Allopurinol combined with Clarithromycin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Melaena Hospitalization 11/8/2005 65 Male 1/27/2006 Pharmacist United States
Primary
Concomitant
Vomiting Hospitalization 2/6/2006 59 Male 128 lb 2/23/2006 Physician Germany
Primary
Secondary
Concomitant
Vomiting Hospitalization 2/6/2006 59 Male 128 lb 3/30/2006 Physician Germany
Primary
Secondary
Concomitant
Sepsis Hospitalization 2/6/2006 59 Male 128 lb 4/5/2006 Physician Germany
Primary
Secondary
Concomitant
Thrombotic Thrombocytopenic Purpura Other Serious 9/8/2005 73 Female 4/20/2006 Physician Japan
Primary
Secondary
Vomiting Hospitalization 2/6/2006 59 Male 128 lb 4/18/2006 Other Health Professional Germany
Primary
Secondary
Concomitant
Toxic Skin Eruption Required Intervention 12/29/2005 49 Female 123 lb 4/21/2006 Physician Spain
Primary
Concomitant
White Blood Cell Count Decreased Death 7/26/2005 66 Male 203 lb 5/3/2006 Physician Hungary
Primary
Secondary
Concomitant
Viral Infection Hospitalization 69 Female 176 lb 6/16/2006 Canada
Primary
Concomitant
Interacting
Myalgia Other Serious 5/15/2006 88 Female 7/21/2006 Other Health Professional United Kingdom
Primary
Concomitant
Rhabdomyolysis Other Serious 52 Male 209 lb 7/21/2006 Other Health Professional United Kingdom
Primary
Concomitant
Myalgia Other Serious 5/15/2006 88 Female 7/28/2006 United Kingdom
Primary
Concomitant
Therapeutic Agent Toxicity Other Serious 7/10/2006 72 Female 8/23/2006 Consumer United Kingdom
Primary
Secondary
Concomitant
Supraventricular Tachycardia Other Serious 7/10/2006 72 Female 8/21/2006 United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 5/4/2006 52 Male 209 lb 8/28/2006 Other Health Professional United Kingdom
Primary
Concomitant
Therapeutic Agent Toxicity Life Threatening 7/10/2006 72 Female 8/28/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Supraventricular Tachycardia Other Serious 7/10/2006 72 Female 8/31/2006 United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 5/4/2006 52 Male 209 lb 9/6/2006 United Kingdom
Primary
Concomitant
Rhinorrhoea Hospitalization 8/8/2006 60 Male 234 lb 9/12/2006 Other Health Professional Poland
Primary
Secondary
Concomitant
Vomiting Hospitalization 2/7/2006 59 Male 128 lb 9/27/2006 Physician Germany
Primary
Secondary
Concomitant
Vomiting Other Serious 10/21/2006 85 Female 12/6/2006 Other Health Professional United Kingdom
Primary
Concomitant
Central Nervous System Lymphoma Hospitalization 70 Female 12/1/2006 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Vomiting Other Serious 10/21/2006 85 Female 12/11/2006 Other Health Professional United Kingdom
Primary
Concomitant
Rhabdomyolysis Other Serious 5/4/2006 52 Male 209 lb 1/22/2007 Other Health Professional United Kingdom
Primary
Concomitant
Volume Blood Decreased Death 12/22/2006 64 Female 2/5/2007 Physician France
Primary
Concomitant
Rash Other Serious 3/1/2006 Male 137 lb 2/13/2007 Physician Japan
Primary
Concomitant
Rhabdomyolysis Hospitalization 1/1/2006 72 Male 3/30/2007 Physician New Zealand
Primary
Secondary
Concomitant
Multi-organ Failure Other Serious 3/2/2007 Male 139 lb 3/30/2007 Physician Japan
Primary
Concomitant
Subdural Haematoma Other Serious 7/30/2005 Male 4/5/2007 Physician Japan
Primary
Secondary
Concomitant
Multi-organ Failure Other Serious 3/2/2007 Male 139 lb 4/25/2007 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 4/13/2007 51 Female 125 lb 5/3/2007 Pharmacist Japan
Primary
Secondary
Concomitant
Rhabdomyolysis Life Threatening 4/16/2007 73 Male 178 lb 4/30/2007 Pharmacist United States
Primary
Secondary
Concomitant
Subdural Haematoma Other Serious 7/30/2005 Male 5/23/2007 Physician Japan
Primary
Secondary
Concomitant
Renal Failure Hospitalization 5/7/2007 79 Male 5/24/2007 Other Health Professional Italy
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 4/13/2007 Female 5/31/2007 Consumer Japan
Primary
Secondary
Concomitant
