Allopurinol combined with Darbepoetin Alfa

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Eosinophilia 10/2/2005 68 293 lb 1/6/2006 Pharmacist United States
Primary
Concomitant
Myocardial Infarction Hospitalization 11/15/2005 Male 1/31/2006 Physician Canada
Primary
Concomitant
Renal Failure Acute Hospitalization 2/1/2006 46 Male 170 lb 3/31/2006 Consumer United States
Primary
Concomitant
Renal Failure Acute Other Serious 2/1/2006 46 Male 170 lb 4/27/2006 Consumer United States
Primary
Concomitant
Renal Impairment Other Serious 77 Male 6/30/2006 Pharmacist Canada
Primary
Secondary
Concomitant
Prothrombin Time Prolonged Hospitalization 7/1/2006 61 Male 139 lb 9/8/2006 Other Health Professional Switzerland
Primary
Concomitant
Interacting
Pneumonitis Hospitalization 7/30/2006 89 Female 163 lb 9/29/2006 Consumer United States
Primary
Concomitant
Myocardial Infarction Hospitalization 8/27/2006 65 Male 161 lb 10/2/2006 Physician Austria
Primary
Concomitant
Multi-organ Failure Other Serious 8/27/2006 65 Male 161 lb 10/27/2006 Physician Austria
Primary
Concomitant
Nephrogenic Fibrosing Dermopathy Other Serious 1/3/2007 69 Female 172 lb 3/13/2007 Physician United States
Primary
Concomitant
International Normalised Ratio Increased Hospitalization 3/20/2007 52 Male 4/9/2007 Denmark
Primary
Concomitant
Nephrogenic Fibrosing Dermopathy Other Serious 1/3/2007 69 Female 172 lb 4/25/2007 Consumer United States
Primary
Concomitant
Respiratory Arrest Life Threatening 3/27/2007 62 Male 260 lb 5/9/2007 Consumer United States
Primary
Concomitant
Vomiting Other Serious 7/11/2006 77 Male 176 lb 5/16/2007 Other Health Professional Portugal
Primary
Concomitant
Vomiting Life Threatening 4/21/2006 75 Male 5/23/2007 Other Health Professional Australia
Primary
Secondary
Concomitant
Cardiac Failure Death 3/19/2007 52 Female 6/23/2007 Other Health Professional Czech Republic
Primary
Secondary
Concomitant
Cardiac Failure Death 3/19/2007 52 Female 6/21/2007 Czech Republic
Primary
Secondary
Concomitant
Vomiting Other Serious 7/11/2006 77 Male 176 lb 7/24/2007 Other Health Professional Portugal
Primary
Concomitant
Nephrogenic Systemic Fibrosis Other Serious 1/3/2007 69 Female 172 lb 8/7/2007 Consumer United States
Primary
Concomitant
Urinary Tract Infection Other Serious 21 Female 9/5/2007 Other Health Professional United States
Primary
Secondary
Renal Impairment Other Serious 1/1/2006 54 Female 9/19/2007 Other Health Professional Italy
Primary
Concomitant
Interacting
Rhabdomyolysis Other Serious 12/1/2006 48 Female 10/30/2007 Other Health Professional France
Primary
Secondary
Concomitant
Weight Decreased Other Serious 7/1/2007 Female 11/2/2007 Other Health Professional France
Primary
Concomitant
Interacting
Weight Decreased Other Serious 7/1/2007 Female 11/14/2007 Other Health Professional France
Primary
Concomitant
Interacting
Sinus Tachycardia Hospitalization 10/17/2007 Male 130 lb 11/15/2007 Greece
Primary
Concomitant
Infection Hospitalization 12/11/2007 79 Male 168 lb 12/31/2007 Physician Finland
Primary
Secondary
Concomitant
Acute Pulmonary Oedema Hospitalization 10/17/2007 Male 130 lb 1/11/2008 Greece
Primary
Concomitant
Acute Pulmonary Oedema Hospitalization 10/17/2007 Male 130 lb 2/11/2008 Greece
Primary
Concomitant
Infection Hospitalization 12/11/2007 79 Male 168 lb 3/7/2008 Physician Finland
