Allopurinol combined with Ciprofloxacin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Sensation Of Pressure Other Serious 12/29/2005 32 Male 1/16/2006 Canada
Primary
Concomitant
Skin Toxicity Other Serious 1/13/2006 32 Female 183 lb 1/25/2006 Physician Netherlands
Primary
Secondary
Concomitant
Sensation Of Pressure Other Serious 12/29/2005 32 Male 1/26/2006 Canada
Primary
Concomitant
Melaena Hospitalization 11/8/2005 65 Male 1/27/2006 Pharmacist United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 1/13/2006 32 Female 183 lb 2/1/2006 Physician Netherlands
Primary
Secondary
Concomitant
Therapy Non-responder Other Serious 1/13/2006 32 Female 183 lb 2/9/2006 Physician Netherlands
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Death 74 Male 2/13/2006 Canada
Primary
Secondary
Concomitant
Hepatitis Toxic Other Serious 10/18/2005 77 Male 3/2/2006 Physician Spain
Primary
Concomitant
Septic Shock Hospitalization 10/30/2005 51 Male 3/2/2006 Pharmacist New Zealand
Primary
Concomitant
Tumour Lysis Syndrome Hospitalization 2/14/2006 68 Female 168 lb 3/3/2006 Consumer United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 1/13/2006 32 Female 190 lb 2/23/2006 Physician Netherlands
Primary
Secondary
Concomitant
Tumour Lysis Syndrome Hospitalization 2/14/2006 68 Female 168 lb 3/13/2006 Consumer United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 1/13/2006 32 Female 183 lb 3/1/2006 Physician Netherlands
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 5/13/2003 60 Male 203 lb 3/13/2006 United States
Primary
Concomitant
Thrombocytopenia Other Serious 47 Female 220 lb 3/4/2006 Physician United States
Primary
Concomitant
Pyrexia Life Threatening 12/12/2002 74 Male 169 lb 3/14/2006 United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 1/13/2006 32 Female 168 lb 3/8/2006 Physician Netherlands
Primary
Secondary
Concomitant
Tumour Lysis Syndrome Hospitalization 2/14/2006 68 Female 168 lb 3/24/2006 Consumer United States
Primary
Secondary
Concomitant
Anaphylactic Reaction Life Threatening 2/2/2006 65 Male 157 lb 3/31/2006 Physician Germany
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 12/12/2005 74 Male 169 lb 4/11/2006 Physician United States
Primary
Concomitant
Toxic Skin Eruption Other Serious 1/7/2006 64 Male 181 lb 4/18/2006 Physician France
Primary
Concomitant
Toxic Skin Eruption Required Intervention 12/29/2005 49 Female 123 lb 4/21/2006 Physician Spain
Primary
Concomitant
Syncope Other Serious 65 Male 4/28/2006 United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Life Threatening 74 Male 4/28/2006 Canada
Primary
Secondary
Concomitant
Tumour Lysis Syndrome Hospitalization 2/14/2006 68 Female 168 lb 5/15/2006 Consumer United States
Primary
Secondary
Concomitant
Thrombin Time Prolonged Life Threatening 9/7/2005 63 Male 175 lb 5/9/2006 Physician Hungary
Primary
Secondary
Concomitant
Syncope Other Serious 65 Male 5/17/2006 Consumer United Kingdom
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 1/26/2006 70 Male 5/12/2006 Pharmacist United Kingdom
Primary
Concomitant
Transaminases Increased Hospitalization 7/8/2005 61 Female 5/23/2006 Physician Germany
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 3/2/2006 71 Female 5/24/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Syncope Other Serious 65 Male 5/26/2006 Consumer United Kingdom
Primary
Secondary
Concomitant
Troponin I Increased Hospitalization 3/14/2006 84 Male 112 lb 5/22/2006 Physician United Kingdom
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 3/21/2006 76 Male 150 lb 6/7/2006 Physician United States
Primary
Secondary
Concomitant
Prothrombin Level Decreased Other Serious 1/10/2000 75 Male 6/14/2006 Canada
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 3/21/2006 76 Male 150 lb 6/16/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Pleural Effusion Life Threatening 5/17/2006 56 Male 6/15/2006 Germany
Primary
Concomitant
Prothrombin Level Decreased Other Serious 1/25/2000 74 Male 6/21/2006 Canada
Primary
Secondary
Concomitant
Neutrophil Count Decreased Other Serious 56 Male 6/22/2006 United Kingdom
Primary
Secondary
