Allopurinol combined with Digoxin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Melaena Hospitalization 10/1/2005 75 Male 1/2/2006
Primary
Secondary
Concomitant
Liver Disorder Hospitalization 12/14/2004 72 Female 1/6/2006 Physician Japan
Primary
Concomitant
Rectal Haemorrhage Hospitalization 75 Male 1/10/2006 Physician France
Primary
Secondary
Concomitant
Nausea Other Serious 40 Male 218 lb 1/12/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Hospitalization 1/1/2006 66 Male 211 lb 1/10/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Hospitalization 1/1/2006 66 Male 211 lb 1/9/2006 Physician United States
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Hospitalization 1/1/2006 66 Male 211 lb 1/10/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Death Other Serious 12/25/2004 74 Male 1/20/2006 Pharmacist United States
Primary
Concomitant
Vertigo Hospitalization 2/1/2005 83 Female 1/19/2006 Physician Czech Republic
Primary
Concomitant
Thrombocytopenia Other Serious 4/27/2005 Male 162 lb 1/31/2006 Other Health Professional United Kingdom
Primary
Concomitant
Melaena Hospitalization 11/8/2005 65 Male 1/27/2006 Pharmacist United States
Primary
Concomitant
Aortic Dissection Death 4/5/2005 Male 2/1/2006 Consumer United Kingdom
Primary
Secondary
Aortic Dissection Death 4/5/2005 Male 2/1/2006 Consumer United Kingdom
Primary
Secondary
Rash Hospitalization 10/20/2005 71 Male 11/5/2005 Pharmacist United States
Primary
Secondary
Concomitant
Hepatic Failure Death 81 Female 2/3/2006 Other Health Professional Australia
Primary
Secondary
Concomitant
Treatment Noncompliance Hospitalization 11/30/2005 Male 153 lb 1/3/2006 Other Health Professional United States
Primary
Concomitant
Haemorrhagic Infarction Death 1/26/2005 86 Male 160 lb 2/3/2006 Pharmacist United States
Primary
Concomitant
Restlessness Hospitalization 1/10/2006 78 Male 198 lb 2/8/2006
Primary
Concomitant
Renal Failure Hospitalization 11/1/2005 62 Male 2/3/2006 Sweden
Primary
Concomitant
Urine Output Decreased Hospitalization 81 Male 2/7/2006 Pharmacist United States
Primary
Secondary
Restlessness Hospitalization 1/10/2006 78 Male 2/10/2006 United Kingdom
Primary
Concomitant
Thrombocytopenia Life Threatening 12/10/2005 73 Female 2/18/2006 Pharmacist United States
Primary
Concomitant
Somnolence 5/22/2005 82 Male 172 lb 1/5/2006 United States
Primary
Concomitant
Renal Failure Acute Other Serious 1/5/2006 84 Male 2/16/2006 France
Primary
Secondary
Concomitant
Cholestasis Hospitalization 1/23/2006 91 Female 154 lb 2/27/2006 Consumer France
Primary
Secondary
Concomitant
Blood Glucose Increased 1/1/2006 Male 2/27/2006 Consumer United States
Primary
Concomitant
Gamma-glutamyltransferase Increased Hospitalization 1/23/2006 91 Female 154 lb 2/28/2006 Consumer France
Primary
Secondary
Concomitant
Oral Intake Reduced Other Serious 1/1/2006 78 Male 168 lb 2/22/2006 United States
Primary
Concomitant
Hepatitis Toxic Other Serious 10/18/2005 77 Male 3/2/2006 Physician Spain
Primary
Concomitant
Ventricular Hypertrophy Other Serious 7/3/2005 Female 195 lb 3/3/2006 Physician United States
Primary
Concomitant
Somnolence Hospitalization 1/5/2006 84 Male 2/26/2006 Other Health Professional France
Primary
Secondary
Concomitant
Scratch Hospitalization 9/15/2005 82 Female 2/22/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Sudden Death Death 11/8/2004 78 Male 112 lb 3/9/2006 Consumer United Kingdom
Primary
Concomitant
Vascular Bypass Graft Other Serious 2/10/2006 67 Male 3/8/2006 Other Health Professional United States
Primary
Concomitant
Skin Inflammation Hospitalization 9/15/2005 82 Female 2/22/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Wound Infection Other Serious 1/1/1999 83 Male 256 lb 3/16/2006 Physician United States
Primary
Concomitant
Tricuspid Valve Incompetence Hospitalization 63 Male 3/16/2006
Primary
Secondary
Concomitant
Poor Peripheral Circulation Other Serious 1/1/2005 76 Female 170 lb 3/10/2006 United States
Primary
Concomitant
