Allopurinol combined with Ambisome

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Electrolyte Imbalance Other Serious 1/15/2006 Male 2/6/2006 Physician United States
Primary
Secondary
Concomitant
Herpes Simplex Serology Positive Other Serious 6/10/2005 26 Female 182 lb 2/10/2006 United States
Primary
Secondary
Concomitant
Herpes Simplex Other Serious 6/10/2005 26 Female 182 lb 2/14/2006 United States
Primary
Secondary
Concomitant
Electrocardiogram Qt Corrected Interval Prolonged Other Serious 1/15/2006 51 Male 3/10/2006 Physician United States
Primary
Secondary
Concomitant
Herpes Simplex Other Serious 6/10/2005 26 Female 182 lb 4/19/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Herpes Simplex Hospitalization 6/10/2005 26 Female 182 lb 4/19/2006 United States
Primary
Secondary
Concomitant
Neutropenic Infection Hospitalization 5/15/2006 68 Male 148 lb 6/24/2006 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 5/15/2006 68 Male 148 lb 8/12/2006 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 5/1/2006 33 Female 9/1/2006 Physician United States
Primary
Secondary
Concomitant
Pulmonary Oedema Life Threatening 12/7/2004 68 Female 199 lb 9/8/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Pneumonia Hospitalization 5/15/2006 68 Male 148 lb 9/27/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Hepatosplenomegaly Hospitalization 6/26/2006 44 Male 194 lb 10/4/2006
Primary
Secondary
Concomitant
Hepatomegaly Hospitalization 6/26/2006 44 Male 10/19/2006 France
Primary
Secondary
Concomitant
Tongue Disorder Hospitalization 6/26/2006 44 Male 194 lb 10/27/2006 Other Health Professional France
Primary
Secondary
Concomitant
Stem Cell Transplant Life Threatening 1/5/2007 59 Male 1/30/2007 Other Health Professional Ireland
Primary
Secondary
Concomitant
Renal Tubular Acidosis Life Threatening 1/5/2007 59 Male 3/13/2007 Other Health Professional Ireland
Primary
Secondary
Concomitant
Tachycardia Hospitalization 2/7/2007 40 Male 3/27/2007 Other Health Professional United States
Primary
Concomitant
Tachycardia Hospitalization 2/7/2007 40 Male 4/5/2007 Physician United States
Primary
Concomitant
Virus Urine Test Positive Hospitalization 1/31/2007 40 Male 223 lb 4/30/2007 Physician United States
Primary
Secondary
Concomitant
Lung Infiltration Death 6/28/2007 33 Male 8/3/2007 Other Health Professional Japan
Primary
Secondary
Concomitant
Rash Generalised Life Threatening 9/18/2007 55 Male 10/1/2007 Other Health Professional Italy
Primary
Concomitant
Renal Tubular Acidosis Life Threatening 1/5/2007 Male 10/15/2007 Physician Ireland
Primary
Secondary
Concomitant
Rash Life Threatening 9/18/2007 55 Male 10/17/2007 Other Health Professional Italy
Primary
Concomitant
Renal Tubular Acidosis Life Threatening 1/5/2007 Male 10/26/2007 Physician Ireland
Primary
Secondary
Concomitant
Sepsis Other Serious 7/16/2007 52 Male 10/31/2007 Other Health Professional Japan
Primary
Secondary
Concomitant
Weight Increased Hospitalization 10/15/2007 56 Male 11/15/2007 Physician Germany
Primary
Secondary
Concomitant
Weight Increased Other Serious 10/15/2007 56 Male 11/17/2007 Physician Germany
Primary
Secondary
Concomitant
Weight Increased Other Serious 10/15/2007 56 Male 11/21/2007 Physician Germany
Primary
Secondary
Concomitant
Weight Increased Other Serious 10/15/2007 56 Male 11/22/2007 Physician Germany
Primary
Secondary
Concomitant
Weight Increased Other Serious 10/15/2007 56 Male 11/24/2007 Physician Germany
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Life Threatening 10/14/2007 43 Female 249 lb 11/19/2007 Other Health Professional Italy
Primary
Concomitant
Weight Increased Other Serious 10/15/2007 56 Male 11/29/2007 Physician Germany
Primary
Secondary
Concomitant
Serratia Infection Life Threatening 10/14/2007 43 Female 249 lb 12/5/2007 Other Health Professional Italy
Primary
Concomitant
Ventricular Fibrillation Other Serious 10/14/2007 43 Female 249 lb 12/7/2007 Other Health Professional Italy
Primary
Concomitant
Vomiting Life Threatening 10/28/2007 14 Female 57 lb 12/24/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Sepsis Death 1/30/2008 75 Male 4/17/2008 Physician Greece
Primary
Concomitant