Concomitant
Neutrophil Count Decreased Other Serious 56 Male 6/22/2006 United Kingdom
Primary
Secondary
Concomitant
Septic Shock Death 4/24/2006 57 Male 245 lb 6/29/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Troponin I Increased Hospitalization 3/14/2006 84 Male 112 lb 7/7/2006 Physician United Kingdom
Primary
Concomitant
Stomatitis Hospitalization 6/2/2006 60 Male 7/10/2006 Other Health Professional Italy
Primary
Concomitant
Skin Exfoliation Other Serious 11/6/2005 46 Female 153 lb 7/25/2006 Canada
Primary
Secondary
Concomitant
Capillary Leak Syndrome Hospitalization 5/10/2006 Male 7/31/2006 Physician Spain
Primary
Secondary
Concomitant
Vomiting Life Threatening 12/14/2002 Male 163 lb 8/4/2006 United States
Primary
Secondary
Concomitant
Platelet Count Decreased Other Serious 62 Male 8/1/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Platelet Count Decreased Other Serious 51 Male 8/4/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Sinusitis Other Serious 56 Male 8/25/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Troponin I Increased Hospitalization 3/14/2006 84 Male 112 lb 8/23/2006 Physician United Kingdom
Primary
Concomitant
Ultrasound Abdomen Abnormal Hospitalization 1/1/2006 83 Female 227 lb 9/8/2006 Physician France
Primary
Secondary
Concomitant
Capillary Leak Syndrome Hospitalization 5/10/2006 Male 9/22/2006 Physician Spain
Primary
Secondary
Concomitant
Vomiting Life Threatening 12/14/2002 Male 163 lb 9/29/2006 United States
Primary
Secondary
Concomitant
Tachycardia Hospitalization 8/24/2006 58 Male 9/26/2006 Physician United States
Primary
Secondary
Concomitant
Transplant Rejection Life Threatening 5/17/2006 56 Male 9/25/2006 Germany
Primary
Concomitant
Pancytopenia Other Serious 1/5/2006 70 Male 183 lb 10/3/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 12/14/2002 Male 10/6/2006 Germany
Primary
Concomitant
Transplant Rejection Life Threatening 5/17/2006 56 Male 10/3/2006 Germany
Primary
Concomitant
Cardiac Failure Hospitalization 5/10/2006 Male 10/9/2006 Physician Spain
Primary
Secondary
Concomitant
Visual Acuity Reduced Other Serious 1/1/2006 66 Female 168 lb 10/13/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Granulocytopenia Hospitalization 11/23/2004 63 Male 179 lb 10/17/2006 Other Health Professional Hungary
Primary
Secondary
Concomitant
Intestinal Ischaemia Other Serious 9/11/2006 77 Male 11/2/2006 Other Health Professional Canada
Primary
Concomitant
Tongue Disorder Hospitalization 6/26/2006 44 Male 194 lb 10/27/2006 Other Health Professional France
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 9/19/2006 68 Male 11/8/2006 Physician United States
Primary
Concomitant
Pulmonary Oedema Other Serious 6/30/2006 26 Female 11/13/2006 Other Health Professional United Kingdom
Primary
Concomitant
Hyponatraemia Hospitalization 9/5/2005 73 Female 175 lb 11/21/2006 Other Health Professional Germany
Primary
Secondary
Concomitant
Interacting
Hyponatraemia Other Serious 9/5/2005 73 Female 11/14/2006 Germany
Primary
Secondary
Concomitant
Wound Infection Life Threatening 5/17/2006 56 Male 11/16/2006 Germany
Primary
Concomitant
White Blood Cell Count Decreased Life Threatening 9/19/2006 68 Male 11/28/2006 Other Health Professional United States
Primary
Concomitant
Oedema Hospitalization 9/5/2005 73 Female 12/8/2006 Physician Germany
Primary
Secondary
Concomitant
Toxic Skin Eruption Other Serious 1/7/2006 64 Male 181 lb 1/2/2007 Physician France
Primary
Concomitant
Stevens-johnson Syndrome Death 10/1/2003 62 Male 200 lb 10/20/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Troponin I Increased Life Threatening 1/14/2007 76 Female 150 lb 1/17/2007 Physician Australia
Primary
Secondary
Concomitant
Fall Hospitalization 12/26/2006 Male 2/13/2007 Pharmacist United States
Primary
Concomitant
Troponin I Increased Life Threatening 1/14/2007 76 Female 150 lb 2/15/2007 Physician Australia
Primary
Secondary
Concomitant
Sepsis Hospitalization 1/12/2007 43 Female 2/23/2007 Other Health Professional United Kingdom
Primary
Concomitant
Thrombocytopenia Life Threatening 9/19/2006 68 Male 2/22/2007 Other Health Professional United States