Primary
Secondary
Concomitant
Pleural Effusion Hospitalization 3/10/2006 59 Male 3/10/2008 Consumer Sweden
Primary
Concomitant
Sinusitis Hospitalization 6/6/2006 Male 3/10/2008 Physician United States
Primary
Secondary
Concomitant
Pleural Effusion Hospitalization 3/10/2006 59 Male 3/12/2008 Consumer Sweden
Primary
Concomitant
Pancytopenia Hospitalization 12/21/2007 Female 3/21/2008 Physician Australia
Primary
Secondary
Concomitant
Sinusitis Hospitalization 5/22/2006 Male 3/26/2008 Consumer France
Primary
Secondary
Concomitant
Cardio-respiratory Arrest Hospitalization 10/17/2007 Male 130 lb 4/9/2008 Greece
Primary
Concomitant
Sinusitis Hospitalization 5/22/2006 Male 4/15/2008 Consumer France
Primary
Secondary
Concomitant
Hypocalcaemia Life Threatening 1/25/2007 42 Female 125 lb 5/1/2008 Physician United States
Primary
Concomitant
Pancytopenia Hospitalization 12/21/2007 Female 5/2/2008 Physician Australia
Primary
Secondary
Concomitant
Hypocalcaemia Life Threatening 1/25/2007 47 Female 125 lb 6/23/2008 United States
Primary
Concomitant
Renal Failure Other Serious 3/1/2008 65 Male 6/30/2008 Other Health Professional Norway
Primary
Secondary
Concomitant
Renal Failure Other Serious 3/1/2008 65 Male 7/1/2008 Other Health Professional Norway
Primary
Secondary
Concomitant
Pancytopenia Hospitalization 12/21/2007 Female 7/23/2008 Physician Australia
Primary
Secondary
Concomitant
Paraesthesia Hospitalization 43 Female 7/30/2008 Other Health Professional United States
Primary
Concomitant
Paraesthesia Hospitalization 43 Female 10/16/2008 Other Health Professional United States
Primary
Concomitant
Pleurisy Hospitalization 11/9/2008 Male 203 lb 12/3/2008 Germany
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 2/27/2008 75 Male 12/19/2008 Other Health Professional Australia
Primary
Concomitant
Renal Failure Acute Hospitalization 10/1/2007 Male 12/23/2008 Other Health Professional Norway
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 10/1/2007 Male 12/29/2008 Other Health Professional Norway
Primary
Secondary
Concomitant
Optic Neuritis Other Serious 12/19/2008 37 Male 1/7/2009 Other Health Professional Spain
Primary
Concomitant
Rhabdomyolysis Hospitalization 10/1/2007 Male 1/21/2009 Other Health Professional Norway
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 5/17/2005 29 Female 5/7/2009 Other Health Professional Spain
Primary
Secondary
Concomitant
Activated Partial Thromboplastin Time Prolonged 5/11/2009 61 Female 5/20/2009 Pharmacist United States
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 11/28/2008 Male 200 lb 6/2/2009 Physician Poland
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 2/28/2009 Male 185 lb 6/2/2009 Physician Poland
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 11/28/2008 Male 200 lb 6/12/2009 Physician Poland
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 2/28/2009 Male 185 lb 6/12/2009 Physician Poland
Primary
Secondary
Concomitant
Activated Partial Thromboplastin Time Prolonged 5/11/2009 61 Female 6/16/2009 Pharmacist United States
Primary
Secondary
Concomitant
Wound Secretion Other Serious 7/1/2006 61 Male 7/7/2009 Lawyer United States
Primary
Secondary
Concomitant
Wound Secretion Other Serious 7/1/2006 61 Male 7/16/2009 Lawyer United States
