Allopurinol combined with Amphotericin B

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Venoocclusive Disease Life Threatening 11/23/2005 63 Female 121 lb 1/12/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Life Threatening 7/5/2001 34 Male 2/8/2006 United Kingdom
Primary
Concomitant
Sepsis Other Serious 12/16/2005 46 Female 2/28/2006 Physician Brazil
Primary
Concomitant
Respiratory Distress Life Threatening 8/19/2005 66 Male 3/1/2006 Physician Switzerland
Primary
Secondary
Concomitant
Sepsis Other Serious 12/16/2005 46 Female 3/13/2006 Physician Brazil
Primary
Concomitant
Transaminases Increased Hospitalization 7/8/2005 61 Female 4/25/2006 Physician Germany
Primary
Secondary
Concomitant
Transaminases Increased Hospitalization 7/8/2005 61 Female 5/23/2006 Physician Germany
Primary
Secondary
Concomitant
Septic Shock Death 4/24/2006 57 Male 245 lb 5/23/2006 Physician United States
Primary
Secondary
Concomitant
Tachycardia Life Threatening 6/1/2005 69 Male 154 lb 6/20/2006 Other Health Professional Germany
Primary
Secondary
Concomitant
Sepsis Life Threatening 5/19/2005 69 Male 154 lb 6/20/2006 Physician Germany
Primary
Secondary
Concomitant
Leukopenia Other Serious 7/5/1999 Male 7/6/2006 Physician Japan
Primary
Secondary
Concomitant
Septic Shock Death 4/24/2006 57 Male 245 lb 6/29/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Trichosporon Infection Hospitalization 4/24/2006 57 Male 245 lb 8/1/2006 United States
Primary
Secondary
Concomitant
Vitamin B12 Increased Other Serious 9/20/2006 56 Female 141 lb 11/10/2006 Physician United Kingdom
Primary
Concomitant
Venoocclusive Disease Other Serious 10/14/2006 11 Female 60 lb 11/30/2006 Physician Canada
Primary
Concomitant
Acute Generalised Exanthematous Pustulosis Hospitalization 68 Male 8/17/2007 Consumer United States
Primary
Concomitant
Toxic Epidermal Necrolysis Other Serious 1/1/1997 43 Male 9/18/2007 Italy
Primary
Secondary
Stomatitis Other Serious 2/23/2007 63 Male 10/22/2007 Physician Japan
Primary
Concomitant
Systemic Mycosis Other Serious 8/1/2007 Female 112 lb 11/6/2007 Australia
Primary
Secondary
Concomitant
Staphylococcal Bacteraemia Life Threatening 10/7/2007 14 Male 203 lb 11/8/2007 Physician United States
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 12/18/2002 76 Male 2/26/2008 Physician Germany
Primary
Secondary
Hepatitis Death 1/30/2008 Male 159 lb 3/4/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 11/1/2002 Male 3/3/2008 Physician Germany
Primary
Secondary
Swollen Tongue Death 11/4/2004 Female 3/14/2008 Germany
Primary
Secondary
Concomitant
Hepatitis Death 1/30/2008 Male 159 lb 3/27/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Stomatitis Other Serious 2/20/2007 63 Male 3/31/2008 Physician Japan
Primary
Concomitant
Swollen Tongue Death 11/4/2004 Female 4/18/2008 Germany
Primary
Secondary
Concomitant
General Physical Health Deterioration Other Serious 7/1/2005 58 Male 143 lb 4/27/2008 Physician United States
Primary
Concomitant
Wound Infection Staphylococcal Life Threatening 11/8/2007 20 Male 118 lb 5/22/2008 Consumer United States
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Life Threatening 11/8/2007 20 Male 118 lb 7/1/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Sudden Death Other Serious 8/6/2008 Female 118 lb 8/26/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 8/17/2008 75 Female 176 lb 9/9/2008 Other Health Professional Germany
