Allopurinol combined with Bevacizumab

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Somnolence Life Threatening 10/1/2006 68 Male 124 lb 11/20/2006 Physician New Zealand
Primary
Secondary
Concomitant
Wound Dehiscence Life Threatening 10/1/2006 68 Male 147 lb 11/30/2006 Physician New Zealand
Primary
Secondary
Concomitant
Performance Status Decreased Other Serious 10/24/2006 Male 3/21/2007 Physician Austria
Primary
Secondary
Concomitant
Resuscitation Other Serious 10/24/2006 Male 3/29/2007 Physician Austria
Primary
Secondary
Concomitant
Small Intestinal Obstruction Hospitalization 2/1/2007 65 Male 222 lb 4/2/2007 Physician United States
Primary
Secondary
Concomitant
Resuscitation Other Serious 10/24/2006 Male 4/6/2007 Physician Austria
Primary
Secondary
Concomitant
Pulmonary Haemorrhage Life Threatening 8/16/2006 Female 237 lb 4/18/2007 United States
Primary
Secondary
Concomitant
Death Death 11/2/2006 Female 195 lb 4/18/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Nerve Root Compression Hospitalization 3/27/2007 53 Female 4/23/2007 Consumer United States
Primary
Secondary
Concomitant
Tachyarrhythmia Death 11/2/2006 Female 195 lb 4/26/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Stevens-johnson Syndrome Hospitalization 4/28/2007 Female 5/9/2007 Consumer United States
Primary
Concomitant
Multi-organ Failure Death 11/2/2006 Female 195 lb 5/15/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Stevens-johnson Syndrome Hospitalization 4/28/2007 Female 5/31/2007 Consumer United States
Primary
Concomitant
Colitis Hospitalization 1/11/2007 68 Male 5/25/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Diarrhoea Hospitalization 3/24/2007 77 Male 236 lb 6/5/2007 Consumer United States
Primary
Secondary
Concomitant
Hypertension Other Serious Female 6/8/2007 Physician United States
Primary
Concomitant
Stevens-johnson Syndrome Hospitalization 4/28/2007 Female 6/11/2007 Consumer United States
Primary
Concomitant
Hepatic Failure Hospitalization 5/29/2007 Male 232 lb 6/13/2007 Physician United States
Primary
Secondary
Concomitant
Hydronephrosis Hospitalization 6/2/2005 Male 6/21/2007 Consumer Switzerland
Primary
Secondary
Concomitant
Epilepsy Other Serious 5/28/2007 Male 216 lb 6/25/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 5/28/2007 Male 216 lb 7/6/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Resuscitation Other Serious 10/24/2006 Male 7/23/2007 Physician Austria
Primary
Secondary
Concomitant
Epilepsy Hospitalization 5/28/2007 Male 216 lb 7/23/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Nervous System Disorder Other Serious 6/10/2007 Male 201 lb 9/7/2007 Physician United States
Primary
Secondary
Concomitant
Peripheral Sensory Neuropathy Hospitalization 8/31/2007 67 Male 9/10/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Haemorrhage Hospitalization 7/29/2007 Male 204 lb 9/11/2007 Physician United States
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening Male 9/18/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Haemorrhage Hospitalization 7/29/2007 Male 204 lb 9/19/2007 Physician United States
Primary
Secondary
Concomitant
Peripheral Sensory Neuropathy Hospitalization 8/31/2007 67 Male 9/27/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Subarachnoid Haemorrhage Hospitalization 7/29/2007 Male 204 lb 10/11/2007 Physician United States
Primary
Secondary
Concomitant
Stent Occlusion Life Threatening 10/16/2006 64 Male 10/15/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Resuscitation Other Serious 10/24/2006 Male 11/7/2007 Physician Austria
Primary
Secondary
Concomitant
Death Death 11/13/2007 Male 130 lb 12/6/2007 Consumer United Kingdom
Primary
Concomitant
Visual Acuity Reduced Disability 5/29/2007 Male 12/21/2007 Consumer Canada
Primary
Secondary
Concomitant
Thrombotic Microangiopathy Other Serious 85 Female 12/22/2007 Physician United States
Primary
Secondary
Concomitant
Thrombotic Microangiopathy Other Serious 85 Female 1/15/2008 Physician United States
Primary
Secondary
Concomitant
Proteinuria Hospitalization 12/27/2007 Male 179 lb 1/24/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Death Death 12/26/2007 63 Male 188 lb 2/1/2008 Consumer United States