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 11/28/2008 Male 200 lb 8/12/2009 Physician Poland
Primary
Secondary
Concomitant
Wound Secretion Other Serious 1/1/2006 60 Male 10/2/2009 Lawyer United States
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 9/22/2009 77 Male 154 lb 12/21/2009 Physician United States
Primary
Concomitant
Respiratory Failure Hospitalization 9/22/2009 77 Male 154 lb 12/31/2009 Physician United States
Primary
Concomitant
Respiratory Failure Hospitalization 9/22/2009 77 Male 154 lb 1/5/2010 Physician United States
Primary
Concomitant
White Blood Cell Count Increased Other Serious 1/1/2009 Female 205 lb 2/23/2010 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 1/1/2009 Female 205 lb 3/4/2010 Physician United States
Primary
Secondary
Concomitant
Cardiac Arrest Death 11/9/2007 Female 3/11/2010 Physician United States
Primary
Concomitant
Wound Infection Staphylococcal Other Serious 4/1/1997 Female 138 lb 3/12/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Life Threatening 8/24/2007 Female 3/12/2010 Physician United States
Primary
Concomitant
Wound Infection Staphylococcal Other Serious 4/1/1997 Female 138 lb 3/24/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Other Serious 4/1/1997 Female 138 lb 3/29/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Pneumonitis Other Serious 57 Male 3/31/2010 Physician Italy
Primary
Secondary
Concomitant
Pneumonia Other Serious 1/1/2009 56 Male 4/6/2010 Other Health Professional Italy
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Other Serious 4/1/1997 55 Female 138 lb 4/14/2010 United States
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Other Serious 4/1/1997 55 Female 138 lb 5/5/2010 United States
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Other Serious 4/1/1997 55 Female 138 lb 5/19/2010 United States
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Other Serious 4/1/1997 55 Female 138 lb 5/21/2010 United States
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Other Serious 4/1/1997 55 Female 138 lb 6/9/2010 United States
Primary
Secondary
Concomitant
Wound Secretion Other Serious 1/1/2006 60 Male 6/11/2010 Lawyer United States
Primary
Secondary
Concomitant
Hallucinations, Mixed Hospitalization 5/1/2010 58 Female 260 lb 6/15/2010 Physician Canada
Primary
Concomitant
Wound Secretion Other Serious 1/1/2006 60 Male 300 lb 6/17/2010 Lawyer United States
Primary
Secondary
Concomitant
Infection Hospitalization 6/23/2010 7/2/2010 Physician Greece
Primary
Concomitant
Wound Infection Staphylococcal Other Serious 4/1/1997 55 Female 138 lb 7/7/2010 United States
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Other Serious 4/1/1997 55 Female 138 lb 7/23/2010 United States
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Other Serious 4/1/1997 55 Female 138 lb 8/20/2010 United States
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Other Serious 4/1/1997 55 Female 138 lb 8/24/2010 United States
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Other Serious 4/1/1997 55 Female 138 lb 8/27/2010 United States
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Other Serious 4/1/1997 55 Female 138 lb 9/6/2010 United States
Primary
Secondary
Concomitant
Pyrexia Other Serious 7/27/2009 73 Male 190 lb 9/16/2010 Other Health Professional United States
Primary
Concomitant