Primary
Concomitant
Sepsis Other Serious 1/12/2007 43 2/28/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Troponin I Increased Life Threatening 1/14/2007 76 Female 150 lb 3/2/2007 Physician Australia
Primary
Secondary
Concomitant
Cardiac Arrest Life Threatening 1/31/2007 73 Female 198 lb 3/21/2007
Primary
Concomitant
Haemolysis Life Threatening 1/24/2007 88 Female 66 lb 3/26/2007 Physician Japan
Primary
Concomitant
Pyrexia Hospitalization 3/26/2006 Male 198 lb 4/3/2007 Germany
Primary
Concomitant
Vomiting Life Threatening 2/12/2007 73 Female 143 lb 3/29/2007 Physician Italy
Primary
Secondary
Concomitant
Transplant Failure Life Threatening 1/1/2006 Male 159 lb 4/16/2007 Physician Germany
Primary
Concomitant
Haemolysis Life Threatening 1/24/2007 88 Female 66 lb 4/24/2007 Physician Japan
Primary
Concomitant
Tachycardia Hospitalization 1/20/2007 62 Female 4/24/2007 Other Health Professional United Kingdom
Primary
Concomitant
Respiratory Arrest Life Threatening 3/27/2007 62 Male 260 lb 5/9/2007 Consumer United States
Primary
Concomitant
Toxic Induced Encephalopathy Other Serious 4/15/2007 78 Male 128 lb 5/18/2007 Physician Switzerland
Primary
Concomitant
Pseudomembranous Colitis Hospitalization 2/1/1999 35 Male 6/26/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Transplant Failure Life Threatening 3/30/2006 Male 159 lb 6/26/2007 Physician Germany
Primary
Concomitant
Toxic Epidermal Necrolysis Required Intervention 59 Male 6/22/2007 Italy
Primary
Concomitant
Tricuspid Valve Incompetence Death 5/29/2007 76 Male 139 lb 7/13/2007 Physician Spain
Primary
Concomitant
Salmonellosis Other Serious 7/1/2007 Male 155 lb 7/23/2007 Consumer United States
Primary
Secondary
Concomitant
Mastication Disorder Hospitalization 84 Male 7/25/2007 Other Health Professional Hong Kong
Primary
Secondary
Concomitant
Renal Failure Hospitalization 4/18/2007 59 Female 209 lb 7/31/2007 Other Health Professional France
Primary
Secondary
Concomitant
Tremor Hospitalization 7/1/2007 66 Female 144 lb 7/30/2007 Physician United States
Primary
Secondary
Concomitant
Hyperkalaemia Hospitalization 3/21/2006 76 Male 150 lb 8/16/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Interacting
Toxic Epidermal Necrolysis Hospitalization 7/1/2007 66 Female 144 lb 8/13/2007 Physician United States
Primary
Secondary
Concomitant
Tachycardia Hospitalization 5/24/2007 55 Male 150 lb 8/16/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 7/5/2007 36 Male 174 lb 8/17/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Renal Failure Hospitalization 4/18/2007 59 Female 209 lb 9/5/2007 Other Health Professional France
Primary
Secondary
Concomitant
Infection Hospitalization 8/30/2007 Female 121 lb 9/13/2007 Germany
Primary
Concomitant
Fungal Infection Hospitalization 4/13/2007 9/20/2007 Physician Italy
Primary
Secondary
Concomitant
Infection Hospitalization 8/30/2007 Female 121 lb 9/20/2007 Germany
Primary
Concomitant
Fungal Infection Hospitalization 4/13/2007 Male 159 lb 9/21/2007 Physician Italy
Primary
Secondary
Concomitant
Splenomegaly Other Serious 2/20/2007 57 Female 137 lb 9/19/2007 Physician Portugal
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Hospitalization 6/21/2007 Male 142 lb 9/21/2007 Other Health Professional United States
Primary
Concomitant
Toxic Epidermal Necrolysis Other Serious 1/1/1997 43 Male 9/18/2007 Italy
Primary
Secondary
White Blood Cell Count Increased Hospitalization 7/1/2007 73 Male 174 lb 9/21/2007 Physician United States
Primary
Concomitant
Venoocclusive Liver Disease Life Threatening 9/23/2007 Male 192 lb 10/17/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Unresponsive To Stimuli Hospitalization 1/6/2007 60 Male 10/12/2007 Physician United States
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 4/6/2007 Male 10/19/2007 Physician United Kingdom
Primary
Concomitant
Rhabdomyolysis Hospitalization 3/9/2007 77 Female 282 lb 10/24/2007 Other Health Professional Australia
Primary
Secondary
Concomitant
Osteonecrosis Hospitalization 12/21/2006 60 Male 10/29/2007 United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 10/17/2007 70 Male 10/31/2007 Other Health Professional United States
