Alkeran combined with Etoposide

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Renal Failure Acute Death 2/20/2006 3 Male 26 lb 5/31/2006 Physician Japan
Primary
Secondary
Concomitant
Respiratory Disorder Death 2/26/2004 6 Male 6/16/2006 Consumer Japan
Primary
Secondary
Urine Output Decreased Other Serious 2/20/2006 3 Male 26 lb 7/5/2006 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Death 5/26/2006 74 Male 225 lb 9/20/2006 Other Health Professional Japan
Primary
Secondary
Stem Cell Transplant Death Unknown 9/29/2006 France
Primary
Secondary
Concomitant
Neurotoxicity Other Serious Unknown 9/29/2006 France
Primary
Secondary
Concomitant
Capillary Leak Syndrome Death 11/11/2005 10 Female 12/14/2006 Physician Japan
Primary
Concomitant
Renal Failure Acute Hospitalization 2/1/2006 59 Female 130 lb 1/18/2007 Consumer France
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 2/1/2006 59 Female 130 lb 1/26/2007 Consumer France
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Death 2/13/2007 Germany
Primary
Secondary
Concomitant
Arrhythmia Death Unknown 2/13/2007 Germany
Primary
Secondary
Concomitant
Gastrointestinal Inflammation Other Serious 51 Male 2/13/2007 United Kingdom
Primary
Secondary
Septic Shock Death Unknown 3/19/2007 Italy
Primary
Secondary
Vomiting Life Threatening 5/4/2006 42 Male 229 lb 4/10/2007 Other Health Professional Canada
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious Unknown 4/16/2007 Germany
Primary
Secondary
Vomiting Life Threatening 5/4/2006 42 Male 229 lb 5/1/2007 Other Health Professional Canada
Primary
Secondary
Concomitant
Pancytopenia Hospitalization 1/1/2007 57 Male 9/13/2007 Consumer France
Primary
Secondary
Concomitant
Pancytopenia Hospitalization Male 9/19/2007 Consumer France
Primary
Secondary
Concomitant
Febrile Bone Marrow Aplasia Hospitalization 12/13/2006 51 Male 161 lb 10/4/2007 Physician France
Primary
Secondary
Pancytopenia Hospitalization 1/1/2007 57 Male 10/31/2007 Consumer France
Primary
Secondary
Concomitant
Pancytopenia Hospitalization Male 11/2/2007 Consumer France
Primary
Secondary
Concomitant
Acute Myeloid Leukaemia Hospitalization 9/1/2007 69 Male 11/6/2007 Consumer United States
Primary
Secondary
Acute Myeloid Leukaemia Hospitalization 9/1/2007 Male 11/28/2007 Other Health Professional United Kingdom
Primary
Secondary
Neoplasm Hospitalization 5/23/2007 56 Male 115 lb 1/8/2008 Physician Japan
Primary
Concomitant
Autosomal Chromosome Anomaly Hospitalization 5/23/2007 56 Male 115 lb 2/27/2008 Physician Japan
Primary
Secondary
Concomitant
Thrombotic Microangiopathy Other Serious 1/1/2007 25 Female 3/14/2008 Physician Japan
Primary
Concomitant
Thrombotic Microangiopathy Other Serious 5/1/2007 40 Male 3/14/2008 Physician Japan
Primary
Concomitant
Skin Hyperpigmentation Hospitalization 3/6/2008 1 Female 36 lb 4/18/2008 Consumer France
Primary
Secondary
Acute Myeloid Leukaemia Hospitalization 9/1/2007 69 Male 4/24/2008 Consumer France
Primary
Secondary
Diffuse Large B-cell Lymphoma Death 11/1/2006 59 Male 5/1/2008 Physician Japan
Primary
Secondary
Concomitant
Toxic Skin Eruption Hospitalization 3/6/2008 1 Female 36 lb 5/16/2008 Consumer France