Tricuspid Valve Incompetence Hospitalization 63 Male 3/21/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Tricuspid Valve Incompetence Hospitalization 63 Male 3/15/2006 Pharmacist United States
Primary
Secondary
Concomitant
Obstruction Hospitalization 74 Male 3/16/2006 Pharmacist United States
Primary
Secondary
Concomitant
Ventricular Tachycardia Life Threatening 5/23/2003 68 Male 194 lb 3/17/2006 United States
Primary
Concomitant
Sclerosing Encapsulating Peritonitis Other Serious 4/2/2005 56 Male 125 lb 3/21/2006 Physician Japan
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 3/19/2006 70 Male 166 lb 3/24/2006 Pharmacist United States
Primary
Concomitant
Aortic Dissection Death Male 3/29/2006
Primary
Secondary
Urine Colour Abnormal Hospitalization 1/28/2005 45 Male 3/27/2006 Physician Philippines
Primary
Concomitant
Tricuspid Valve Incompetence Hospitalization 63 Male 3/28/2006 United States
Primary
Secondary
Concomitant
Tricuspid Valve Incompetence Hospitalization 63 Male 3/28/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Wound Infection Other Serious 1/1/1999 83 Male 256 lb 4/14/2006 Physician United States
Primary
Concomitant
Vomiting 1/1/2005 46 Female 154 lb 1/25/2006 Other Health Professional United States
Primary
Concomitant
Pulmonary Mycosis Other Serious 3/10/2006 64 Male 4/11/2006 Physician Sweden
Primary
Concomitant
Pulmonary Toxicity Required Intervention 4/26/2005 72 Male 175 lb 4/20/2006 Pharmacist United States
Primary
Concomitant
Vitamin B12 Increased Other Serious 2/8/2006 Female 172 lb 4/24/2006 Physician Australia
Primary
Secondary
Concomitant
Sepsis Hospitalization 1/1/2002 68 Male 201 lb 4/24/2006 Physician United States
Primary
Concomitant
Wound Infection Other Serious 1/1/1999 83 Male 256 lb 4/27/2006 Physician United States
Primary
Concomitant
Therapy Non-responder Hospitalization 11/16/2005 29 Male 4/19/2006 Physician Australia
Primary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 1/22/2006 83 Female 4/26/2006 Sweden
Primary
Secondary
Concomitant
Jaundice Cholestatic Hospitalization 3/28/2006 67 Female 173 lb 5/11/2006 Pharmacist United States
Primary
Concomitant
Polyuria Hospitalization 2/18/2006 67 Male 265 lb 5/15/2006 Consumer France
Primary
Secondary
Concomitant
Staphylococcal Infection Other Serious 4/10/2006 79 Male 140 lb 5/9/2006 Physician United States
Primary
Secondary
Concomitant
Weight Increased Hospitalization 10/27/2004 47 Male 243 lb 5/10/2006 Other Health Professional United States
Primary
Concomitant
Therapeutic Response Decreased Other Serious 1/1/2006 Female 172 lb 5/18/2006 Physician Australia
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 9/29/2003 Male 5/16/2006 United States
Primary
Secondary
Concomitant
Vascular Purpura Hospitalization 3/10/2006 67 Male 194 lb 5/22/2006 Physician France
Primary
Concomitant
Eosinophilia Other Serious 3/9/2006 93 Female 5/24/2006 France
Primary
Secondary
Concomitant
Blood Parathyroid Hormone Increased 8/22/2005 Male 3/13/2006 United States
Primary
Secondary
Concomitant
Blood Parathyroid Hormone Increased 8/22/2005 Male 3/13/2006 United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Life Threatening 3/29/2006 72 Male 229 lb 5/31/2006 Pharmacist United States
Primary
Secondary
Concomitant
Urticaria Generalised Hospitalization 2/20/2005 54 Female 130 lb 5/25/2006 Other Health Professional United Kingdom
Primary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 5/14/2006 82 Female 137 lb 6/1/2006 Other Health Professional United States
Primary
Concomitant
Muscular Weakness Other Serious 12/1/2005 60 Female 320 lb 4/20/2006 Consumer United States
Primary
Concomitant
Chest Pain Hospitalization 10/31/2004 89 Female 6/8/2006 Other Health Professional Sweden
Primary
Secondary
Concomitant
Hypoaesthesia Facial 50 Female 247 lb 4/25/2006 Pharmacist United States
Primary
Concomitant
Prothrombin Time Prolonged Hospitalization 5/14/2006 82 Female 137 lb 6/7/2006 Other Health Professional United States
Primary
Concomitant
Therapeutic Response Decreased Other Serious 1/1/2006 Female 172 lb 6/21/2006 Physician Australia
