Allopurinol combined with Coumadin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Wheezing Required Intervention Female 1/4/2006 Physician United States
Primary
Concomitant
Blood Glucose Decreased Other Serious 12/28/2005 88 Female 172 lb 1/17/2006 Other Health Professional United States
Primary
Concomitant
Vomiting Hospitalization 12/12/2005 49 Male 257 lb 1/17/2006 Physician United States
Primary
Concomitant
Pyrexia Hospitalization 10/1/2005 75 Female 1/30/2006 Other Health Professional France
Primary
Secondary
Concomitant
Rash Hospitalization 9/12/2005 73 Male 1/31/2006 Pharmacist United States
Primary
Concomitant
Prothrombin Time Prolonged Other Serious 1/23/2006 Male 156 lb 2/6/2006 Physician United States
Primary
Concomitant
Blood Glucose Decreased Other Serious 12/28/2005 88 Female 172 lb 2/7/2006 Other Health Professional United States
Primary
Concomitant
Hyperkalaemia Hospitalization 10/7/2005 70 Male 191 lb 10/12/2005 Pharmacist United States
Primary
Concomitant
Renal Failure Acute Other Serious 1/5/2006 84 Male 2/16/2006 France
Primary
Secondary
Concomitant
Myocardial Infarction Other Serious 1/1/2001 75 Male 181 lb 2/24/2006 Lawyer United States
Primary
Concomitant
Haematochezia Hospitalization 12/15/2005 87 Male 1/11/2006 Other Health Professional United States
Primary
Concomitant
Blood Glucose Increased 1/1/2006 Male 2/27/2006 Consumer United States
Primary
Concomitant
Oral Intake Reduced Other Serious 1/1/2006 78 Male 168 lb 2/22/2006 United States
Primary
Concomitant
Wheezing Required Intervention Female 3/2/2006 Physician United States
Primary
Concomitant
Weight Decreased 1/1/2005 58 Male 302 lb 1/20/2006 Consumer United States
Primary
Concomitant
Tumour Necrosis Hospitalization 2/14/2005 79 Male 173 lb 2/1/2006 Other Health Professional United States
Primary
Concomitant
Wound Infection Other Serious 1/1/1999 83 Male 256 lb 3/16/2006 Physician United States
Primary
Concomitant
Wheezing Required Intervention Female 3/10/2006 Physician United States
Primary
Concomitant
Poor Peripheral Circulation Other Serious 1/1/2005 76 Female 170 lb 3/10/2006 United States
Primary
Concomitant
Renal Failure Other Serious 10/31/2002 63 Male 161 lb 3/20/2006 Lawyer United States
Primary
Concomitant
Weight Increased Hospitalization 9/17/2003 60 Male 287 lb 3/14/2006 United States
Primary
Concomitant
Myocardial Infarction Other Serious 1/1/2002 72 Female 251 lb 3/22/2006 Lawyer United States
Primary
Concomitant
Visual Disturbance Other Serious 3/1/2005 75 Male 3/17/2006 Physician United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 10/31/2002 63 Male 161 lb 3/27/2006 Physician United States
Primary
Concomitant
Visual Disturbance Other Serious 3/1/2005 75 Male 3/21/2006 Physician United States
Primary
Secondary
Concomitant
Wrong Technique In Drug Usage Process Hospitalization 55 Male 3/19/2006 Consumer United States
Primary
Concomitant
Renal Failure Acute Hospitalization 10/31/2002 63 Male 161 lb 4/4/2006 Physician United States
Primary
Concomitant
Swelling Other Serious 1/1/2004 62 Female 143 lb 4/5/2006 Lawyer United States
Primary
Concomitant
Somnolence 12/26/2005 73 Female 116 lb 1/25/2006 Pharmacist United States
Primary
Concomitant
Oedema Peripheral Hospitalization 3/9/2006 Male 3/30/2006 Physician United States
Primary
Concomitant
Visual Disturbance Other Serious 75 Male 3/30/2006 Other Health Professional Germany
Primary
Secondary
Concomitant
Wound Infection Other Serious 10/26/2003 52 Female 4/12/2006 United States
Primary
Concomitant
Epistaxis Hospitalization 2/6/2006 73 Male 4/13/2006 Other Health Professional France
Primary
Concomitant
Interacting
Wound Infection Other Serious 1/1/1999 83 Male 256 lb 4/14/2006 Physician United States
Primary
Concomitant
Post Procedural Complication Other Serious 9/1/2004 56 Male 245 lb 4/24/2006 United States
Primary
Secondary
Concomitant
Ill-defined Disorder Hospitalization 2/6/2006 82 207 lb 3/30/2006 Pharmacist United States
Primary
Secondary
Concomitant
Nausea Female 4/21/2006 Physician United States
Primary
Concomitant