Primary
Concomitant
Microangiopathic Haemolytic Anaemia Other Serious 57 Female 2/21/2008 Physician United States
Primary
Secondary
Concomitant
Hepatitis Death 1/30/2008 Male 159 lb 3/4/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Performance Status Decreased Other Serious 10/24/2006 Male 3/6/2008 Physician Austria
Primary
Secondary
Concomitant
Hypokalaemia Life Threatening 2/4/2008 Female 3/17/2008 Physician United Kingdom
Primary
Concomitant
Hepatitis Death 1/30/2008 Male 159 lb 3/27/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Cerebral Haemorrhage Other Serious 6/10/2007 Male 201 lb 4/4/2008 Physician United States
Primary
Secondary
Concomitant
Cerebral Haemorrhage Hospitalization 7/29/2007 Male 204 lb 4/4/2008 Physician United States
Primary
Secondary
Concomitant
Anaemia Hospitalization 2/14/2008 Male 168 lb 4/10/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 4/1/2008 70 Male 4/14/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 4/1/2008 70 Male 4/14/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Failure Life Threatening 2/4/2008 Female 4/17/2008 Physician United Kingdom
Primary
Concomitant
Febrile Neutropenia Hospitalization 4/1/2008 Male 4/21/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 4/1/2008 Male 4/21/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Systemic Inflammatory Response Syndrome Death 4/7/2008 Male 163 lb 5/6/2008 Physician Germany
Primary
Secondary
Concomitant
Systemic Inflammatory Response Syndrome Hospitalization 3/20/2008 Male 163 lb 5/8/2008 Physician Germany
Primary
Secondary
Concomitant
Multi-organ Failure Hospitalization 3/20/2008 Male 163 lb 5/13/2008 Consumer Germany
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 4/1/2008 Male 5/16/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 4/1/2008 Male 5/16/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Mucosal Inflammation Hospitalization 3/27/2008 57 Male 151 lb 5/16/2008 Physician United States
Primary
Concomitant
Systemic Inflammatory Response Syndrome Hospitalization 3/20/2008 Male 163 lb 5/27/2008 Physician Germany
Primary
Secondary
Concomitant
Renal Failure Life Threatening 2/4/2008 Female 5/27/2008 Physician United Kingdom
Primary
Concomitant
Multi-organ Failure Hospitalization 3/20/2008 Male 163 lb 6/3/2008 Consumer Germany
Primary
Secondary
Concomitant
Pyrexia Hospitalization 4/27/2008 57 Male 6/10/2008 Physician United States
Primary
Concomitant
Intestinal Obstruction Hospitalization 5/18/2008 Male 6/20/2008 Physician Canada
Primary
Secondary
Concomitant
Intestinal Obstruction Hospitalization 5/18/2008 Male 6/26/2008 Physician Canada
Primary
Secondary
Concomitant
Intestinal Obstruction Hospitalization 5/18/2008 Male 6/26/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Pyrexia Hospitalization 6/18/2008 Male 7/3/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Pyrexia Hospitalization 4/27/2008 57 Male 7/3/2008 Physician United States
Primary
Concomitant
Mucosal Inflammation Hospitalization 3/27/2008 57 Male 151 lb 7/7/2008 Physician United States
Primary
Concomitant
Intestinal Obstruction Hospitalization 5/18/2008 Male 7/7/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Pyrexia Hospitalization 6/18/2008 Male 7/10/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Pyrexia Hospitalization 6/18/2008 Male 7/17/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Ultrasound Scan Abnormal Hospitalization 6/18/2008 Male 8/20/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Convulsion Hospitalization 10/15/2008 Female 11/13/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Convulsion Hospitalization 10/15/2008 Female 12/10/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Hyponatraemia Hospitalization 10/21/2008 Male 158 lb 12/17/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Hyponatraemia Hospitalization 10/21/2008 Male 158 lb 1/16/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Hospitalization 59 Male 1/22/2009 Other Health Professional Netherlands
Primary
Concomitant
Hyponatraemia Hospitalization 10/21/2008 Male 158 lb 2/4/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Stomatitis Other Serious 2/5/2009 Female 2/25/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