Primary
Secondary
Febrile Bone Marrow Aplasia Hospitalization 12/13/2006 51 Male 161 lb 5/22/2008 Physician France
Primary
Secondary
Troponin Increased Other Serious 7/1/2008 62 Female 8/19/2008 Other Health Professional France
Primary
Concomitant
Stem Cell Transplant Other Serious 2/1/2007 57 Male 8/29/2008 Other Health Professional France
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 7/1/2008 62 Female 9/25/2008 Other Health Professional France
Primary
Concomitant
Transplant Death 11/7/2008 Consumer Japan
Primary
Secondary
Venoocclusive Liver Disease Death 2 Male 11/10/2008 Consumer Japan
Primary
Secondary
Venoocclusive Liver Disease Death 1 Female 11/10/2008 Consumer Japan
Primary
Secondary
Diffuse Large B-cell Lymphoma Death 11/1/2006 59 Male 11/19/2008 Physician Japan
Primary
Secondary
Concomitant
Sepsis Death 11/20/2008 Physician Japan
Primary
Secondary
Venoocclusive Liver Disease Death 2 Male 11/21/2008 Physician Japan
Primary
Secondary
Venoocclusive Liver Disease Death 1 Female 11/21/2008 Physician Japan
Primary
Secondary
Sepsis Death 7/1/2006 59 Male 12/23/2008 Physician Japan
Primary
Secondary
Concomitant
Hypertension Other Serious 1/17/2008 9 Male 88 lb 12/26/2008 Physician Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Other Serious 3 Male 1/26/2009 Other Health Professional Japan
Primary
Secondary
Tubulointerstitial Nephritis Hospitalization 2/26/2008 4 Female 36 lb 1/30/2009 Consumer France
Primary
Secondary
Interstitial Lung Disease Death 3 Male 2/6/2009 Consumer Japan
Primary
Secondary
Concomitant
Pericardial Effusion Other Serious 3 Female 2/12/2009 Physician Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Death 3 Male 2/16/2009 Consumer Japan
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 3 Male 2/17/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 3 Male 2/17/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Sepsis Death 7/1/2006 59 Male 2/26/2009 Physician Japan
Primary
Secondary
Concomitant
Gastrointestinal Disorder Other Serious 6/1/2008 34 Male 3/9/2009 Physician Japan
Primary
Concomitant
Tubulointerstitial Nephritis Hospitalization 2/26/2008 4 Female 36 lb 3/13/2009 Consumer France
Primary
Secondary
Toxic Skin Eruption Hospitalization 3/6/2008 4 Female 3/11/2009 France
Primary
Secondary
Mouth Ulceration Hospitalization 5/7/2009 Female 6/8/2009 Physician France
Primary
Secondary
Stomatitis Hospitalization 5/7/2009 Female 6/12/2009 Consumer France
Primary
Secondary
Concomitant
Pyrexia Hospitalization 4/26/2009 Male 128 lb 6/22/2009 Consumer France
Primary
Secondary
Urticaria Other Serious 12/9/2008 7 Female 7/13/2009 Other Health Professional Japan
Primary
Concomitant
Pain In Extremity Other Serious 11 Male 7/23/2009 Consumer Japan
Primary
Secondary
Troponin Increased Other Serious 7/1/2008 62 Female 8/5/2009 Other Health Professional France
Primary
Concomitant
Pancytopenia Death 6/1/2009 64 Female 8/20/2009 Physician France
Primary
Secondary
Concomitant
Toxic Skin Eruption Hospitalization 1/1/2009 Female 168 lb 8/21/2009 Consumer France
Primary
Secondary
Concomitant