Sinusitis Other Serious 1/7/2005 70 Male 2/21/2006 Physician United States
Primary
Concomitant
Wound Infection Other Serious 1/1/1999 83 Male 256 lb 4/27/2006 Physician United States
Primary
Concomitant
International Normalised Ratio Increased Hospitalization 2/6/2006 73 Male 4/20/2006 Other Health Professional France
Primary
Secondary
Concomitant
Pneumonia Other Serious 4/1/2006 57 Female 200 lb 4/21/2006 Consumer United States
Primary
Secondary
Concomitant
Renal Disorder Other Serious 6/14/2005 57 Female 220 lb 4/21/2006 United States
Primary
Concomitant
Petechiae Required Intervention 4/18/2006 80 Female 176 lb 5/1/2006 Physician United States
Primary
Concomitant
Intestinal Haemorrhage Other Serious Female 140 lb 3/2/2006 United States
Primary
Concomitant
Wound Infection Other Serious 1/1/2003 52 Female 5/8/2006 United States
Primary
Concomitant
Sickle Cell Anaemia With Crisis Other Serious 4/6/2006 35 Female 178 lb 5/9/2006 Pharmacist United States
Primary
Secondary
Concomitant
Myocardial Infarction Hospitalization 5/2/2006 71 Male 249 lb 5/12/2006 Consumer United States
Primary
Secondary
Concomitant
Jaundice Cholestatic Hospitalization 3/28/2006 67 Female 173 lb 5/11/2006 Pharmacist United States
Primary
Concomitant
Myocardial Infarction Death 5/2/2006 Female 250 lb 5/16/2006 Consumer
Primary
Concomitant
Retinopathy Other Serious 3/1/2005 75 Male 5/11/2006 Physician United States
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 9/29/2003 Male 5/16/2006 United States
Primary
Secondary
Concomitant
Stress Other Serious 4/1/2006 35 Female 178 lb 5/20/2006 Pharmacist United States
Primary
Secondary
Concomitant
Periorbital Disorder Hospitalization 4/4/2006 84 Female 5/23/2006 France
Primary
Secondary
Concomitant
Visual Acuity Reduced Other Serious 75 Male 5/24/2006 Other Health Professional Germany
Primary
Secondary
Concomitant
Injection Site Swelling Hospitalization 12/18/2005 Male 5/31/2006 Consumer United States
Primary
Concomitant
Wound Infection Other Serious 4/23/1999 52 Female 6/2/2006 United States
Primary
Concomitant
White Blood Cell Count Increased Life Threatening 3/29/2006 72 Male 229 lb 5/31/2006 Pharmacist United States
Primary
Secondary
Concomitant
Calculus Bladder Hospitalization 3/1/2004 Male 177 lb 6/9/2006 Physician United States
Primary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 5/14/2006 82 Female 137 lb 6/1/2006 Other Health Professional United States
Primary
Concomitant
Vomiting Hospitalization 8/21/1996 Male 11/1/1996 Physician United States
Primary
Secondary
Concomitant
Myocardial Infarction Hospitalization 5/2/2006 71 Male 249 lb 6/14/2006 Consumer United States
Primary
Secondary
Concomitant
Hypoaesthesia Facial 50 Female 247 lb 4/25/2006 Pharmacist United States
Primary
Concomitant
Prothrombin Time Prolonged Hospitalization 5/14/2006 82 Female 137 lb 6/7/2006 Other Health Professional United States
Primary
Concomitant
Tachycardia Required Intervention 4/21/2006 59 Male 159 lb 6/1/2006 Pharmacist United States
Primary
Concomitant
Pulmonary Oedema Other Serious 3/1/2006 Male 110 lb 6/20/2006 Other Health Professional United States
Primary
Concomitant
Wound Infection Other Serious 4/23/1999 52 Female 6/21/2006 United States
Primary
Secondary
Concomitant
Prothrombin Level Decreased Other Serious 1/10/2000 75 Male 6/14/2006 Canada
Primary
Secondary
Concomitant
Myocardial Infarction Hospitalization 5/2/2006 Male 6/22/2006 Physician
Primary
Secondary
Concomitant
Weight Increased Life Threatening Female 331 lb 6/23/2006 Physician United States
Primary
Concomitant
Prothrombin Level Decreased Other Serious 1/25/2000 74 Male 6/21/2006 Canada
Primary
Secondary
Concomitant
Myocardial Infarction Hospitalization 5/2/2006 71 Male 249 lb 7/6/2006 Consumer United States
Primary
Secondary
Concomitant
Myocardial Infarction Hospitalization 5/2/2006 Male 7/7/2006 Physician
Primary
Secondary
Concomitant
Fall Hospitalization 4/4/2006 84 Female 6/29/2006 France
Primary
Secondary
Concomitant
Renal Function Test Abnormal Other Serious 6/14/2005 57 Female 220 lb 6/30/2006 Consumer United States
Primary
Concomitant