Primary
Secondary
Concomitant
Pneumonitis Other Serious 8/6/2008 Female 118 lb 9/19/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Stevens-johnson Syndrome Hospitalization 9/13/1996 Male 190 lb 10/3/2008 Physician Germany
Primary
Secondary
Concomitant
Pyrexia Other Serious 2/9/2007 Male 11/3/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pyrexia Other Serious 2/9/2007 Male 11/4/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Hallucinations, Mixed Other Serious 12/7/2008 Female 93 lb 1/5/2009 Physician Thailand
Primary
Secondary
Concomitant
Hallucinations, Mixed Other Serious 12/7/2008 1/21/2009 Physician Thailand
Primary
Secondary
Concomitant
Pneumonia Cryptococcal Hospitalization 11/22/2008 Male 220 lb 2/9/2009 United States
Primary
Secondary
Concomitant
Drug Rash With Eosinophilia And Systemic Symptoms Hospitalization 10/3/2008 2/11/2009 Other Health Professional France
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Death 12/3/2008 55 Male 158 lb 2/24/2009 Physician United States
Primary
Secondary
Concomitant
Sepsis Life Threatening 2/9/2009 Male 172 lb 3/25/2009 Germany
Primary
Secondary
Concomitant
Sepsis Life Threatening 2/9/2009 Male 172 lb 4/1/2009 Germany
Primary
Secondary
Concomitant
Sepsis Life Threatening 2/9/2009 Male 172 lb 4/13/2009 Germany
Primary
Secondary
Concomitant
Sepsis Other Serious 2/9/2009 Male 4/20/2009 Physician Germany
Primary
Secondary
Concomitant
Seborrhoeic Dermatitis Other Serious 12/1/2008 57 Male 119 lb 4/24/2009 Physician Germany
Primary
Secondary
Concomitant
Renal Failure Other Serious 7/11/2007 79 Male 159 lb 4/21/2009 Physician Italy
Primary
Secondary
Concomitant
Sepsis Life Threatening 2/9/2009 Male 172 lb 5/6/2009 Germany
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 7/11/2007 79 Male 159 lb 5/12/2009 Physician Italy
Primary
Secondary
Concomitant
Sepsis Life Threatening 2/9/2009 Male 172 lb 6/1/2009 Germany
Primary
Secondary
Concomitant
Sepsis Other Serious 2/9/2009 Male 6/8/2009 Physician Germany
Primary
Secondary
Concomitant
Sepsis Life Threatening 2/9/2009 Male 172 lb 7/14/2009 Germany
Primary
Secondary
Concomitant
Sepsis Other Serious 2/9/2009 Male 7/16/2009 Physician Germany
Primary
Secondary
Concomitant
Pulmonary Function Test Abnormal Other Serious 47 Male 9/3/2009 Pharmacist Australia
Primary
Secondary
Concomitant
Respiratory Disorder Other Serious 6/14/2007 47 Male 9/17/2009 Pharmacist Australia
Primary
Secondary
Concomitant
Sepsis Life Threatening 2/9/2009 Male 172 lb 10/7/2009 Germany
Primary
Secondary
Concomitant
Hepatotoxicity Death 9/21/2009 33 Female 12/22/2009 Pharmacist Spain
Primary
Concomitant
Thrombocytopenia Life Threatening 12/15/2009 67 Male 238 lb 12/23/2009 Physician Germany
Primary
Secondary
Concomitant
Weight Decreased Life Threatening 7/5/2005 Male 143 lb 1/26/2010 Physician United Kingdom
Primary
Secondary
Swelling Face Life Threatening 7/1/2008 67 Male 143 lb 2/1/2010 Consumer United Kingdom
Primary
Secondary
Weight Decreased Life Threatening 7/9/2008 67 Male 1/29/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Life Threatening 4/21/2009 65 Female 2/18/2010 Physician Germany