Pancytopenia Hospitalization 6/1/2009 64 Female 8/25/2009 Other Health Professional France
Primary
Secondary
Concomitant
Pyrexia Hospitalization 6/1/2009 64 Female 8/28/2009 Other Health Professional France
Primary
Secondary
Concomitant
Pancytopenia Death 6/1/2009 64 Female 9/1/2009 Physician France
Primary
Secondary
Concomitant
Toxic Skin Eruption Hospitalization 1/1/2009 Female 168 lb 9/1/2009 Consumer France
Primary
Secondary
Concomitant
Urticaria Other Serious 12/9/2008 7 Female 10/15/2009 Physician Japan
Primary
Concomitant
Myelodysplastic Syndrome Other Serious 10/30/2009 Consumer Japan
Primary
Concomitant
Otitis Externa Hospitalization 10/10/2009 Male 141 lb 12/2/2009 Consumer United Kingdom
Primary
Concomitant
Thrombotic Microangiopathy Other Serious 2/11/2009 24 Female 12/4/2009 Japan
Primary
Secondary
Concomitant
Staphylococcal Sepsis Hospitalization 10/14/2009 Male 2/4/2010 Consumer Italy
Primary
Secondary
Concomitant
Neutrophil Count Decreased Other Serious 78 Male 2/24/2010 Consumer Japan
Primary
Concomitant
Staphylococcal Sepsis Hospitalization Male 3/23/2010 Consumer Italy
Primary
Secondary
Concomitant
Pulmonary Fibrosis Hospitalization 1/1/2007 36 Male 4/27/2010 Physician France
Primary
Secondary
Pulmonary Fibrosis Hospitalization 11/1/2007 36 Male 5/3/2010 Other Health Professional France
Primary
Secondary
Pulmonary Fibrosis Hospitalization 11/1/2007 36 Male 5/10/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Pulmonary Fibrosis Hospitalization 11/1/2007 36 Male 6/3/2010 Other Health Professional Japan
Primary
Secondary
Respiratory Failure Hospitalization 1/1/2007 36 Male 7/12/2010 Physician France
Primary
Secondary
Pulmonary Fibrosis Hospitalization 11/1/2007 36 Male 7/15/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 11/1/2007 36 Male 7/16/2010 Consumer France
Primary
Secondary
Weight Increased Other Serious 1/1/1995 57 Male 7/19/2010 United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 9/1/2006 22 Male 170 lb 7/21/2010 United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/1995 57 Male 8/6/2010 United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 9/1/2006 22 Male 170 lb 9/2/2010 United States
Primary
Secondary
Concomitant
Stomatitis Other Serious 50 Male 9/14/2010 Physician Japan
Primary
Concomitant
Weight Increased Other Serious 1/1/1995 57 Male 9/17/2010 United States
Primary
Secondary
Concomitant
Stomatitis Other Serious 8/12/2009 50 Male 10/7/2010 Pharmacist Japan
Primary
Secondary
Concomitant
Stomatitis Other Serious 8/12/2009 50 Male 10/20/2010 Pharmacist Japan
Primary
Secondary
Concomitant
Peripheral Sensory Neuropathy Hospitalization 8/30/2010 54 Female 119 lb 11/11/2010 Physician Japan
Primary
Secondary
Concomitant
Hepatic Function Abnormal Other Serious 7/21/2009 34 Male 174 lb 12/22/2010 Physician Japan
Primary
Secondary
Concomitant
Hepatic Function Abnormal Other Serious 7/21/2009 34 Male 174 lb 12/29/2010 Physician Japan
Primary
Secondary
Concomitant
Squamous Cell Carcinoma Other Serious 21 Male 12/29/2010 Physician Japan
Primary
Concomitant
Bone Sarcoma Other Serious 11 Male 1/3/2011 Physician Japan
Primary
Secondary
