Alkeran combined with Cyclophosphamide

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Surgical Procedure Repeated Other Serious 64 Female 4/4/2006 Physician Germany
Primary
Concomitant
Weight Increased Hospitalization 11/23/2003 5 Female 4/28/2006 Physician Japan
Primary
Secondary
Concomitant
Respiratory Disorder Death 2/26/2004 6 Male 6/16/2006 Consumer Japan
Primary
Secondary
Mucosal Inflammation Other Serious 9 Female 10/31/2006 Netherlands
Primary
Secondary
Concomitant
Sepsis Death 13 Male 10/31/2006 Netherlands
Primary
Secondary
Concomitant
Venoocclusive Disease Required Intervention 16 Male 10/31/2006 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Skin Odour Abnormal Required Intervention 80 Female 12/18/2006 Italy
Primary
Secondary
Toxic Epidermal Necrolysis Death 2/13/2007 Germany
Primary
Secondary
Concomitant
Arrhythmia Death Unknown 2/13/2007 Germany
Primary
Secondary
Concomitant
Weight Increased Required Intervention 1/7/2007 1 Female 4/23/2007 France
Primary
Secondary
Neurotoxicity Life Threatening 74 Male 165 lb 5/11/2007 France
Primary
Secondary
Neurotoxicity Life Threatening 74 Male 165 lb 5/24/2007 France
Primary
Secondary
Renal Failure Acute Hospitalization 5/7/2007 45 Male 247 lb 6/29/2007 Consumer France
Primary
Concomitant
Febrile Bone Marrow Aplasia Hospitalization 12/13/2006 51 Male 161 lb 10/4/2007 Physician France
Primary
Secondary
Drug Toxicity Death Unknown 10/30/2007 France
Primary
Secondary
Drug Toxicity Death Unknown 10/30/2007 France
Primary
Secondary
Acute Myeloid Leukaemia Hospitalization 9/1/2007 Male 11/28/2007 Other Health Professional United Kingdom
Primary
Secondary
Sepsis Hospitalization 6/17/2003 62 Female 121 lb 12/13/2007 Physician Japan
Primary
Concomitant
Sepsis Hospitalization 6/17/2003 62 Female 121 lb 12/14/2007 Physician Japan
Primary
Concomitant
Hepatic Neoplasm Malignant Hospitalization 9/24/2004 62 Male 1/7/2008 Physician Japan
Primary
Secondary
Hepatic Neoplasm Malignant Hospitalization 9/24/2004 62 Male 2/27/2008 Physician Japan
Primary
Secondary
Febrile Bone Marrow Aplasia Hospitalization 12/13/2006 51 Male 161 lb 5/22/2008 Physician France
Primary
Secondary
Sinusitis Hospitalization 4/1/2008 71 Male 6/11/2008 Consumer France
Primary
Concomitant
Skin Haemorrhage Other Serious 50 Male 7/7/2008 Russian Federation
Primary
Secondary
Penis Carcinoma Death 45 Male 8/27/2008 Portugal
Primary
Secondary
Concomitant
Breast Cancer Female Other Serious 52 Female 8/27/2008 Portugal
Primary
Concomitant
Precancerous Skin Lesion Other Serious 64 Female 8/27/2008 Portugal
Primary
Secondary
Concomitant
Squamous Cell Carcinoma Other Serious 56 Male 8/27/2008 Portugal
Primary
Secondary
Concomitant
Sepsis Death 7/1/2006 59 Male 12/23/2008 Physician Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Other Serious 3 Male 1/26/2009 Other Health Professional Japan
Primary
Secondary
Respiratory Failure Other Serious 3 Male 2/17/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 3 Male 2/17/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Sepsis Death 7/1/2006 59 Male 2/26/2009 Physician Japan
Primary
Secondary
Concomitant
Drug Toxicity Death Unknown 4/1/2009 Italy
Primary
Secondary
Concomitant
Thrombotic Microangiopathy Other Serious 2/11/2009 24 Female 12/4/2009 Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Death 3/18/2009 58 Female 125 lb 12/14/2009 Physician Japan
Primary
Concomitant
Sequestrectomy Other Serious 12/1/2006 Male 12/31/2009 Other Health Professional Italy
Primary
Secondary
Concomitant
Sepsis Life Threatening 3/18/2009 58 Female 125 lb 1/19/2010 Physician Japan
Primary
Concomitant
Sequestrectomy Other Serious 12/1/2006 Male 2/1/2010 Other Health Professional Italy
Primary
Secondary
Concomitant
Walking Aid User Other Serious 8/11/2008 Male 219 lb 3/5/2010 United States
Primary
Secondary
Concomitant
Walking Aid User Other Serious 5/1/2007 Male 219 lb 3/19/2010 United States
Primary