Pulmonary Embolism Life Threatening 4/8/2007 57 Male 181 lb 5/29/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 54 Female 6/11/2007 Physician Italy
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 2/1/2007 75 Male 6/19/2007 Physician Japan
Primary
Concomitant
Pseudomembranous Colitis Hospitalization 2/1/1999 35 Male 6/26/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Liver Disorder Hospitalization 4/1/2007 Male 88 lb 7/5/2007 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 2/1/2007 75 Male 7/24/2007 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 4/13/2007 51 Female 7/30/2007 Consumer Japan
Primary
Secondary
Concomitant
Rhabdomyolysis Life Threatening 7/5/2007 64 Male 7/31/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Life Threatening 7/5/2007 64 Male 8/6/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Septic Shock Death 66 Male 7/20/2007 France
Primary
Secondary
Rhabdomyolysis Hospitalization 1/1/2006 72 Male 8/16/2007 Physician New Zealand
Primary
Secondary
Concomitant
Rhabdomyolysis Life Threatening 7/5/2007 64 Male 7/30/2007 United Kingdom
Primary
Secondary
Concomitant
Renal Impairment Other Serious 1/1/2006 54 Female 9/19/2007 Other Health Professional Italy
Primary
Concomitant
Interacting
Sepsis Hospitalization 2/6/2006 Male 128 lb 9/21/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Life Threatening 7/5/2007 64 Male 9/24/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Life Threatening 7/5/2007 64 Male 9/27/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 4/6/2007 Male 10/19/2007 Physician United Kingdom
Primary
Concomitant
Rhabdomyolysis Other Serious 12/1/2006 48 Female 10/30/2007 Other Health Professional France
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 4/6/2007 Male 12/18/2007 Physician United Kingdom
Primary
Concomitant
Volume Blood Decreased Death 12/22/2006 64 Female 130 lb 12/28/2007 Physician Japan
Primary
Concomitant
Renal Impairment Other Serious 10/21/2005 67 Male 126 lb 3/18/2008 Japan
Primary
Secondary
Concomitant
Drug Interaction Other Serious 1/22/2008 67 Male 4/8/2008 Other Health Professional France
Primary
Secondary
Concomitant
Cholestasis Hospitalization 3/16/2008 Male 119 lb 4/14/2008 Physician Japan
Primary
Secondary
Concomitant
Pneumonia Hospitalization 11/17/2007 46 Male 143 lb 4/16/2008 Consumer United States
Primary
Secondary
Concomitant
Pneumonia Hospitalization 11/17/2007 Male 143 lb 4/14/2008 Physician Japan
Primary
Secondary
Concomitant
Pseudomembranous Colitis Hospitalization 2/1/1999 35 Male 5/5/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Cholestasis Hospitalization 3/16/2008 Male 119 lb 5/9/2008 Physician Japan
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 71 Male 6/4/2008 Pharmacist United Kingdom
Primary
Concomitant
Pseudomembranous Colitis Hospitalization 2/1/1999 35 Male 6/11/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Renal Failure Chronic Other Serious 5/28/2008 Female 121 lb 6/13/2008 Poland
Primary
Secondary
Concomitant
Vertebral Artery Occlusion Hospitalization 5/28/2008 Female 86 lb 6/18/2008 Physician Japan
Primary
Concomitant
Renal Failure Chronic Other Serious 5/28/2008 74 Female 121 lb 6/26/2008 Other Health Professional Poland
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 11/7/2007 Male 143 lb 6/27/2008 Physician Japan
Primary
Secondary
Concomitant
Ventricular Arrhythmia Other Serious 6/28/2007 41 Female 139 lb 7/1/2008 Physician Japan
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 71 Male 7/8/2008 Pharmacist United Kingdom
Primary
Concomitant
Renal Failure Chronic Other Serious 5/28/2008 Female 121 lb 7/30/2008 Poland
Primary
Secondary
Concomitant
Renal Failure Life Threatening 6/9/2008 78 Female 159 lb 8/5/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Ventricular Tachycardia Other Serious 6/28/2007 41 Female 139 lb 8/1/2008 Physician Japan
Primary
Secondary
Concomitant
Renal Failure Chronic Other Serious 5/28/2008 Female 121 lb 8/12/2008 Poland