Peripheral Sensory Neuropathy Disability 8/30/2010 54 Female 119 lb 1/3/2011 Physician Japan
Primary
Concomitant
Cytomegalovirus Chorioretinitis Hospitalization 5/25/2010 67 Male 168 lb 1/19/2011 Physician Japan
Primary
Secondary
Concomitant
Sepsis Death 4/13/2009 66 Female 134 lb 1/31/2011 Physician Japan
Primary
Concomitant
Sepsis Death 4/13/2009 66 Female 134 lb 2/24/2011 Physician Japan
Primary
Secondary
Concomitant
Septic Shock Death 10/12/2005 35 Male 207 lb 3/10/2011 Physician Japan
Primary
Concomitant
Febrile Neutropenia Hospitalization 9/18/2010 58 Female 110 lb 3/17/2011 Physician Japan
Primary
Secondary
Concomitant
Hypomagnesaemia Other Serious 1/1/1995 57 Male 3/28/2011 Lawyer United States
Primary
Secondary
Concomitant
Squamous Cell Carcinoma Death 9/1/2009 20 Male 4/8/2011 Physician Japan
Primary
Concomitant
Mucous Membrane Disorder Disability 8/1/2009 20 Male 110 lb 4/13/2011 Physician Japan
Primary
Secondary
Concomitant
Abdominal Pain Disability 10/4/2010 20 Female 106 lb 4/13/2011 Physician Japan
Primary
Secondary
Concomitant
Febrile Neutropenia Other Serious 9/4/2010 Male 33 lb 4/20/2011 Physician Japan
Primary
Secondary
Concomitant
Febrile Neutropenia Other Serious 11/27/2010 Male 32 lb 4/20/2011 Pharmacist Japan
Primary
Secondary
Concomitant
Pneumonia Cytomegaloviral Death 6/9/2009 10 Male 63 lb 5/5/2011 Physician Japan
Primary
Secondary
Concomitant
Systemic Candida Death 8/7/2009 12 Male 95 lb 5/6/2011 Physician Japan
Primary
Secondary
Concomitant
Febrile Neutropenia Disability 5/1/2008 3 Female 27 lb 5/6/2011 Physician Japan
Primary
Secondary
Concomitant
Myelodysplastic Syndrome Other Serious 3/28/2007 55 Female 5/11/2011 Other Health Professional United States
Primary
Secondary
Renal Failure Disability 5/25/2008 4 Male 37 lb 5/19/2011 Physician Japan
Primary
Secondary
Concomitant
Sepsis Hospitalization 3/12/2010 58 Female 108 lb 5/19/2011 Physician Japan
Primary
Secondary
Concomitant
Renal Disorder Life Threatening 7/25/2010 60 Female 93 lb 5/24/2011 Physician Japan
Primary
Secondary
Concomitant
Sepsis Death 12/15/2007 Female 121 lb 5/24/2011 Physician Japan
Primary
Secondary
Concomitant
Pyrexia Hospitalization 2/28/2004 64 Male 157 lb 6/8/2011 Physician Japan
Primary
Concomitant
Pneumonia Life Threatening 10/15/2007 40 Female 148 lb 6/22/2011 Physician Japan
Primary
Secondary
Concomitant
Septic Shock Death 10/12/2005 35 Male 207 lb 6/30/2011 Physician Japan
Primary
Secondary
Concomitant
Acute Respiratory Distress Syndrome Life Threatening 11/11/2007 12 Female 80 lb 7/5/2011 Physician Japan
Primary
Secondary
Concomitant
Mucous Membrane Disorder Disability 8/1/2009 20 Male 110 lb 7/5/2011 Physician Japan
Primary
Secondary
Concomitant
Viral Infection Life Threatening 10/8/2007 57 Male 205 lb 7/6/2011 Physician Japan
Primary
Concomitant
Enterocolitis Haemorrhagic Death 6/10/2003 29 Male 168 lb 7/13/2011 Physician Japan
Primary
Secondary
Concomitant
Systemic Candida Death 8/7/2009 12 Male 95 lb 7/14/2011 Physician Japan
Primary
Secondary
Concomitant
Pneumonia Cytomegaloviral Death 6/9/2009 10 Male 64 lb 7/15/2011 Physician Japan
Primary
Secondary
Concomitant