Secondary
Concomitant
Walking Aid User Other Serious 5/1/2007 Male 219 lb 3/31/2010 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 11/1/2001 50 Female 4/7/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Neoplasm Malignant Hospitalization 12/1/2009 14 Female 4/9/2010 Consumer France
Primary
Secondary
Wound Infection Other Serious 5/1/2007 68 Male 219 lb 4/15/2010 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 11/1/2001 50 Female 4/19/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Tumour Necrosis Hospitalization 1/27/2010 14 Female 4/16/2010 Other Health Professional France
Primary
Secondary
Respiratory Failure Hospitalization 1/1/2007 36 Male 7/12/2010 Physician France
Primary
Secondary
Pulmonary Fibrosis Hospitalization 11/1/2007 36 Male 7/15/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 11/1/2007 36 Male 7/16/2010 Consumer France
Primary
Secondary
Weight Increased Other Serious 1/1/1995 57 Male 7/19/2010 United States
Primary
Secondary
Concomitant
Wheezing Other Serious 5/9/1997 37 Female 193 lb 8/4/2010 United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/1995 57 Male 8/6/2010 United States
Primary
Secondary
Concomitant
Myoclonus Other Serious 1/12/2010 62 Male 9/10/2010 Physician Japan
Primary
Concomitant
Myoclonic Epilepsy Other Serious 65 Female 9/10/2010 Physician Japan
Primary
Concomitant
Weight Increased Other Serious 1/1/1995 57 Male 9/17/2010 United States
Primary
Secondary
Concomitant
Wheezing Other Serious 5/9/1997 37 Female 193 lb 9/22/2010 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 11/1/2001 50 Female 10/1/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 11/1/2001 50 Female 10/8/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Wound Infection Other Serious 5/1/2007 68 Male 219 lb 10/11/2010 United States
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 1/1/2010 44 Male 10/12/2010 Physician France
Primary
Secondary
Concomitant
Renal Impairment Other Serious 3/1/2006 55 Male 137 lb 10/18/2010 Physician Japan
Primary
Concomitant
Wheezing Other Serious 5/9/1997 37 Female 193 lb 11/19/2010 United States
Primary
Secondary
Concomitant
Pain In Extremity Other Serious 9 Male 12/29/2010 Physician Japan
Primary
Secondary
Renal Cyst Other Serious 5/9/1997 37 Female 193 lb 1/7/2011 Physician United States
Primary
Secondary
Concomitant
Tendonitis Hospitalization 5/9/1997 37 Female 193 lb 1/26/2011 Lawyer United States
Primary
Secondary
Concomitant
Myelodysplastic Syndrome Other Serious 55 1/28/2011 Other Health Professional United States
Primary
Secondary
Hepatic Function Abnormal Death 9/18/2010 56 Male 159 lb 2/14/2011 Physician Japan
Primary
Concomitant
Cardiac Failure Death 7/25/2010 60 Female 93 lb 2/14/2011 Physician Japan
Primary
Secondary
Concomitant
Cardiac Failure Life Threatening 6/23/2010 43 Female 119 lb 2/14/2011 Physician Japan
Primary
Secondary
Concomitant
Circulatory Collapse Death 3/1/2007 22 Female 99 lb 2/16/2011 Physician Japan
Primary
Secondary
Concomitant
Generalised Oedema Hospitalization 5/9/1997 37 Female 193 lb 2/21/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Epistaxis Hospitalization 12/25/2010 64 Male 237 lb 1/25/2011 Pharmacist United States
Primary
Concomitant
Tendonitis Hospitalization 5/9/1997 37 Female 193 lb 3/1/2011 United States
Primary
Secondary
Concomitant
Cardiac Disorder Disability 1/19/2010 2 Female 22 lb 3/24/2011 Physician Japan
Primary
Secondary
Concomitant
Groin Pain Other Serious 5/9/1997 37 Female 193 lb 3/24/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Hypomagnesaemia Other Serious 1/1/1995 57 Male 3/28/2011 Lawyer United States
Primary
Secondary
Concomitant
Back Pain Other Serious 5/9/1997 37 Female 193 lb 4/5/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Tachycardia Hospitalization 5/9/1997 37 Female 193 lb 5/9/2011 Physician United States
Primary
Secondary
Concomitant
