Allopurinol combined with Cytarabine

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Renal Failure Other Serious 11/16/2005 Female 106 lb 12/27/2005 United States
Primary
Secondary
White Blood Cell Count Decreased Hospitalization 11/9/2005 64 Male 171 lb 1/5/2006 United States
Primary
Secondary
Concomitant
Bradycardia Required Intervention 12/22/2005 Male 240 lb 1/4/2006 Pharmacist United States
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 9/18/2001 53 Male 95 lb 1/9/2006 Physician Japan
Primary
Secondary
Concomitant
Venoocclusive Disease Life Threatening 11/23/2005 63 Female 121 lb 1/12/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 1/14/2006 54 Male 214 lb 1/25/2006 Physician Netherlands
Primary
Secondary
Concomitant
Skin Toxicity Other Serious 1/13/2006 32 Female 183 lb 1/25/2006 Physician Netherlands
Primary
Secondary
Concomitant
Pyrexia Life Threatening 1/17/2005 Male 207 lb 2/8/2006 Other Health Professional United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 1/13/2006 32 Female 183 lb 2/1/2006 Physician Netherlands
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 1/14/2006 54 Male 214 lb 2/1/2006 Physician Netherlands
Primary
Secondary
Concomitant
Renal Failure Hospitalization 8/25/2005 61 Male 2/8/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Life Threatening 7/5/2001 34 Male 2/8/2006 United Kingdom
Primary
Concomitant
Herpes Simplex Serology Positive Other Serious 6/10/2005 26 Female 182 lb 2/10/2006 United States
Primary
Secondary
Concomitant
Therapy Non-responder Other Serious 1/13/2006 32 Female 183 lb 2/9/2006 Physician Netherlands
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 1/14/2006 54 Male 214 lb 2/10/2006 Physician Netherlands
Primary
Secondary
Concomitant
Herpes Simplex Other Serious 6/10/2005 26 Female 182 lb 2/14/2006 United States
Primary
Secondary
Concomitant
Platelet Count Decreased Hospitalization 10/30/2004 29 Female 121 lb 2/18/2006 Other Health Professional United States
Primary
Concomitant
Thrombosis Death 10/31/2005 77 Male 2/23/2006 Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 1/14/2006 54 Male 214 lb 2/23/2006 Physician Netherlands
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 1/13/2006 32 Female 190 lb 2/23/2006 Physician Netherlands
Primary
Secondary
Concomitant
Stomatitis Hospitalization 1/25/2006 81 Male 160 lb 3/4/2006 Other Health Professional United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 1/13/2006 32 Female 183 lb 3/1/2006 Physician Netherlands
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 11/10/2004 68 Male 152 lb 3/7/2006 Physician Japan
Primary
Secondary
Concomitant
Pancytopenia Hospitalization 1/23/2006 81 Male 160 lb 3/10/2006 United States
Primary
Secondary
Concomitant
Staphylococcal Bacteraemia Other Serious 1/30/2004 73 Female 134 lb 3/14/2006 United States
Primary
Concomitant
Sudden Cardiac Death Other Serious 1/14/2006 54 Male 214 lb 3/8/2006 Physician Netherlands
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 1/13/2006 32 Female 168 lb 3/8/2006 Physician Netherlands
Primary
Secondary
Concomitant
Stomatitis Hospitalization 1/23/2006 81 Male 160 lb 3/17/2006 Physician United States
Primary
Secondary
Concomitant
Obstruction Hospitalization 74 Male 3/16/2006 Pharmacist United States
Primary
Secondary
Concomitant
Stomatitis Hospitalization 1/25/2006 81 Male 160 lb 3/23/2006 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 1/13/2006 32 Female 168 lb 3/21/2006 Physician Netherlands
Primary
Secondary
Concomitant
Stomatitis Hospitalization 1/23/2006 81 Male 160 lb 3/31/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Stomatitis Hospitalization 1/25/2006 81 Male 160 lb 4/1/2006 United States
Primary
Secondary
Concomitant
Lymphocyte Count Decreased Hospitalization 10/30/2004 29 Female 121 lb 4/1/2006 United States
Primary
Concomitant
Platelet Count Decreased Hospitalization 1/13/2006 71 Male 137 lb 4/3/2006 Physician France
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Death 10/31/2005 77 Male 4/5/2006 Japan
Primary
Concomitant
White Blood Cell Count Decreased Death 2/28/2006 74 Male 4/11/2006 Physician United States