Antithrombin Iii Decreased Hospitalization 5/1/2008 3 Female 27 lb 8/1/2011 Physician Japan
Primary
Secondary
Concomitant
Hyperamylasaemia Disability 7/12/2008 8 Male 44 lb 8/1/2011 Physician Japan
Primary
Secondary
Concomitant
Acute Myeloid Leukaemia Life Threatening 1/1/2011 57 Male 8/5/2011 Consumer France
Primary
Secondary
Myelofibrosis Other Serious 1/1/2011 57 Male 8/8/2011 Other Health Professional France
Primary
Secondary
Progressive Multifocal Leukoencephalopathy Life Threatening 5/10/2011 58 Female 8/9/2011 Physician France
Primary
Secondary
Refractory Anaemia With An Excess Of Blasts Life Threatening 1/1/2011 57 Male 8/11/2011 Other Health Professional United Kingdom
Primary
Secondary
Movement Disorder Life Threatening 5/10/2011 58 Female 8/11/2011 Physician France
Primary
Secondary
Refractory Anaemia With An Excess Of Blasts Life Threatening 1/1/2011 57 Male 8/11/2011 Other Health Professional France
Primary
Secondary
Herpes Zoster Hospitalization 5/12/2010 58 Male 168 lb 8/12/2011 Physician Japan
Primary
Secondary
Concomitant
Refractory Anaemia With An Excess Of Blasts Life Threatening 1/1/2011 57 Male 8/12/2011 Physician France
Primary
Secondary
Acute Myeloid Leukaemia Life Threatening 1/1/2011 57 Male 8/16/2011 Other Health Professional France
Primary
Secondary
Congestive Cardiomyopathy Disability 5/25/2008 4 Male 37 lb 8/26/2011 Physician Japan
Primary
Secondary
Concomitant
Myelofibrosis Life Threatening 1/1/2011 57 Male 9/5/2011 Other Health Professional France
Primary
Secondary
Myelofibrosis Life Threatening 1/1/2011 57 Male 9/7/2011 Physician France
Primary
Secondary
Viral Haemorrhagic Cystitis Other Serious 10/4/2010 68 Female 108 lb 9/7/2011 Physician Japan
Primary
Secondary
Concomitant
Aspartate Aminotransferase Increased Other Serious 12/22/2010 62 Male 161 lb 9/7/2011 Physician Japan
Primary
Secondary
Concomitant
Acute Myeloid Leukaemia Life Threatening 1/1/2011 57 Male 9/7/2011 Consumer United Kingdom
Primary
Secondary
Viral Haemorrhagic Cystitis Other Serious 10/4/2010 68 Female 108 lb 10/10/2011 Physician Japan
Primary
Secondary
Concomitant
Neoplasm Malignant Other Serious 8/1/2011 58 Male 10/24/2011 Other Health Professional France
Primary
Secondary
Myelodysplastic Syndrome Other Serious 8/1/2011 58 Male 10/25/2011 Other Health Professional France
Primary
Secondary
Concomitant
Myeloma Recurrence Other Serious 8/1/2011 58 Male 11/30/2011 Other Health Professional France
Primary
Secondary
Myelodysplastic Syndrome Other Serious 8/1/2011 58 Male 12/5/2011 Other Health Professional France
Primary
Secondary
Concomitant
Ejection Fraction Decreased Life Threatening 1/14/2011 62 Female 12/19/2011 Other Health Professional France
Primary
Secondary
Concomitant
Vomiting Hospitalization 8/4/2011 66 Male 12/23/2011 Consumer France
Primary
Secondary
Concomitant
Vomiting Hospitalization 8/4/2011 66 Male 12/27/2011 Other Health Professional France
Primary
Secondary
Concomitant
Acute Myeloid Leukaemia Other Serious 11/1/2011 67 Male 12/28/2011 Other Health Professional France
Primary
Secondary
Concomitant
Altered State Of Consciousness Death 7/31/2011 63 Female 1/5/2012 Physician France
Primary
Secondary

Drug Data