Primary
Secondary
Concomitant
Prothrombin Level Decreased Other Serious 1/10/2000 75 Male 6/14/2006 Canada
Primary
Secondary
Concomitant
Skin Nodule Hospitalization 10/1/2003 Female 119 lb 6/22/2006 Germany
Primary
Concomitant
Prothrombin Level Decreased Other Serious 1/25/2000 74 Male 6/21/2006 Canada
Primary
Secondary
Concomitant
Pancreatitis Other Serious 11/9/2005 67 Male 191 lb 5/23/2006 Physician United States
Primary
Concomitant
Sinusitis Hospitalization 2/14/2006 73 Female 143 lb 6/23/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Pulmonary Mycosis Other Serious 3/10/2006 64 Male 6/28/2006 Physician Sweden
Primary
Concomitant
Disease Progression Life Threatening 4/8/2003 62 Female 82 lb 7/12/2006 Japan
Primary
Secondary
Concomitant
Pulmonary Hypertension Hospitalization 7/14/2005 41 Female 143 lb 7/13/2006 Physician Japan
Primary
Concomitant
Ventricular Tachycardia Hospitalization 52 Female 132 lb 7/13/2006 Pharmacist United States
Primary
Secondary
Concomitant
Pericarditis Constrictive Hospitalization 10/1/2003 Female 119 lb 7/20/2006 Germany
Primary
Concomitant
Granulocytopenia Required Intervention 1/31/2006 59 Male 4/3/2006 United States
Primary
Concomitant
Thrombocytopenia Other Serious 4/13/2006 80 Male 220 lb 7/21/2006 Physician France
Primary
Concomitant
Vomiting Hospitalization 74 Male 7/21/2006 Other Health Professional Denmark
Primary
Concomitant
International Normalised Ratio Increased Hospitalization 6/14/2005 80 Male 8/1/2006 Pharmacist United States
Primary
Concomitant
Aplasia Pure Red Cell Life Threatening 12/19/2003 62 Female 82 lb 8/3/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
White Blood Cell Count Increased Death 2/16/2006 70 Female 7/27/2006 Physician Japan
Primary
Secondary
Concomitant
Vomiting Hospitalization 74 Male 7/31/2006 Other Health Professional Denmark
Primary
Secondary
Concomitant
Pleural Effusion Hospitalization 78 Male 6/17/2006 Physician United States
Primary
Concomitant
Medication Residue Other Serious 1/1/2002 72 Female 128 lb 8/4/2006 United States
Primary
Concomitant
Therapeutic Response Decreased 11/7/2005 74 Female 8/9/2006 Physician United States
Primary
Concomitant
Aplasia Pure Red Cell Life Threatening 12/19/2003 62 Female 82 lb 8/3/2006 Japan
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 74 Male 8/17/2006 Consumer France
Primary
Concomitant
Pharmaceutical Product Complaint 1/1/2002 72 Female 128 lb 8/14/2006 United States
Primary
Concomitant
Therapeutic Agent Toxicity Other Serious 7/10/2006 72 Female 8/23/2006 Consumer United Kingdom
Primary
Secondary
Concomitant
Supraventricular Tachycardia Other Serious 7/10/2006 72 Female 8/21/2006 United Kingdom
Primary
Secondary
Concomitant
Cerebrovascular Accident Hospitalization 2/26/2006 71 Male 8/18/2006 Physician United States
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Life Threatening 7/10/2006 72 Female 8/28/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Lactic Acidosis Hospitalization 77 Male 8/22/2006 United Kingdom
Primary
Concomitant
Treatment Noncompliance Required Intervention 5/3/2006 67 Female 8/16/2006 Physician United States
Primary
Concomitant
Lactic Acidosis Hospitalization 77 Male 8/23/2006 United Kingdom
Primary
Concomitant
Retroperitoneal Haematoma Death 5/6/2006 65 Female 397 lb 8/29/2006 Pharmacist United States
Primary
Concomitant
Supraventricular Tachycardia Other Serious 7/10/2006 72 Female 8/31/2006 United Kingdom
Primary
Secondary
Concomitant
Paraesthesia 4/10/2006 55 Female 170 lb 7/24/2006 Pharmacist United States
Primary
Concomitant
Ventricular Tachycardia Life Threatening 5/23/2003 68 Male 194 lb 9/5/2006 United States
Primary
Concomitant
Aspartate Aminotransferase Increased Other Serious 4/13/2006 14 Female 97 lb 9/6/2006 Physician Japan
Primary
Concomitant
Ventricular Tachycardia Life Threatening 5/23/2003 68 Male 194 lb 9/8/2006 United States
Primary
Concomitant
Rectal Haemorrhage Other Serious 1/18/2006 78 Male 9/13/2006 Other Health Professional United States
