Allopurinol combined with Diltiazem

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Death Other Serious 12/25/2004 74 Male 1/20/2006 Pharmacist United States
Primary
Concomitant
Urine Output Decreased Hospitalization 81 Male 2/7/2006 Pharmacist United States
Primary
Secondary
Odynophagia Hospitalization 1/15/2006 71 Male 3/10/2006 Physician Japan
Primary
Secondary
Angioneurotic Oedema Hospitalization 1/15/2006 71 Male 3/17/2006 Physician Japan
Primary
Secondary
Weight Decreased Hospitalization 3/19/2006 70 Male 166 lb 3/24/2006 Pharmacist United States
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 1/15/2006 71 Male 4/3/2006 Physician Japan
Primary
Secondary
White Blood Cell Count Abnormal Other Serious 2/24/2006 Female 4/13/2006 Physician United States
Primary
Concomitant
Azotaemia Hospitalization 3/20/2006 34 Female 4/12/2006 Mexico
Primary
Concomitant
Petechiae Required Intervention 4/18/2006 80 Female 176 lb 5/1/2006 Physician United States
Primary
Concomitant
Pulmonary Oedema Required Intervention 5/8/2006 75 Female 144 lb 5/9/2006 Pharmacist United States
Primary
Concomitant
Somnolence Hospitalization 2/14/2006 60 Male 5/11/2006 France
Primary
Secondary
Concomitant
Rash Generalised Life Threatening 2/14/2006 Male 5/16/2006 Pharmacist United States
Primary
Concomitant
Rhabdomyolysis Hospitalization 60 Male 5/23/2006 France
Primary
Concomitant
Interacting
Cerebral Haemorrhage Hospitalization 3/18/2005 48 Female 5/26/2006 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Increased Life Threatening 3/29/2006 72 Male 229 lb 5/31/2006 Pharmacist United States
Primary
Secondary
Concomitant
Ventricular Tachycardia Hospitalization 69 Female 176 lb 6/8/2006 Canada
Primary
Concomitant
Fibrosis Other Serious 3/20/2006 34 Female 6/5/2006 Other Health Professional Mexico
Primary
Concomitant
Toe Amputation Required Intervention 1/1/2006 74 Male 5/30/2006 Physician United States
Primary
Concomitant
Skin Ulcer Required Intervention 5/24/2006 74 Male 5/30/2006 Physician United States
Primary
Concomitant
Stomatitis Other Serious 2/1/2006 68 Male 195 lb 4/24/2006 United States
Primary
Concomitant
Viral Infection Hospitalization 69 Female 176 lb 6/16/2006 Canada
Primary
Concomitant
Interacting
Myalgia 5/2/2006 Male 229 lb 8/16/2006 Pharmacist United States
Primary
Concomitant
Dyskinesia Other Serious 5/1/2006 72 Male 168 lb 7/19/2006 United States
Primary
Concomitant
Bone Pain 3/1/2006 72 Female 271 lb 8/22/2006 United States
Primary
Concomitant
Swelling Face Hospitalization 85 Male 11/10/2006 United Kingdom
Primary
Secondary
Concomitant
Gastrointestinal Ulcer Other Serious Male 8/18/2006 United States
Primary
Concomitant
Ulcer Hospitalization 12/13/2006 79 Female 141 lb 1/19/2007 Pharmacist United States
Primary
Secondary
Concomitant
Peritonitis Hospitalization 11/27/2005 68 Male 212 lb 3/5/2007 Physician United Kingdom
Primary
Concomitant
Visual Acuity Reduced Other Serious 3/29/2007 79 Male 196 lb 5/11/2007 Physician Germany
Primary
Concomitant
Iron Deficiency Other Serious 3/1/2007 Female 5/11/2007 Physician United States
Primary
Concomitant
Serum Ferritin Increased Other Serious 12/5/2006 79 Male 5/23/2007 Physician United States
Primary
Concomitant
Azotaemia Other Serious 5/18/2007 Female 133 lb 5/30/2007 Physician Mexico
Primary
Concomitant
Scleroderma Other Serious 6/1/2005 66 Male 190 lb 6/1/2007 Physician United States
Primary
Concomitant
Azotaemia Other Serious 5/18/2007 Female 133 lb 6/14/2007 Physician Mexico
Primary
Concomitant
Pancytopenia Death 5/29/2007 Female 6/19/2007 Pharmacist United States
Primary
Concomitant
Chronic Obstructive Pulmonary Disease Death Male 6/25/2007 Physician United States
Primary
Concomitant
Pain In Extremity Other Serious 73 Female 6/28/2007 Other Health Professional Germany
Primary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 6/1/2007 Male 284 lb 6/29/2007 Physician United States