C-reactive Protein Increased Hospitalization 4/10/2008 3/2/2009 Physician Germany
Primary
Secondary
Concomitant
C-reactive Protein Increased Hospitalization 4/10/2008 71 Male 139 lb 3/11/2009 Physician Germany
Primary
Secondary
Concomitant
Microangiopathic Haemolytic Anaemia Other Serious 57 Female 3/26/2009 Physician United States
Primary
Secondary
Concomitant
Hyponatraemia Hospitalization 10/21/2008 Male 158 lb 3/27/2009 Other Health Professional United States
Primary
Secondary
Concomitant
General Physical Health Deterioration Hospitalization 12/27/2008 Male 4/13/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Circulatory Collapse Hospitalization 3/18/2009 4/15/2009 Physician Germany
Primary
Secondary
Concomitant
Unevaluable Event Hospitalization 8/8/2008 Female 4/16/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Drug Hypersensitivity Hospitalization 4/3/2009 4/17/2009 Physician Germany
Primary
Secondary
Concomitant
Hypertensive Crisis Life Threatening 1/19/2009 Male 4/22/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Peripheral Ischaemia Other Serious 5/10/2009 Male 144 lb 5/18/2009 Consumer United States
Primary
Secondary
Concomitant
Vertigo Other Serious 5/13/2009 Female 157 lb 5/26/2009 Physician Poland
Primary
Secondary
Concomitant
Peripheral Ischaemia Other Serious 5/10/2009 Male 144 lb 6/5/2009 Consumer United States
Primary
Secondary
Concomitant
Vertigo Hospitalization 5/13/2009 Female 6/10/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Renal Impairment Other Serious 6/2/2009 Female 7/28/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Prurigo Hospitalization 7/22/2009 Female 194 lb 8/5/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Nasal Septal Operation Hospitalization 7/30/2009 Female 161 lb 8/13/2009 Physician Poland
Primary
Secondary
Concomitant
Pneumonia Fungal Other Serious 11/28/2008 Male 311 lb 8/17/2009 Physician Germany
Primary
Secondary
Concomitant
Pneumonia Fungal Other Serious 11/28/2008 Male 311 lb 8/19/2009 Physician United States
Primary
Secondary
Concomitant
Prurigo Hospitalization 7/22/2009 Female 194 lb 8/20/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Nasal Septal Operation Hospitalization 7/30/2009 Female 8/20/2009 Consumer United States
Primary
Secondary
Concomitant
Nasal Septum Disorder Hospitalization 7/30/2009 Female 161 lb 9/2/2009 Physician Poland
Primary
Secondary
Concomitant
Nasal Septum Disorder Hospitalization 7/30/2009 Female 161 lb 9/4/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Nasal Septum Disorder Hospitalization 7/30/2009 Female 9/10/2009 Consumer United States
Primary
Secondary
Concomitant
Intestinal Obstruction Hospitalization 6/5/2008 Male 190 lb 11/4/2009 Physician Canada
Primary
Secondary
Concomitant
Troponin I Increased Other Serious 11/3/2009 Male 152 lb 11/6/2009 Physician Chile
Primary
Secondary
Concomitant
Angina Unstable Other Serious 11/3/2009 Male 152 lb 11/10/2009 Physician Chile
Primary
Secondary
Concomitant
Intestinal Obstruction Hospitalization 6/5/2008 Male 11/10/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Angina Unstable Other Serious 11/3/2009 Male 152 lb 11/11/2009 Physician Chile
Primary
Secondary
Concomitant
Angina Unstable Life Threatening 11/3/2009 Male 11/17/2009 Physician United States
Primary
Secondary
Concomitant
Haemorrhoids Other Serious 11/2/2009 Male 176 lb 11/23/2009 Physician Poland
Primary
Secondary
Concomitant
Haemorrhoids Other Serious 11/2/2009 Male 176 lb 11/30/2009 Physician Poland
Primary
Secondary
Concomitant
Haemorrhoids Hospitalization 7/31/2009 Male 12/3/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Convulsion Hospitalization 10/18/2009 Male 12/23/2009 Physician United States
Primary
Secondary
Concomitant
Cerebrovascular Accident Hospitalization 12/8/2009 Male 212 lb 12/23/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Hospitalization 10/18/2009 58 Male 1/4/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Ischaemic Stroke Hospitalization 12/7/2009 Male 212 lb 1/8/2010 Physician United States
Primary
Secondary
Concomitant