Primary
Secondary
Concomitant
Hepatic Function Abnormal Other Serious 12/1/2005 56 Male 128 lb 8/15/2008 Japan
Primary
Secondary
Concomitant
Vomiting Other Serious 10/21/2006 85 Female 8/9/2008 United Kingdom
Primary
Concomitant
Incorrect Dose Administered Hospitalization 6/1/2008 Female 174 lb 8/22/2008 Physician United Kingdom
Primary
Concomitant
Renal Failure Chronic Other Serious 5/28/2008 74 Female 121 lb 8/28/2008 Other Health Professional Poland
Primary
Secondary
Concomitant
Delirium Other Serious 57 Male 9/8/2008 Pharmacist Canada
Primary
Concomitant
Erythema Multiforme Hospitalization 8/13/2008 78 Male 9/25/2008
Primary
Concomitant
Erythema Multiforme Hospitalization 8/13/2008 78 Male 9/30/2008 Other Health Professional United Kingdom
Primary
Concomitant
Erythema Multiforme Hospitalization 8/13/2008 78 Male 9/26/2008 Other Health Professional United Kingdom
Primary
Concomitant
Erythema Multiforme Hospitalization 8/13/2008 78 Male 10/7/2008 Other Health Professional United Kingdom
Primary
Concomitant
Rash Hospitalization 8/13/2008 78 Male 10/2/2008 Other Health Professional United Kingdom
Primary
Concomitant
Drug Toxicity Other Serious 10/28/2008
Primary
Secondary
Pyrexia Other Serious 2/9/2007 Male 11/3/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pyrexia Other Serious 2/9/2007 Male 11/4/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Troponin Increased Life Threatening 6/11/2008 59 Male 174 lb 11/10/2008 Physician Germany
Primary
Secondary
Concomitant
Rash 11/7/2007 74 Male 11/28/2008 Physician Japan
Primary
Concomitant
Thrombocytopenia Life Threatening 6/11/2008 59 Male 174 lb 11/21/2008 Physician Germany
Primary
Secondary
Concomitant
Vomiting Life Threatening 11/16/2008 59 Female 123 lb 12/16/2008 Physician Germany
Primary
Concomitant
Vomiting Life Threatening 11/16/2008 59 Female 123 lb 12/17/2008 Physician Germany
Primary
Concomitant
Toxic Skin Eruption Other Serious 11/14/2008 67 Male 12/12/2008 Japan
Primary
Concomitant
Electrocardiogram Qt Interval Abnormal Other Serious 3/7/2008 71 Male 12/19/2008 Ireland
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 9/18/2008 Male 187 lb 1/14/2009 Physician Portugal
Primary
Concomitant
Sinoatrial Block Life Threatening 8/18/2008 66 Female 198 lb 1/16/2009 Physician Germany
Primary
Secondary
Concomitant
Sinoatrial Block Other Serious 8/18/2008 66 Female 198 lb 1/20/2009 Physician Germany
Primary
Secondary
Concomitant
Interacting
Hypotension Other Serious 12/16/2008 70 Female 1/20/2009 Physician United Kingdom
Primary
Concomitant
Sinoatrial Block Life Threatening 8/18/2008 66 Female 198 lb 1/21/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Hypotension Other Serious 12/16/2008 70 Female 1/21/2009 Other Health Professional United Kingdom
Primary
Concomitant
Sinoatrial Block Other Serious 8/18/2008 66 Female 1/23/2009 Physician United States
Primary
Secondary
Concomitant
Hypotension Other Serious 12/16/2008 70 Female 1/21/2009 Other Health Professional United Kingdom
Primary
Concomitant
Sinoatrial Block Other Serious 8/18/2008 66 Female 1/28/2009 Physician United States
Primary
Secondary
Concomitant
Sinoatrial Block Life Threatening 66 Female 1/26/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Sinoatrial Block Life Threatening 66 Female 1/23/2009 Germany
Primary
Secondary
Concomitant
Toxic Skin Eruption Hospitalization 11/14/2008 67 Male 1/29/2009 Consumer Japan
Primary
Concomitant
Hypotension Other Serious 12/16/2008 70 Female 1/27/2009 United Kingdom
Primary
Concomitant
Sepsis Other Serious 1/26/2009 70 Male 178 lb 2/12/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Sepsis Other Serious 1/26/2009 70 Male 178 lb 3/3/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Sepsis Other Serious 1/26/2009 70 Male 178 lb 3/12/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Pneumonia Other Serious 3/7/2008 71 Male 3/13/2009 Ireland