Epstein-barr Virus Infection Life Threatening 3/27/2008 53 Female 121 lb 5/8/2008 Other Health Professional Italy
Primary
Concomitant
Death Death 4/26/2008 56 Male 208 lb 5/19/2008 Other Health Professional United Kingdom
Primary
Concomitant
Death Death 56 Male 208 lb 5/20/2008 United Kingdom
Primary
Concomitant
Sepsis Other Serious 12/20/2007 51 Female 5/28/2008 Physician United States
Primary
Concomitant
Nephropathy Toxic Hospitalization 12/7/2007 58 Male 178 lb 6/22/2008 Pharmacist United States
Primary
Secondary
Concomitant
Nephropathy Toxic Hospitalization 12/4/2007 69 Male 183 lb 6/22/2008 Pharmacist United States
Primary
Secondary
Concomitant
Nephropathy Toxic Hospitalization 12/5/2007 43 Male 197 lb 6/22/2008 Pharmacist United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Death 1/30/2008 75 Male 7/14/2008 Physician Greece
Primary
Concomitant
Liver Function Test Abnormal Hospitalization 39 220 lb 8/15/2008 United Kingdom
Primary
Secondary
Concomitant
Subdural Haematoma Other Serious 12/31/2008 Male 2/6/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Syncope Other Serious 12/31/2008 Male 2/20/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Syncope Other Serious 12/31/2008 Male 2/20/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Paraesthesia Hospitalization 5/1/2008 69 Male 6/18/2009 Other Health Professional United Kingdom
Primary
Concomitant
Tongue Haemorrhage Other Serious 7/1/2008 Male 8/7/2009 Physician Germany
Primary
Secondary
Concomitant
Weight Increased Other Serious 10/15/2007 Male 9/11/2009 Physician Germany
Primary
Secondary
Concomitant
Small Intestinal Obstruction Hospitalization 7/24/2009 60 Male 9/24/2009 Physician United States
Primary
Secondary
Concomitant
Refusal Of Treatment By Patient Other Serious 11/27/2007 49 Male 189 lb 10/5/2009 Physician United States
Primary
Secondary
Concomitant
Ventricular Tachycardia Life Threatening 6/25/2009 72 Male 133 lb 10/8/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Unresponsive To Stimuli Hospitalization 7/24/2009 60 Male 223 lb 10/21/2009 Physician United States
Primary
Secondary
Concomitant
Unresponsive To Stimuli Other Serious 7/24/2009 60 Male 223 lb 11/5/2009 Physician United States
Primary
Secondary
Concomitant
Sepsis Other Serious 7/8/2007 52 Male 11/17/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Ventricular Tachycardia Other Serious 6/25/2009 72 Male 132 lb 11/18/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Tachycardia Other Serious 10/23/2009 42 Female 271 lb 11/20/2009 Other Health Professional Australia
Primary
Concomitant
Hepatotoxicity Death 9/21/2009 33 Female 1/21/2010 Pharmacist Spain
Primary
Concomitant
Ventricular Tachycardia Other Serious 6/25/2009 72 Male 132 lb 2/5/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Septic Shock Hospitalization 3/1/2009 58 Male 3/8/2010 Physician Japan
Primary
Secondary
Concomitant
Septic Shock Hospitalization 3/1/2009 58 Male 3/10/2010 Physician Japan
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 12/29/2009 75 Male 4/12/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 12/29/2009 75 Male 5/4/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Transplant Failure Other Serious 1/26/2009 58 Male 157 lb 5/18/2010 Physician Italy
Primary
Concomitant
Thrombocytopenia Other Serious 12/29/2009 75 Male 7/7/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Scedosporium Infection Other Serious 11/16/2009 35 Male 132 lb 7/7/2010 Physician Japan
Primary
Secondary
Concomitant
Scedosporium Infection Other Serious 4/25/2009 34 Male 132 lb 7/20/2010 Physician Japan
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 12/29/2009 75 Male 7/29/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Staphylococcal Infection Other Serious 8/26/2010 63 Female 9/14/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Gastrointestinal Necrosis Death 10/20/2010 24 Female 128 lb 1/27/2011 Physician Netherlands
Primary
Secondary
Concomitant
Staphylococcal Infection Other Serious 8/26/2010 63 Female 1/28/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Disseminated Intravascular Coagulation Life Threatening 4/25/2009 34 Male 132 lb 1/18/2011 Physician Japan
Primary
Secondary
Concomitant