Primary
Concomitant
Pyrexia Required Intervention 1/4/2006 56 Male 182 lb 2/14/2006 Pharmacist United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 2/17/2006 55 Male 4/20/2006 United States
Primary
Secondary
Concomitant
Stomatitis Hospitalization 1/25/2006 81 Male 160 lb 4/20/2006 United States
Primary
Secondary
Concomitant
Herpes Simplex Other Serious 6/10/2005 26 Female 182 lb 4/19/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Herpes Simplex Hospitalization 6/10/2005 26 Female 182 lb 4/19/2006 United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 2/17/2006 55 Male 4/21/2006 United States
Primary
Secondary
Concomitant
Stomatitis Hospitalization 1/23/2006 81 Male 160 lb 4/21/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Septic Shock Death 4/24/2006 57 Male 245 lb 5/23/2006 Physician United States
Primary
Secondary
Concomitant
Skin Exfoliation Other Serious 46 Female 6/16/2006 Canada
Primary
Secondary
Concomitant
Aspartate Aminotransferase Increased Hospitalization 6/4/2005 26 Female 184 lb 6/5/2006 United States
Primary
Secondary
Concomitant
Neutropenic Infection Hospitalization 5/15/2006 68 Male 148 lb 6/24/2006 Physician United States
Primary
Secondary
Concomitant
Weight Increased Hospitalization 4/13/2006 67 Male 6/29/2006 Physician United States
Primary
Secondary
Concomitant
Septic Shock Death 4/24/2006 57 Male 245 lb 6/29/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Stomatitis Hospitalization 1/25/2006 81 Male 160 lb 7/15/2006 United States
Primary
Secondary
Concomitant
Prothrombin Time Prolonged Life Threatening 3/8/2006 73 Male 5/24/2006 Japan
Primary
Concomitant
White Blood Cell Count Increased Life Threatening 3/8/2006 73 Male 7/11/2006 Japan
Primary
Concomitant
Prothrombin Time Prolonged Life Threatening 3/8/2006 73 Male 7/18/2006 Japan
Primary
Concomitant
White Blood Cell Count Decreased Life Threatening 12/28/2005 58 Male 7/20/2006 Japan
Primary
Concomitant
Skin Exfoliation Other Serious 11/6/2005 46 Female 153 lb 7/25/2006 Canada
Primary
Secondary
Concomitant
Stomatitis Hospitalization 1/23/2006 81 Male 160 lb 7/26/2006 Physician United States
Primary
Secondary
Concomitant
Trichosporon Infection Hospitalization 4/24/2006 57 Male 245 lb 8/1/2006 United States
Primary
Secondary
Concomitant
Sepsis Death 7/16/2006 67 Male 8/2/2006 Physician United States
Primary
Secondary
Concomitant
Tachycardia Hospitalization 3/4/2006 Male 311 lb 8/11/2006 United States
Primary
Secondary
Pneumonia Hospitalization 5/23/2006 68 Male 148 lb 8/10/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Staphylococcal Infection Hospitalization 2/25/2006 59 Male 160 lb 8/12/2006 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 5/15/2006 68 Male 148 lb 8/12/2006 Physician United States
Primary
Secondary
Concomitant
Staphylococcal Infection Hospitalization 2/25/2006 59 Male 160 lb 8/14/2006 United States
Primary
Secondary
Concomitant
Stomatitis Hospitalization 1/23/2006 81 Male 160 lb 8/30/2006 United States
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 3/14/2004 68 Male 168 lb 9/1/2006 United States
Primary
Secondary
Concomitant
Septic Shock Death 64 Female 9/7/2006 Poland
Primary
Concomitant
Pulmonary Oedema Life Threatening 12/7/2004 68 Female 199 lb 9/8/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Sepsis Death 7/16/2006 67 Male 9/6/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Mucosal Inflammation Other Serious 5/23/2006 68 Male 148 lb 9/22/2006 Physician United States
Primary
Secondary
Concomitant
Septic Shock Other Serious 8/27/2004 64 Female 10/2/2006 Poland
Primary
Concomitant
Pneumonia Hospitalization 5/15/2006 68 Male 148 lb 9/27/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Respiratory Rate Increased Death 9/15/2006 59 Female 190 lb 9/27/2006 Other Health Professional Australia
Primary
Secondary
Concomitant
Myelodysplastic Syndrome Death 9/16/2004 73 Male 9/29/2006 Physician Switzerland
Primary
Concomitant
Vomiting Hospitalization 9/29/2006 68 Male 174 lb 10/5/2006 United States
Primary
Secondary
Concomitant
Hepatomegaly Hospitalization 6/26/2006 44 Male 10/19/2006 France