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 77 Female 4/2/2009 Physician Germany
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Other Serious 11/5/2002 47 Male 195 lb 4/3/2009 Other Health Professional United States
Primary
Concomitant
Rhabdomyolysis Hospitalization 77 Female 4/6/2009 Physician Germany
Primary
Secondary
Concomitant
Epilepsy Hospitalization 3/11/2009 76 Female 132 lb 4/7/2009 Physician Germany
Primary
Secondary
Concomitant
Paralysis Other Serious 12/1/2008 58 Male 4/15/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Paralysis Other Serious 12/1/2008 58 Male 4/22/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Paralysis Other Serious 12/1/2008 58 Male 4/20/2009 United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 9/1/2008 77 Female 4/29/2009 Physician Germany
Primary
Secondary
Concomitant
Paralysis Other Serious 12/1/2008 58 Male 4/29/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Central Nervous System Lymphoma Hospitalization 70 Female 7/2/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Central Nervous System Lymphoma Hospitalization 70 Female 7/2/2009 Consumer United States
Primary
Secondary
Concomitant
Cerebrovascular Accident Hospitalization 70 Female 7/10/2009 United Kingdom
Primary
Secondary
Concomitant
Paralysis Other Serious 58 Male 11/10/2009 Other Health Professional United Kingdom
Primary
Concomitant
Thrombocytopenia Other Serious 11/27/2009 Female 170 lb 12/24/2009 Belgium
Primary
Secondary
Concomitant
Tumour Flare Other Serious 11/27/2009 Female 170 lb 12/30/2009 Belgium
Primary
Secondary
Concomitant
Small Intestinal Haemorrhage Life Threatening 12/23/2008 78 Female 1/22/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Swelling Face Life Threatening 7/1/2008 67 Male 143 lb 2/1/2010 Consumer United Kingdom
Primary
Secondary
Withdrawal Syndrome Other Serious 12/23/2009 63 Male 2/5/2010 Pharmacist United Kingdom
Primary
Concomitant
Weight Decreased Life Threatening 7/9/2008 67 Male 1/29/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Throat Irritation Hospitalization 64 Male 2/23/2010 Germany
Primary
Secondary
Concomitant
Stevens-johnson Syndrome Other Serious 53 Female 2/17/2010 Physician Japan
Primary
Secondary
Cough Other Serious 2/22/2010 Male 3/12/2010 Pharmacist France
Primary
Concomitant
Urine Chloride Decreased Other Serious 16 Male 123 lb 3/10/2010 Other Health Professional Canada
Primary
Concomitant
Stevens-johnson Syndrome Other Serious 53 Female 3/15/2010 Other Health Professional Japan
Primary
Secondary
Rhabdomyolysis Hospitalization 59 Male 6/11/2010 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Multi-organ Failure Death 3/1/2008 52 Male 6/15/2010 Other Health Professional Spain
Primary
Concomitant
Interacting
Drug Eruption Hospitalization 12/23/2008 73 Male 154 lb 6/28/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 59 Male 6/29/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 59 Male 7/6/2010 United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 59 Male 7/8/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 59 Male 8/2/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 59 Male 8/10/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Rhinorrhoea Other Serious 6/1/2009 74 Male 8/11/2010 Physician Japan
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 5/20/2010 76 Male 8/19/2010 Other Health Professional Australia
Primary
Concomitant
Rhabdomyolysis Other Serious 59 Male 8/19/2010 United Kingdom
Primary
Secondary
Concomitant
Rhinorrhoea Other Serious Male 8/31/2010 Physician Japan
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 59 Male 9/10/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Treatment Failure Death 5/18/2009 77 Male 139 lb 11/2/2010 Other Health Professional Japan
Primary
Concomitant
Sinoatrial Block Life Threatening 8/18/2008 66 Female 198 lb 11/29/2010 Physician Germany
Primary
Secondary
Concomitant
Interacting

Drug Data