78 Female 9/14/2012 Physician De
Primary
Secondary
Concomitant
Vomiting Other Serious 7/9/2012 Female 9/20/2012 Country Not Specified
Primary
Secondary
Concomitant
Vomiting Hospitalization 7/9/2012 Female 7/18/2013 Physician De
Primary
Secondary
Concomitant
Sepsis Other Serious 9/24/2012 Other Health Professional Country Not Specified
Primary
Secondary
Concomitant
Liver Disorder Hospitalization 9/14/2012 63 Male 110 lb 10/9/2012 Physician Jp
Primary
Secondary
Concomitant
Sinus Tachycardia Hospitalization 9/14/2012 61 Male 150 lb 12/26/2012 Consumer Us
Primary
Secondary
Concomitant
Neutropenic Sepsis Life Threatening 12/22/2011 71 Male 201 lb 2/25/2013 Physician Gb
Primary
Secondary
Concomitant
Neutropenia Other Serious 3/23/2012 58 Female 220 lb 6/12/2013 Physician Gb
Primary
Secondary
Concomitant
Stomatitis Hospitalization 9/2006 Female 10/10/2012 Physician Es
Primary
Secondary
Concomitant
Thrombosis Other Serious 9/28/2012 Male 12/12/2012 Pharmacist De
Primary
Secondary
Concomitant
Small Intestinal Obstruction Hospitalization 5/6/2012 47 Female 148 lb 12/28/2012 Physician Fr
Primary
Secondary
Concomitant
Infection Hospitalization 2/14/2012 Male 10/19/2012 Physician De
Primary
Secondary
Concomitant
Pyrexia Hospitalization 9/16/2012 Male 10/21/2012 Physician De
Primary
Secondary
Concomitant
Gastric Haemorrhage Other Serious 5/30/2012 63 Male 115 lb 3/20/2013 Physician Jp
Primary
Secondary
Concomitant
Pleural Effusion Hospitalization 9/20/2012 57 Female 11/9/2012 Pharmacist Gb
Primary
Concomitant
Lower Respiratory Tract Infection Hospitalization 2/28/2012 52 Female 151 lb 12/4/2012 Physician Gb
Primary
Secondary
Concomitant
Pyrexia Hospitalization 9/16/2012 Male 11/7/2012 Physician Us
Primary
Secondary
Concomitant
Respiratory Failure Disability 7/13/2012 59 Female 12/20/2012 Physician Gb
Primary
Secondary
Concomitant
Small Intestinal Obstruction Hospitalization 5/6/2012 47 Female 148 lb 11/13/2012 Physician Fr
Primary
Secondary
Concomitant
Pneumonia Hospitalization 4/23/2012 70 Male 168 lb 11/15/2012 Physician De
Primary
Secondary
Concomitant
Mitral Valve Disease Hospitalization 11/8/2012 Female 3/28/2013 Physician De
Primary
Secondary
Concomitant
Renal Failure Hospitalization 11/19/2012 60 Female 295 lb 12/27/2012 Physician Us
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 12/11/2011 78 Male 159 lb 12/12/2012 Other Health Professional Gb
Primary
Secondary
Concomitant
Diarrhoea Hospitalization 2/7/2011 75 Female 12/17/2012 Physician Be
Primary
Secondary
Concomitant
Anaphylactic Reaction Hospitalization 11/29/2012 49 Male 172 lb 1/24/2013 Consumer Nl
Primary
Secondary
Concomitant
Pyrexia Hospitalization 9/16/2010 46 Female 132 lb 12/17/2012 Physician Nl
Primary
Secondary
Respiratory Failure Hospitalization 7/13/2012 59 Female 218 lb 12/18/2012 Other Health Professional Gb
Primary
Secondary
Concomitant
Diarrhoea Hospitalization 2/7/2011 75 Female 12/26/2012 Physician Be
Primary
Secondary
Concomitant
Epistaxis Hospitalization 11/14/2009 64 Male 12/26/2012 Other Health Professional Gb
Primary
Secondary
Concomitant
Respiratory Failure Disability 7/13/2012 59 Female 218 lb 12/27/2012 Other Health Professional Gb
Primary
Secondary
Concomitant
Pneumocystis Jirovecii Pneumonia Hospitalization 11/27/2012 63 Male 196 lb 4/18/2013 Physician Jp