Syncope 3/13/2006 85 Male 177 lb 5/24/2006 Physician United States
Primary
Concomitant
Tricuspid Valve Replacement Other Serious 68 Male 215 lb 7/14/2006 Physician United States
Primary
Concomitant
Rash Hospitalization 5/29/2006 81 Male 243 lb 7/14/2006 Pharmacist United States
Primary
Concomitant
Ventricular Tachycardia Hospitalization 52 Female 132 lb 7/13/2006 Pharmacist United States
Primary
Secondary
Concomitant
Heart Rate Abnormal Disability 11/3/2003 65 Male 10/4/2005 Consumer United States
Primary
Concomitant
Pulmonary Toxicity Hospitalization 3/7/2006 83 Male 180 lb 3/22/2006 Physician United States
Primary
Concomitant
Anaemia Hospitalization 5/25/2006 Male 164 lb 7/28/2006 Physician United States
Primary
Concomitant
Speech Disorder Hospitalization 4/4/2006 84 Female 7/24/2006 France
Primary
Secondary
Concomitant
International Normalised Ratio Increased Other Serious 6/1/2005 58 Male 13 lb 8/1/2006 Consumer United States
Primary
Concomitant
International Normalised Ratio Increased Hospitalization 6/14/2005 80 Male 8/1/2006 Pharmacist United States
Primary
Concomitant
Injection Site Haemorrhage Other Serious 10/16/2005 50 Male 229 lb 8/1/2006 Consumer United States
Primary
Concomitant
Headache 9/1/2005 84 Female 95 lb 8/1/2006 Consumer United States
Primary
Concomitant
Rash Pruritic Other Serious 3/1/2005 75 Male 194 lb 8/1/2006 Consumer United States
Primary
Concomitant
Haemorrhage Hospitalization 11/1/2005 81 Male 216 lb 8/1/2006 Consumer United States
Primary
Concomitant
Pallor 1/1/2006 81 Female 201 lb 8/1/2006 Consumer United States
Primary
Concomitant
Platelet Count Decreased 4/1/2006 69 Male 231 lb 8/1/2006 Consumer United States
Primary
Concomitant
Drug Ineffective Male 163 lb 8/4/2006 Physician United States
Primary
Concomitant
Skin Ulcer 2/1/2005 Male 8/8/2006 Consumer United States
Primary
Concomitant
Treatment Noncompliance Required Intervention 5/3/2006 67 Female 8/16/2006 Physician United States
Primary
Concomitant
Therapeutic Response Decreased Other Serious 10/1/2005 52 Male 164 lb 8/24/2006 Physician United States
Primary
Secondary
Concomitant
Blood Erythropoietin Increased Hospitalization 5/25/2006 Male 164 lb 9/6/2006 Physician United States
Primary
Concomitant
Visual Disturbance Other Serious 3/1/2005 76 Male 9/8/2006 Consumer United States
Primary
Secondary
Concomitant
Wrong Technique In Drug Usage Process Disability 8/9/2002 86 Male 194 lb 9/11/2006 Physician United States
Primary
Concomitant
Visual Disturbance Other Serious 3/1/2005 76 Male 9/18/2006 Consumer United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 7/17/2006 73 Male 192 lb 9/12/2006 United States
Primary
Concomitant
Infusion Site Pain Other Serious 1/1/2005 64 Male 142 lb 9/15/2006 United States
Primary
Secondary
Concomitant
Pseudomonas Infection Hospitalization 8/3/2005 66 Female 144 lb 8/5/2005 Other Health Professional United States
Primary
Concomitant
Cerebrovascular Accident Hospitalization 6/18/2006 87 Male 179 lb 10/4/2006 Pharmacist United States
Primary
Concomitant
Oedema Peripheral Other Serious 10/1/2005 52 Male 164 lb 10/4/2006 Physician United States
Primary
Secondary
Concomitant
Muscular Weakness Hospitalization 1/1/2006 86 Male 167 lb 8/16/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Pregnancy Test False Positive Other Serious 9/18/2006 44 Female 10/3/2006 Physician United States
Primary
Concomitant
Weight Decreased Hospitalization 7/18/2006 73 Male 192 lb 10/6/2006 Physician United States
Primary
Concomitant
Myocardial Infarction Death 5/2/2006 Female 250 lb 10/18/2006 Consumer
Primary
Concomitant
International Normalised Ratio Increased Hospitalization 9/12/2006 92 Male 10/11/2006 Other Health Professional France
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 4/10/2006 74 Male 10/16/2006 Pharmacist United States
Primary
Secondary
Concomitant
International Normalised Ratio Increased 5/31/2006 67 Female 207 lb 8/10/2006 Physician United States
Primary
Secondary
Concomitant
Therapy Non-responder Hospitalization 6/1/2006 76 Male 10/9/2006 Physician United States
Primary
Concomitant