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Life Threatening 4/21/2009 65 Female 2/22/2010 Physician Germany
Primary
Secondary
Concomitant
Seborrhoeic Dermatitis Other Serious 12/1/2008 57 Male 119 lb 3/10/2010 Physician Germany
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Life Threatening 11/8/2007 20 Male 118 lb 3/12/2010 Physician United States
Primary
Secondary
Concomitant
Arrhythmia Death 3/10/2010 56 Female 128 lb 3/26/2010 Physician Germany
Primary
Concomitant
Toxic Epidermal Necrolysis Other Serious 12/2/2002 Male 3/29/2010 Germany
Primary
Secondary
Arrhythmia Death 3/10/2010 56 Female 128 lb 4/9/2010 Physician Germany
Primary
Concomitant
Rash Erythematous Other Serious 4/2/2010 64 Female 176 lb 4/21/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Seborrhoeic Dermatitis Other Serious 12/1/2008 57 Male 119 lb 5/5/2010 Physician Germany
Primary
Secondary
Concomitant
General Physical Health Deterioration Hospitalization 6/8/2010 62 Female 6/15/2010 Physician Germany
Primary
Concomitant
Wound Infection Staphylococcal Life Threatening 11/8/2007 20 Male 118 lb 6/30/2010 Physician United States
Primary
Secondary
Concomitant
General Physical Health Deterioration Hospitalization 6/8/2010 62 Female 7/22/2010 Physician Germany
Primary
Concomitant
Mucosal Inflammation Hospitalization 5/7/2010 68 Male 168 lb 8/3/2010 Physician Germany
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Life Threatening 11/8/2007 20 Male 118 lb 8/6/2010 Physician United States
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Life Threatening 11/8/2007 20 Male 118 lb 8/18/2010 Physician United States
Primary
Secondary
Concomitant
Multi-organ Failure Hospitalization 7/12/2010 77 Female 10/19/2010 Physician Germany
Primary
Concomitant
Pneumonia Fungal Other Serious 5/18/2010 5 Female 57 lb 12/22/2010 Physician United States
Primary
Secondary
Concomitant
Palpitations Other Serious 3/15/2004 45 Male 139 lb 12/22/2010 Physician Japan
Primary
Concomitant
Bone Marrow Failure Death 5/18/2010 5 Female 57 lb 1/5/2011 Physician United States
Primary
Secondary
Concomitant
Hodgkin's Disease Nodular Sclerosis Stage Iv Hospitalization 1/1/2010 52 Female 1/19/2011 Physician Germany
Primary
Concomitant
Fatigue Other Serious 1/1/2010 52 Female 1/20/2011 Physician Germany
Primary
Concomitant
Nasopharyngitis Death 1/22/2008 66 Female 1/24/2011 Physician Germany
Primary
Concomitant
Haematoma Hospitalization 9/1/2010 81 Female 117 lb 2/14/2011 Physician Germany
Primary
Concomitant
Bone Marrow Failure Other Serious 3/10/2010 62 Male 280 lb 2/18/2011 Physician Germany
Primary
Concomitant
Bone Marrow Failure Other Serious 3/10/2010 62 Male 280 lb 4/6/2011 Other Health Professional Germany
Primary
Concomitant
Fungal Skin Infection Hospitalization 5/18/2010 5 Female 57 lb 4/12/2011 Physician United States
Primary
Secondary
Concomitant
Vertigo Hospitalization 2/9/2011 67 Male 157 lb 4/18/2011 Consumer United States
Primary
Secondary
Concomitant
Vertigo Hospitalization 2/9/2011 67 Male 157 lb 4/27/2011 Consumer United States
Primary
Secondary
Concomitant
Anaphylactic Reaction Hospitalization 4/3/2010 16 Female 95 lb 5/4/2011 Physician Japan
Primary
Secondary
Concomitant
Radiation Oesophagitis Hospitalization 2/9/2011 67 Male 157 lb 5/6/2011 Consumer United States