Primary
Concomitant
Lip Swelling 1/1/2007 Male 7/26/2007 Pharmacist United States
Primary
Concomitant
Complications Of Transplant Surgery Other Serious 5/18/2007 Female 133 lb 8/10/2007 Physician Mexico
Primary
Concomitant
Blood Creatinine Increased Hospitalization 5/21/2007 Male 5/22/2007 United States
Primary
Concomitant
White Blood Cell Count Decreased Life Threatening 7/19/2007 77 Female 8/30/2007 Physician Canada
Primary
Concomitant
Serum Ferritin Increased Other Serious 12/1/2006 79 Male 187 lb 9/13/2007 Physician United States
Primary
Concomitant
Stomatitis Hospitalization 2/18/2006 59 Male 139 lb 2/18/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Hallucination Other Serious 70 Female 9/20/2007 Other Health Professional Germany
Primary
Secondary
Concomitant
Pulmonary Alveolar Haemorrhage Hospitalization 55 Male 9/26/2007 Other Health Professional United States
Primary
Concomitant
Visual Acuity Reduced Other Serious 1/1/2007 Male 9/26/2007 Consumer Germany
Primary
Concomitant
Liver Function Test Abnormal 4/10/2007 67 Male 8/16/2007 Pharmacist United States
Primary
Concomitant
Pain In Extremity Disability 1/1/2005 73 Female 9/28/2007 Other Health Professional Germany
Primary
Concomitant
Spinal Disorder Hospitalization 1/1/2007 55 Female 238 lb 10/5/2007 Pharmacist France
Primary
Concomitant
Rash Other Serious 10/30/2005 57 Male 10/9/2007 Consumer New Zealand
Primary
Concomitant
Febrile Neutropenia Life Threatening 7/19/2007 77 Male 10/5/2007 Physician Canada
Primary
Concomitant
Left Ventricular Failure Other Serious 9/9/2007 Male 11/6/2007 Physician Australia
Primary
Concomitant
Jaundice Other Serious 10/5/2007 56 Female 227 lb 11/15/2007
Primary
Concomitant
Hepatitis Other Serious 10/5/2007 56 Female 227 lb 11/16/2007 United Kingdom
Primary
Concomitant
Staphylococcal Sepsis Other Serious 1/1/2006 Male 11/28/2007 Lawyer United States
Primary
Secondary
Concomitant
Thrombosis In Device Required Intervention 12/22/2007 68 Male 1/31/2008 Physician United States
Primary
Concomitant
Jaundice Other Serious 10/20/2007 Male 2/8/2008 Other Health Professional France
Primary
Secondary
Concomitant
Respiratory Arrest Hospitalization 1/7/2008 68 Female 210 lb 2/5/2008 Other Health Professional United States
Primary
Concomitant
Febrile Neutropenia Hospitalization 2/5/2008 Male 136 lb 2/6/2008 United States
Primary
Concomitant
Febrile Neutropenia Other Serious 2/5/2008 80 Male 136 lb 2/14/2008 Physician United States
Primary
Concomitant
Septic Shock Life Threatening 2/5/2008 59 Male 262 lb 2/18/2008 Pharmacist United States
Primary
Concomitant
Pancytopenia Other Serious 2/5/2008 80 Male 136 lb 2/25/2008 Physician United States
Primary
Concomitant
Tremor Other Serious 1/28/2008 Male 278 lb 2/22/2008 United States
Primary
Concomitant
Left Ventricular Failure Hospitalization 12/25/2007 Male 180 lb 3/7/2008 Physician Australia
Primary
Concomitant
Pancytopenia Other Serious 2/26/2008 80 Male 136 lb 3/7/2008 Physician United States
Primary
Concomitant
Arthritis Hospitalization 2/10/2008 Male 165 lb 3/27/2008 Physician Netherlands
Primary
Concomitant
Retroperitoneal Abscess Death 9/1/2006 74 Male 3/27/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Arthritis Hospitalization 2/10/2008 Male 165 lb 4/7/2008 Physician Netherlands
Primary
Concomitant
Stevens-johnson Syndrome Other Serious 12/7/2006 64 Male 4/18/2008 Malaysia
Primary
Concomitant
Tricuspid Valve Incompetence Other Serious 2/27/2008 54 Female 150 lb 4/25/2008 Physician Italy
Primary
Concomitant
Unresponsive To Stimuli Hospitalization 1/7/2008 68 Female 210 lb 5/15/2008 Other Health Professional United States
Primary
Concomitant
Weight Increased 59 Male 6/6/2008 Physician United States
Primary
Concomitant
Sensory Loss Other Serious 5/23/2007 Male 251 lb 6/20/2008 Lawyer United States
Primary
Concomitant