Wound Infection Staphylococcal Other Serious 4/1/1997 55 Female 138 lb 9/29/2010 United States
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Other Serious 4/1/1997 55 Female 138 lb 10/27/2010 United States
Primary
Secondary
Concomitant
Cardiotoxicity Death 2/1/2010 57 Male 11/2/2010 Physician Spain
Primary
Secondary
Concomitant
Cardiotoxicity Death 2/1/2010 57 Male 11/3/2010 Physician Spain
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Other Serious 4/1/1997 55 Female 138 lb 11/12/2010 United States
Primary
Secondary
Concomitant
Inappropriate Antidiuretic Hormone Secretion Hospitalization 10/31/2008 52 Male 12/3/2010 Physician United States
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Other Serious 4/1/1997 55 Female 138 lb 12/7/2010 United States
Primary
Secondary
Concomitant
Cardiotoxicity Death 2/1/2010 57 Male 12/23/2010 Physician Spain
Primary
Secondary
Concomitant
Cardiac Arrest Death 7/16/2010 57 Male 12/27/2010 Physician Spain
Primary
Secondary
Concomitant
Asthenia Death 2/1/2010 57 Male 1/4/2011 Physician Spain
Primary
Secondary
Concomitant
Stress Fracture Hospitalization 4/27/2000 58 Female 138 lb 1/12/2011 United States
Primary
Secondary
Concomitant
Hypogammaglobulinaemia Hospitalization 4/27/2000 58 Female 138 lb 1/18/2011 United States
Primary
Secondary
Concomitant
Haemoglobinopathy Other Serious 11/9/2010 Female 121 lb 1/24/2011 Physician Belgium
Primary
Secondary
Concomitant
Drug Interaction Other Serious 7/1/2007 79 Male 2/8/2011 Physician France
Primary
Concomitant
Interacting
Stress Fracture Other Serious 4/27/2000 58 Female 138 lb 4/6/2011 Physician United States
Primary
Secondary
Concomitant
Gastric Cancer Hospitalization 6/7/2010 86 Female 4/8/2011 Physician Portugal
Primary
Concomitant
Gastric Cancer Hospitalization 6/7/2010 86 Female 5/12/2011 Physician Portugal
Primary
Concomitant
Sudden Death Death 3/23/2011 75 Male 148 lb 5/13/2011 Physician Germany
Primary
Concomitant
Lower Gastrointestinal Haemorrhage Hospitalization 7/5/2010 73 Male 5/27/2011 Physician Spain
Primary
Concomitant
Interacting
Drug Interaction Hospitalization 7/5/2010 73 Male 6/1/2011 Physician Spain
Primary
Concomitant
Interacting
Nervous System Disorder Hospitalization 6/8/2011 72 Male 6/23/2011 Physician Sweden
Primary
Secondary
Concomitant
Gastrooesophageal Reflux Disease Other Serious 4/27/2000 58 Female 138 lb 6/29/2011 Physician United States
Primary
Secondary
Concomitant
Colon Cancer Other Serious 9/29/2010 80 Male 7/12/2011 Physician Spain
Primary
Concomitant
Mobility Decreased Other Serious 12/1/2006 79 Male 187 lb 7/14/2011 Lawyer United States
Primary
Concomitant
Stress Fracture Hospitalization 4/27/2000 58 Female 138 lb 7/15/2011 United States
Primary
Secondary
Concomitant
Pain Hospitalization 3/23/2011 75 Male 148 lb 7/15/2011 Physician Germany
Primary
Concomitant
Hypertension Hospitalization 8/29/2010 74 Female 7/27/2011 Physician Poland
Primary
Secondary
Concomitant
Pain Other Serious 1/1/2005 75 Male 182 lb 8/11/2011 Consumer United States
Primary
Secondary
Concomitant
Enteritis Other Serious 4/27/2000 58 Female 138 lb 8/19/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Enterocolitis Haemorrhagic Other Serious 8/16/2011 62 Female 9/13/2011 Physician Italy
Primary
Concomitant
Aortic Aneurysm Rupture Death 9/15/2003 87 Male 9/20/2011 Physician Spain