Myelodysplastic Syndrome Other Serious 3/28/2007 55 Female 5/11/2011 Other Health Professional United States
Primary
Secondary
Medulloblastoma Death 3/29/2006 3 Female 21 lb 5/17/2011 Physician Japan
Primary
Concomitant
Sepsis Hospitalization 3/12/2010 58 Female 108 lb 5/19/2011 Physician Japan
Primary
Secondary
Concomitant
Bronchial Carcinoma Death 1/26/2011 67 Male 110 lb 6/7/2011 Other Health Professional France
Primary
Secondary
Concomitant
Pyrexia Hospitalization 2/28/2004 64 Male 157 lb 6/8/2011 Physician Japan
Primary
Concomitant
Aspartate Aminotransferase Increased Hospitalization 12/20/2003 27 Female 108 lb 6/16/2011 Physician Japan
Primary
Secondary
Concomitant
Pneumonia Life Threatening 10/15/2007 40 Female 148 lb 6/22/2011 Physician Japan
Primary
Secondary
Concomitant
Constipation Hospitalization 12/10/2003 27 Female 108 lb 6/24/2011 Physician Japan
Primary
Secondary
Concomitant
Abdominal Discomfort Other Serious 5/9/1997 37 Female 193 lb 7/5/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Pneumonia Cytomegaloviral Death 6/9/2009 10 Male 64 lb 7/15/2011 Physician Japan
Primary
Secondary
Concomitant
Groin Pain Other Serious 5/9/1997 37 Female 193 lb 7/19/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Aspartate Aminotransferase Increased Hospitalization 12/10/2003 27 Female 108 lb 7/21/2011 Physician Japan
Primary
Secondary
Concomitant
Mitral Valve Incompetence Other Serious 5/1/2007 68 Male 219 lb 7/25/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Bacterial Sepsis Death 5/18/2004 51 Male 163 lb 7/25/2011 Physician Japan
Primary
Secondary
Concomitant
Blood Lactate Dehydrogenase Increased Hospitalization 5/9/1997 37 Female 193 lb 7/29/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Anaemia Hospitalization Male 8/2/2011 Physician United States
Primary
Concomitant
Acute Myeloid Leukaemia Life Threatening 1/1/2011 57 Male 8/5/2011 Consumer France
Primary
Secondary
Myelofibrosis Other Serious 1/1/2011 57 Male 8/8/2011 Other Health Professional France
Primary
Secondary
Refractory Anaemia With An Excess Of Blasts Life Threatening 1/1/2011 57 Male 8/11/2011 Other Health Professional United Kingdom
Primary
Secondary
Refractory Anaemia With An Excess Of Blasts Life Threatening 1/1/2011 57 Male 8/11/2011 Other Health Professional France
Primary
Secondary
Herpes Zoster Hospitalization 5/12/2010 58 Male 168 lb 8/12/2011 Physician Japan
Primary
Secondary
Concomitant
Refractory Anaemia With An Excess Of Blasts Life Threatening 1/1/2011 57 Male 8/12/2011 Physician France
Primary
Secondary
Acute Myeloid Leukaemia Life Threatening 1/1/2011 57 Male 8/16/2011 Other Health Professional France
Primary
Secondary
Os Trigonum Syndrome Other Serious 5/9/1997 37 Female 193 lb 8/18/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Myelofibrosis Life Threatening 1/1/2011 57 Male 9/5/2011 Other Health Professional France
Primary
Secondary
Pallor Hospitalization Male 9/6/2011 Lawyer United States
Primary
Concomitant
Myelofibrosis Life Threatening 1/1/2011 57 Male 9/7/2011 Physician France
Primary
Secondary
Viral Haemorrhagic Cystitis Other Serious 10/4/2010 68 Female 108 lb 9/7/2011 Physician Japan
Primary
Secondary
Concomitant
Aspartate Aminotransferase Increased Other Serious 12/22/2010 62 Male 161 lb 9/7/2011 Physician Japan
Primary
Secondary
Concomitant
Acute Myeloid Leukaemia Life Threatening 1/1/2011 57 Male 9/7/2011 Consumer United Kingdom
Primary
Secondary
Upper Limb Fracture Hospitalization Male 9/8/2011 Physician United States
Primary
Concomitant
Hilar Lymphadenopathy Other Serious Male 9/21/2011 Physician United States
Primary
Concomitant
Weight Increased Death 9/5/2002 49 Female 117 lb 9/22/2011 Physician Japan
Primary
Secondary
Concomitant
Eccentric Fixation Hospitalization 6/21/2011 17 Male 10/7/2011 Physician Japan
Primary
Secondary
Concomitant
Viral Haemorrhagic Cystitis Other Serious 10/4/2010 68 Female 108 lb 10/10/2011 Physician Japan
Primary
Secondary
Concomitant