Staphylococcal Sepsis Other Serious 1/1/2006 Male 195 lb 7/14/2008 Lawyer United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 2/27/2008 54 Female 150 lb 7/7/2008 Other Health Professional Italy
Primary
Concomitant
Staphylococcal Sepsis Other Serious 1/1/2006 Male 195 lb 7/21/2008 Lawyer United States
Primary
Secondary
Concomitant
Staphylococcal Sepsis Other Serious 1/1/2006 Male 195 lb 7/22/2008 Lawyer United States
Primary
Secondary
Concomitant
Vitamin D Decreased 4/29/2008 65 Male 7/7/2008 Consumer United States
Primary
Concomitant
Renal Haemorrhage Hospitalization 5/5/2008 85 Male 160 lb 8/19/2008 United States
Primary
Concomitant
Unresponsive To Stimuli Other Serious 1/1/2006 Male 195 lb 9/10/2008 Lawyer United States
Primary
Secondary
Concomitant
Burning Sensation 7/21/2008 56 Male 194 lb 9/16/2008 United States
Primary
Concomitant
Staphylococcal Sepsis Other Serious 1/1/2006 Male 195 lb 10/2/2008 Lawyer United States
Primary
Secondary
Concomitant
Viral Infection Hospitalization 1/1/2006 70 Male 195 lb 9/29/2008 Physician United States
Primary
Secondary
Concomitant
Lethargy Other Serious 4/18/2005 Male 10/17/2008 Physician United States
Primary
Concomitant
Lethargy Other Serious 4/18/2005 Male 10/24/2008 Consumer United States
Primary
Concomitant
Thrombotic Thrombocytopenic Purpura Hospitalization 7/9/2006 85 Male 11/11/2008 Australia
Primary
Secondary
Concomitant
Hypertensive Crisis Other Serious 11/26/2008 Male 12/8/2008 Physician Germany
Primary
Concomitant
Septic Shock Death 11/21/2008 Male 12/18/2008 Physician United States
Primary
Concomitant
Wound Haemorrhage Hospitalization 10/1/2008 82 Female 163 lb 12/19/2008 Consumer France
Primary
Secondary
Concomitant
Product Quality Issue Other Serious 2/28/2008 83 Female 12/19/2008 Consumer United States
Primary
Concomitant
Product Quality Issue Other Serious 1/1/2003 79 Female 180 lb 12/23/2008 Consumer United States
Primary
Secondary
Concomitant
Hypertensive Crisis Other Serious 11/26/2008 Male 1/9/2009 Physician Germany
Primary
Secondary
Concomitant
Emphysema 11/1/2008 Male 1/12/2009 Consumer
Primary
Concomitant
Thyroid Disorder Other Serious 1/1/2006 Male 1/23/2009 Consumer Canada
Primary
Concomitant
Skin Ulcer Hospitalization 5/1/2007 Female 1/26/2009 Physician Germany
Primary
Secondary
Concomitant
Urine Output Decreased Other Serious 9/1/2006 Male 195 lb 1/26/2009 Lawyer United States
Primary
Secondary
Concomitant
Thyroid Disorder Other Serious 1/1/2006 Male 2/5/2009 Physician Canada
Primary
Concomitant
Renal Disorder Other Serious Male 1/30/2009 Consumer United States
Primary
Secondary
Concomitant
Thyroid Disorder Other Serious 1/1/2006 Male 2/18/2009 Physician Canada
Primary
Concomitant
Weight Increased Male 2/24/2009 United States
Primary
Concomitant
Upper Limb Fracture Hospitalization 1/1/2007 Male 2/26/2009 Consumer Australia
Primary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 6/20/2007 66 Male 163 lb 2/23/2009 Physician United States
Primary
Concomitant
Upper Limb Fracture Hospitalization 1/1/2007 84 Male 181 lb 3/13/2009 Physician Australia
Primary
Concomitant
Unresponsive To Stimuli Other Serious 2/9/2009 88 Male 181 lb 3/17/2009 Physician United States
Primary
Secondary
Concomitant
Sensory Loss Other Serious 5/23/2007 Male 251 lb 3/20/2009 Physician United States
Primary
Concomitant
Upper Limb Fracture Hospitalization 1/1/2007 Male 181 lb 3/26/2009 Physician Australia
Primary
Concomitant
Urine Abnormality Hospitalization 3/2/2009 Female 212 lb 3/27/2009 Canada
Primary
Concomitant
Urine Abnormality Hospitalization 3/2/2009 Female 212 lb 4/30/2009 Canada
Primary
Concomitant
Lethargy Required Intervention 2/18/2009 79 Male 217 lb 2/18/2009 Pharmacist United States
Primary
Secondary
Concomitant
Malaise Hospitalization 5/2/2009 Male 150 lb 5/8/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Malaise Hospitalization 5/2/2009 Male 150 lb 5/14/2009 Physician United Kingdom