Primary
Secondary
Concomitant
Epistaxis Hospitalization 11/14/2009 64 Male 1/4/2013 Other Health Professional Gb
Primary
Secondary
Concomitant
Epistaxis Hospitalization 11/14/2009 64 Male 1/3/2013 Physician Gb
Primary
Secondary
Concomitant
Syncope Death 1/3/2013 70 Male 264 lb 2/15/2013 Other Health Professional Us
Primary
Secondary
Concomitant
Pneumonia Hospitalization 12/28/2012 77 Female 93 lb 3/6/2013 Physician Jp
Primary
Secondary
Concomitant
Thrombocytopenia Death 1/3/2013 70 Male 264 lb 1/8/2013 Other Health Professional Us
Primary
Secondary
Concomitant
Neutropenia Other Serious 11/13/2012 Female 1/28/2013 Physician De
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 12/3/2012 56 Male 198 lb 1/22/2013 Other Health Professional Gb
Primary
Secondary
Concomitant
Hypotension Hospitalization 1/9/2013 71 Male 152 lb 6/21/2013 Physician It
Primary
Secondary
Concomitant
Pneumonia Hospitalization 1/24/2013 Male 174 lb 3/1/2013 Physician It
Primary
Secondary
Concomitant
Oral Candidiasis Hospitalization 11/30/2012 73 Male 174 lb 7/5/2013 Physician It
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 2/15/2013 64 Female 110 lb 4/16/2013 Physician De
Primary
Secondary
Concomitant
Blood Creatinine Increased Hospitalization 10/23/2012 Female 1/21/2013 Physician De
Primary
Secondary
Concomitant
Plasmacytoma Hospitalization 11/25/2012 73 Male 181 lb 5/21/2013 Other Health Professional Us
Primary
Secondary
Concomitant
Lung Infection Hospitalization 2/19/2013 NotSpecified 5/1/2013 Physician Gb
Primary
Secondary
Concomitant
Thrombocytopenia Death 9/12/2012 82 Female 148 lb 5/17/2013 Physician De
Primary
Secondary
Concomitant
Circulatory Collapse Hospitalization 2/18/2013 71 Female 3/25/2013 Other Health Professional De
Primary
Secondary
Concomitant
Circulatory Collapse Hospitalization 2/18/2013 71 Female 4/23/2013 Physician De
Primary
Secondary
Concomitant
Lower Respiratory Tract Infection Hospitalization 2/2/2013 66 Female 3/20/2013 Other Health Professional Gb
Primary
Secondary
Concomitant
Transfusion Reaction Hospitalization 9/2/2011 10/30/2012 Other Health Professional Gb
Primary
Secondary
Concomitant
Death Death NotSpecified 3/29/2013 Physician Us
Primary
Secondary
Concomitant
Tumour Lysis Syndrome Hospitalization 12/29/2012 76 Male 4/1/2013 Physician Fr
Primary
Secondary
Concomitant
Mitral Valve Disease Hospitalization 11/8/2012 Female 4/1/2013 Physician De
Primary
Secondary
Concomitant
General Physical Health Deterioration Hospitalization 4/11/2013 Male 4/29/2013 Physician De
Primary
Secondary
Concomitant
Eosinophilia Hospitalization 3/28/2013 72 Male 201 lb 5/14/2013 Physician Gr
Primary
Secondary
Concomitant
Syncope Hospitalization 3/24/2013 Male 6/17/2013 Physician De
Primary
Secondary
Concomitant
Pneumonia Hospitalization 4/1/2013 66 Female 132 lb 8/21/2013 Other Health Professional Gb
Primary
Secondary
Concomitant
General Physical Health Deterioration Hospitalization 4/1/2013 59 Female 206 lb 5/10/2013 Physician De
Primary
Secondary
Concomitant
Pneumonia Hospitalization 2/19/2012 57 Female 150 lb 5/16/2013 Physician Hu
Primary
Secondary
Concomitant
Lower Respiratory Tract Infection Hospitalization 3/31/2013 65 Female 132 lb 5/24/2013 Consumer Gb
Primary