Neoplasm Malignant Other Serious 8/1/2011 58 Male 10/24/2011 Other Health Professional France
Primary
Secondary
Myelodysplastic Syndrome Other Serious 8/1/2011 58 Male 10/25/2011 Other Health Professional France
Primary
Secondary
Concomitant
Leukopenia Hospitalization Male 10/25/2011 Physician United States
Primary
Concomitant
Tricuspid Valve Incompetence Hospitalization 5/1/2007 68 Male 219 lb 10/28/2011 Physician United States
Primary
Secondary
Concomitant
Malaise Hospitalization 1/1/2010 70 Male 128 lb 11/2/2011 Physician Japan
Primary
Concomitant
Posterior Reversible Encephalopathy Syndrome Hospitalization 6/21/2011 17 Male 11/8/2011 Physician Japan
Primary
Secondary
Concomitant
Posterior Reversible Encephalopathy Syndrome Hospitalization 6/8/2011 17 Male 11/9/2011 Consumer Japan
Primary
Secondary
Concomitant
Myeloma Recurrence Other Serious 8/1/2011 58 Male 11/30/2011 Other Health Professional France
Primary
Secondary
Myelodysplastic Syndrome Other Serious 8/1/2011 58 Male 12/5/2011 Other Health Professional France
Primary
Secondary
Concomitant
Myelodysplastic Syndrome Life Threatening 9/1/2011 59 Female 12/6/2011 Other Health Professional France
Primary
Secondary
Convulsion Other Serious 6/21/2011 17 Male 12/7/2011 Physician Japan
Primary
Secondary
Concomitant
Myelodysplastic Syndrome Life Threatening 9/1/2011 59 Female 12/7/2011 Other Health Professional France
Primary
Secondary
Squamous Cell Carcinoma Of Skin Other Serious 7/1/2011 71 Male 12/8/2011 Physician Denmark
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 1/1/2011 17 Male 12/9/2011 Consumer Japan
Primary
Secondary
Concomitant
Dyslalia Other Serious 6/21/2011 17 Male 12/27/2011 Physician Japan
Primary
Secondary
Concomitant
Acute Myeloid Leukaemia Other Serious 11/1/2011 67 Male 12/28/2011 Other Health Professional France
Primary
Secondary
Concomitant
Muscle Spasms Hospitalization 6/8/2011 17 Male 12/29/2011 Physician Japan
Primary
Secondary
Concomitant
Erythema Disability 9/1/2008 14 Female 110 lb 1/12/2012 Physician Japan
Primary
Secondary
Concomitant
Abdominal Pain Hospitalization Male 1/17/2012 Physician United States
Primary
Concomitant
Arteriosclerosis Coronary Artery Hospitalization Male 1/18/2012 Physician United States
Primary
Concomitant
Hypoxia Hospitalization Male 1/25/2012 Lawyer United States
Primary
Concomitant
Obesity Other Serious Male 1/30/2012 Physician United States
Primary
Concomitant
Bone Sarcoma Other Serious 2/1/2012 Physician Japan
Primary
Concomitant
Myelodysplastic Syndrome Other Serious 3/28/2007 55 Female 3/1/2012 Other Health Professional United States
Primary
Secondary
Walking Aid User Hospitalization 1/1/2002 51 Female 3/27/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Vaginal Ulceration Hospitalization 62 Female 187 lb 3/26/2012 Lawyer United States
Primary
Concomitant
Weight Increased Other Serious 1/1/2002 51 Female 4/5/2012 Physician United States
Primary
Secondary
Concomitant
Squamous Cell Carcinoma Of Skin Other Serious 7/1/2011 71 Male 4/5/2012 Physician Denmark
Primary
Secondary
Concomitant
Pulmonary Hypertension Hospitalization Male 5/10/2012 Lawyer United States
Primary
Concomitant
Sinus Tachycardia Hospitalization 1/1/2002 51 Female 7/2/2012 Lawyer United States
Primary
Secondary
Concomitant
Hypertension Death 3 Female 7/2/2012 Physician Japan
Primary
Concomitant
Neuroblastoma Life Threatening 10/1/2011 2 Male 24 lb 7/17/2012 Physician Japan
Primary
Concomitant
Myelodysplastic Syndrome Life Threatening 11/3/2011 60 Female 8/1/2012 Other Health Professional France
Primary
Secondary
Acute Myeloid Leukaemia Life Threatening 11/3/2011 60 Female 8/1/2012 Other Health Professional France
Primary
Secondary
Urinary Tract Infection Hospitalization 5/9/1997 37 Female 193 lb 8/6/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Polyp Hospitalization 1/1/2002 51 Female 8/6/2012 Consumer United States
Primary
Secondary
Concomitant

Drug Data