Primary
Concomitant
Hyperhidrosis 2/26/2008 Male 5/27/2009 United States
Primary
Concomitant
Tongue Disorder 12/1/2008 Female 180 lb 5/27/2009 United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 7/12/2005 Female 121 lb 6/19/2009 Physician Germany
Primary
Secondary
Concomitant
Central Nervous System Lymphoma Hospitalization 70 Female 7/2/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Central Nervous System Lymphoma Hospitalization 70 Female 7/2/2009 Consumer United States
Primary
Secondary
Concomitant
Wound Secretion Other Serious 7/1/2006 61 Male 7/7/2009 Lawyer United States
Primary
Secondary
Concomitant
Cerebrovascular Accident Hospitalization 70 Female 7/10/2009 United Kingdom
Primary
Secondary
Concomitant
Wound Secretion Other Serious 7/1/2006 61 Male 7/16/2009 Lawyer United States
Primary
Secondary
Concomitant
Postictal State Other Serious 4/13/2009 54 Male 215 lb 7/24/2009 Consumer United States
Primary
Concomitant
Tumour Lysis Syndrome Other Serious 6/27/2009 Male 143 lb 7/27/2009 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 6/6/2003 43 Male 213 lb 8/7/2009 United States
Primary
Concomitant
Tumour Lysis Syndrome Other Serious 6/27/2009 Male 145 lb 8/7/2009 United States
Primary
Concomitant
Renal Cell Carcinoma Life Threatening 5/5/2009 Male 214 lb 8/10/2009 Other Health Professional New Zealand
Primary
Concomitant
Weight Increased Life Threatening 57 Female 8/3/2009 United States
Primary
Concomitant
Septic Shock Death Male 8/11/2009 Physician Italy
Primary
Concomitant
Weight Increased Life Threatening 57 Female 8/11/2009 United States
Primary
Concomitant
Leiomyosarcoma Hospitalization 3/16/2005 72 Male 8/13/2009 Physician Germany
Primary
Secondary
Concomitant
Tumour Lysis Syndrome Other Serious 6/27/2009 Male 145 lb 8/20/2009 United States
Primary
Concomitant
Pruritus 12/1/2008 Male 8/22/2009 United States
Primary
Concomitant
Visual Impairment Other Serious 36 Male 8/18/2009 Lawyer United States
Primary
Concomitant
Vitamin D Deficiency Hospitalization 8/28/2008 61 Female 95 lb 8/25/2009 Pharmacist United States
Primary
Concomitant
Tumour Lysis Syndrome Other Serious 6/27/2009 Male 145 lb 9/2/2009 United States
Primary
Concomitant
Vomiting Death 1/1/2009 74 Male 9/8/2009 Other Health Professional Germany
Primary
Concomitant
Vomiting Other Serious 8/1/2009 79 Male 9/21/2009 Other Health Professional Germany
Primary
Concomitant
Visual Impairment Other Serious 9/1/1999 36 Male 9/15/2009 United States
Primary
Concomitant
Type 1 Diabetes Mellitus Other Serious 1/1/2001 43 Male 376 lb 9/23/2009 United States
Primary
Concomitant
Wound Secretion Other Serious 1/1/2006 60 Male 10/2/2009 Lawyer United States
Primary
Secondary
Concomitant
Transient Ischaemic Attack Other Serious 1/1/2004 Male 200 lb 10/9/2009 Pharmacist United States
Primary
Concomitant
Tubulointerstitial Nephritis Other Serious 2/12/2007 43 Female 10/8/2009 Other Health Professional United Kingdom
Primary
Concomitant
Visual Acuity Reduced Death 9/1/1999 36 Male 10/10/2009 United States
Primary
Concomitant
Neutropenia Death 1/2/2009 Female 10/15/2009 Pharmacist United States
Primary
Concomitant
Neutropenia Other Serious 12/18/2008 Female 10/20/2009 Pharmacist United States
Primary
Concomitant
Gastrointestinal Pain Hospitalization 9/1/2009 Female 10/21/2009 Other Health Professional United States
Primary
Concomitant
Visual Impairment Hospitalization 9/1/1999 36 Male 10/16/2009 United States
Primary
Concomitant
Tumour Lysis Syndrome Other Serious 6/27/2009 Male 145 lb 10/28/2009 United States
Primary
Concomitant
Visual Impairment Hospitalization 9/1/1999 36 Male 10/26/2009 United States
Primary
Concomitant
Chronic Myeloid Leukaemia Other Serious 10/29/2009 Male 139 lb 11/16/2009 Other Health Professional United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2000 35 Male 264 lb 11/17/2009 United States
Primary
Concomitant

Drug Data