Renal Failure Other Serious 10/20/2010 24 Female 128 lb 2/9/2011 Physician Netherlands
Primary
Secondary
Concomitant
Bone Marrow Failure Other Serious 8/26/2010 63 Female 2/10/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Pyrexia Life Threatening 2/11/2011 1 Female 3/7/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Hypertonia Disability 1/21/2011 0 Male 11 lb 3/15/2011 Other Health Professional United Kingdom
Primary
Concomitant
Multi-organ Failure Hospitalization 10/20/2010 24 Female 128 lb 3/21/2011 Physician Netherlands
Primary
Secondary
Concomitant
Hypertonia Disability 1/21/2011 0 Male 11 lb 3/11/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Convulsion Disability 1/21/2011 0 Male 3/15/2011 Physician Denmark
Primary
Secondary
Concomitant
Chloroma Life Threatening 2/11/2011 1 Female 3/25/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Hyperbilirubinaemia Hospitalization 2/24/2011 54 Female 153 lb 3/30/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Pyrexia Other Serious 4/25/2009 34 Male 132 lb 4/26/2011 Physician Japan
Primary
Secondary
Concomitant
Hydrocephalus Death 2/11/2011 1 Female 22 lb 5/20/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Renal Disorder Life Threatening 7/25/2010 60 Female 93 lb 5/24/2011 Physician Japan
Primary
Secondary
Concomitant
Death Life Threatening 4/2/2011 6/10/2011 Physician Japan
Primary
Concomitant
Cardiac Failure Life Threatening 4/2/2011 7/1/2011 Physician Japan
Primary
Concomitant
Blood Bilirubin Increased Other Serious 1/18/2011 68 Female 7/13/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Blood Bilirubin Increased Other Serious 1/18/2011 68 Female 7/18/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Face Oedema Other Serious 6/27/2011 31 Male 146 lb 7/18/2011 Physician Spain
Primary
Concomitant
Respiratory Tract Infection Fungal Other Serious 3/31/2011 7 Male 55 lb 7/25/2011 Consumer United Kingdom
Primary
Secondary
Concomitant
Pneumonia Death 50 Male 8/2/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Neutropenic Sepsis Hospitalization 7/13/2009 77 Male 8/5/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Skin Hyperpigmentation Death 6/20/2011 11 Female 77 lb 8/12/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Epstein-barr Virus Infection Life Threatening 10/23/2009 42 Female 216 lb 9/15/2011 Other Health Professional Australia
Primary
Concomitant
Alanine Aminotransferase Increased Other Serious 9/10/2011 46 Female 10/12/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Platelet Count Increased Other Serious 9/10/2011 46 Female 10/14/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Headache Other Serious 6/20/2011 11 Female 77 lb 10/28/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Platelet Count Decreased Other Serious 9/12/2011 46 Female 10/31/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Myelodysplastic Syndrome Other Serious 8/7/2010 64 Male 143 lb 11/4/2011 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 8/7/2010 64 Male 143 lb 11/4/2011 Physician Japan
Primary
Secondary
Concomitant
Acute Respiratory Distress Syndrome Death 5/20/2011 66 Male 130 lb 11/7/2011 Physician United States
Primary
Concomitant
Platelet Count Increased Other Serious 9/10/2011 46 Female 11/11/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Platelet Count Increased Death 8/7/2010 64 Male 143 lb 12/31/2011 Physician Japan
Primary
Secondary
Concomitant
Renal Failure Life Threatening 12/20/2011 70 Male 192 lb 1/5/2012 Physician Germany
Primary
Secondary
Concomitant
Encephalopathy Life Threatening 12/20/2011 70 Male 192 lb 1/10/2012 Consumer Germany
Primary
Secondary
Concomitant
Multi-organ Failure Life Threatening 12/20/2011 70 Male 192 lb 2/6/2012 Physician Germany
Primary
Secondary
Concomitant
Sepsis Life Threatening 12/20/2011 70 Male 192 lb 2/13/2012 Physician Germany
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 2/7/2012 58 Female 148 lb 2/23/2012 Physician Italy
Primary
Secondary
Concomitant
Anaphylactic Reaction Other Serious 1/4/2012 3 Male 42 lb 2/27/2012 Pharmacist United Kingdom
Primary
Concomitant
Hepatic Failure Hospitalization 2/5/2012 58 Female 148 lb 3/5/2012 Physician Italy