Primary
Concomitant
Infusion Site Pain Other Serious 1/1/2005 64 Male 142 lb 9/15/2006 United States
Primary
Secondary
Concomitant
International Normalised Ratio Abnormal Life Threatening 6/4/2006 89 Male 155 lb 6/5/2006 Pharmacist United States
Primary
Concomitant
International Normalised Ratio Increased Hospitalization 4/25/2006 Male 203 lb 4/26/2006 Pharmacist United States
Primary
Concomitant
Renal Impairment Hospitalization 5/9/2006 83 Male 9/20/2006 Japan
Primary
Secondary
Concomitant
Vascular Calcification Life Threatening 10/15/2005 67 Male 183 lb 9/28/2006 United States
Primary
Concomitant
Sudden Death Death 4/5/2005 Male 9/28/2006 Physician United Kingdom
Primary
Secondary
International Normalised Ratio Increased Hospitalization 9/27/2006 62 Male 230 lb 9/29/2006 Pharmacist United States
Primary
Concomitant
Hypophosphataemia Hospitalization 7/5/2006 69 Male 10/5/2006 United Kingdom
Primary
Concomitant
Social Avoidant Behaviour 1/1/2006 96 Male 7/31/2006 Consumer United States
Primary
Secondary
Concomitant
Ventricular Fibrillation Hospitalization 9/1/2004 75 Male 10/10/2006 Physician Japan
Primary
Concomitant
Respiratory Tract Infection Hospitalization 9/22/2005 65 183 lb 10/11/2006 Physician Ireland
Primary
Concomitant
Staphylococcal Infection Hospitalization 9/16/2005 65 183 lb 10/19/2006 Physician Ireland
Primary
Concomitant
Nodal Arrhythmia Death 7/26/2006 86 Female 8/25/2006 Pharmacist United States
Primary
Concomitant
Pneumonia Hospitalization 66 Male 10/20/2006 Consumer United States
Primary
Concomitant
Erysipelas Hospitalization 5/1/2006 64 Female 10/24/2006 Consumer Sweden
Primary
Concomitant
Ventricular Tachycardia Life Threatening 5/23/2003 68 Male 194 lb 10/19/2006 United States
Primary
Concomitant
Hypoparathyroidism Other Serious 80 Male 10/27/2006 Other Health Professional Australia
Primary
Concomitant
Renal Failure Acute Hospitalization 9/23/2006 59 Male 10/26/2006 United States
Primary
Secondary
Concomitant
Hypoparathyroidism Other Serious 80 Male 11/3/2006 Other Health Professional Australia
Primary
Concomitant
Myelofibrosis Other Serious 1/1/2006 73 Male 237 lb 10/27/2006 Other Health Professional United States
Primary
Concomitant
Surgery Hospitalization 7/12/2005 70 Male 11/7/2006 Physician Japan
Primary
Concomitant
Abnormal Dreams 1/1/2003 62 Male 11/13/2006 Consumer United States
Primary
Concomitant
Death Death 10/1/2006 88 Female 11/7/2006 Physician United States
Primary
Concomitant
Muscular Weakness Other Serious 11/18/2006 79 Female 11/21/2006 Consumer United States
Primary
Concomitant
Myocardial Infarction Death 5/2/2006 71 Female 250 lb 11/17/2006 United States
Primary
Concomitant
Weight Decreased Hospitalization 70 Male 12/1/2006 Consumer United States
Primary
Concomitant
Myalgia Other Serious 11/22/2006 Physician Ireland
Primary
Concomitant
Vomiting Hospitalization Male 12/6/2006 Consumer Japan
Primary
Secondary
Concomitant
Sclerosing Encapsulating Peritonitis Other Serious 4/2/2005 56 Male 125 lb 11/21/2006 Physician Japan
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 8/4/2006 87 Female 11/28/2006 Pharmacist Spain
Primary
Secondary
Pulmonary Hypertension Hospitalization 7/14/2005 41 Female 143 lb 11/30/2006 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 10/23/2006 84 Male 11/30/2006 Japan
Primary
Concomitant
Speech Disorder Other Serious 72 Male 250 lb 11/30/2006 United States
Primary
Concomitant
Hepatitis Cholestatic Hospitalization 11/15/2006 80 Male 12/12/2006 Physician France
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 8/4/2006 87 Female 12/4/2006 Other Health Professional Spain
Primary
Secondary
Retinal Artery Occlusion Disability 10/23/2006 75 Male 174 lb 12/14/2006 Other Health Professional United Kingdom
Primary
Concomitant
Hypotension Hospitalization 9/1/2006 Male 172 lb 12/14/2006 Other Health Professional United States
Primary
Concomitant
Neutropenia Required Intervention 9/6/2006 75 Male 144 lb 10/2/2006 Consumer United States
Primary
Concomitant

Drug Data