Primary
Concomitant
Pneumonia Bacterial Death 6/20/2007 Male 11/10/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Renal Failure Hospitalization 4/18/2007 59 Female 209 lb 11/15/2007 Other Health Professional France
Primary
Secondary
Concomitant
Tendon Rupture Other Serious 10/1/2007 78 Male 165 lb 11/30/2007 Physician Germany
Primary
Concomitant
Gastrointestinal Disorder 7/1/2007 66 Male 190 lb 11/12/2007 Physician United States
Primary
Concomitant
Pneumonia Bacterial Death 6/20/2007 Male 12/7/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Transplant Failure Life Threatening 3/30/2006 Male 159 lb 12/12/2007 Physician Germany
Primary
Concomitant
Ventricular Tachycardia Death 3/5/2007 88 Female 156 lb 12/7/2007 Pharmacist United States
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 4/6/2007 Male 12/18/2007 Physician United Kingdom
Primary
Concomitant
Thrombotic Thrombocytopenic Purpura Death 9/24/2007 46 Female 146 lb 1/24/2008 United Kingdom
Primary
Concomitant
Renal Failure Hospitalization 12/31/2007 Male 216 lb 1/31/2008 Consumer United States
Primary
Concomitant
Renal Failure Hospitalization 12/31/2007 Male 216 lb 2/8/2008 Consumer United States
Primary
Concomitant
Tremor Other Serious 1/1/2005 84 Male 2/5/2008 China
Primary
Concomitant
Toxic Epidermal Necrolysis Other Serious 10/7/2007 73 Male 2/15/2008 Other Health Professional France
Primary
Secondary
Concomitant
Toxic Skin Eruption Hospitalization 1/2/2008 72 Male 2/15/2008 Consumer United Kingdom
Primary
Secondary
White Blood Cell Count Decreased Required Intervention 1/8/2007 57 Male 204 lb 9/7/2007 Physician United States
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 2/7/2008 78 Male 163 lb 2/14/2008 Other Health Professional Italy
Primary
Concomitant
Toxic Skin Eruption Hospitalization 1/2/2008 72 Male 2/22/2008 United Kingdom
Primary
Secondary
Toxic Skin Eruption Hospitalization 1/2/2008 72 Male 2/27/2008 United Kingdom
Primary
Secondary
Toxic Skin Eruption Hospitalization 1/2/2008 72 Male 2/27/2008 Other Health Professional United Kingdom
Primary
Secondary
Toxic Skin Eruption Hospitalization 1/2/2008 72 Male 2/22/2008 Other Health Professional United Kingdom
Primary
Secondary
Toxic Skin Eruption Hospitalization 1/2/2008 72 Male 2/21/2008 United Kingdom
Primary
Secondary
Toxic Skin Eruption Hospitalization 1/2/2008 72 Male 2/26/2008 Other Health Professional United Kingdom
Primary
Secondary
Toxic Skin Eruption 1/2/2008 72 Male 3/5/2008 Other Health Professional United Kingdom
Primary
Secondary
Toxic Skin Eruption Hospitalization 1/2/2008 72 Male 3/5/2008 Other Health Professional United Kingdom
Primary
Secondary
Toxic Epidermal Necrolysis Other Serious 10/7/2007 73 Male 3/7/2008 Other Health Professional France
Primary
Secondary
Concomitant
Pleural Effusion Hospitalization 3/10/2006 59 Male 3/10/2008 Consumer Sweden
Primary
Concomitant
Pleural Effusion Hospitalization 3/10/2006 59 Male 3/12/2008 Consumer Sweden
Primary
Concomitant
Toxic Skin Eruption Hospitalization 1/2/2008 72 Male 3/12/2008 Other Health Professional United Kingdom
Primary
Secondary
Toxic Skin Eruption Hospitalization 1/2/2008 72 Male 3/12/2008 Other Health Professional United Kingdom
Primary
Concomitant
Death Death 3/21/2008 49 Male 172 lb 3/21/2008 Other Health Professional Italy
Primary
Concomitant
Tachycardia Life Threatening 10/11/2007 71 Male 3/27/2008 Other Health Professional United States
Primary
Concomitant
Nephrogenic Systemic Fibrosis Disability 8/12/2000 36 Male 4/11/2008 United Kingdom
Primary
Concomitant
Weight Decreased Hospitalization 2/14/2008 Male 220 lb 4/25/2008 Physician Switzerland
Primary
Concomitant
Tachycardia Life Threatening 2/12/2008 Male 4/30/2008 Other Health Professional France
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 6/21/2007 81 Male 142 lb 5/2/2008 Other Health Professional United States
Primary
Concomitant
Epstein-barr Virus Infection Life Threatening 3/27/2008 53 Female 121 lb 5/8/2008 Other Health Professional Italy
Primary
Concomitant

Drug Data