Primary
Concomitant
Myocardial Infarction Hospitalization 6/21/2010 63 Female 104 lb 9/22/2011 Physician Italy
Primary
Secondary
Concomitant
Aplasia Pure Red Cell Hospitalization 53 9/26/2011 Other Health Professional Belgium
Primary
Concomitant
Aplasia Pure Red Cell Hospitalization 53 9/26/2011 Other Health Professional Belgium
Primary
Concomitant
Arthralgia Other Serious 4/1/2005 50 Male 170 lb 9/27/2011 Consumer United States
Primary
Secondary
Concomitant
Cardiac Amyloidosis Other Serious 6/17/2008 70 Female 153 lb 9/27/2011 Other Health Professional Italy
Primary
Secondary
Concomitant
Cerebral Ischaemia Other Serious 6/21/2010 63 Female 104 lb 10/21/2011 Italy
Primary
Secondary
Concomitant
Aplasia Pure Red Cell Other Serious 46 Male 11/21/2011 Physician Czech Republic
Primary
Concomitant
Angina Pectoris Hospitalization 6/21/2010 63 Female 101 lb 12/13/2011 Italy
Primary
Secondary
Concomitant
Cerebrovascular Accident Other Serious 6/21/2010 63 Female 101 lb 12/27/2011 Italy
Primary
Secondary
Concomitant
Lethargy Hospitalization 6/21/2010 63 Female 104 lb 1/2/2012 Italy
Primary
Secondary
Concomitant
Cerebral Ischaemia Disability 6/21/2010 63 Female 101 lb 1/3/2012 Italy
Primary
Secondary
Concomitant
Spinal Compression Fracture Other Serious 6/21/2010 63 Female 101 lb 1/4/2012 Italy
Primary
Secondary
Concomitant
Cerebral Ischaemia Hospitalization 6/21/2010 63 Female 101 lb 1/18/2012 Italy
Primary
Secondary
Concomitant
Chronic Myeloid Leukaemia Other Serious 6/21/2010 63 Female 101 lb 1/19/2012 Italy
Primary
Secondary
Concomitant
Angina Pectoris Disability 6/21/2010 63 Female 101 lb 2/9/2012 Italy
Primary
Secondary
Concomitant
Spinal Compression Fracture Hospitalization 6/21/2010 63 Female 101 lb 2/13/2012 Physician Italy
Primary
Secondary
Concomitant
Drug Effect Decreased Death 12/16/2009 42 Male 154 lb 2/17/2012 Physician Japan
Primary
Secondary
Concomitant
Catheter Removal Other Serious 12/16/2009 42 Male 154 lb 2/21/2012 Physician Japan
Primary
Secondary
Concomitant
Oral Pain 3/9/2012 74 Male 3/28/2012 Consumer United States
Primary
Concomitant
Pulmonary Embolism Disability 5/10/2011 73 Male 176 lb 3/30/2012 Physician United States
Primary
Concomitant
Puncture Site Haemorrhage Life Threatening 3/18/2012 78 Male 4/4/2012 Other Health Professional Portugal
Primary
Concomitant
Hospitalisation Hospitalization 4/21/2012 71 Male 5/1/2012 Physician United States
Primary
Concomitant
Neutropenia Life Threatening 3/18/2012 79 Male 5/2/2012 Other Health Professional Portugal
Primary
Concomitant
Hypertension Hospitalization 35 Female 5/11/2012 Physician Spain
Primary
Concomitant
Premature Baby Other Serious 5 lb 5/11/2012 Physician Spain
Primary
Concomitant
Focal Segmental Glomerulosclerosis 7/7/2010 52 Male 10/27/2010 Physician United States
Primary
Secondary
Concomitant
Device Related Infection Hospitalization 3/18/2012 78 Male 5/14/2012 Portugal
Primary
Concomitant
Puncture Site Haemorrhage Life Threatening 3/18/2012 78 Male 5/21/2012 Other Health Professional Portugal
Primary
Secondary
Concomitant
Forced Expiratory Volume Decreased Other Serious 33 Female 5/29/2012 Other Health Professional Ireland
Primary
Secondary
Acute Myocardial Infarction Hospitalization 4/26/2012 68 Male 240 lb 6/5/2012 Physician Canada
Primary
Secondary
Concomitant

Drug Data