Primary
Secondary
Concomitant
Petechiae Hospitalization 5/1/2010 69 Female 3/6/2012 Consumer Germany
Primary
Secondary
Concomitant
Petechiae Death 5/1/2010 69 Female 3/16/2012 Other Health Professional Spain
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 2/5/2012 58 Female 148 lb 3/20/2012 Physician Italy
Primary
Secondary
Concomitant
Myositis Other Serious 9/18/2011 48 Male 198 lb 4/6/2012 Pharmacist Spain
Primary
Interacting
Myositis Other Serious 9/18/2011 48 Male 198 lb 4/6/2012 Pharmacist Spain
Primary
Interacting
Myositis Other Serious 9/18/2011 48 Male 198 lb 4/6/2012 Pharmacist Spain
Primary
Secondary
Myositis Other Serious 9/18/2011 48 Male 198 lb 4/9/2012 Other Health Professional Spain
Primary
Secondary
Myositis Other Serious 9/18/2011 48 Male 198 lb 4/11/2012 Pharmacist Spain
Primary
Secondary
Drug Interaction Other Serious 9/18/2011 48 Male 198 lb 4/12/2012 Physician Spain
Primary
Interacting
Drug Interaction Other Serious 9/18/2011 48 Male 198 lb 4/12/2012 Other Health Professional Spain
Primary
Interacting
Myositis Other Serious 48 Male 198 lb 4/12/2012 Pharmacist Spain
Primary
Secondary
Drug Interaction Other Serious 9/18/2011 48 Male 198 lb 4/17/2012 Consumer United States
Primary
Interacting
Neoplasm Malignant Hospitalization 8/7/2010 64 Male 143 lb 4/17/2012 Physician Japan
Primary
Secondary
Concomitant
Myositis Other Serious 9/18/2011 48 Male 198 lb 4/18/2012 Consumer Spain
Primary
Secondary
Drug Interaction Other Serious 9/18/2011 48 Male 198 lb 4/23/2012 Japan
Primary
Interacting
Drug Interaction Other Serious 9/18/2011 48 Male 198 lb 4/25/2012 Pharmacist Spain
Primary
Secondary
Interacting
Febrile Neutropenia Death 1/5/2012 71 Male 99 lb 8/14/2012 Physician Japan
Primary
Secondary
Concomitant
Platelet Count Increased Other Serious 9/10/2011 46 Female 4/3/2013 Physician Gb
Primary
Secondary
Concomitant
Platelet Count Increased Other Serious 9/10/2011 46 Female 3/22/2013 Physician Gb
Primary
Secondary
Concomitant
Platelet Count Increased Other Serious 9/10/2011 46 Female 5/2/2013 Other Health Professional Gb
Primary
Secondary
Concomitant
Treatment Failure Hospitalization 4/25/2012 33 Male 205 lb 9/21/2012 Other Health Professional Us
Primary
Secondary
Concomitant
Renal Failure Acute Life Threatening 4/25/2012 33 Male 205 lb 8/29/2012 Other Health Professional Us
Primary
Secondary
Concomitant
Sepsis Hospitalization 4/4/2012 75 Male 123 lb 10/15/2012 Physician Jp
Primary
Concomitant
Skin Reaction Other Serious Male 11/8/2012 Physician Ch
Primary
Concomitant
Respiratory Failure Disability 7/13/2012 59 Female 12/20/2012 Physician Gb
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 7/13/2012 59 Female 220 lb 11/26/2012 Other Health Professional Gb
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 7/13/2012 59 Female 218 lb 12/18/2012 Other Health Professional Gb
Primary
Secondary
Concomitant
Respiratory Failure Disability 7/13/2012 59 Female 218 lb 12/27/2012 Other Health Professional Gb
Primary
Secondary
Concomitant
Respiratory Tract Infection Fungal Disability 7/13/2012 59 Female 220 lb 1/2/2013 Physician Gb
Primary
Secondary
Concomitant
Platelet Count Increased Other Serious 9/10/2011 46 Female 3/27/2013 Other Health Professional Gb
Primary
Secondary
Concomitant
Platelet Count Increased Other Serious 9/10/2011 46 Female 4/6/2013 Physician Gb
Primary
Secondary
Concomitant
Platelet Count Increased Other Serious 9/10/2011 46 Female 4/5/2013 Other Health Professional Gb
Primary
Secondary
Concomitant
Platelet Count Increased Other Serious 9/10/2011 46 Female 3/27/2013 Physician Gb
Primary
Secondary
Concomitant
Platelet Count Increased Other Serious 9/10/2011 46 Female 3/20/2013 Other Health Professional Gb
Primary
Secondary
Concomitant
Platelet Count Increased Other Serious 9/10/2011 46 Female 4/3/2013 Consumer Gb
Primary
Secondary
Concomitant
Neutropenia Other Serious 3/23/2012 59 Female 218 lb 6/12/2013 Other Health Professional Gb
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 7/13/2012 59 Female 220 lb 6/14/2013 Other Health Professional Gb
Primary
Secondary
Concomitant
Tumour Lysis Syndrome Death 5/2013 16 Female 6/14/2013 Consumer Nl
Primary
Secondary
Concomitant

Drug Data