Primary
Secondary
Concomitant
Pneumonia Primary Atypical Hospitalization 4/2/2011 72 Male 168 lb 5/9/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Metastases To Bone Death 9/1/2010 65 Male 6/1/2011 Other Health Professional Germany
Primary
Concomitant
Bone Marrow Failure Death 3/10/2010 62 Male 280 lb 6/16/2011 Other Health Professional Germany
Primary
Concomitant
Pneumonia Primary Atypical Hospitalization 4/2/2011 72 Male 168 lb 6/29/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Pneumonia Hospitalization 6/18/2011 70 Female 8/9/2011 Physician Germany
Primary
Concomitant
Haematuria Other Serious 1/1/2011 21 Female 119 lb 9/23/2011 Pharmacist Brazil
Primary
Concomitant
Methylobacterium Infection Other Serious 5/22/2011 8 Female 49 lb 9/30/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Periorbital Oedema Life Threatening 1/27/2011 6 Female 40 lb 10/3/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Deep Vein Thrombosis Death 12/7/2010 6 Female 40 lb 10/4/2011 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Pulmonary Hypertension Other Serious 1/1/2011 8 Female 49 lb 10/6/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Methylobacterium Infection Other Serious 8 Female 49 lb 10/6/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Febrile Neutropenia Life Threatening 6 Female 40 lb 10/6/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 2/9/2009 67 Male 10/12/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Hypercalcaemia Hospitalization 12/3/2010 60 Male 143 lb 10/19/2011 Other Health Professional Germany
Primary
Concomitant
Pulmonary Hypertension Other Serious 1/1/2011 8 Female 49 lb 10/21/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Epistaxis Hospitalization 10/1/2011 32 Female 159 lb 11/11/2011 Pharmacist Brazil
Primary
Concomitant
Clostridium Difficile Colitis Hospitalization 10/10/2011 11/14/2011 Physician Australia
Primary
Secondary
Concomitant
Dehydration Hospitalization 10/10/2011 11/22/2011 Physician Australia
Primary
Secondary
Concomitant
Hypoxia Other Serious 5/18/2011 50 Female 84 lb 11/23/2011 Physician Japan
Primary
Concomitant
Oral Candidiasis Hospitalization 10/10/2011 12/1/2011 Physician Australia
Primary
Secondary
Concomitant
Fasciitis Life Threatening 8/5/2011 40 Male 161 lb 12/5/2011 Physician Switzerland
Primary
Secondary
Concomitant
Disseminated Intravascular Coagulation Other Serious 12/2/2011 59 Male 146 lb 12/12/2011 Consumer Netherlands
Primary
Secondary
Concomitant
Disseminated Intravascular Coagulation Other Serious 12/2/2011 59 Male 146 lb 12/16/2011 Physician Netherlands
Primary
Secondary
Concomitant
Disseminated Intravascular Coagulation Other Serious 12/2/2011 59 Male 146 lb 12/23/2011 Consumer Netherlands
Primary
Secondary
Concomitant
Liver Disorder Other Serious 1/1/2011 8 Female 49 lb 12/29/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Tumour Lysis Syndrome Hospitalization 12/3/2010 60 Male 143 lb 12/29/2011 Other Health Professional Germany
Primary
Concomitant
Disseminated Intravascular Coagulation Other Serious 12/2/2011 59 Male 146 lb 12/29/2011 Physician Netherlands
Primary
Secondary
Concomitant
Neurogenic Bladder Other Serious 7/1/2006 46 Male 115 lb 12/27/2011 Physician Japan
Primary
Secondary
Concomitant