Secondary
Concomitant
Off Label Use Other Serious 6/29/2010 50 Male 165 lb 5/28/2013 Physician Pt
Primary
Secondary
Concomitant
Respiratory Disorder Hospitalization 10/26/2012 68 Male 5/29/2013 Consumer Se
Primary
Secondary
Concomitant
Tachycardia Required Intervention 5/22/2013 82 NotSpecified 5/24/2013 Other Health Professional Us
Primary
Secondary
Concomitant
Tachycardia Required Intervention 5/22/2013 82 Female 199 lb 5/28/2013 Other Health Professional Us
Primary
Secondary
Concomitant
Proteinuria Hospitalization 7/13/2012 39 Female 137 lb 5/30/2013 Physician Ua
Primary
Secondary
Concomitant
Neutropenic Sepsis Hospitalization 4/18/2013 NotSpecified 7/2/2013 Physician Gb
Primary
Secondary
Concomitant
Peripheral Sensory Neuropathy Other Serious 47 Female 6/7/2013 Physician Ch
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 10/21/2011 49 Female 129 lb 6/13/2013 Physician Ua
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 7/13/2012 59 Female 220 lb 6/14/2013 Other Health Professional Gb
Primary
Secondary
Concomitant
Intestinal Perforation Life Threatening 6/10/2013 63 Male 7/29/2013 Physician Jp
Primary
Secondary
Concomitant
Gastric Perforation Hospitalization 6/2/2013 54 Female 6/14/2013 Physician Hu
Primary
Secondary
Concomitant
Multi-organ Failure Life Threatening NotSpecified 6/18/2013 Physician Gb
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 5/31/2013 67 Female 7/24/2013 Physician Gb
Primary
Secondary
Concomitant
Renal Failure Life Threatening NotSpecified 6/18/2013 Physician Gb
Primary
Secondary
Concomitant
Colitis Hospitalization 6/7/2013 53 Female 7/19/2013 Physician Jp
Primary
Secondary
Concomitant
Lung Adenocarcinoma Other Serious 4/16/2013 63 Female 6/19/2013 Physician Hu
Primary
Secondary
Concomitant
Stomatitis Hospitalization 3/7/2013 77 Male 212 lb 8/6/2013 Physician Us
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 5/31/2013 67 Female 7/26/2013 Physician Gb
Primary
Secondary
Concomitant
Off Label Use Death NotSpecified 6/24/2013 Physician Us
Primary
Secondary
Concomitant
Off Label Use Other Serious NotSpecified 6/25/2013 Physician Us
Primary
Secondary
Concomitant
Ventriculo-peritoneal Shunt Other Serious NotSpecified 7/9/2013 Physician Us
Primary
Secondary
Concomitant
Wrong Technique In Drug Usage Process Death NotSpecified 6/26/2013 Physician Us
Primary
Secondary
Concomitant
Wrong Technique In Drug Usage Process Other Serious NotSpecified 6/26/2013 Physician Us
Primary
Secondary
Concomitant
Wrong Technique In Drug Usage Process Other Serious NotSpecified 6/26/2013 Physician Us
Primary
Secondary
Concomitant
Wrong Technique In Drug Usage Process Other Serious NotSpecified 6/26/2013 Physician Us
Primary
Secondary
Concomitant
Wrong Technique In Drug Usage Process Other Serious NotSpecified 6/26/2013 Physician Us
Primary
Secondary
Concomitant
Wrong Technique In Drug Usage Process Other Serious NotSpecified 6/26/2013 Physician Us
Primary
Secondary
Concomitant
Herpes Simplex Hepatitis Death 6/2/2013 63 Female 7/5/2013 Physician Nl
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 5/31/2013 67 Female 8/7/2013 Physician Gb
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 5/31/2013 67 Female 7/30/2013 Physician Gb
Primary
Secondary
Concomitant

Drug Data