Pneumonia Hospitalization 66 Male 10/20/2006 Consumer United States
Primary
Concomitant
Neutropenia Life Threatening 3/18/2006 77 Female 10/27/2006 Italy
Primary
Concomitant
White Blood Cell Count Increased Other Serious 10/3/2006 86 Female 141 lb 10/23/2006 Physician Puerto Rico
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 9/23/2006 59 Male 10/26/2006 United States
Primary
Secondary
Concomitant
Dizziness Hospitalization 79 Male 11/10/2006 Consumer United States
Primary
Concomitant
Hyperpyrexia Other Serious 7/24/2006 49 Male 146 lb 11/6/2006 Physician Italy
Primary
Concomitant
Death Death 10/1/2006 88 Female 11/7/2006 Physician United States
Primary
Concomitant
Wound Infection Other Serious 4/23/1999 52 Female 11/24/2006 United States
Primary
Secondary
Concomitant
Blood Human Chorionic Gonadotropin Increased Other Serious 9/18/2006 44 Female 11/13/2006 Physician United States
Primary
Secondary
Concomitant
Skin Exfoliation Other Serious 8/26/2006 76 Female 11/16/2006 France
Primary
Secondary
Concomitant
Unresponsive To Stimuli Other Serious 11/24/2005 58 Female 229 lb 11/29/2006 United States
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 3/2/2006 70 Male 149 lb 11/7/2006 Physician United States
Primary
Secondary
Concomitant
Mouth Haemorrhage Death 8/4/2005 47 Male 11/22/2006 Pharmacist United States
Primary
Concomitant
Stevens-johnson Syndrome Death 9/19/2006 81 Male 12/7/2006
Primary
Secondary
Concomitant
Gastrointestinal Carcinoma Required Intervention 6/1/2005 70 Male 236 lb 7/7/2006 Other Health Professional United States
Primary
Concomitant
Pneumonia Hospitalization 66 Male 12/18/2006 Consumer United States
Primary
Concomitant
Oedema Peripheral Other Serious 7/24/2006 49 Male 146 lb 12/7/2006 Physician Italy
Primary
Concomitant
Nausea 1/1/2006 Male 12/22/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Chest Pain Other Serious 8/15/2006 77 Female 135 lb 11/16/2006 United States
Primary
Concomitant
Skin Lesion Other Serious 11/7/2006 78 Male 1/11/2007 France
Primary
Secondary
Concomitant
Stevens-johnson Syndrome Death 10/1/2003 62 Male 200 lb 10/20/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Vertigo 9/3/2006 66 Female 176 lb 10/16/2006 Consumer United States
Primary
Concomitant
Oedema Peripheral Other Serious 8/8/2006 64 Female 1/30/2007 Physician United States
Primary
Secondary
Concomitant
Stomach Discomfort Required Intervention 8/1/2006 84 Male 1/29/2007 Physician United States
Primary
Concomitant
Weight Decreased 1/1/2006 72 Male 265 lb 10/16/2006 Consumer United States
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 1/1/2005 68 Male 1/30/2007 Physician Canada
Primary
Secondary
Concomitant
Red Blood Cell Schistocytes Present Other Serious 8/8/2006 64 Female 2/23/2007 Physician United States
Primary
Concomitant
Pulmonary Oedema Life Threatening 2/3/2007 Female 3/5/2007 Physician United States
Primary
Concomitant
Hallucination Hospitalization 12/1/2006 Female 3/7/2007 Other Health Professional United States
Primary
Concomitant
Wound Infection Other Serious 4/23/1999 52 Female 220 lb 3/8/2007 United States
Primary
Concomitant
Pneumonia Hospitalization 11/1/2005 Female 3/14/2007 Consumer United States
Primary
Concomitant
Hallucination Hospitalization 12/1/2006 Female 3/16/2007 Other Health Professional United States
Primary
Concomitant
Renal Tubular Necrosis Other Serious 10/31/2004 75 Male 180 lb 3/20/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombosis Other Serious 9/1/2006 89 Female 3/8/2007 Physician United States
Primary
Concomitant
Urticaria Required Intervention 12/3/2006 57 Male 289 lb 12/14/2006 United States
Primary
Concomitant
Vomiting Other Serious 7/1/2006 62 Male 3/12/2007 Physician United States
Primary
Secondary
Concomitant
Psychomotor Hyperactivity Hospitalization 1/17/2007 81 Male 3/27/2007 Other Health Professional Germany
Primary
Secondary
Concomitant
Stomatitis Hospitalization 2/15/2007 80 Male 3/28/2007 Consumer Italy
Primary
Concomitant
Paraesthesia Death 1/1/2006 68 Male 3/19/2007 Physician United States
Primary
Secondary
Concomitant

Drug Data