Disseminated Intravascular Coagulation Other Serious 12/2/2011 59 Male 146 lb 1/5/2012 Consumer Netherlands
Primary
Secondary
Concomitant
Enterocolitis Death 1/1/2012 56 Male 157 lb 1/11/2012 United Kingdom
Primary
Secondary
Concomitant
Acute Myeloid Leukaemia Death 3/1/2009 78 Female 2/7/2012 Physician Germany
Primary
Concomitant
Infection Hospitalization 10/10/2011 2/9/2012 Physician Australia
Primary
Secondary
Concomitant
Disseminated Intravascular Coagulation Other Serious 12/2/2011 59 Male 146 lb 3/2/2012 Physician Netherlands
Primary
Secondary
Concomitant
Acute Coronary Syndrome Death 4/4/2012 China
Primary
Concomitant
Bronchitis Hospitalization 4/4/2011 55 Male 212 lb 4/5/2012 Physician Germany
Primary
Secondary
Concomitant
Drug Interaction Other Serious 9/18/2011 48 Male 198 lb 4/18/2012 Physician Spain
Primary
Secondary
Bronchitis Hospitalization 4/4/2011 55 Male 212 lb 4/19/2012 Physician Germany
Primary
Secondary
Concomitant
Hepatitis Acute Hospitalization 12/4/2007 84 Male 4/24/2012 Other Health Professional Germany
Primary
Secondary
Concomitant
Hepatitis Acute Other Serious 12/4/2007 84 Male 163 lb 4/26/2012 Physician Germany
Primary
Secondary
Concomitant
Bronchitis Hospitalization 4/4/2011 55 Male 212 lb 5/30/2012 Physician Germany
Primary
Secondary
Concomitant
Sepsis Life Threatening 2/9/2009 67 Male 172 lb 7/12/2012 Other Health Professional Germany
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 8/10/2011 20 Male 157 lb 8/8/2012 Greece
Primary
Concomitant
Interacting
Base Excess Decreased Other Serious 4/25/2012 33 Male 205 lb 7/31/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 4/14/2011 8/16/2012 Other Health Professional Germany
Primary
Concomitant
Venoocclusive Disease Death 8 Female 49 lb 6/27/2013 Other Health Professional Gb
Primary
Secondary
Concomitant
Thrombotic Thrombocytopenic Purpura Hospitalization 6/3/2012 79 Male 161 lb 3/5/2013 Physician De
Primary
Concomitant
Renal Failure Other Serious 4/2/2011 10/9/2012 Physician De
Primary
Concomitant
Vomiting Hospitalization 9/21/2012 73 Male 181 lb 10/31/2012 Physician De
Primary
Secondary
Concomitant
Venoocclusive Disease Other Serious 5/22/2011 8 Female 49 lb 10/10/2012 Us
Primary
Secondary
Concomitant
Vomiting Hospitalization 9/21/2012 72 Male 181 lb 11/9/2012 Physician De
Primary
Secondary
Concomitant
Vomiting Hospitalization 9/21/2012 72 Male 181 lb 11/8/2012 Physician De
Primary
Secondary
Concomitant
Bronchitis Hospitalization 10/11/2012 Male 1/21/2013 Physician De
Primary
Secondary
Concomitant
Platelet Count Increased Other Serious 9/10/2011 46 Female 3/7/2013 Other Health Professional Gb
Primary
Secondary
Concomitant
Circulatory Collapse Hospitalization 2/18/2013 71 Female 3/25/2013 Other Health Professional De
Primary
Secondary
Concomitant
Circulatory Collapse Hospitalization 2/18/2013 71 Female 4/23/2013 Physician De
Primary
Secondary
Concomitant
Platelet Count Increased Other Serious 9/10/2011 46 Female 4/10/2013 Physician Gb
Primary
Secondary
Concomitant
Myositis Other Serious 9/18/2011 48 Male 198 lb 11/2/2012 Physician Es
Primary
Secondary
Presyncope Hospitalization 6/20/2013 Male 7/16/2013 Physician De
Primary
Secondary
Concomitant
Seroma Hospitalization 8/6/2013 Male 9/12/2013 Physician De
Primary
Secondary
Concomitant

Drug Data