Ischaemic Stroke Hospitalization 12/7/2009 Male 212 lb 1/11/2010 Physician United States
Primary
Secondary
Concomitant
Ischaemic Stroke Hospitalization 12/7/2009 Male 212 lb 1/26/2010 Physician United States
Primary
Secondary
Concomitant
Angina Unstable Other Serious 11/3/2009 Male 152 lb 2/1/2010 Physician Chile
Primary
Secondary
Concomitant
Renal Impairment Other Serious 6/2/2009 Female 134 lb 2/2/2010 Physician Sweden
Primary
Secondary
Concomitant
Proctitis Hospitalization 1/30/2009 74 Female 2/9/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Ischaemic Stroke Hospitalization 12/7/2009 Male 212 lb 3/2/2010 Physician United States
Primary
Secondary
Concomitant
Gastritis Hospitalization 9/21/2009 Female 176 lb 3/11/2010 Physician Germany
Primary
Secondary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 1/31/2009 Male 151 lb 3/15/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Dehydration Hospitalization 3/23/2010 71 Male 209 lb 3/31/2010 Physician United States
Primary
Secondary
Concomitant
Dehydration Hospitalization 3/23/2010 71 Male 209 lb 4/2/2010 Physician United States
Primary
Secondary
Concomitant
Cerebral Infarction Hospitalization 3/5/2010 73 Male 108 lb 4/28/2010 Physician Australia
Primary
Secondary
Concomitant
Ischaemic Stroke Hospitalization 12/7/2009 72 Male 212 lb 5/11/2010 Physician United States
Primary
Secondary
Concomitant
Diarrhoea Other Serious 3/9/2010 68 Female 130 lb 5/11/2010 Physician United States
Primary
Secondary
Concomitant
Renal Impairment Other Serious 6/2/2009 47 Female 134 lb 5/12/2010 Physician Sweden
Primary
Secondary
Concomitant
Neuropathy Peripheral Hospitalization 9/22/2009 60 Female 150 lb 5/18/2010 Physician Hungary
Primary
Secondary
Concomitant
Ischaemic Stroke Hospitalization 12/7/2009 72 Male 5/11/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Diarrhoea Other Serious 3/9/2010 68 Female 130 lb 6/17/2010 Physician United States
Primary
Secondary
Concomitant
Diarrhoea Other Serious 3/9/2010 68 Female 130 lb 7/8/2010 Physician United States
Primary
Secondary
Concomitant
Dehydration Hospitalization 3/23/2010 71 Male 209 lb 7/12/2010 Physician United States
Primary
Secondary
Concomitant
Wound Dehiscence Hospitalization 6/22/2010 64 Male 7/13/2010 Physician Belgium
Primary
Secondary
Concomitant
Mucosal Inflammation Hospitalization 5/7/2010 68 Male 168 lb 8/3/2010 Physician Germany
Primary
Secondary
Concomitant
Fistula Hospitalization 6/22/2010 64 Male 8/4/2010 Physician Belgium
Primary
Secondary
Concomitant
Acute Respiratory Distress Syndrome Death 7/27/2010 70 Male 231 lb 8/4/2010 Physician United States
Primary
Secondary
Concomitant
Acute Respiratory Distress Syndrome Death 7/27/2010 70 Male 231 lb 8/11/2010 Physician United States
Primary
Secondary
Concomitant
Acute Respiratory Distress Syndrome Death 7/27/2010 70 Male 231 lb 8/26/2010 Physician United States
Primary
Secondary
Concomitant
Haemorrhage Hospitalization 10/4/2010 75 Male 10/27/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Quality Of Life Decreased Hospitalization 6/22/2010 72 Male 191 lb 11/9/2010 Consumer United States
Primary
Secondary
Concomitant
Quality Of Life Decreased Hospitalization 6/22/2010 72 Male 191 lb 11/15/2010 Physician United States
Primary
Secondary
Concomitant
Haemorrhagic Stroke Hospitalization 10/4/2010 75 Male 11/11/2010 Physician United States
Primary
Secondary
Concomitant
Inappropriate Antidiuretic Hormone Secretion Hospitalization 10/31/2008 52 Male 12/3/2010 Physician United States
Primary
Secondary
Concomitant
Hyperbilirubinaemia Hospitalization 6/22/2010 72 Male 191 lb 12/13/2010 Consumer United States
Primary
Secondary
Concomitant
General Physical Health Deterioration Hospitalization 12/5/2010 69 Male 176 lb 12/15/2010 Physician Germany
Primary
Secondary
Concomitant
Vertigo Hospitalization 1/2/2011 70 Male 209 lb 1/13/2011 Physician Germany
Primary
Secondary
Concomitant
Asthenia Hospitalization Female 157 lb 1/18/2011 Physician Germany
Primary
Secondary
Concomitant
Vertigo Hospitalization 1/2/2011 70 Male 209 lb 1/20/2011 Physician Germany
Primary
Secondary
Concomitant
Asthenia Hospitalization 11/23/2010 60 Female 157 lb 2/1/2011 Physician Germany
Primary
Secondary
Concomitant

Drug Data