Primary
Secondary
Concomitant
Tongue Disorder Hospitalization 6/26/2006 44 Male 194 lb 10/27/2006 Other Health Professional France
Primary
Secondary
Concomitant
Skin Exfoliation Other Serious 11/6/2005 46 Female 11/8/2006 Pharmacist Canada
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 9/19/2006 68 Male 11/8/2006 Physician United States
Primary
Concomitant
Vitamin B12 Increased Other Serious 9/20/2006 56 Female 141 lb 11/10/2006 Physician United Kingdom
Primary
Concomitant
Tricuspid Valve Incompetence Required Intervention 11/2/2006 64 Male 11/16/2006 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Life Threatening 9/19/2006 68 Male 11/28/2006 Other Health Professional United States
Primary
Concomitant
Venoocclusive Disease Other Serious 10/14/2006 11 Female 60 lb 11/30/2006 Physician Canada
Primary
Concomitant
Stem Cell Transplant Life Threatening 1/5/2007 59 Male 1/30/2007 Other Health Professional Ireland
Primary
Secondary
Concomitant
Staphylococcal Bacteraemia Hospitalization 2/18/2006 55 Male 2/5/2007 United States
Primary
Secondary
Concomitant
Lacunar Infarction Hospitalization 8/8/2006 70 Female 164 lb 2/16/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 9/19/2006 68 Male 2/22/2007 Other Health Professional United States
Primary
Concomitant
Thrombocytopenia Hospitalization 12/9/2006 78 Male 2/22/2007 Other Health Professional United States
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 9/11/2006 78 Male 2/22/2007 Other Health Professional United States
Primary
Concomitant
Lacunar Infarction Hospitalization 8/8/2006 70 Female 164 lb 2/22/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Retinoic Acid Syndrome Hospitalization 11/28/2005 11 Male 128 lb 3/12/2007 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 8/11/2006 56 Male 3/9/2007 United States
Primary
Secondary
Concomitant
Renal Tubular Acidosis Life Threatening 1/5/2007 59 Male 3/13/2007 Other Health Professional Ireland
Primary
Secondary
Concomitant
Vascular Calcification Hospitalization 11/15/2006 82 Female 3/20/2007 Other Health Professional Australia
Primary
Concomitant
Sepsis Hospitalization 11/25/2006 82 Female 3/20/2007 Other Health Professional Australia
Primary
Concomitant
Torsade De Pointes Other Serious 3/6/2007 45 Male 165 lb 3/19/2007 Other Health Professional United States
Primary
Concomitant
Weight Increased Other Serious 4/1/2006 35 Male 3/26/2007 United States
Primary
Secondary
Concomitant
Pain In Extremity 10/4/2006 15 Female 171 lb 1/22/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Tumour Lysis Syndrome 11/28/2006 27 Male 236 lb 1/22/2007 Pharmacist United States
Primary
Secondary
Concomitant
Stomatitis Other Serious 9/13/2006 51 Male 3/29/2007 Japan
Primary
Secondary
Concomitant
Torsade De Pointes Life Threatening 3/8/2007 66 Female 116 lb 3/29/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Stomatitis Other Serious 9/13/2006 51 Male 4/9/2007 Japan
Primary
Secondary
Concomitant
Drug Interaction Other Serious 2/22/2007 14 Male 62 lb 4/12/2007 Other Health Professional Germany
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 8/11/2006 56 Male 4/19/2007 Japan
Primary
Secondary
Concomitant
Stomatitis Other Serious 9/13/2006 51 Male 4/25/2007 United States
Primary
Secondary
Concomitant
Drug Interaction Other Serious 2/22/2007 14 Male 62 lb 5/2/2007 Other Health Professional Germany
Primary
Secondary
Concomitant
Tremor Hospitalization 7/1/2007 66 Female 144 lb 7/30/2007 Physician United States
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 7/1/2007 66 Female 144 lb 8/13/2007 Physician United States
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening Male 9/18/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Metastasis Other Serious 6/6/2007 61 Male 9/19/2007 Physician France
Primary
Concomitant
Pain In Extremity Hospitalization 11/15/2006 82 Female 9/15/2007 Other Health Professional Australia
Primary
Concomitant
Fungal Infection Hospitalization 4/13/2007 9/20/2007 Physician Italy
Primary
Secondary
Concomitant
Fungal Infection Hospitalization 4/13/2007 Male 159 lb 9/21/2007 Physician Italy
Primary
Secondary
Concomitant
Superinfection Hospitalization 11/25/2006 82 Female 9/18/2007 Other Health Professional Australia
Primary
Concomitant
White Blood Cell Count Increased Other Serious 21 Female 8/16/2007 Physician United States
Primary
Secondary
Sepsis Neonatal Hospitalization Male 8/16/2007 Physician United States
Primary
Secondary
Skin Turgor Decreased Hospitalization 2/11/2007 82 Female 9/26/2007 Other Health Professional United States
Primary
Concomitant
Pain In Extremity Hospitalization 11/15/2006 82 Female 10/9/2007 Australia
Primary
Concomitant
Renal Tubular Acidosis Life Threatening 1/5/2007 Male 10/15/2007 Physician Ireland
Primary
Secondary
Concomitant
Hypotension Hospitalization 8/8/2007 72 Female 10/12/2007 Other Health Professional Poland
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Life Threatening 9/23/2007 Male 192 lb 10/17/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Progressive Multifocal Leukoencephalopathy Hospitalization 7/1/2003 Female 128 lb 10/26/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Renal Tubular Acidosis Life Threatening 1/5/2007 Male 10/26/2007 Physician Ireland
Primary
Secondary
Concomitant
Febrile Neutropenia Other Serious 8/23/2006 76 Female 11/27/2006 Other Health Professional United States
Primary
Concomitant
Febrile Neutropenia Other Serious 8/18/2006 64 Female 11/27/2006 Physician United States
Primary
Concomitant
Thrombocytopenia Life Threatening 4/13/2003 64 Male 11/28/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Traumatic Intracranial Haemorrhage Life Threatening 6/30/2007 63 Male 10/4/2007 Physician United States
Primary
Secondary
Concomitant
Tumour Lysis Syndrome Other Serious 1/1/2004 Male 11/8/2007 Other Health Professional Portugal
Primary
Secondary
Concomitant
Systemic Mycosis Other Serious 8/1/2007 Female 112 lb 11/6/2007 Australia
Primary
Secondary
Concomitant
Staphylococcal Bacteraemia Life Threatening 10/7/2007 14 Male 203 lb 11/8/2007 Physician United States
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Other Serious 10/14/2006 11 Female 60 lb 11/8/2007 Physician Canada
Primary
Secondary
Concomitant
Vomiting Other Serious 9/20/2007 72 Male 11/17/2007 United Kingdom
Primary
Concomitant
Tumour Lysis Syndrome Other Serious 47 Male 11/16/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Tumour Lysis Syndrome Hospitalization 47 Female 11/20/2007 Other Health Professional United Kingdom
Primary
Secondary
No Adverse Reaction 4/13/2003 Male 11/30/2007 Australia
Primary
Secondary
Concomitant
Skin Turgor Decreased Hospitalization 2/11/2007 82 Female 11/28/2007 Other Health Professional United States
Primary
Concomitant
Rash Pruritic Hospitalization 11/10/2007 47 Male 197 lb 12/7/2007 Physician Canada
Primary
Secondary
Concomitant
Skin Toxicity Other Serious 11/13/2007 60 Male 238 lb 12/28/2007 Physician United States
Primary
Secondary
Concomitant
Nausea Hospitalization 8/1/2007 72 Female 1/5/2008 Other Health Professional Poland
Primary
Secondary
Concomitant
Skin Ulcer Other Serious 11/13/2007 60 Male 238 lb 1/4/2008 Physician United States
Primary
Secondary
Concomitant
Sepsis Death 12/31/2007 65 Male 239 lb 1/10/2008 Physician United States
Primary
Secondary
Concomitant
Swelling Hospitalization 11/10/2007 Male 197 lb 1/11/2008 United States
Primary
Secondary
Concomitant
Rash Pruritic Hospitalization 11/10/2007 47 Male 197 lb 1/18/2008 Physician Canada
Primary
Secondary
Concomitant
Septic Shock Death 12/31/2007 65 Male 239 lb 1/16/2008 Physician United States
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 12/5/2007 Male 1/25/2008 Belgium
Primary
Concomitant
Sepsis Death 12/31/2007 65 Male 239 lb 1/31/2008 Physician United States
Primary
Secondary
Concomitant
Urinary Incontinence Hospitalization 2/5/2008 3 Male 29 lb 2/26/2008 Other Health Professional Canada
Primary
Concomitant
Hepatitis Death 1/30/2008 Male 159 lb 3/4/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Hepatitis Death 1/30/2008 Male 159 lb 3/27/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 5/19/2007 Male 3/28/2008 Other Health Professional United States
Primary
Secondary
Concomitant

Drug Data